Latest messages for CancerCompass discussion http://www.cancercompass.com/message-board/message/all,1543,0.htm Sat, 25 May 2013 00:00:00 GMT Sat, 25 May 2013 00:00:00 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ Hello everyone.  I haven't been on here since November.  I lost my little girl to this disease in October of last year.  My hear goes out to all of you who are going through this right now.  When Peaches was going thru this, I purchased something called Tinkle Trousers which is similar to the PeeKeeper, but for larger dogs.  I never was able to use these on Peaches, so I would be happy to give them to whoever can use them.  They are a size Meduim for 45-60 lb dog, gender female.  They are made so when she has accidents, they will catch it like a diaper, but it still gives her the freedom to have bowel movements.  I found the box while cleaning yesterday, and after a good cry, I wanted to do something good and help someone else out.  If anyone can use them, please let me know and I will send them to you at no cost.  Debbie MyPeaches Fri, 24 May 2013 00:00:00 GMT I am so absolutely thrilled with our good news. We have been celebrating with lots of walks and cuddles. I would like to Thank You all again and assure you all that I have every intention of making sure we move forward with lots of new knowledge and positive changes that will hopefully affect her health for the better. I already started making the changes necessary when I thought she had this awful disease and will continue to follow through with them. There is so much excellent info contained within these posts and so much good will, you should all be so proud of your efforts and the care you put towards others. All of your stories here and well wishes have affected our lives in such a positive way.  Alex has been on so many adventures with me over the past 10 years. I adopted her from a high kill shelter in LasVegas NV, on her last day at 18 months old, and we have been inseperable ever since. Shes been literally all over the US and Canada with me and my fiance. We include her in nearly everything we can. Shes my flower girl in my August wedding, and I am so very happy to know she will be there and wearing the flower girl collar that I made for her and she will be standing with us as we become a new family. She could not be more loved and appreciated than she is. I hope I have given her a wonderful life that is all she could have dreamed of and I plan to make sure each day with her is special. I updated my profile picture with a photo of her and my fiance running on the beach on Vancouver Island last summer, one of my favorites of her. I'm looking forward to whatever new adventures are in store for us this year, and every year she is with me. My best wishes and hopes go out to all of you. kristinrebecca Thu, 23 May 2013 00:00:00 GMT So very glad to hear this, I have prayed hard for both of you. I wish you the happiest of weddings and many days with Alex.  MinnieMo Thu, 23 May 2013 00:00:00 GMT Kristin and Alex, Best news I've heard for a long time.  There was only one other time (since I've been on CC) that someone got the "good news" of no TCC diagnosis.  Please be vigilant so if in the future something does go wrong, you will notice it immediately and take action. Go forth and be HAPPY! :-) ChicasMomForever, Lynn ChicasMom Thu, 23 May 2013 00:00:00 GMT Kathy, This is th first time that I got to get on the internet (we are on the road). I am sorry for your loss of Slice.  No amount of time with our furry little friends is enough.  Even the bad times we had with them was appreciated, and we still had them by our sides. "So sad, and so relieved"....I know what you mean.  At first I felt SO guilty that I felt relief.  I finally figured out that I was actually very relieved BECAUSE she would not have to suffer.  Knowing that does not actually make me feel any better, but, my mind can understand.  Now...my heart is another story. What a wonderful and thoughtful thing to do for your other pets, and absolutely not weird at all.  At least they will not have to wander around looking for him, finally figuring out that he will not be returning. I wish you and hubby the peace that you deserve.  You were good dog parents to Slice. Again, SO sorry. ChicasMomForever, Lynn    ChicasMom Thu, 23 May 2013 00:00:00 GMT Great news about Alex- broccoli treats for everyone. Kathy ( Slices mommy) slomokat Thu, 23 May 2013 00:00:00 GMT This is incredibly wonderful news! I'm so very pleased for you and Alex! Although I'm sure that you will, please keep up with a few preventative measures.  Apologies for getting 'all practical'! I'm sure all of us with dogs living with TCC, would have wished that we'd perhaps have been more aware before the diagnoses. Immune modulator:   such as a therapuetic dose of AHCC. Diet: let broccoli (or broccoli sprouts)be a constant addition to Alex's meals. Consider a low dose of salvestrols. Good quality multivit/multimineral. Filtered water! Avoiding as many chemicals as practicable, inc those that may have been used to treat lawns, etc. Exercise! Plenty of cuddles and kisses! Photos/videos! I appreciate that you've said: " I am taking with us into her future care to hopefully prevent her from getting this awful disease down the road." but I feel happier mentioning the above, rather than not! Good that you're doing a follow up urine culture, plus hopefully another urinalysis. I'm picturing Alex on your bed. Sleep's a wonderful thing :-) I'm glad we were able to offer whatever support, information and advice we could. Your very kind comments to everyone certainly mean a lot to me personally.  You take care and enjoy the rest of your lives together :-) Garry and Logan (UK) LogansDad Wed, 22 May 2013 00:00:00 GMT Dear Kathy I am so terribly sorry to hear about Slice.....but you did the right thing. 15 years together is such a long time, but it never seems long enough. Letting your other dogs see Slice after he'd passed, is a good idea. When we lose someone will love so much, it can be such an unusual mix of sorrow and relief. Slice is now running free in spirit, across the rainbow bridge...until you meet again. Take care, Kathy Garry and Logan (UK) LogansDad Wed, 22 May 2013 00:00:00 GMT Sorry Kathy, In my haste I said girl instead of boy. Apologies Deb & Andy tryeverything Wed, 22 May 2013 00:00:00 GMT Dear Kathy, So very sorry to hear the news of your dear girl. You are in all of our thoughts, hearts are breaking for you right now. Hope that it's not too long before you can think of her with laughter instead of tears for all the great times you both had. Time never fills the void but it does help to fade the pain & heartache of loss. Deb & Andy tryeverything Wed, 22 May 2013 00:00:00 GMT Thanks for sharing this wonderful news. At least you will be tuned in & very vigilant. Just wonderful! Deb & Andy tryeverything Wed, 22 May 2013 00:00:00 GMT Kristin, That's WONDERFUL news!! I am so happy for you guys. I was almost afraid to check back here because I was convinced she didn't have it and was hoping I didn't jinx it. Her symtoms were nothing like Lizzie's. I was hoping Alex just had a UTI. It's AMAZING and I am so happy you will be able to enjoy your wedding. HUGS to you and Alex!! LizziesMommy Wed, 22 May 2013 00:00:00 GMT After a very long day at the teaching vet school we are home and I have amazing, wonderful news that I was not expecting. Despite what 3 different vet clinics and vets told me (I spent the last 4 days on the phone with different clinics and vets trying to get opinions on what to do and what this all meant), after more urine tests, blood tests and ultrasounds, Alex shows no current signs of bladder cancer. The transitional cells that appeared during her UTI have cleared her system. They believe they occurred after a long bout with a low grade UTI that finally showed itself by getting bad enough for me to see the signs. They believe the prolonged inflammation in her bladder caused the cells to shed. The vet there said I was right to be concerned....shes at a perfect age to get bladder cancer and transitional cells in the urine are not generally a good sign. Shes got some protein in her urine but we will watch that with a follow up urine culture in another month. It may be caused by residual inflammation. If she continues to get UTIs we will go back for further testing, but the vet seemed fairly confident she will be ok. It was an expensive, exhausting day, but the best possible outcome I could have ever hoped for. And I had very little hope going into this. I want to Thank You all for your support and suggestions, and there are things I learned here about immune support and food/water I am taking with us into her future care to hopefully prevent her from getting this awful disease down the road. You are all an amazing support network and have touched my heart with your stories and strength. Alex and I Thank you all so much for your concerns and hopes. Alex is laying on top of all the pillows on my bed currently and snoring away after her rough day. I know there are so many on here not as lucky, and I can only say that having seen things through your eyes and having come close to being in your shoes I have tremendous respect for all your fortitude and resilience. I can only hope to be as strong as you all when the time comes that I have to part with my best friend. My heart goes out to you all. kristinrebecca Wed, 22 May 2013 00:00:00 GMT Thank you to everyone for the kind thoughts. I really miss my guy, and even miss taking 24 hour care of him- I guess I just got use to it. 15 years by your side, following you room to room, is just so hard to live without.  