Low-Dose Estrogen May Help Breast Cancer Relapse Says Study

by: cancercompass

Researchers are suggesting a very low dose of estrogen might help women fighting breast cancer prevent a reoccurrence, reports Reuters.

Dr. Matthew Ellis of Washington University School of Medicine in St. Louis and colleagues studied 66 women with advanced breast cancer who were treated with an aromatase inhibitor that blocks estrogen. Some of these drugs include Pfizer's Aromasin, Novartis's Femara and AstraZeneca Plc's Arimidex. Women taking part in the study all experienced a relapse after treatment with these estrogen blocking drugs.

Doctors gave the women estradiol, a form of estrogen, in both high and very low doses. Both doses helped 30% of the women, with the lower dosage being more tolerable, according the study's findings.

Also, Reuters explains the treatment was not always permanent. In that 30% of women helped by the estrogen, the tumors did in fact start growing again. One-third of these women were helped by being placed back on an aromatase inhibitor instead of chemotherapy which is often more toxic and less tolerable.

What treatments has your doctor placed you or a loved one on to fight breast cancer relapse? Share your experience with members of the CancerCompass Breast Cancer Discussion Board.