Visit our online cancer treatment forum for additional resources and information about current or upcoming clinical research trials. http://www.cancercompass.com/message-board/cancer-treatments/clinical-trials-and-research/1,0,129,81.htm Mon, 23 Nov 2009 00:00:00 GMT Mon, 23 Nov 2009 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ My small group operated on a 8 year old boy in Haiti in September. Kerven had a very large and painful tumor in his eye that turned out to be Lymphoblastic Lymphoma.  We resected the tumor and surrounding bone. We are now looking for a hospital that will donate the necessary chemo and radiation treatment. If you can help we would appreciate it.   Tom F. RNSurgical volunteers International--Message edited by CancerCompass staff. For personal protection, email address removed. Consider private reply. Please review CancerCompass Member Guidelines at http://www.cancercompass.com/common/guidelines.html--   http://www.cancercompass.com/message-board/message/all,40694,0.htm urologynurse Thu, 15 Oct 2009 00:00:00 GMT Hi there! Is anyone here currently in the Brivanib trial at MSK? My sister's doctor at Dana Farber wants her to look into this. I appreciate any help/information that you can give. She has primary anagiosarcoma of the breast that metastisized (sp)to the lungs, sternum, and ovary. She has had radiation for the lungs/sternum and is currently on doxil. Thanks! Lisa http://www.cancercompass.com/message-board/message/all,40718,0.htm lisalisa08 Thu, 15 Oct 2009 00:00:00 GMT This scientific study published this year may of benefit to you. http://www.ncbi.nlm.nih.gov/pubmed/19368145?ordinalpos=1&amp This time tested natural substance from the biblical times and beneficial in many conditions does not have any significant side effects though may taste a little horrible. http://www.cancercompass.com/message-board/message/all,40554,0.htm liz135 Sat, 10 Oct 2009 00:00:00 GMT I'm sure everyone here knows someone with cancer or who had cancer. I just wanted to give everyone a little hope that we might be getting closer to a cure. I've only played a very small part with this company on and off again for the last couple of years. Let's all pray that they are successful, for everyone's sake. Just watch the video for details....amazing stuff.http://www.wyff4.com/video/20206707/?taf=gs    http://www.cancercompass.com/message-board/message/all,38546,0.htm JNG855 Wed, 29 Jul 2009 00:00:00 GMT I have stage IV Pancreatic Cancer and I was treated with a Chemotherapy of Gemzar and an experimental drug.  However, the chemo only worked from January to the end of June. By the middle of June the tumors in my lungs started growing and more and there were new ones and there was a new spot on my liver so I was taken off of the study.  So now I am being told that I am in my second line of defense with the disease and the doctors are telling me that that my cancer is very aggressive and even harder to treat because my body has been exposed to the Gemzar.  At this point, the only thing I am being offered is a drug called Fulfox (not sure of the spelling) but this chemo is a lot more toxic and only works in 20% of the patients and it usually causes numbness and possible nerve damage in your hands and feet.  I was told to "shop around and see what else is available; if there are any natural alternative, clinical trials or anything that anyone know might work for someone who has had Gemzar already and is in their second line of defense with this disease.  I am a 50 year old female and I don't want to die.If anyone knows of anything I would really appreciate it.Sincerely yours, http://www.cancercompass.com/message-board/message/all,38320,0.htm onlynphilly Wed, 22 Jul 2009 00:00:00 GMT I'm looking for help for my mom who has just has 1 chemo treatment of Taxotere for her tumors that have started growing on her spine after removing a cancer in her nasal cavity along with her sinus cavity. The pressure of the tumor on her spine has crushed 3 vertebrae and the doctor has stopped the chemo due to her insurance not paying for chemo and for her care in a facility. Prior to 25 days ago she lived alone and now requires help 24/7. I feel they have given up due to the lack of research on the type of cancer she has. I feel she could still benefit from treatment. Otherwise she has been sentenced to die in this facility. 