PSA Rise Post Radical Prostatectomy

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PSA Rise Post Radical Prostatectomy

by Debabrata on Sat Jun 02, 2007 12:00 AM

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I'm  going  to  be  72 yrs  in  August  this  year.  I  was  operated  for

Radical Prostatectomy on  2nd December 2005. My  doctor  was  very

happy  with  my  recovery  post  RP.  My  PSA  readings  were  as

follows : 3  mnths  after  ops  0.03

             6  mnths                 0.04

             10                          0.119

             13                          0.13

             17                          0.17

I feel top   on   of  the  world  with  no  symptoms, problems  and  no

shortage  of  energy   commensurate  with  my  age. I  exercise

regularly  and  try  to  have  Veg  diet  mainly. No  smoking  and

none   or  little  alcohol  intake.

My  Incontinence  is  almost   down   to   0.

I'd  like  to  find  out  if  the  PSA  rise  is  alarming. I'd  positively  like

to  avoid  any  Radiation  or  Chemo  at  any  cost, ever. Any  advice,

suggestions  or ideas ?

                                 With  regards  to  all.

                                                                Debu.

RE: PSA Rise Post Radical Prostatectomy

by Witchdoctor on Sat Jun 02, 2007 12:00 AM

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You have residual prostate cancer/tissue.  What to do depends on multiple factors including age, health and speed of the increase.  You can observe it and only treat it if it jumps higher suddenly or you can opt for local treatment hoping to knock off whatever is left.

RE: PSA Rise Post Radical Prostatectomy

by Johnw100 on Sat Jun 02, 2007 12:00 AM

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Some general pinions (of Dr Scardino for example) are, "A PSA that starts to rise within the first two years suggests distant metastases, while an increase that begins two years or more after RP points to local recurrence."

This is only a very general observation, and no one can immediately be 100% sure if it's local or not: no doubt your doctor would be considering your full situation, surgery lab report, margins Gleason etc.

Personally I'd be considering an early agressive approach: studies indicate a better prognosis with early therapy.

The books by Dr Charles Myers and Dr Lee Nelson both cover this topic. Both publications are worth reading. 

John

 

RE: PSA Rise Post Radical Prostatectomy

by Debabrata on Sun Jun 03, 2007 12:00 AM

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On 6/2/2007 Johnw100 wrote:

Some general pinions (of Dr Scardino for example) are, "A PSA that starts to rise within the first two years suggests distant metastases, while an increase that begins two years or more after RP points to local recurrence."

This is only a very general observation, and no one can immediately be 100% sure if it's local or not: no doubt your doctor would be considering your full situation, surgery lab report, margins Gleason etc.

Personally I'd be considering an early agressive approach: studies indicate a better prognosis with early therapy.

The books by Dr Charles Myers and Dr Lee Nelson both cover this topic. Both publications are worth reading. 

John

 


Dear  John,

Thanks  for  your  message.  Are  you,  by  any  chance,  a  survivor ?

I'd like  to  hear  from  one  who  has  had  the  problem  himself  and  how  it  is  being  tackeled . The  rate  of  PSA  rise  vis a  vis  the  actual figure  should, I  feel , to  be  monitered. I'd  like  to  find  if  there  is  any  scale  existing  in  this  subject.. I'm  visiting  my  Doctor  the  next  week  and  will  be    better  informed.

Regards.

Debu.   

 

.

RE: PSA Rise Post Radical Prostatectomy

by Debabrata on Sun Jun 03, 2007 12:00 AM

Quote | Reply

Thanx. Your   advice  is  noted.  A  careful  watch  is  being  maimtained.

Debu.

RE: PSA Rise Post Radical Prostatectomy

by Johnw100 on Sun Jun 03, 2007 12:00 AM

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It's correct that rate of PSA rise is an important consideration. Many consider that if the PSA doubling time is less than 10 months, consideration should be given to early treatment.

MSK have a number of nomograms and information on prognosis and relevance of PSA doubling time which could be discussed with your doctor.

Regards,

John

 

 

RE: PSA Rise Post Radical Prostatectomy

by Kenny_Bouy on Thu Jul 05, 2007 12:00 AM

Quote | Reply

 

On 6/2/2007 Debabrata wrote:

I'm  going  to  be  72 yrs  in  August  this  year.  I  was  operated  for

Radical Prostatectomy on  2nd December 2005. My  doctor  was  very

happy  with  my  recovery  post  RP.  My  PSA  readings  were  as

follows : 3  mnths  after  ops  0.03

             6  mnths                 0.04

             10                          0.119

             13                          0.13

             17                          0.17

I feel top   on   of  the  world  with  no  symptoms, problems  and  no

shortage  of  energy   commensurate  with  my  age. I  exercise

regularly  and  try  to  have  Veg  diet  mainly. No  smoking  and

none   or  little  alcohol  intake.

My  Incontinence  is  almost   down   to   0.

I'd  like  to  find  out  if  the  PSA  rise  is  alarming. I'd  positively  like

to  avoid  any  Radiation  or  Chemo  at  any  cost, ever. Any  advice,

suggestions  or ideas ?

                                 With  regards  to  all.

                                                                Debu.


 

Reply to: Eurofox2@aol.com..  Hope you are doing well..I'm 61..8 mo. ago I was diagnosed with T1, higher Gleason, immediately scheduled rp/nns which was done in Jan 07, 30 lymph neg., 1 seminal vesicle positive...what was your exact results of your surgery?...I am a lay applied technology type, have read & studied about all related....generally, in the first 2 yrs, post rp and there is a "detectable" psa, you need to pull out all the stops and make sure that you have competent medical observations and related work. There is always some "juice & stargazer" types offering advice but, in your case, you need to proceed as above. You may need hormone therapy..eventually chemo..directed radiation, etc.....keep the faith.... a reason that I am so certain is, in a way, I'm in your boat....waiting for psa results every 3 mo. seems like watching the fon in hopes the govenor will call to stop the execution....it grinds on my nerves & creates depression. However, I am blessed to have gotten a jump start by psa detection when digital was normal
and I had no symptoms...and I am so thankful its 2007 and not 1967..etc...Best wishes..

RE: PSA Rise Post Radical Prostatectomy

by doctork on Sat Feb 27, 2010 05:11 PM

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do not be afraid of radiation therapy... there are little side affects and  it is much better than chemo.

RE: PSA Rise Post Radical Prostatectomy

by worriedwifey on Mon Sep 20, 2010 01:51 PM

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my husbands psa has been rising steadily since his radical prostatectomy 4 years ago.  He is 62 and has now been told that he needs radiotherapy.  Why zap the prostate bed when the drs don't even know if the rogue cells are there.  Why is chemotherapy not used.

RE: PSA Rise Post Radical Prostatectomy

by phutzler on Sun Oct 03, 2010 05:12 AM

Quote | Reply

Kenny,

My story is very similar to yours, I am interested in what you are doing in regards to the positive seminal vesicle as my prognosis was the same. I just had robotic prostatectomy and thought that would be the end of it but I guess I was wrong.

Paul

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