I keep looking for him. Again, I have many pills, needles, POISE pad ( works wonders), belly bands, pampers wipes, and more...if anyone is in need. Kathy - Slices' forever mom. slomokat Wed, 22 May 2013 00:00:00 GMT So very sorry to hear this. When you described what was happening, I knew exactly how you were feeling as we went through this in August.  Sadly we only had Sadie for 7 years and it is never enough time, regardless. Hugs to you.  MinnieMo Wed, 22 May 2013 00:00:00 GMT On May 20, 2013 6:43 PM MinnieMo wrote: It takes as long as it takes. For me we lost Sadie in August and I am still not over it. I am better and I have really good days and some not so good days.  She was family, she was my dearest and closest friend. We went everywhere together.  Like you, I had dogs all my life, but never did one capture my heart like Sadie did.  At this point I am not sure I will get another dog. I have lost one child in my life and then Sadie, I can't do this again.  Hugs to you Holly MinnieMo, I'm so sorry for your losses :-( I agree that the loss of Lizzie first made me say I couldn't do it again...have my heart broken like that but I am on a Wheaten Terrier Facebook Page and seeing the sweet little girls that look like Lizzie make me want another one in my life. I can't do anything as long as my dear Frizzy is with us (he doesn't like other dogs) but I will do it again. I am so lonely in my house. A part of me is missing. Maybe one day you'll be able to change your mind. The loss is so hard, but the joy they give us when they are here is unbelievably wonderful. {{{{{{Hugs to you}}}}} LizziesMommy Tue, 21 May 2013 00:00:00 GMT Hi Kathy-- I am so very sorry to hear of Slice's passing...it brings tears to my eyes.  TCC is such an awful disease...it's not fair that our beautiful furry companions have to go through this. Try to remember all the good times and know that you did all you could for Slice.  No matter how long they are with us, it's never enough.  My deepest sympathies are with you. Karin Baileysmom97 Tue, 21 May 2013 00:00:00 GMT Kathy, Perhaps Slice still wanted to say goodbye to you and was hanging in there for your return.  I'm glad you got that chance to be there for him, and that he was alert/conscious of you, even if he was suffering!  The vomiting and seizures you described for Slice (I guess kidney and or heart failure) I dreaded for Meg, so I made the horrible decision to put her to put her to sleep before such episodes.  I miss her so much, and I expect to for years to come. I can sense both shock and relief in what you wrote and sorry too. Slice had 15 good years -- be glad for them and him. Sorry, I'm crying too, so I'll sign off. Cathy      Cathtalk Tue, 21 May 2013 00:00:00 GMT On May 20, 2013 10:14 PM kristinrebecca wrote: Gary are you of the opinion that the AHCC and K9Immunity Plus are about the same? Am I understanding correctly that they both have the mushroom ingredients? I'm looking into the Salvestrols as well. I want to make these dietary changes a little slowly and not upset her system, so if something doesn't agree with her I will know what it is and can back off.  Alex has to fast starting at midnight and then we make the 2.5 hour journey to Madison for her appt. tomorrow morning. I'm so afraid of what they will find. I will let you all know where we stand Tuesday nite or Wednesday. I'm not sure what shape I will be in. Thank you everyone whos been following us for your hopes and kind words for us. We can use all the good thoughts and hopes we can get right now. Kristin, I have been praying for you and Alex. I am hoping you come back to this board with good news about Alex. It sounds like you are taking her to a great place and she'll have great care. As others stated, even if she does have the diagnosis, she can live years. In Lizzie's case, she had it in the worst possible place. It doesn't sound like Alex has the same symtoms. Sending prayers and {{{{{Positive Vibes}}}}} that everything will be ok. Please keep us posted. {{{{{Hugs}}}}} Holly LizziesMommy Tue, 21 May 2013 00:00:00 GMT On May 21, 2013 11:32 AM slomokat wrote: Slice is gone. We took him to the vet after his third ( and worst ) seizure. He was breathing, and sort of responsive, but it was his time. It was either put him down or go through battery of tests.  I felt he had enough and it was time to say goodbye. I find it hard to write or even speak at this point.  My buddy and sidelick for 15years is gone. We brought him home so the other 4 dogs could sniff him and see that he is gone ( not sure if that is weird or not).  Taking him to be creamated when they open. So sad, and so relived.   I miss my baby Slice.  Thanks for all the support and I wish you all the best. I have supplies- diapers, meds, pee pads. If anyone is in need. Many thanks, Slice and Kathy- Las Vegas OMG Kathy, I am so so so sorry. I know how you feel and there are no words that can comfort you. It does get a wee bit easier every day...just a wee bit. Slice was so lucky to have you as a mommy. I am in tears now because I hate to see people go through what I am going through. Now I am wondering if we should have let the other 2 dogs say goodbye after Lizzie was gone. She is buried in our back yard. I don't think it's weird. You did what you feel is best. {{{{{Big Hugs}}}}} to you and my deepest condolences. RIP Slice Holly   LizziesMommy Tue, 21 May 2013 00:00:00 GMT I'm so very sorry for your loss Kathy.  I was very saddened to see your news this morning.  My heart goes out to you. kristinrebecca Tue, 21 May 2013 00:00:00 GMT Slice is gone. We took him to the vet after his third ( and worst ) seizure. He was breathing, and sort of responsive, but it was his time. It was either put him down or go through battery of tests.  I felt he had enough and it was time to say goodbye. I find it hard to write or even speak at this point.  My buddy and sidelick for 15years is gone. We brought him home so the other 4 dogs could sniff him and see that he is gone ( not sure if that is weird or not).  Taking him to be creamated when they open. So sad, and so relived.   I miss my baby Slice.  Thanks for all the support and I wish you all the best. I have supplies- diapers, meds, pee pads. If anyone is in need. Many thanks, Slice and Kathy- Las Vegas slomokat Tue, 21 May 2013 00:00:00 GMT Previous experience with seizures? Sadly yes, on the day Sadie died she had a seizure and never responded to any of us after it. She was still breathing but the Vet said her heart beat was very weak. She also threw up that morning.  We let her go.  MinnieMo Tue, 21 May 2013 00:00:00 GMT On May 20, 2013 10:14 PM kristinrebecca wrote: Gary are you of the opinion that the AHCC and K9Immunity Plus are about the same? Am I understanding correctly that they both have the mushroom ingredients? I'm looking into the Salvestrols as well. I want to make these dietary changes a little slowly and not upset her system, so if something doesn't agree with her I will know what it is and can back off.  Alex has to fast starting at midnight and then we make the 2.5 hour journey to Madison for her appt. tomorrow morning. I'm so afraid of what they will find. I will let you all know where we stand Tuesday nite or Wednesday. I'm not sure what shape I will be in. Thank you everyone whos been following us for your hopes and kind words for us. We can use all the good thoughts and hopes we can get right now. Best of luck with Alex's visit to the vet. Slice and Kathy slomokat Tue, 21 May 2013 00:00:00 GMT It seems Slice had two seizures today ( i have been gone for four days and the husband  gave positive reports on Slices condidtion until today). Then the vomiting started.  The husband said he thought he had lost Slice. Miraculously, Slice was alert when I got home but could not get up.  He was covered in vomit, so I bathed him, and gave him some fluids. ( husband had to leave him to pick me up at the airport).  His is able to stand but seems week and out of it. He did eat a treat, some Hagen daas and I forced a Cernenia pill down his thoat. Hope tomorrow bring a better days for my baby. Suggestions?  Previous experience with seizures? slomokat Tue, 21 May 2013 00:00:00 GMT Hi Kristin, I will be thinking about Alex and you tomorrow.  I pray that you will get the answers that you need to help her. Don't give up hope or become discouraged, even if it seems to be bad news.  