My name Is Tricia, My Mother Grace is 71 and has metastatic breast cancer. She is taking aromisin, with the side effects of depression, crying, feeling jittery. The doctors have tried three different antidepressants with no luck. They say the hormone therapy is not letting the antidepressant do its job. This is the third hormone drug, she tried arimidex and femara also. Has this happened to anyone? Our family is at a loss.