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Velcade In Early Stages

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K&rpromotions
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Subject: Velcade in early stages
Date: 05/02/2007

Does any know about using velcade early in treatment? My father-in-law has only know about the multiple myeloma for 6 months and the doctors are switching to velcade after only 5 treatments of the Thalidomide and dexamethasone. I have only hear stories that it is reserved for last resort kind of treatement. We thought he was almost ready for a SCT but what now? THANKS 

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Commonsense
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Subject: RE: Velcade in early stages
Date: 05/06/2007

 Velcasde is considered a last resort medicine..Have they tried revalmid.  you might want to go to www.cancercenter.com  they have live discussions and alternative treatments.

On 5/2/2007 K&rpromotions wrote:

Does any know about using velcade early in treatment? My father-in-law has only know about the multiple myeloma for 6 months and the doctors are switching to velcade after only 5 treatments of the Thalidomide and dexamethasone. I have only hear stories that it is reserved for last resort kind of treatement. We thought he was almost ready for a SCT but what now? THANKS 


 

Subject: RE: Velcade in early stages
Date: 05/22/2007
Velcade is not a medicine of last resort anymore.  I was diagnosed March 2nd 2007 and my first four rounds of chemo were doxil, velcade, and dex.  The combo worked beautifully and I am now disease-free.  When they found the mm my b2m was almost 9 and my bone marrow was over 90% cancer.  Now they can't find it.  I'm going to have an allo transplant in June while the cancer is gone and hopefully it will stay "gone".  Oh, they used this combo of chemo on me because 1- I'm young (43), and 2- because I have the mm that is from chromosomal 13 damage/and have several translocations/and is bence-jones light chain.  Guess this chemo works better on this kind of mm.  From what I can see, things are changing fast when it comes to mm and treatments.
Patient
Patient
Patricia B.
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Subject: RE: Velcade in early stages
Date: 06/07/2007

 

On 5/22/2007 Michelle13 wrote:

Velcade is not a medicine of last resort anymore.  I was diagnosed March 2nd 2007 and my first four rounds of chemo were doxil, velcade, and dex.  The combo worked beautifully and I am now disease-free.  When they found the mm my b2m was almost 9 and my bone marrow was over 90% cancer.  Now they can't find it.  I'm going to have an allo transplant in June while the cancer is gone and hopefully it will stay "gone".  Oh, they used this combo of chemo on me because 1- I'm young (43), and 2- because I have the mm that is from chromosomal 13 damage/and have several translocations/and is bence-jones light chain.  Guess this chemo works better on this kind of mm.  From what I can see, things are changing fast when it comes to mm and treatments.

Hi Michelle,

Actually they recommend Velcade after you have had one treatment that has not worked.  I have been with Velcade since the beginning trials and nobody at Dana Farber Cancer Center has ever mentioned it being a last resort thing.  I do know that Velcade is being used along with other drugs which enhance ability to heal. There does seem to be alot of rumors about Velcade and I would say talk to an expert myeloma oncologist and don't listen to people that have only heard these things by hearsay. There are so many options right now for treatment, clinical trials are the way to go in my opinion, I am on a new drug which is in phase 1 and i have hardly any side effects and my M spike has dropped from 1.1 to .95 in just 2 three week cycles.

Where there's life there is HOPE

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katie111777
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Subject: RE: Velcade in early stages
Date: 07/09/2007

Wow!  You put a smile on my face!  My dad (51) was taking revlimid for three months with no significant results.  He's now been changed to velcade/ doxil.  I am so scared but hearing your story made me feel better!  God Bless!

Subject: RE: Velcade in early stages
Date: 12/23/2007
Unfortunately it is not always the case. Mom was treated with velcade+dex+thal. Was cleared in August, but the disease came back in November. She is on Revlimid now...
Subject: RE: Velcade in early stages
Date: 01/09/2008

Apologies for an off-topic, but what does the following mean:

TitleMultiple Myeloma Patients: VELCADE, Thalidomide, and Dexamethasone Versus VELCADE and Dexamethasone Versus VELCADE, Melphalan, and Prednisone 
PhaseIII 
ModalityChemotherapy, Hormonal Therapy, Signal Transduction Inhibitor 
Sponsor TypePrivate

what are they actually testing: Velcade, Thalidomide and Dex, or Velcade and Dex? what actually is on trial here? My mother has had exactly what they say in description for 6 months, I am wondering could she be part of that trial without realising?

 

thank you

Yana

 

 

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