In most cases of TCC, it can be managed.  Chica was one of the lucky ones and we managed her disease for three years, five months.  Was it easy...no.  Was it worth it...a million times YES.  I know we were extremely fortunate to be able to take care of Chica's needs as they arose. Keep positive, keep strong and healthy.  Alex will need you. ChicasMomForever, Lynn     ChicasMom Mon, 20 May 2013 00:00:00 GMT Gary are you of the opinion that the AHCC and K9Immunity Plus are about the same? Am I understanding correctly that they both have the mushroom ingredients? I'm looking into the Salvestrols as well. I want to make these dietary changes a little slowly and not upset her system, so if something doesn't agree with her I will know what it is and can back off.  Alex has to fast starting at midnight and then we make the 2.5 hour journey to Madison for her appt. tomorrow morning. I'm so afraid of what they will find. I will let you all know where we stand Tuesday nite or Wednesday. I'm not sure what shape I will be in. Thank you everyone whos been following us for your hopes and kind words for us. We can use all the good thoughts and hopes we can get right now.  kristinrebecca Mon, 20 May 2013 00:00:00 GMT It takes as long as it takes. For me we lost Sadie in August and I am still not over it. I am better and I have really good days and some not so good days.  She was family, she was my dearest and closest friend. We went everywhere together.  Like you, I had dogs all my life, but never did one capture my heart like Sadie did.  At this point I am not sure I will get another dog. I have lost one child in my life and then Sadie, I can't do this again.  Hugs to you Holly MinnieMo Mon, 20 May 2013 00:00:00 GMT Unfortunately,friends and family won't always understand the real grief you are experiencing, Holly. Do you have any friends that might be more empathetic? Great that you were able to get out.  Lizzie would never wish you not to be able to get on with your life, even though she was such a huge part of it. Maybe not being able to get another Wheaten girl is fate. I'm not saying it's the case with you, but some people do rush to get another dog when they are still grieving and sometimes this just doesn't work. No doubt, it may work for some - but not all. Maybe you will start to develop a new relationship with the boys, who will no doubt realise things have changed. Yes, we're so very pleased that Logan is still with us. As Andy has said, you can become almost paranoid over issues such as weeing.  I watch every single time he wees - day or night (thankfully, he doesn't get up to go the garden during the night that often). And we also hope that our boy will just reach a stage when he will leave us through normal old age - whatever that is?! I'm praying that's a way off yet. Keep strong Garry and Logan LogansDad Mon, 20 May 2013 00:00:00 GMT Thanks Holly, yes we are blessed to have 12mths but hoping that old age will determine his passing instead of this wicked disease. I hope you are going ok & the days ahead will become a bit easier on your heart. You never stop stressing even after a year has gone by my heart stops a beat if see him fussing about in the back yard doing wees. It's probably what he's always done but my paranoia kicks in. I guess this will be life from now on. I don't even stop him from barking at everything that passes by - it means he is still with me (poor neighbours) Deb & Andy tryeverything Mon, 20 May 2013 00:00:00 GMT I've added responses below in italics :-) Gary do you have Logan on any traditional meds now that you've stopped chemo? Or are you using just alternative? No traditional meds for TCC. Do you track progress with ultrasounds ocassionally? Last u/scan Feb. Had ct scan too. Thoracic x-rays earlier in year.  undecided re further u/scans.  Logan found being placed on his side for scans, quite stressful.  he found the whole process of visiting the clinic very stressful. this was also part of reason for not continuing with iv chemo. We keep a very close eye open for symptoms (diff weeing, blood in wee, etc.) Do you feel his symptoms have improved with what you are doing? Although Logan tolerated most of the chemo sessions quite well, aprt from the occasional bout of nausea/vomiting, he once had a higher than normal dose of the chemo drug (although still lower than normal dosage for this drug) and from then on, he just 'wasn't well'.  He became more and more inappetant, a little lethargic, lost weight - a catalogue of symptoms. We were in contact with the oncologist, who originally felt it wasn't due to the chemo (given at previous clinic) given that it was then some 3 weeks after.  However, we became increasingly convinced that it was the chemo that was having this debilitating effect on him. We felt, following 2 further (lower) doses that it was just adding to the problem. Then we decided to consider metronomic chemo - giving daily oral chemo (which I discovered was carcinogenic!!), but this relied upon being given with a NSAID and our poor boy had side effects from this and the stomach protectant he had to have to protect his tummy from the NSAID! At that point, we decided, enough was enough.   I'd read about salvestrols (after being in contact with someone whose dog was receiving this (Deb with Andy - thanks Deb!)and was diagnosed same time as Logan , never having used chemo- never heard of salvestrols before and I thought that I was quite 'well read' on supps!)and AHCC and the science looked convincing to me, so we went down that road. We also changed him to a raw diet. He certainly feels a heck of a lot better (behaviour, appetite, general demeanour) since stopping the chemo, starting AHCC, salvestrols and being on a raw diet.  Prior to this, he was getting so unwell we weren't sure where it was leading - even our regular vet was not optimistic.  When she saw him the other day she was so impressed with how he presenting! It would be difficult to prove which has had the most impact. However, we are now 2 months from the last chemo, so I do believe that regular raw meals, coupled with the AHCC and salvestrols have made a huge difference. AHCC, as an immune modulator, can increase energy levls quite noticeably,quite quickly - so that's something 'tangible'. I cannot definitely guarantee that the salvestrols are working, but I do believe they are...the last urinalysis results (we have them done monthly, along with bloods) revealed no blood (apart from very few white blood cells). Neither I or our regular vet can recall ever seeing this in recent times - I looked at results back to mid 2011 and blood was always present. Although the oncologist would prob draw other conclusions to this (and no doubt other conclusions could be drawn)my gut instinct is telling me something's changed. I don't want to jinx it (now there's superstition for you!) by saying exactly what I mean!  also, his protein creatinine levels in urine have never been so low (still outside normal range, but vastly improved). Our reg vet couldn't believe this and had to speak with one of the clinic's senior vets who was equally impressed. Our vet phoned me to give the 'good news'.The internal med vet (during Feb) felt that the then high protein creatinine was largely to do with TCC rather than due to chronic kidney problems. Can I ask what symtpoms he does have and where he is at medically at this point into your fight? I hope hes doing really well. No apparent symptoms from TCC. A couple of months back (before AHCC, sals, etc.), when he was really unwell, he went through a bout of very bloody urine, difficulty urinating, passing a blood clot. We don't have this now. Prior to this, we'd ony seen blood on a few occasions during the previous 10 months. We were v concerned at that stage. Medically...prob the previous response above covers this in the main. Logan is doing very well.  