1 treatment is not sufficient to determine that it could not help her. If you can help me find a trial or research facility to make an effort to help her I would appreciate the information as soon as possible. http://www.cancercompass.com/message-board/message/all,38280,0.htm Dizzy0557 Tue, 21 Jul 2009 00:00:00 GMT Hi again:Lots of questions. Has anybody on here have NHL that has relapsed and has been through a clinical trial that worked. I am waiting for a bone marrow transplant but am scared to do it since I have read of so many patients dieing from it after suffering months.I know if I don't do something else I will die. I have heard of clinical trials working but don't have the slightest idea which ones and was wanting to find out if anybody on here has chosen to go through one and it helped.Thank youPaul   http://www.cancercompass.com/message-board/message/all,37730,0.htm retasueus Fri, 03 Jul 2009 00:00:00 GMT I have a friend that has a coloscopy bag and she is wondering if there is any special waterproof bags that can be purchased to put over the coloscopy bag while taking a shower. If anyone has another source other than a trash bag and tape would love to hear from you. She still works so it's very hard for her to do this routine before work every morning.Thanks to all and God Bless.Anna http://www.cancercompass.com/message-board/message/all,37690,0.htm annielou Thu, 02 Jul 2009 00:00:00 GMT I am waiting to begin a clinical trial at MD Anderson taking Pomolidamide.I have myelofibrosis and have been through two other trials that didn't result in any improvement.Would love to talk with others who have this and what treatment you are on or have tried.I am 58 and was diagnosed May 2008.Thanks,Janet/Nana http://www.cancercompass.com/message-board/message/all,37548,0.htm JanetNana Sat, 27 Jun 2009 00:00:00 GMT Hello everyone,  I was reading about the efffects of paxil and that it helps with the memory issues.  I really don't know if it helps with that but it does take alot of anxiety away.  Sometimes it takes to much emotions when you should be emotional you aren't kind of like okay i am aware of what is going on but there is no feelings.  Sometimes this is good sometimes bad.  Well i am still on it.  Will keep you posted.  johelen http://www.cancercompass.com/message-board/message/all,37252,0.htm johelen Thu, 18 Jun 2009 00:00:00 GMT My other half has a psa of 72 and a gleason of 8. We talked to the urologist after the biopsy and bone scan and mri. He said the cancer is contained within the prostrate but pushed surgery, the other options are radiation w/ hormone treatement and also the option of the clinical trials of RTOG 0521 which has an option of hormone and radiation or the hormone and radiatin and chemo depending on which group you are assigned. Has anyone out there have input on this clinical trial. The surgery does sound like it could be devastating to the patient and we are not waying this option. http://www.cancercompass.com/message-board/message/all,36877,0.htm jjjto Sat, 06 Jun 2009 00:00:00 GMT I have been treated for lung cancer. I live in California, but my doctor says he is unable to locate any way to obtain compassionate care use of this drug for me. It seems this is all I can find, and conventional therapies have had no value. I really need to find a way to try this drug. Does anyone know how? A phone number or anything? Thanks! I've been calling Calando Pharmaceuticals to no avail. http://www.cancercompass.com/message-board/message/all,36413,0.htm victorias2 Fri, 22 May 2009 00:00:00 GMT dx sept 2007 first round taxol and carbo, ca125 went to 5....six months later up to 50 startedon taxol carb doxil (one of them I go Ip0 remission 5 months. relapse carb, taxol, avastin (37000 a month just for that) every omnday for 21 weeks until i got chemo toxic...no short term memory-went to hosp for 6 days,dont remember, had kids over for dinner and lunch-dont remember..lost days...Im a nurse so had to stop working. now taking 1/2 less taxol as maintenance dose, with prn liters of saline in attempt to defray neurologic side affects. My sister and I are BRACA1, I really feel like the genetic approach is our only hope. However we live in bum pluck alaska.......its like pulling hens teeth getting any infomation, its been almost 3 years and I just found out that there is a clinical trials "office" somewhere in the bowels of the new cancer center in anchoragel. So frustrating...No one has asked me hows my nutrition lo Ive lost 60 pounds and eat once or twice a week, I cry more now that I did when first dx and yet no one asked me if I need a counselor..your really on your own. The sad part of it is that Im an experience ER/Med surg nurse...I SPEAK the lingo and I still have a hard time advocating for myself. My sister and I are going to see the cancer treatment center of americca in airzonea (sp) this summer in hopes of getting some info for a high quality of a life. My sadness increases each day for the grandchildren I have and the ones I havent seen born yet. I just dont want to let do. Im so so sorry so many of you have pains like this, as a nurse I had no idea of the sleepless nights and the sorrow thinking of your loved ones, forgive me.  http://www.cancercompass.com/message-board/message/all,36136,0.htm Redboots Thu, 14 May 2009 00:00:00 GMT Does anyone know of any trials being conducted on stage four small cell lung cancer that has spread to the brain, adrenal, liver and kidney?  Conventional treatment is still ongoing, but it is not working.  Also, we need some information in the area of caregiving for as the cancer gets worse the patient's personality grows harsher and more, what I call, schizo.  My sister, the patient, has always been difficult, actually downright nasty, if you asked my children, but now it is getting to the point of out and out cruelty.  