Stg Iv Colon Caner w/ Liver Mets and Peritoneal carcinomatosis

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Stg Iv Colon Caner w/ Liver Mets and Peritoneal carcinomatosis

by Maff62 on Sat Mar 10, 2007 12:00 AM

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Just wondering if there are any others out there with peritoneal carcinomatosis. My loved one was diagnosed in Aug 2006 with colon cancer with mets to the liver and "seeds" in the peritonial cavity. I read all the reports of the ct scans and never paid attention to these "seeds". I just assumed they were part of the metastisizing process - on the way to the liver. It now seems like these peritoneal "seeds" of cancer may be a seperate condition/issue. I have "googled" peritoneal carcinomatosis and it doesn't sound good. Afetr 4 1/2 months - 9 treatments of Folfox with Avastin the CT scan showed everything shrunk with no further mention of the peritoneal diease and the Pet Scan showed "no abnormal activity". Finally, surgery was scheduled to remove the colon tumor and to resect the liver.Went for surgery in Feb 2007 ( had to wait at least 6 weeks since last chemo because of risk for bleeding from Avastin) but 100's of these "seeds" were immediately observed in the abd/peritoneal cavity and surgery was stopped. The surgeon stated these "seeds" didn't show up on the cat or pet scans because they were too small. So he said so far we had excellent response to the chemo ( these "seeds" used to be as big as dates and now were as small as lentils) and recommended more chemo. We went back to our original oncologist and restarted the Avastin, stopped Folfox because of neuropathy and also started oral Xeloda. Is there anyone battling this condition with sucess?

Thanks for any informtion you can offer. God Bless.

Bernadette

RE: Stg Iv Colon Caner w/ Liver Mets and Peritoneal carcinomatosis

by Plumas_Sierra on Sat Mar 10, 2007 12:00 AM

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Yes, my husband has the same, along with met to his lungs.  We have been battling this since April 05.  Started out as colon cancer.  We are seeing a homeopathic md/onco in Reno Nevada.  We would highly suggest you seek out his advice, and he has FIT treatments, that boost the immune therapy, and also a Germany Blood Test, which analyzes blood to determine which chemotherapy is the right chemo.  I would highly suggest you do this.  My husband had Folfox, horrible side affects, come to find out, it wasn't the right drugs, neither was Avastin, but everyone is individual and genetics are equally unique.  His number is 775-827-0707.  Hope this helps, and God Bless you too!!! Linda

RE: Stg Iv Colon Caner w/ Liver Mets and Peritoneal carcinomatosis

by Sandy_p on Sun Mar 11, 2007 12:00 AM

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I am very interested in the peritoneal carcinomatosis that you mention. My mother has just undergone surgery for stage 4 colon cancer. She also has the peritoneal spread. From what I've read the peritoneal sites are hard to reach via traditional chemo, though maybe IP chemo might work? Any advice out there from someone who has dealth with the peritoneal spread? Is it a fatal condition? Can it be treated just like the rest of the colon cancer cells?

RE: Stg Iv Colon Caner w/ Liver Mets and Peritoneal carcinomatosis

by Jawman2 on Sun Apr 01, 2007 12:00 AM

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On 3/10/2007 Maff62 wrote:

Just wondering if there are any others out there with peritoneal carcinomatosis. My loved one was diagnosed in Aug 2006 with colon cancer with mets to the liver and "seeds" in the peritonial cavity. I read all the reports of the ct scans and never paid attention to these "seeds". I just assumed they were part of the metastisizing process - on the way to the liver. It now seems like these peritoneal "seeds" of cancer may be a seperate condition/issue. I have "googled" peritoneal carcinomatosis and it doesn't sound good. Afetr 4 1/2 months - 9 treatments of Folfox with Avastin the CT scan showed everything shrunk with no further mention of the peritoneal diease and the Pet Scan showed "no abnormal activity". Finally, surgery was scheduled to remove the colon tumor and to resect the liver.Went for surgery in Feb 2007 ( had to wait at least 6 weeks since last chemo because of risk for bleeding from Avastin) but 100's of these "seeds" were immediately observed in the abd/peritoneal cavity and surgery was stopped. The surgeon stated these "seeds" didn't show up on the cat or pet scans because they were too small. So he said so far we had excellent response to the chemo ( these "seeds" used to be as big as dates and now were as small as lentils) and recommended more chemo. We went back to our original oncologist and restarted the Avastin, stopped Folfox because of neuropathy and also started oral Xeloda. Is there anyone battling this condition with sucess?

Thanks for any informtion you can offer. God Bless.

Bernadette


Hi, I'm 43 and was diagnosed with peritoneal mets. in Oct. last yr. after intestinal obstruction and abdominal surgery....ne resection.No mass by CT scan but my Doctors think it came from the appendix or colon. I have been on Folfox and Avastin with reduction in CEA and improvement in symptoms. Repeat PET scan also showed resolution of peritoneal uptake but since they can't find the primary, I'm not a surgical candidate and am continuing Chemotherapy.

 Since regular chemotherapy doesnot go into the peritoneum very well, some patients are candidates for a surgical procedure called omentectomy along with giving warm chemotherapy into the peritoneum during the surgery. I think the liver mets. would have to be resectable in order for this procedure to be successful. There are a few surgeons specializing in this procedure...the two that i know of are:

1.  Dr. Perry Shen at Wake Forest University Baptist Medical Center, Winston Salem NC 27157. Ph: 336 716 0545.

2.  Dr.s Sugarbaker and Steve at Washington Hospital Center's Cancer Institute, on Irving ST. in Washington DC.

 You could probably ask your oncologist to get more info. on this procedure and if your loved one is a candidate.

 Good Luck.

Jawad.

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