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Studies Point To Benefits Of Personalized Chemotherapy Dose Management In Colorectal Cancer
POSTED: May 9, 2008Can a blood test improve treatment outcomes for colorectal cancer patients? Recently published studies indicate that personalized chemotherapy dose management -- measuring drug levels in patients' blood and adjusting them for optimal dosing -- can substantially reduce severe toxicity and improve efficacy in colorectal cancer. A Phase III randomized s...
Investigators At American Cancer Society Have Published New Data On Colon Cancer Epidemiology
POSTED: May 9, 2008Fresh data on colon cancer are presented in the report 'Colonoscopy surveillance after polypectomy and colorectal cancer resection.' "This article describes a joint update of guidelines by the American Cancer Society and the U.S. Multi-Society Task Force on Colorectal Cancer delineating evidence-based surveillance recommendations for patients after poly...
Studies From National Cancer Institute Yield New Information About Colon Cancer
POSTED: May 9, 2008According to a study from the United States, "Sulindac is a nonsteroidal antiinflammatory drug that has been demonstrated to be a potent chemopreventive agent against colorectal cancer in both human and animal models. In vivo, sulindac may be reversibly reduced to the active antiinflammatory compound, sulindac sulfide, or irreversibly oxidized to sulind...
Curis Announces Genentech's Initiation Of Hedgehog Antagonist Phase II Clinical Trial In Metastatic Colorectal Cancer
POSTED: May 9, 2008Curis, Inc., a drug development company focused on developing the next generation of proprietary targeted medicines for cancer treatment, announced that its collaborator Genentech has initiated a Phase II clinical trial of GDC-0449, an orally-administered small molecule Hedgehog antagonist, in metastatic colorectal cancer. As a result, Genentech will ma...
IUDs Can Help Prevent Uterus Cancer
POSTED: May 9, 2008Contraceptive intrauterine devices can help to protect women from a type of cancer, researchers have claimed. Scientists from the Family Health International in Chapel Hill, North Carolina, claim the IUDs can not only prevent unwanted pregnancies, but can also prevent endometrial cancer, which effects the uterus. Dr. David Grimes, who worked on the stud...
Cancer Could Return Unless Stored Ovarian Tissue Undergoes Adequate Testing Before Re-implantation
POSTED: May 9, 2008Cancer patients who have been successfully treated for their disease face the prospect of its return if stored ovarian (or testicular) tissue is transplanted back into their bodies without adequate checks, according to researchers at two university hospitals in Israel. Writing in Europe's leading reproductive medicine journal, Human Reproduction, tod...
When To Wait And When To Treat? New Program Will Search For Biomarkers In Men With Prostate Cancer To Help Find An Answer
POSTED: May 9, 2008Researchers at Fred Hutchinson Cancer Research Center have a lead role in a new public/private partnership to create the first systematic surveillance program of men with prostate cancer to look for biological clues to help determine when to wait and when to treat the disease. The project was announced by the Canary Foundation and the National Cancer In...
Canary Foundation And The National Cancer Institute Launch New Prostate Cancer Study
POSTED: May 9, 2008The Canary Foundation, a nonprofit organization that funds research in early cancer detection, and the National Cancer Institute's Early Detection Research Network (EDRN), jointly announced that the two organizations are forming a partnership for the purpose of identifying and validating biomarkers of high-risk prostate cancer within the context of an a...
Health Discovery Corporation Announces Successful Clinical Trial Results For New Molecular Diagnostic Test For Prostate Cancer
POSTED: May 9, 2008Health Discovery Corporation ("HDC") announced the successful clinical trial results for HDC's new molecular diagnostic test for prostate cancer licensed exclusively to Clarient, in which HDC will receive a 30 percent royalty based on reimbursements received by Clarient from third parties. The initial clinical validation study recently completed at C...
New Study Raises Questions About Prostate Cancer Therapies Targeting Insulin-like Growth Factor Receptor
POSTED: May 9, 2008Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results, especially if a major tumor suppressor gene -- p53 -- is already compromised, according to new research by investigators at Fred Hutchinson Cancer Research Center. IGF-1 is...
