John - If you are under the impression that doctors are no longer using PSA to detect early stage prostate cancer, I think you are mistaken. PSA continues to be the best "marker" we have and will continue to be used. However, now they are talking about the PSA "velocity" as being most critical. In other words, how much has the PSA risen from one year to the next. PSA that rises 1.0 or more points in a year's time are likely to indicate aggressive cancers. So, any man who avoids getting his PSA checked annually (whether his doctor recommends it or not) is doing himself a tremendous disservice.