He's a complicated dog and there will always be something going on with him, but we feel very confident with how things are going. The only symptom Alex has right now is licking after she goes to the bathroom and licking her abdomen area now and then. So I may not see anything change. I did order the AHCC and will get some DHA today. I do hope that you get good news next Tuesday. You did ask in a previous post about the various diagnostics involved - anyhting to avoid, etc.  all I would say, is to avoid anything that may be too invasive. I would not personally have any biopsies taken from her bladder - too much risk of (metastasis) spread of cancer cells. They may need to take their own bloods, carry out contrast imaging, etc. AHCC is a good supp and I really hope you'll see some positive effects with this. Good re omega 3s, too... Keep us posted Garry and Logan LogansDad Sun, 19 May 2013 00:00:00 GMT Thanks guys! I knew you would understand. Even my son (18) is getting annoyed with me. Last night, I told him that he can NEVER dictate how long a person can grieve, whether it be for a pet or person. I was able to get out for most of the day yesterday and I actually felt much better. I think the key is getting out of the house. The first few days, I felt guilty about leaving and even sleeping. I had no plans on ever taking Lizzie back to the doctor. I may have if her tumor was located in a different spot. But after the stress she went through at the vet's offices, I saw no need to put her through that. Gary and Andy's mom, you are so blessed to have had a year with your babies. Praying you get another year. I have 2 other dogs but it's like I have none. Lizzie was the queen of my house. I don't have anyone to snuggle with anymore. I can't even get another female wheaten (which is what I want) because my male wheaten is dog aggressive. Kristin, I am praying for positive news for Alex on Tues. Please keep us posted, Holly <3 LizziesMommy Sun, 19 May 2013 00:00:00 GMT Andy has been living with TCC for just on 12mths now, once he was diagnosed I have never had another trip to the Vets & have never had him on anything but alternative supplements. Over the time I have changed from this to that depending on what I have been reading. I immediately put him on raw meat with all the cancer fighting v-gs mixed in with cooked chicken & the broth with each meal. For the last few months I haven't changed a thing because he seems to be doing so well on the protocol I have him on. Maybe if he's looking like he's starting to become distressed I'll definately get the ultrasound. There are no holistic vets in my town which is great pity. tryeverything Sun, 19 May 2013 00:00:00 GMT Great question from kristinrebecca..... Does everyone get repeated Ultrasounds to see if the meds/supplements are working? Or, are you going solely relying on the way the dog is acting? Thanks, Kathy and Slice slomokat Sat, 18 May 2013 00:00:00 GMT You take your time grieving, your heart has been broken, allow it time to heal. I so feel for you. karincam1 Sat, 18 May 2013 00:00:00 GMT Hi Holly, You know.....you don't have to go back to the "candle site" to light a candle for Lizzie.  I picked up "flameless tea lights" from Bed Bath & Beyond (they last about 72-75 hrs.) and when the one burning seems to be going dim...I just light a new one. Some might think it weird, but when I look over at the light flickering next to Chica's ashes (in her little tan box) I can almost feel her still with me...it comforts me. Everyone grieves differently.  Your hubby did indeed love Lizzie...BUT...we women grieve from somewhere deep inside us.  It's like a physical hurt that I cannot fully describe...it starts out as a cold, numb feeling deep inside me and just overcomes my whole body.  Your hubby is probably right...it may very well be able to make you (me, us) sick. When we get the "snap out of it...making yourself sick" speech (yes, I have gotten it too), they never tell us HOW to do this.  At least hubby didn't give you the "JUST a dog" speech.  I almost smacked one of my neighbors in the chops for that one. You are not alone!  We'll just have to muddle through this the best we can and HOPE we come out of it stronger.  Your real friends understand and will listen when you have to talk...no matter what you say...they know that you need an outlet.  The others just don't understand...yet. I wish you peace of mind and heart, hopefully I will find that too. ChicasMomForever, Lynn     ChicasMom Sat, 18 May 2013 00:00:00 GMT Holly I want you to know I understand your feelings of shes not "just a dog" to you. My Alex has never been just a dog to me either. Her and I have had a bond of some magical kind since we both saw each other at the shelter 10 years ago. She hasn't left my side since. I can't even use the bathroom without her there. She sleeps with me at night and waits for me when I have to be gone and is a part of who I am as a person. We have a love for each other that is not just dog and owner. Shes added so much to my life that I can't remember what it was to be without her. I'm so sorry you are going through this. I do understand. My heart aches for you.  Thank you for your kind words and hopes for Alex and I.  Kristin kristinrebecca Sat, 18 May 2013 00:00:00 GMT Karin and Lynn, It was my pleasure lighting candles for Bailey and Chica. You are both grieving like I am. It meant a lot when Garry lit the candle for Lizzie and I wanted to do the same for you. When I am up to it, I am going to read back and light some for others. The only bad part is that the candles burn out. I lit another one for Lizzie yesterday. I miss her so so much. It has been 4 days and I can't stop crying, I spent 24/7 of the last 6 weeks caring for her. She was always with me. Now I feel alone. My other 2 dogs have been useless in the "best friend" department. I realize that they are grieving too. Yesterday, I got the "I loved her too but she was a dog. You need to snap out of it. You're making yourself sick." speech from my husband. I am sure my friends are sick of hearing me whine. I feel so alone. I am happy to have you guys on this board. <3 <3 LizziesMommy Sat, 18 May 2013 00:00:00 GMT On May 18, 2013 1:36 PM kristinrebecca wrote: Gary do you have Logan on any traditional meds now that you've stopped chemo? Or are you using just alternative? Do you track progress with ultrasounds ocassionally? Do you feel his symptoms have improved with what you are doing? Can I ask what symtpoms he does have and where he is at medically at this point into your fight? I hope hes doing really well. The only symptom Alex has right now is licking after she goes to the bathroom and licking her abdomen area now and then. So I may not see anything change. I did order the AHCC and will get some DHA today.Kristin, Lizzie NEVER had a UTI before and when she was treated for a UTI and when she was treated for 2 weeks before her testing on 2 different antibiotics, she NEVER inproved at all. In fact, she got worse. As for cost, between going to my original vet for bloodwork, urinanalysis, x-ray and then ultrasound and the specialist for the rest, the cost was around 1300.00. The sprecialist gave me an estimate of between 400-600, depending on anesthesia, meds, etc. Of course it was 600.00 because Lizzie fought them and needed general. If they do an ultrasound and don't see a tumor or "mass", they probably won't need to biopsy but don't quote me on that. I never heard of cystitis on a dog. If they do see something, just make sure they don't do any kind of biopsy where they have to stab at or disturb the tumor. They used water or something to suck the cells out without disturbing the tumor. Also, I was told that surgery wasn't an option. Lizzie's tumor was on the neck or her urethra, which is why she wasn't able to pee. If it was in a different area, she would have had more time. I am not trying to give you false hope but she may not have TCC. I am hoping and praying you for and Alex. Praying your wedding day is a beautiful day with a healthy ring bearer <3. Big hugs!! xoxo Holly LizziesMommy Sat, 18 May 2013 00:00:00 GMT Gary do you have Logan on any traditional meds now that you've stopped chemo? Or are you using just alternative? Do you track progress with ultrasounds ocassionally? Do you feel his symptoms have improved with what you are doing? Can I ask what symtpoms he does have and where he is at medically at this point into your fight? I hope hes doing really well. The only symptom Alex has right now is licking after she goes to the bathroom and licking her abdomen area now and then. So I may not see anything change. I did order the AHCC and will get some DHA today. kristinrebecca Sat, 18 May 2013 00:00:00 GMT agree with baileysmom, that looking after Alex's immune system is vital.  AHCC is an excellent immune modulator - giving it a boost when it needs it, but not otherwise. LogansDad Sat, 18 May 2013 00:00:00 GMT Re Salvestrols Really sorry that they didn't appear to work for Bailey.  Like with any supplement there's never any guarantee they will - i do realise that you're already aware of that.   there are certain things that can enhance salvestrols (vit C, good multivit etc. - things to avoid (B17), too.  also, an incresaed dose may be needed.  Dogs metabolise sals quicker than humans (like with many supps) and this should be taken into consideration too.   sorry this is brief. garry and Logan(UK) LogansDad Sat, 18 May 2013 00:00:00 GMT Sorry, link to omega 3 oild didn't work for me.   Here's the omega 3 fish oil we use:  http://www.thorne.com/Products/Essential-Fatty-Acids/prd~SP6 we try to use supps which don't contain too many 'unecessary' ingredients, expecially those we're uncertain about.  This oil is contained in fish gelatin caps, rather than beef gelatin. As for broccoli.  Yes, agree that it should be very lightly steamed (couple mins), although you can always puree raw and give that way.  Logan has raw broc, but he chews it so much it's just like puree! cauli, yes too,as it's a cruciferous veg - great veg for dogs with bladder cancer.  