We know she is scared and angry but we need to know how to be with her to help.  Cracks are beginning to appear in my other sister and my sister's daughter,  her three caregivers.  This cancer is not about us but we do care for her, so we need some help. http://www.cancercompass.com/message-board/message/all,36140,0.htm cadyjordan Thu, 14 May 2009 00:00:00 GMT Brand new to the site. My best friend was dx with Fallopian Tube Cancer (Stg3?) in 2004. I had breast cancer in "06" & we attend a support group together. From the beginning Penny was adamate that she only wanted to know the here & now. She has NEVER reserched her cancer for fear of finding out more information then she wanted to know. That is not to say she did not read anything but she never wanted to know the survival rate.When she was dx I went on line & found out of the limited #'s being reported, saw all kinds of confusing information. I respected her wish NOT to know anymore then what the Doc told her I & her family stepped back. However, the support group we are involved in has encouraged me to go back & see if things have changed.Ladies, I am overwhelmed with the links. We live in New Hampshire.My question to all readers is how can we find out what "cancer center" has treated the "most cases"? Thanks beforehand on responses, Franny  http://www.cancercompass.com/message-board/message/all,35084,0.htm SisterFaith Wed, 08 Apr 2009 00:00:00 GMT I had a radical left neph done 2/2/09 at UCSF. The doctor and staff are wonderful and supportive. I was offered this opportunity to be involved in this important clinical study. For those who are also involved, do you have any words of wisdom or advice? I would really appreciate hearing from you. I'm nervous about the medication side-effects, still being able to work, etc. Thank you! http://www.cancercompass.com/message-board/message/all,33786,0.htm Sstevens Mon, 02 Mar 2009 00:00:00 GMT ScienceDaily (Dec. 1, 2008) — If you're a cancer cell, you want a protein called Bcl-2 on your side because it decides if you live or die. It's usually a trusted bodyguard, protecting cancer cells from programmed death and allowing them to grow and form tumors. But sometimes it turns into their assassin.Scientists knew it happened, but they didn't know how to actually cause such a betrayal. Now they do. And it may lead to the development of new cancer-fighting drugs.Researchers at Oregon State University and the Burnham Institute for Medical Research in La Jolla, Calif., have developed a peptide that converts the Bcl-2 protein from a cancer cell's friend to a foe."Now we can force this protein to backstab the cancer cell where it resides," said Siva Kolluri, an assistant professor of cancer biology in the environmental and molecular toxicology department at OSU. He's also the lead author of an article that reported the discovery in the Cancer Cell journal in October.The key to the conversion is peptide NuBCP-9, a string of nine amino acids that bind to Bcl-2 and attack the mitochondria, the powerhouse of cells. Researchers derived it from Nur77, a nuclear receptor that can cause cells to die. To see if it worked outside the petri dish, researchers injected the peptide and its mirror-image molecule into cancer tumors in mice and found that the cancer cells died and the tumors shrank. To their surprise, they also found that a structurally mirrored-image stable peptide worked as well as the original peptide.The findings could lead to the development of cancer-fighting drugs that target Bcl-2, Kolluri said. He explained that Bcl-2 is an attractive drug target because its levels are elevated in a majority of human cancers and it is responsible for cancer cells' resistance to many chemotherapeutic drugs and radiation.Michael Melner, a scientific program director at the American Cancer Society in Atlanta, Ga., said the research Kolluri and his team did "will cause a lot of attention in the cancer field.""These investigators have done a nice job of combining findings of a basic nature as well as the preliminary studies needed to move to a preclinical evaluation. It's unusual for one single paper to make such a large step forward," he said.Now one of the next steps, Melner said, is for researchers to determine what types of cancer and what stages of the disease this deadly Bcl-2 converter would combat.Linda Wolff, a leukemia researcher at the National Institutes of Health's Center for Cancer Research in Bethesda, Md., said the researchers' discovery is "rare" in the world of cancer research. She added that it's important for two reasons."First, it may lead to a therapy that could potentially be used against many types of cancer," she said. "The reason for that is because it targets Bcl-2, and Bcl-2 is expressed in many types of cancers. So it could be useful in breast cancer and other carcinomas and leukemia, for example."The second reason it's important is that although the peptide they studied causes cancer cells to die, its effect on normal cells seems to be quite minimal," Wolff said. "A big problem in cancer research has been getting therapies that don't kill normal cells."Dr. David Hockenbery, a member