Don't rule out interferon. Everyone has a different tolerance to the side effects. My oncologist told me to try to get through the first month of treatment -- which is high dose interferon administered 5 days per week intravenously. It was a really bad month -- but it was just ONE month. I slept through most of it and did experience nauseau, weight loss, skin rashes, fatigue, etc. However, you just keep counting down the days. It is only 4 weeks. At the end of 4 weeks, my oncologist told me that we should try the low dose interferon (3 shots per week) but if I experienced severe side effects we would stop the treatment. I still had side effects such as fatigue, metalic taste in my mouth, some hair loss, skin rashes -- but the nauseas subsided and compared to the first month it was easy. I just finished a year of treatment and I am glad I did it. I feel that I have done everything I can to prevent a recurrence. I suggest you try to get through one month of Interferon (high dose) because the first month is the most critical in reducing the risk of recurrence. I was out of work on disability for the month long treatment, but later returned to work full time and worked for the rest of the treatment. I am glad the treatment is over, but I am also glad I did it.