however, not too much of either, otherwise you'll run risk of upset tums. as for quantities, I'd stick to more more than around 15% of veg for total meal.  Salvestrols and B17...  Laetrile otherwise known as vit B17 is sometimes promoted as a 'cure' for cancer. It's mainly found in apricot kernels, but is also found in flax seeds. It's not really a vitamin (some would argue that it isn;t a vit, but that's another story...) that you'd need to worry about when feeding dogs, as it isn't something you'd normally include in their diet.  As for using flax seed oil, in the Budwig diet or otherwise, there are different schools of thought as to whether flax seed oil can actually be bioavailable when used with dogs. I have always erred on the side of caution and never used it for this reason.  however, there are those that use with their dogs and find it OK. Fish or krill-based omega 3s are far superior, in my opinion. Tolerating AHCC and salvestrols.  I found no problem at all with AHCC (and Logan can be quite a sensitive chap).  the first thing you may notice is higher energy levels.  As for salvestrols, if the dose is too high, it may cause some tummy upset - loose stools.  That's why I always advise not starting on a huge dose (some sites will recommend a loading dose (higher starting dose) for humans - not something I'd recommend for dogs).  At the recommended starting dose of around 1000 pt caps per 40lbs weight, twice daily, shou,d be no probs. If Alex is sensitive when it comes to new supps, yyou could start at half a 1000 point cap, twice daily, with food. Please don't aplogise for asking questions - you ask away.    I can't always respond as soon a s I'd prefer, but there are some good people on this forum, who will also help. Garry and Logan LogansDad Sat, 18 May 2013 00:00:00 GMT I have an appt. at a teaching hositpal in Madison, about 2.5 hours from here, on Tuesday at noon for Alex. The other vet we contacted who used to work at this teaching hospital said theres a possibility it could be a deep ulcerative cystitis which could also cause the cells. He recommended I see someone at this teaching hosital in internal medicine. After talking to the woman there she said the likely cost for that day will range from $800-$1200 to do diagnostics. Bloodwork, ultrasounds, xrays, whatever else might need to be done I guess. They will give me an estimate though for other work. Does this sound about average for diagnostics? I had no idea to start with what the cost might be. That leaves me with precious little money to treat her with. I will dip into credit cards at that point I guess and see what I can sell off. What do I NOT want them to do?....certain kinds of biopsies? Can anyone give me some idea of what to say No to, whats not advised? I don't want to torture her...shes scared of people she doesn't know as it is...shes been a scared dog since I got her 10.5 years ago... shes afraid of alot though has come around some on alot of issues. Thanks for the broccoli info, I haven't been steaming but maybe thats best? I just don't want to give her thawed from frozen if its somehow bad for her. She certainly eats it and no strange pooping issues yet. kristinrebecca Fri, 17 May 2013 00:00:00 GMT Hi Kristin-- Just saw your message.  I gave Bailey steamed broccoli and I was also told that fish oil was best, however because she didn't care for the taste, I gave her flax oil or even ground flax seed mixed with her food.  Bailey was also on Salvestrols for a few months, but they didn't seem to have any effect on her tumor.  They cost about $100 a bottle so I didn't feel it was worth it, but she had no problem taking them.  I just opened the capsule and mixed it right in with her food.  Looking back on Bailey's journey, I would try to boost the immune system.  As we got closer to the end, she developed some sort of infection which caused her to lose weight and it was very difficult to get her to eat enough and thus get all the supplements in.  I think she was more prone to the infection because of all the antibiotics which just killed the immune system.  Hope this helps you.  Good luck. Baileysmom97 Fri, 17 May 2013 00:00:00 GMT First to Holly, thank you so much for lighting a candle for Bailey.  Knowing that you're going through your own grief and thinking of others means a lot to me. Regarding Alex, I would try to find a veterinary hospital to recheck the cells in the urine.  Transitional cells make up the bladder so just because they are in the urine does not mean she has TCC.  They should be able to look at those cells under a microscope and determine whether or not they have TCC characteristics.  This is what they did with Bailey...they were able to spin the urine, collect the cells and then determine that they had a cancerous appearance. A veterinary hospital should be able to do this in their own lab or if you're lucky enough to have a teaching hospital around.  Then, it would be appropriate to go for the ultrasound to see where the mass is. Baileysmom97 Fri, 17 May 2013 00:00:00 GMT Thank you Gary & Logan and Deb & Andy for all your info. I'm going to look into those today. I've got calls in to my vet clinic and a regular vet I trust there to ask some questions about seeing a specialist and also an email in to a friend of my dads who has a position of some kind at a Vet teaching hospital in Madison asking for advice too. Can anyone tell me the right way I should be feeding broccoli and cauliflower? Raw? Steamed? Microwaved in the bag...whats best? I've been buying frozen and thawing it in the fridge and she will eat that no problem. Is spinach still considered helpful? How do I use it...raw, cooked? I want her to get the benefit of eating it but am not sure what way is best. How much should she be eating daily? If I go with the Salvestrols how do I know what else contains B17 to avoid giving her? I've never even heard of B17 before. I've heard Chia oil is also good in place of flax? Did your dogs tolerate AHCC and the Salvestrols well when starting off? Does this look ok for a DHA/Omega3 supplement?: http://www.gnc.com/product/index.jsp?productId=2133397  is there something better I should be using? I was hoping to get this bought today. Shes gotten regular fish oil over the last few years but its never very high in DHA..I was giving it for her coat and general health, not TCC though. I want to Thank you all for your advice and help as I try to get through this. I'm so sorry we are all here. I apologize for having so many questions. I feel like I am in a race to help her as fast as possible while we are waiting to get her in to see someone. Kristin & Alex (The vet just called back as I was typing this- he said they have someone who does ultrasounds and I could get her in right away and not wait if I wanted for a urinalysis that they would send it away for determination of the cells and I would get it back in a couple days. I will start calling other clinics in the area to see if they have oncologists they refer to or on staff. The vet I spoke to didn't really grab onto my wanting to see a specialist so I'm not sure what that means.) kristinrebecca Fri, 17 May 2013 00:00:00 GMT You are not alone.  All of us we're probably filled with dread, when we received a TCC diagnosis for our dog, or believed one was imminent. Vets (inc oncologists) may talk about 'median survival rates', the aggressive nature of this type of cancer and offer you either chemotherapy, or in some instances, radiation or even surgery.  Sometimes all of this information can be a little overwhelming or daunting given the emotional stress we're under at the time. However, please hang on to the fact that more dogs do live and have good quality of life way beyond the survival rates given. Also, you've read through the posts and will therefore see that there is more that can be done apart from the conventional offerings of chemo, etc. If not already, please see a board registered oncologist to carry out further diagnositics - general vets are not able to do this, or may not have the level of experience necessary. We did opt for chemo for Logan over many months, but have recently decided to go along a different path.  Once you've thought about the various options, you can then make your decision for Alex.  Everyone on the forum will have their own story to tell and their own set of circumstances to share with you. Some people may solely follow a more orthodox approach, some may purely opt for a more natural or holistic approach and some a mixture of each.  Whatever you decide, it will be right for you and no one will coerce you into going one way or another. Always feel free to ask for further info or advice. Personally, I'm not a vet, but I've been reading about TCC and the multitude of supplements and new drugs on the horizon, since soon after Logan was diagnosed on 1st May 2012. You did ask about AHCC and salvestrols and the doses for  Alex.    