Ok, this is Shelby's regimen: Reglan 10 mg 3 30 min before each meal, L-Glutamine Powder 1 teaspoon mixed in food in the morning, C3 Curcumin Complex one in the morning with her food, Duralactin 1000 mg one with morning food and one with evening food, Probiotic Synergy one with morning food and one with evening food, Fish Oil 4000 mg a day. I use a pump and it is 4 pumps into each food bowl. Piroxicam one on Monday and one on Friday. Then after each meal we give her about a tablespoon and a half of greek yogurt with a tablespoon of Firm Up and the 2 cc of Neopleasene mixed in. That all. (thats a lot!). I tried giving her the neoplasene in a meatball but she did not like it. She laps it right up in the greek yogurt. At first I gave her plain yogurt because she is supposed to be on low carbs but then I switched to honey flavored or vanilla flavored. I figured it couldn't hurt her to have something that tasted better. She is on a grain free diet too. I looked into blue buffalo but it has oatmeal (I think) in it. So that's when we went to giving her rotisserie chickens from Costco. I pick a whole chicken into a ziplock and then add a can of french cut green beans and freeze it. I look like a nut checking out at Costco with 6 chickens in my cart! It is so much work to carry out this routine but we love her so much that we don't care. We started her on 1 cc twice a day too and then went up to 2cc after a month I think. I am hoping she can go back to 1cc soon. Our vet is looking into a maintanence dose for her. The only concern I have is that she still squats for a long period of time and urine comes out good at first and then begins to dribble. It takes her forever to pee. But the vet said she has a narrowing of her bladder wall and that is not going away. But the tumor is gone and it was pretty good size. Siena might be having some nausea. I would ask the vet about the Reglan. I think it helped Shelby not to get nauseated. Also, the greek yogurt would help and I don't think it would hurt. Ask your vet. Shelby weighs about 50 pounds so very close to Siena. Just be aware that it took Shelby 5 months before her tumor disappeared. We were happy that it was just staying the same size and really had no hope that it might disappear but when it did of course we were thrilled. And we had a biopsy so I know she did have tcc no question. Also, you are right to give her the Neoplasene last after she eats. It should not be given on an emply stomach. I'm sorry this is so long but I want to help anyone who is going through this if possible. I don't know if this could possibly work for anyone else. I only know it worked for us for now. Maybe it will come back..I don't know. I'm taking one day at a time right now. Yes, we are in Collierville, just outside of Memphis. Good luck to you and Siena. I pray for her recovery. By the way, how old is she??? Shelby is 13!!! She's a trooper though. A goldne retriever mix with a big heart! I wish I could post a picture on here of her sweet face. Let me know if you have any other questions!