of the Clinical Research Division at the Fred Hutchinson Cancer Research Center in Seattle, Wash., said that this new way of altering a protein so it injures a cell rather than merely disables it "is very unusual." He added that this finding would spur researchers to develop drugs or stable peptides that act on Bcl-2 at the Nur77 binding site."Quite conceivably, individual cancers may respond better to one type of Bcl-2 inhibitor than another," he said. "In the future, the availability of several targeting approaches against Bcl-2 should be useful in personalized cancer therapies."In addition to OSU and the Burnham Institute, the other contributors to the research came from the University of Oklahoma Health Sciences Center and Xiamen University in China. Kolluri started the research project in 2003 when he worked at Burnham.Journal reference:Kolluri et al. A Short Nur77-Derived Peptide Converts Bcl-2 from a Protector to a Killer. Cancer Cell, 2008; 14 (4): 285 DOI: 10.1016/j.ccr.2008.09.002 http://www.sciencedaily.com/releases/2008/11/081125113114.ht http://www.cancercompass.com/message-board/message/all,33356,0.htm jcr65566 Thu, 19 Feb 2009 00:00:00 GMT I am due to start treatment for melanoma in the lung Feb 20. Two different doctors are in no hurry to treat it. Don't know why. Maybe because I also have Heart Disease and am 77 yrs old (male)I asked my Dr. about Clinical Trials and she said I didn't qualify as I had a bit of lung cancer a year ago.    WHO IS IT THAT MAKES DECISIONS OF CLINICAL TRIALS?    I go to a large cancer treatment center in Nebraska and my Dr. works there. I just don't understand what all is going on. http://www.cancercompass.com/message-board/message/all,33111,0.htm clf107 Wed, 11 Feb 2009 00:00:00 GMT The following link is the trial website.http://www.clinicaltrials.gov/ct2/show/NCT00826085 http://www.cancercompass.com/message-board/message/all,32841,0.htm seasky Wed, 04 Feb 2009 00:00:00 GMT Hello:I wanted to find out if there is anyone who has or has had Breast Cancer and has been experiencing any fatigue.  The doctor who I am working for is conducting a study which may provide an opportunity to relieve fatigue associated with Breast Cancer treatment.  The study is being conducted at the University of Connecticut, in Farmington.  For anyone who may be interested in participating or just finding out any further information, please e-mail me and I would be more than willing to help.   Thank you for your time,Toula--Message edited by CancerCompass staff. For personal protection, email address removed. Consider private reply. Please review CancerCompass Member Guidelines at http://www.cancercompass.com/common/guidelines.html-- http://www.cancercompass.com/message-board/message/all,32784,0.htm TOULA Tue, 03 Feb 2009 00:00:00 GMT I'm a stage 4 colorectal cancer patient.  I'm considering trying a new vaccine trial program for patients with colorectal cancer that had metastases removed from either liver or lung or both with no recent recurrance.  Has anyone every tried a vaccine trial program for their colorectal cancer?  What was your experience? And did it help? http://www.cancercompass.com/message-board/message/all,32441,0.htm rugrat01 Fri, 23 Jan 2009 00:00:00 GMT My husband has been taking revlimid but rbc is still low. Has enlarged spleen and minimal bone marrow function. Any other studies in progress. He is 67 yrs and has been symptomatic for one year. http://www.cancercompass.com/message-board/message/all,32339,0.htm maxfred Tue, 20 Jan 2009 00:00:00 GMT I was dx with stage 4 ovarian cancer 2 years ago. I had the standard treatment of 6 cycles of carboplatin and taxol and was in remission for a year before the cancer returned. I am now in a clinical trial, taking an oral drug, AZD6244. I have been on this for 9 months now and am having very good results. The tumors have stopped growing. I was wondering if anyone else was on this drug and what their experience has been.Thank you.Holly http://www.cancercompass.com/message-board/message/all,31414,0.htm HOLLY7 Sun, 21 Dec 2008 00:00:00 GMT I am 36 years old and have just been diagnosed with papillary renal cancer.  They have told me there are no ongoing trials for this type of cell. I have had my kidney removed and it has spread to my lungs and bones. Can anyone help, does anyone have any information on any trials or any other medication which could help me.Please help Lynda http://www.cancercompass.com/message-board/message/all,31252,0.htm please_help_urgent Tue, 16 Dec 2008 00:00:00 GMT I am currently in a trial at DFCI for my brain tumor. Anaplastic astrocytoma Grade III/IV. Since I've been on this I feel so sick. The Zolphran is not working. Is anyone else on this trial? I have an appt tomorrow and I was just wondering if anyone could tell me what helped them through this. I thought it was the increased dosage of Temodar, but I only had to take the for five days. I don't want to be a quitter. And I'll suck it up if I have to. Merry Christmas and Happy Holidays!Christine http://www.cancercompass.com/message-board/message/all,31201,0.htm garsmom Mon, 15 Dec 2008 00:00:00 GMT