The salvestrols distributor for North America is in Canada:http://www.salvestrol.ca/index.asp        I personally use the Kinoko Gold AHCC by Quality of Life labs.  They seem to be the manufacturer upon which a lot of the research has been carried out. As for dosage.  AHCC -   For a dog Alex's size (48lbs), I'd suggest 2,000mg daily, split into two doses of 2 x 500 mg capsules. Give before (around 60 mins) meals or after meals (around 2 hours). This dose is taken from a study with dogs, which revealed the increase in Natural Killer cells using AHCC (either 50mg/kg or 100mg/kg - I'm basing on 100mg/kg - Alex being approx 20kg).  If you were to use AHCC, you would not necessarily need the K9 Immunity Plus (+, I believe this particular product contains sugar of some description(?) which should be avoided in dogs living with cancer) .  AHCC's molecular weight is many times lower than other mushroom extracts and therefore can get to work far more efficiently. Salvestrols.  The Canadian co. stock the 1000 point Platinum capsules.     I'd suggest one, 1000 pt cap, twice daily, with meals. Giving with meals increases the body's ability to use the salvestrols.  If Alex tolerates this does, I'd consider increasing after a week, to two, 1000 pt caps, twice daily.  If I had to recommend only two supplements, I'd have no hesitation in going for AHCC and salvestrols.Howeve r, it wouldn't be compatible with the Budwig diet using flax oil.  Salvestrols cannot work when vitamin B17 is used - flax contains B17. Yes, keep filtering her water!  we've just fitted a reverse osmosis water filter, after using a jug filter for many months. Yes, low/no grain food, good quality protein essential for dogs living with cancer, unless there are any other health conditions that would dictate otherwise. Broccoli is first class for those with bladder cancer - organic even better Just seen that you've mentioned DHA.  A good quality fish oil (or krill oil), containing high levels of omega 3s, both EPA and DHA, would be very beneficialfor Alex. This would be my third choice! Apart from its proven anti-cancer qualities, its useful for protecting the kidneys, lowering cholesterol levels, plus other health conditions. Please keep us updated. We're all thinking about you and Alex. Garry and Logan (UK). 12 yrs Eng Bull Terrier, livingwith TCC. Dx 1st May 2012 LogansDad Fri, 17 May 2013 00:00:00 GMT I get the Salvestrol from DennistheChemist in the UK - I'm in Australia,  but I think you might be able to source them from Canada. Another thing you might like to investigate is PolyMVA & 4life Transfer Factor Plus & also Siberian Chaga Mushroom. It's a long journey but you'll have lots of support from this forum Deb & Andy tryeverything Fri, 17 May 2013 00:00:00 GMT You should not give up hope! There are lots of people in this group with dogs that have lived a year or more after the diagnosis. There are many options for treatment, with traditional and holistic medicines. We all felt your same emotions after hearing or just fearing the TCC diagnosis, but you will soon find your own way to be strong and face the disease. Even though its hard to hear the news, there's no reason to give up. Get an ultrasound to find out how far the disease has progressed and go from there. You can do this! SienasMom Fri, 17 May 2013 00:00:00 GMT I am so sorry for your loss Holly, and everyones loss. I can tell everyone here knows what I feel. Its been literally a week of hell for me thinking of losing my Alex. Reading these messages was one of the hardest things I've done. Maybe ignorance would be bliss had I not looked things up...I could be happily awaiting the test results of her UTI after 2 weeks. Shes normal again, no excessive peeing, no blood, sleeping all night, good amount of urine. I would think shes better. Except for the cells they saw. Now I'm so afraid of the answers I am going to get. I am happy for the time some of the people here were able to get and those still fighting long battles. But I'm overwhelmed with grief at this all. I do want to know if others who went through UTIs in the begining- if their dogs got better with the antibiotics with the symptoms. If they went away. All hers have but the licking after peeing (done this for as long as I can remember) and occassionally licking her back end or legs. Shes a week into the antibiotics. Is this a good sign, or just false hope. kristinrebecca Fri, 17 May 2013 00:00:00 GMT So sorry to hear this, I have not been here much lately, because it hurts so much to see everyone go through this. Just know that Lizzie did not know she was dying. That was what comforted me the most and my Vet helped me realize that.  She knew she was loved and that is what was most important. Hugs to all of you.  MinnieMo Fri, 17 May 2013 00:00:00 GMT On May 17, 2013 2:04 AM kristinrebecca wrote: Are we talking a cancer specialist? I asked about the ultrasound at the clinic we use and it was approx. $350. What if the clinic I go to has an in house oncologist or if they have someone who they work with? Still a bad idea? Can I ask at my vets office for a referral? I know for a fact we have nothing like a specialists vet clinic in town. The closest may be a couple hours away in Madison.I saw an Intermal Medicine Vet (Didn't even know they had those LOL). I opted not to see an Oncologist after she was diagnosed. I could afford Chemo, and the doc I saw said the odds were not very good anyway. I would ask you vet if he/she can recommend a specialist. 350.00 is a lot for an ultrasound so if you are going to pay it, you may as well make sure you are getting the best care for Alex. As long as you can get the ultrasound and the results immediately and by someone familiar with Canine TCC, that would work too (if you're comfortable with your vet). I just don't want to see anyone make the same mistakes I did. I miss my girl so much and she's only been gone 2 days. Please keep us posted. Holly :-) LizziesMommy Fri, 17 May 2013 00:00:00 GMT Are we talking a cancer specialist? I asked about the ultrasound at the clinic we use and it was approx. $350. What if the clinic I go to has an in house oncologist or if they have someone who they work with? Still a bad idea? Can I ask at my vets office for a referral? I know for a fact we have nothing like a specialists vet clinic in town. The closest may be a couple hours away in Madison. kristinrebecca Fri, 17 May 2013 00:00:00 GMT On May 17, 2013 12:02 AM kristinrebecca wrote: should I just have them do her ultrasound ASAP at the vet office I am at?I wouldn't. I paid almost 300.00 for a mobile imaging place to go to my vet and almost 300.00 2 weeks prior at my vet for bloddwork, x-rays, urinanalysis, antibiotics, etc. Then another 600.00 later that same week (after the ultrasound) at the specialist. The 600.00 included the ultrasound, biospy, pathogogy, general anesthesia and Clavimox (antibiotic). I had the results that same day (a Sat). Had I known, I would have gone straight there. Here is where I went: http://www.palmbeachvetspecialists.com/contact.cfm I'm sure there is a similar type of place near you. They ONLY have specialists. With TCC, regular vets really aren't that familiar with it. If it happens to be TCC, you'll be able to start whichever treatment you decide to go with ASAP. If it isn't, you'll have piece of mind. Regular vets are good for basic things but when it comes to bladder issues, go for the specialist. LizziesMommy Fri, 17 May 2013 00:00:00 GMT should I just have them do her ultrasound ASAP at the vet office I am at? kristinrebecca Fri, 17 May 2013 00:00:00 GMT How do I find a specialist? I live near LaCrosse WI. I know our vet clinic does ultrasounds though. Do you think they won't be able to diagnose this correctly at my current vet? I don't know if I will have the money for specialists and oncologists, chemo, many ultrasounds, surgery.... all for them to tell me theres no cure.  