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The American Society of Clinical Oncology (ASCO) has once again recognized Erbitux(R) (cetuximab) as one of the major clinical cancer advances of 2009. This year Erbitux was selected by ASCO for providing the first significant increase in survival for 30 years in the treatment of patients with 1st-line recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN).
Oncolytics Biotech Inc. today announced that a poster presentation covering updated results of a Phase I/II U.K. trial (REO 011) of REOLYSIN (R) combined with paclitaxel/carboplatin for patients with advanced cancers will be presented on November 17, 2009 at the 2009 AACR- NCI-EORTC Molecular Targets and Cancer Therapeutics conference being held in Boston, Massachusetts.
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Accurate assessment of primary tumor size is an essential part of management in breast cancer patients. Tumor size is part of the TNM system used to stage breast cancer and provide prognostic information. Adaptation of the principles of breast conservation surgery requires evaluation of tumor size to judge appropriateness and extent of surgery. Precise measurement of tumor size is also important to monitor response to neoadjuvant chemotherapy for locally advanced tumors.
Scientists have long suspected that the soy foods in Asian diets may help explain why people in places like Japan, China, and Singapore have lower rates of breast cancer, prostate cancer, osteoporosis, and heart disease. And thousands of studies over the past two decades- most of them carried out in the West- have tried to figure out whether soybeans are beneficial and, if so, which parts of the soybean are responsible.
The number of lymph nodes analyzed in specimens from patients undergoing resection for colon cancer has diagnostic and therapeutic importance. Low lymph node number is a risk factor for poor survival, particularly in patients with Stage II and Stage III disease.
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Patients with locally advanced esophageal cancer who require neoadjuvant therapy have significant dysphagia. To prospectively evaluate Polyflex stents to treat malignant dysphagia and to ameliorate weight loss in patients with locally advanced esophageal cancer who will undergo neoadjuvant therapy, scientists in the United States report.
Current study results from the report, 'A feasibility study of sequential doublet chemotherapy comprising carboplatin-doxorubicin and carboplatin-paclitaxel for advanced endometrial adenocarcinoma and carcinosarcoma,' have been published. According to a study from the United Kingdom, Platinum compounds, taxanes and anthracyclines provide the major effective drug classes in the treatment of advanced and recurrent endometrial cancer and carcinosarcoma.
The development of stomach cancer is closely associated with chronic inflammation, and the Wnt/beta-catenin signaling pathway is activated in most cases of this cancer. High-mobility group A (HMGA) proteins are oncogenic chromatin factors that are primarily expressed not only in undifferentiated tissues but also in various tumors, scientists writing in the American Journal of Pathology report.
According to recent research from the United States, Radiosurgery for brain metastasis fails in some patients, who require further surgical care. In this paper the authors' goal was to evaluate prognostic factors that correlate with the survival of patients who require a resection of a brain metastasis after stereotactic radiosurgery (SRS).
Endocyte, Inc., a cancer drug discovery and development company, presented data from a Phase 2a clinical trial for EC145, currently in development as a potential treatment for advanced ovarian cancer.
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