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Mouth cancer (also called oral cancer) is a malignant growth which can occur in any part of the mouth including the lips and tongue. In the UK, the numbers of new cases have risen by over 41 per cent over the last ten years(1). About 5,325 people get cancer of the mouth each year and the disease kills one person every five hours. Treated in its early stages, mouth cancer is curable but if not detected early, it kills around one in two sufferers.
Drugs used to treat psychiatric disorders are highly effective at killing cancer cells, opening up potential new lines of treatments. Dr Louise Lurze-Mann of the University of NSW School of Biotechnology and Biomolecular Sciences was talking with psychiatric researchers at the University of Queensland when they mentioned that people with diseases like schizophrenia appear to have low rates of cancer, despite being more inclined to smoke than the general population.
One of Australia's proudest scientific achievements of recent years, the vaccine against cervical cancer, may turn out to even more important than anyone Research published in the British Journal or" Cancer suggests that the vaccine may also prevent some breast cancers.
Researchers at Yale University have developed synthetic molecules capable of enhancing the body's immune response to HIV and HIV-infected cells, as well as to prostate cancer cells. Their findings, published online in the Journal of the American Chemical Society, could lead to novel therapeutic approaches for these diseases.
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In a review article published this month in The Oncologist, UNC's Dr. Richard M. Goldberg and a team of colleagues catalogue how the data collected in a single large comparative clinical trial testing combination chemotherapy for metastatic colorectal cancer has been used not only to benefit the patients that enrolled but also patients who subsequently developed the disease.
A Dutch study that included nearly 90,000 women finds that liquid-based cytology, a commonly used alternative to conventional Pap tests, is not superior to Pap tests for the detection of cervical cancer precursors or cancer, according to a study in the October 28 issue of JAMA.
Nektar Therapeutics announced that it has completed enrollment ahead of schedule in its Phase 2 clinical study of NKTR-102 in platinum- resistant ovarian cancer. NKTR-102 is Nektar's investigational proprietary compound currently being evaluated in Phase 2 clinical development in ovarian, breast and colorectal cancers.
Uterine serous carcinomas typically have a characteristic morphology (papillary architecture, high-grade nuclei) and immunoprofile (diffuse/strong p53 expression, loss of hormone receptor expression) that distinguish them from most endometrial endometrioid carcinomas.
Results of the FDA pivotal clinical trial for the LightTouch(TM) Non-invasive Cervical Cancer Detection Device conducted by Guided Therapeutics, Inc. (GT), indicated that the current system for diagnosing cervical disease missed the same amount of disease as a landmark study carried out by the National Cancer Institute (NCI).
Results of two phase 1 studies demonstrate that the novel, investigational cancer vaccines MKC1106-MT and MKC1106-PP are well-tolerated and show encouraging immune response rates and objective tumor response in advanced melanoma, prostate cancer and other solid malignancies, setting the stage for phase 2 studies. The data are being presented at the International Society for Biological Therapy of Cancer 2009 Annual Meeting.
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