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Amgen today announced detailed results from the Phase 3 '203' trial evaluating Vectibix(R) (panitumumab) administered in combination with FOLFOX (an oxaliplatin-based chemotherapy) as the first-line treatment of metastatic colorectal cancer (mCRC).
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Additionally, results of a meta-analysis demonstrate clear survival and tumor response benefits of Erbitux in this setting with FOLFOX or FOLFIRI.
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Two new blood tests can aid in the early identification of patients with gastrointestinal cancers, researchers in Belgium have found.
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OncoMethylome Sciences is announcing today promising results from its on-going evaluation of a blood-based methylation assay for the screening and detection of colorectal cancer (CRC). The results are being presented on Monday, September 21st at the 15th Congress of the European Cancer Organization and 34th Congress of the European Society for Medical Oncology in Berlin, Germany.
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New investigation results, 'Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer,' are detailed in a study published in British Journal of Cancer. In an earlier study, a 25- hydroxyvitamin D(3) (25(OH)D) score calculated from known predictors of vitamin D status significantly predicted plasma levels of 25(OH) D and the risk of colorectal cancer, but the influence of the 25 (OH)D score on survival after diagnosis is unknown.
New research led by scientists at the University of North Carolina at Chapel Hill School of Medicine have found a drug target that suggests a potent way to kill colon cancers that resist current drugs aimed at blocking a molecule found on the surface of cells.
We report here the efficacy of dietary antioxidants in combination with chemotherapy on tumor growth in the orthotopic COLO-205-green fluorescent protein (GFP) human colon cancer mouse model. The orthotopically-transplanted nude mice used for the study were randomly divided into 5 groups (A-E) after surgical orthotopic implantation (SOI) of tumor tissue, scientists writing in the journal Anticancer Research report.
Several studies have suggested that the n-3 fatty acids Docosahexaenoic (DHA) and Eicosapentaenoic (EPA) have an important protective effect on colorectal cancer, and this could be at least partly due to their proapoptotic activity. It is unclear, however, how this phenomenon is triggered and what mechanisms are implicated,
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Published today, as an original investigation, in the peer-reviewed Journal of Clinical Oncology, are statistically significant Phase II clinical results of The GI Company's lead clinical compound, rhITF (recombinant human Intestinal Trefoil Factor) oral spray.
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A close relative of a well-known fruit tree found in Ukambani, Taita and Voi could hold the key to a cure for some of the world's untreatable cancers. Commonly known as soursop or custard apple, the plant belonging to the Annona species has shown dramatic success in destroying lung, breast, prostate, colon, liver, ovarian, cervical, breast, bladder and skin cancerous cells.
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