Women who don't have BRCA mutations could have other high-risk genes that affect treatment choices
by Carol65 on Fri Jun 29, 2007 12:00 AM
Hi, my name is Carol-- my mother-in-law was diagnosed with AML July 06--we did an experimental treatment here in Missouri at Barnes Jewish Hospital--called Decitabine. She responded for a short time, but now we are in hospice. I am asking for information on the end stage symptoms of AML-- she is 74yrs old. The blasts were 87% 2weeks ago in the hospital. She is at home and we(family) are taking care of her. She is progressively getting weaker. Now she is starting to vomit. She has a horrible canker sore inside her mouth(cheek)--we have been giving her oxycontin--for pain control. Just want to know how we will know when she is close the end of her days--its so hard to watch her get weaker and weaker. I do however know that someday she will be free of this horrible disease and be rejoicing in heaven
by ellenb on Mon Apr 06, 2009 12:00 AM
by jcr65566 on Mon Apr 06, 2009 12:00 AM
Hi Carol Im 57, and have prostrate cancer. Sorry for what your going through I had three of my very close family member go through this. I still miss them every day. I notice the nurse would gently pinch there skin I ask why, she told me to see if there dehydrated I even still talk to them some times. But when they died I felt like I died with them. I went though every emotion you could think of. They would tell you there going, then recover a bit, then tell you there going again. Over the years I heard of a lot of people have died where I live a lot were close friends. Most of them died a lone. My friend Jack was 78 took days to die. On the last night, he went back to his own room, up the hall, and died in his own bed. We still don’t know how he did this, as he was in the stage when he couldn’t even walk. All I can tell you watching a love one die is the most interment moment you will ever go though.
Can I ask you? All the treatment she had so far. Has just been chemo have you tried the Bidwig Diet here a report on it. Make realy good reading
Ive read that Decitabine belongs to the category of chemotherapy called antimetabolites. An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of the normal metabolism of a cell. Antimetabolites are very similar to normal substances within the cell. When the cells incorporate these substances into the cellular metabolism, they interact with a number of targets within the cell to produce a direct cytotoxic effect (cytotoxic is the quality of being toxic to cells.) so the cytotoxic effect can causes the death of rapidly dividing cancer cells. the problem with this is the cancer can adapt very quickly so after only a few weeks it can be comes nearly useless as a cancer fighter. God bless you both Ray
by mary110 on Sat Dec 26, 2009 06:53 PM
Hi,my name is Mary..my mom died from aml ,she could'nd fight with the infection. her infection was popping out and her fever was gone higher til 106..then she went into coma .She died on the 3rd day of coma .MAY GOD BLESS HER IN HEAVEN .
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