I don't know where I would come up with the money. I'm not sure I want to subject her to anything painful above and beyond what she may already end up with either. Obviously I want to treat her as soon as possible though with whatever I can. Piroxicam and a stomach protectant I guess. I'm just sick to my stomach and haven't been able to eat or sleep for days. All I do is cry. This is supposed to be the happiest time of my life and I'm just devastated. I wonder if its too late to buy pet insurance at this age for her, if they would even cover her or this since so far they've only got her down as a uti. kristinrebecca Thu, 16 May 2013 00:00:00 GMT Alex's mom- I would take her straight to an oncologist. I spent way too much time an money on various vets that did not know enough about TCC. I kept thinking UTI, and did the antibiotics, over and over with no success. The only thing that' has worked has been herbal remedies. First get the ultrasound and find out what she has. I kept thinking the ultrasound was too expensive, and put it off for many urine and blood tests. I bought diapers for my Slice, they help a lot with the dripping and urgent needs you will find to be one more frequent. Lastly, I have not figured out how to create a new post/subject, and I have been here awhile. Kathy and Slice slomokat Thu, 16 May 2013 00:00:00 GMT Holly, Thank you for thinking of us and lighting a candle for Chica. To know that you thought of us in your grief, makes it even more special to me. ChicasMomForever, Lynn ChicasMom Thu, 16 May 2013 00:00:00 GMT Where are you located? I would honestly recommend a specialist. I went over 2 weeks with Lizzie on antibiotics and she never got better. The fact that Alex is feeling better is a wonderful sign. Even after Lizzie went on her Cancer drug (Piroxicam), she still had the need to pee often. Go to a specialist (not an Oncologist yet) and have an ultrasound. A specialist can biopsy it without disturbing it. Lizzie had something called a Traumatic Catherization. Put pull the cells with water and never have to disturb the tumor. They do it under an ultrasound. If it does happen to be cancer, you can start her on a treatment ASAP. I opted to put her on Piroxicam. She lasted 5 weeks. I wonder what would have been if I took her to the specialist immediatley. I thought she had a UTI or worst case, bladder stones. Before you keep relying on your regular vet and spending $$$ there, I promise you'll feel much better if you find out ASAP. Good luck. I'll be praying for you and Alex. <3 LizziesMommy Thu, 16 May 2013 00:00:00 GMT Hi Holly You are so sweet to try and calm me. Even the vet I saw sounded concerned. There was more than a couple cells...she said we don't usually see transitional cells in larger amounts like this with a UTI. I can't find anything about transitional cells in the urine without cancer being present. I know she was trying to prepare me. I have a feeling somethings been brewing in her for awhile...she peed on the deck a couple months ago and I wrote it off to snow still being on the deck and her getting confused...(she used to pee on our concrete patio in the winter.) She had been peeing more often than usual outside but I never felt there was a real issue as this was unlike her previous UTIs which came on fast and bad. I wish I had taken her in a couple months ago. I always thought I was so in tune with her. Shes a week into antibiotics today. Shes peeing normally and I see no blood and she isn't feeling the need to pee often. I want to feel encouraged, but from what I have read that only means shes getting over the infection. She will get urine retested in another 10 days and then they will see about an ultrasound. I just have a sick, horrible dread about what it will show. I didn't think biopsies were recommended due to the tumor being disrupted and possible seeding?  She seems to have symptoms so much like the early ones others have posted. The licking, blood, uti, transitional cells. I would love to be optimistic but I cannot find anything while researching to suggest transitional cells appear for any other reason. I don't want to get my hopes up only to be crushed again.  kristinrebecca Thu, 16 May 2013 00:00:00 GMT On May 16, 2013 8:46 PM kristinrebecca wrote: Forgive me I cannot seem to figure out how to post a message in this thread without replying to someone elses message. My whole world came crashing down last friday. I got my dog Alex into the vet for waking me up early to go out and then peeing on the deck afterward, things she doesn't do. A couple days prior she was peeing frequently in the yard which I thought odd, but didn't ask to go out more in the house. I thought UTI immediately friday since she had others earlier in life. The urine sample came with back a bunch of stuff in it. White cells, blood clot, crystals, transitional cells. I see no reason to hope for good news after her 2 weeks of antibiotics, new urine test and then an ultrasound....after looking up transitional cells theres nothing but cancer in my searches. Shes peeing normally now and I see no blood. she does lick herself after peeing, but has done that for ages from what I can recall. She licks her back end or legs occassionally.  I'm devastated. Shes to be my flower girl in my wedding in August. Shes a part of me. I started her on the Budwig diet of cottage cheese/flax already and started with some broccoli and cauliflower. She gets boiled chicken as treats. I don't feed her bad, grainy food but am going to check if I should switch. Im filtering most of her water now....she likes to sneak drinks from my parents dogs bowl though. I ordered K9Immunity Plus. I'm thinking of adding DHA and green tea if people still feel its helpful. And Im curious about AHCC and Salvestrols though I cant seem to find where you can buy the latter one. Any idea on dosing? My dog is 48lbs.  Shes not been diagnosed yet but I fear she has TCC and thats coming. Fear is not even close to what I feel... beyond terrified. I want to start doing something proactive while I sit and wait for another week plus of her antibiotics and then to get in for retesting and an ultrasound. I already read though nearly every post in here and my brain and a notepad are filled with info, but now I'm not sure what is currently seen as the best ways people are treating beyond Piroxicam & stomach protectors. I'm just heartsick and devastated having read all your posts over the last week. I'm so sad for all of us here. Alexs MommyHi Alex's Mommy. Listen, don't get worried just yet. There is no way they can determine bladder cancer through a urine test. My Lizzie's urine came back with all kinds of stuff and was treated for 2 weeks for a UTI. When she had a regular ultrasound, they detected a mass. Even after the ultrasound was read by a radiologist and they pretty much figured it was TCC, they still had to biopsy her tumor. Alex may just have a UTI resistant to the antibiotics she was taking. Since she is peeing better, that is a WONDERFUL sign. Go to a specialist to make sure but I wouldn't get yourself upset yet. Please keep us all posted. Holly :-) LizziesMommy Thu, 16 May 2013 00:00:00 GMT Thank you for your kind words everyone. This has been so incredibly hard. My other 2 dogs are nothing like Lizzie. She was the most lovable girl on the planet. I miss her so much. Garry, thank you so so much for the candle for Lizzie <3 . I lit 2 candles. 1 for Chica and 1 for Bailey. Pay it forward...<3 to all of us with a pet battling or who has battled this horrible disease. :-( LizziesMommy Thu, 16 May 2013 00:00:00 GMT Forgive me I cannot seem to figure out how to post a message in this thread without replying to someone elses message. My whole world came crashing down last friday. I got my dog Alex into the vet for waking me up early to go out and then peeing on the deck afterward, things she doesn't do. A couple days prior she was peeing frequently in the yard which I thought odd, but didn't ask to go out more in the house. I thought UTI immediately friday since she had others earlier in life. The urine sample came with back a bunch of stuff in it. White cells, blood clot, crystals, transitional cells. I see no reason to hope for good news after her 2 weeks of antibiotics, new urine test and then an ultrasound....after looking up transitional cells theres nothing but cancer in my searches. Shes peeing normally now and I see no blood. she does lick herself after peeing, but has done that for ages from what I can recall. She licks her back end or legs occassionally.  I'm devastated. Shes to be my flower girl in my wedding in August. Shes a part of me. I started her on the Budwig diet of cottage cheese/flax already and started with some broccoli and cauliflower. She gets boiled chicken as treats. I don't feed her bad, grainy food but am going to check if I should switch. Im filtering most of her water now....she likes to sneak drinks from my parents dogs bowl though. I ordered K9Immunity Plus. I'm thinking of adding DHA and green tea if people still feel its helpful. And Im curious about AHCC and Salvestrols though I cant seem to find where you can buy the latter one. Any idea on dosing? My dog is 48lbs.  Shes not been diagnosed yet but I fear she has TCC and thats coming. Fear is not even close to what I feel... beyond terrified. I want to start doing something proactive while I sit and wait for another week plus of her antibiotics and then to get in for retesting and an ultrasound. I already read though nearly every post in here and my brain and a notepad are filled with info, but now I'm not sure what is currently seen as the best ways people are treating beyond Piroxicam & stomach protectors. I'm just heartsick and devastated having read all your posts over the last week. I'm so sad for all of us here. Alexs Mommy kristinrebecca Thu, 16 May 2013 00:00:00 GMT Garry, "She may well give you signs that she is still not far from you..." How true this is!  Sometimes I can hear Chica bark in the backyard...when I am sitting on her favorite porch.  It is so clear sometimes, I have to get up and look around to see if she is really out there.  