It sounds positive that the cancer has not progressed into major organs. So my doctor assurred me that I had a chance of living a normal life after my treatments if it wasn't in my major organs, but again there is never any guarantee in life. The lymph nodes are less of an issue, but always a concern. Go with a proactive approach that is being recommended. You have to remember this treatment is harsh and it kills the bad as well as the good cells. I went with a program that was more proven at my hospital with 5FU chemo (which was many), rectum removal with resection (j-pouch), and many radiation treatments. Read everything possible on utilizing alternative type medications (over the counter type things) that may help restore him to better health. Be careful having him take a lot of pain medication. It will be a long road to recovery if he gets dependent on pain meds.
I decided that I would not only do what the doctors instructed, I exercised each day (to help mind and body strong), drank a lot of liquids (gatorade/water), ate regular and good balanced meals (even if it made me sick), and just decided to keep moving and keep my schedule as regular as possible with work and home life. The only difficulty was when I was using a continuous infusion pump to push the chemo in me for 7 weeks. I had some incredible experiences with my temporary bag in meetings when they broke! But we all laughed and made jokes. All I can say keep him moving as much as possible. It has been a proven fact in written literature that exercise is becoming the key to ongoing good health and quicker recovery with cancer patients. Use ensure or any type of protein drink when he is feeling weak. Hydrate, Hydrate, Hydrate always and keep a water bottle! Exercise- start walking a block, then move to two blocks and before you know it, the exercise is just routine and you are going around the neighborhood.
With experimental or newer drugs you have to see how things go. He really needs to keep fighting and make each day count. If he opens his eyes he will see people worse off fighting some terrible battles with cancer. He can make this a life changing positive experience.
I do wish you both well. This impacts the entire family. I have a friend who is fighting terrible breast cancer (stage 4) with a brain tumor. She is fighting and winning. Postive mental attitude, exercise, regular life schedules is so key for success. You sound like you are the "Rock". My wife helped push me so much. I thank the Lord for her. So don't baby him. Be strong and forceful to a point. You will know when to push and when to let up. You keep telling him, you need him around.
So blessings to you both. Keep in touch.