I was diagnosed with MM in July 2004. From what I read, I guess, to date, 3 1/2 years later, I am one of the lucky ones, not metastatic. It was in my sinus. Other than having half my nose cut out (and 5 surgeries) I am still performing at 100%. At that time, I read all I could, which was not very much -- basically a 10-40% 5 year survival, surgery being the only proven solution, with chemo, biotherary, and radiation all being not proven effective at all. There use to be a site, no longer supported, by Susan (daughter of a victim of MM) with all links. Unfortunately, her father died, and it seems she did not keep the site up. Since this is very rare, there is not any updating publications or any specific research. I was doing yearly PET scans, but another Onco stated that it will not identify any tumors until they are large, suggesting that it is too late by then, or that you would have noticed it by then anyway (pain?). It would be nice if there was a blood test (like the one they do for Prostates) to even give us a clue if there is something happening. If any breakthroughs happen, it will probably be from Cutatious Melanoma, which is much more common. The vaccine looked interesting for a while, but my understanding is that it proved marginally successful. My theory is that if a neutral researcher does any pure statistics on all the radiation, chemo and vaccine that are marginally successful, it would be a wash with placebos, meaning they are not hitting the target. We will all keep waiting and watching and hoping for a true breakthrough. In the interim, good luck, we all really need it.