Women who don't have BRCA mutations could have other high-risk genes that affect treatment choices
by kiki5 on Fri Jul 20, 2007 12:00 AM
My dad has just been diagnosed with prostate cancer and my parents are being very sparing with information. Apparantly he was given 2 scores, one of over 50 and one of over 1,000 (not sure if they would both be PSA scores?). They are starting hormone therapy and not bothering to give him a biopsy or any scans. From what I've read I am presuming that it has already spread, but trying to get a grip on what his life expectancy may be.
Any guidance appreciated - i'm currently living abroad and now making plans to come home in the next few months but wondering if i should expediate this.
by Johnw100 on Fri Jul 20, 2007 12:00 AM
You need to look at dates and numbers of the PSA readings to gauge the situation.
No one knows in advance how effective hormone treatment will be: it is possible for it to reduce PSA levels to very low readings within the first 3 months and remain low for an extended time. In other instances it does not work as well, or becomes less effective.
A friend who started hormone treatment 18 months ago tolerated it well, he's currently travelling in Europe, and still plays golf . His PSA is 1.
For more information on hormone treatment, there are other previous posts here, you can also look at mentors experiences at the yananow site, or read Dr Myers publication.
by Island on Sat Jul 21, 2007 12:00 AM
Oh I am Mrs. Chaco again...jusat excuse the way I write. I write lkie I am talking tomyou in person. I ahve no time to edit my grammar. Thank you for your consideration.
by Kenny_Bouy on Sat Jul 21, 2007 12:00 AM
by Witchdoctor on Sat Jul 21, 2007 12:00 AM
I believe he needs to be staged and have at minimum a biopsy.
PSA is not a quantitative measure of tumor. The amount, if any at all, differs from cancer to cancer. Hence, you can have a relatively small amount of tumor either local or locoregional and a high PSA and/or a low PSA with distant mets. So it is worth establishing upfront the extent of the tumor since , for instance ,if it is just in the prostate and LN's it is possible to cure, or , some believe if you can cover the active sites of disease easily it my prolong the remission.
Gleason is important to establish the aggressiveness of the tumor and if metatstatic and high grade, may make the patient a candidatee for Chemo / hormonal therapy. (investigational) to try to treat the sensitive and resistant clone concurrently.
Staging can also identify potential problem areas that need to be addressed. ie impending fracture of bone or bloickage.
So ,even if widespread, it is of value to know what you are dealing with upfront and could effect treatment now or in the future.
by kiki5 on Sat Jul 21, 2007 12:00 AM
by sonsthree on Mon Jul 20, 2015 12:03 AM
We just found out my father has a PSA level of 62.11. Up from 52.89 six months ago. He is failry decent health and says he is in no pain at this time. The docotor does not think a biospy is worhth the risk at his age. He is 90 and a widower, has some memory issues. But all-in-all knows what is going on around him. He has chosen to take no course of action with any treatment.
From what I can see these levels indicate he is into stages III & IV, but I don't know. I am traveling to see his doctor and wanting as much information as I can get.
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