Other times it sounds like she is in the woods chasing the deer, and is very faint. I hope I never lose this gift she gives me, but I know as time passes it might go away. ChicasMomForever, Lynn  ChicasMom Wed, 15 May 2013 00:00:00 GMT I have just set-up a virtual candle group for dogs living with TCC and for those who've passed. http://www.gratefulness.org/candles/candles.cfm?l=eng&gi The first candle lit is for Lizzie.  Many other dogs have passed as a result of TCC and it's never too late to light a candle for them, in remembrance. We can light a candle at any time - for our dogs who are living with TCC and those that have passed. LogansDad Wed, 15 May 2013 00:00:00 GMT Dear Holly I am so truly sorry to hear about Lizzie. Times like this are very difficult to cope with and I only wish I could take some of the pain away. I do believe that we will once again see our canine family members that have passed - and have no doubt you will be reunited with Lizzie in the future.  In the meantime, I do understand how hard it can be without her physical presence, but she is now running free in spirit, without any of the encumbrances of her physical body. She may well give you signs that she is still not far from you - a familiar smell, an unexpected rainbow appearing, or even a glimpse of something out of the corner of your eye. ..... Before Ellie (Logan's mum) became unwell, I wasn't sure what I believed in.  When we were taking Ellie's body to her final resting place (somewhere we'd never been before) the sun came out of no where - and no less than 2 rainbows appeared en route. They were with us until we arrived, then disappeared. She has shown herself to us in other ways, too. I  now believe in these things. Another example is when a couple of friends were in a closed room in the crematorium, saying their farewells to their dog (another Eng Bull Terrier) who had passed the day before. One of them (believe me, he just isn't the sort of person to hold any spiritual belief or similar) said "I just wish we knew that ****'s OK".  At that moment, one of the daffodils on the table next to their dog, flew off the table toward them.  There were no draughts in the room. I will light a candle for Lizzie. As Deb has said, lavish love on your other dogs and please do look after yourself, Holly - Lizzie would want you too and is never far from you. Garry and Logan LogansDad Wed, 15 May 2013 00:00:00 GMT To Holly, I haven't posted much but have been tracking you & Lizzie journey I can hardly type because of the tears, I can feel your pain & sorrow & when I look down & see my little boy, then the reality of it all sets in. I know what's inside him isn't going away. I grieve with you dear one because this can be the loneliest time.  I lost another little boy 5yrs ago now but sometimes I still have a cry, I miss him. You fought a tremendous battle & are exhausted, now you must look after yourself & keep faith & lavish all your love on your other babies. So take some comfort knowing you did your utmost & beyond for Lizzie. I read of a man on one of these cancer forums that he had lost family members & friends but the grief of losing his best mate, his constant companion - he hadn't experienced anything like it. Ít's so true. I must go & dry my eyes & pull myself together. This comes with deepest sympathy Holly.   Deb & Andy tryeverything Wed, 15 May 2013 00:00:00 GMT Hi, I am so very sorry about your loss.  I will keep you in my thoughts and prayers, and I ask that you try to take care of yourself in the days ahead.  From reading your posts I know how loving and caring you were and what a hard time it was for you before she crossed the rainbow bridge. Love, Nita Nita Wed, 15 May 2013 00:00:00 GMT Holly...I am so sorry...I physically hurt for you and your family. My tears have been many in this last year...we have lost a lot...many of us.  I pray that we all find peace in our hearts and lives and move on from this awful disease, TCC.  I pray that we remember the good times with our loving pets, that were with us for short or long times.  Every minute was a ray of sunshine in our lives and we should be thankful for that. I still offer you that (HUG), tear stained, but from the bottom of my heart. ChicasMomForever, Lynn ChicasMom Tue, 14 May 2013 00:00:00 GMT BRings tears to my eyes. Sorry. slomokat Tue, 14 May 2013 00:00:00 GMT Thank you everyone. She is gone. She went across the rainbow bridge. The really suffered the last few hours and went downhill fast. I had to leave the room. I kissed her and hugged her and told her how much I loved her and that I wou;d see her again. She fought it really hard and I couldn't take it. My husband had to hold her. She is burried in my backyard with our beloved beagle George. The vet said she wasn't emotionally ready because she was only 10 but her body was ready. My husband made me come say goodbye after she was gone. I know she was finally at peace and no longer suffering but my heart still can't take it. I was so hysterical all afternoon. My other 2 dogs don't understand where their sister is :-( I will stay on this board and pray for all your pups because you've all been so helpful to me. Thank you for all your support. Holly...Frizzy, Halo and forever Lizzie's Mom <3 <3 LizziesMommy Tue, 14 May 2013 00:00:00 GMT Holly, I am so sorry. "I'm emotionally and physicallly exhausted"...that's why you felt you were hysterical and that is very understandable.  I did not repond to the earlier post because I knew, in my heart, that you would pull yourself together and focus on Lizzie...and I was right because I know you love Lizzie.  I am sending you a (HUG)...you came through for her. Try to relax and spend some time with her, just talking to her and telling her how you feel about her, give her a belly rub.  Most of the stuff you had to do today, can be done tomorrow or the next day.  Just be with her. I will be thinking of you, your family and especially Lizzie. ChicasMomForever, Lynn ChicasMom Tue, 14 May 2013 00:00:00 GMT Again, so, so sorry, Holly, for all of you...  :( Cathy  Cathtalk Tue, 14 May 2013 00:00:00 GMT Hi Holly-- My heart is breaking for you.  You tried everything you could to keep her going.  You just get to a point where you know it has to be done.  It's been almost 3 months since I had to do it for Bailey.  I still miss her terribly but try to take comfort in the fact that she is at peace and not suffering any longer.  Wishing you peace as well. Karin Baileysmom97 Tue, 14 May 2013 00:00:00 GMT A mobile vet is coming later today to send her over the rainbow bridge in the comfort of her own home, with her family. She chased the mailman today for the last time and had a bowl of ground beef. Lizzie gave me the look today and I know she is suffering. It breaks my heart but I know she will finally be at peace. I consider myself to be so lucky to have had her in my life for 10 years. Holly :-( LizziesMommy Tue, 14 May 2013 00:00:00 GMT She had a terrible night. She was so miserable. She is barely peeing drops. I gave her pain meds and they didn't seem to do much. My husband is in training until 5 so a mobile vet can't come, he is going to take her to a vet. I don't think I'll be able to go. I'm emotionally and physicallly exhausted. My son is graduating high school next week and he wanted her to see him graduate. I haven't event been able to call a vet yet today because I am so hysterical. I thought it would be easier because I've been preparing...it's not. I knew this day would come but was hoping we'd have more time. Thank you all for the support. It's a terrible thing our babies our going through maybe even harder for us. I hate this disease. LizziesMommy Tue, 14 May 2013 00:00:00 GMT Likewise, as LogansDad and Slomokat said, you will make the right decision and it will be the right time for Lizzie.  I'll be praying too. Cathy Cathtalk Tue, 14 May 2013 00:00:00 GMT I have just found something I've not heard of before. Maybe some of you have - Siberian Chaga Mushroom. It sounds like it's worth looking in to. MS is even mentioned on it's list. Andy will have nearly reached the 12mth mark from the time of diagnosis of TCC. I started with K9Immunity & Transfer, Vascustatin, DHA omg3s. Now I have him on RM-10Ultra, AHCC, SAlvestrol, DHA & BIoPreparation & a raw meat & veg diet with some cooked chicken added each time. I hope I am going to see him reach very a old age (he's 13). It's never to late to try something new - nothing to lose. I hope this might help.   All the very best to you & Lizzie, my heart gets heavy reading your posts & I understand your anguish & sadness- we all do on this very compassionate forum, all of us fighting with one goal in mind. I can't help it I'm crying already Deb & Andy tryeverything Tue, 14 May 2013 00:00:00 GMT Please please dont feel guilty......my heart goes out to you. You will make the correct decision for lizzie. Im praying she will be ok. If you have to help her pass on, please try to look upon it as a last act of kindness you can do for her-and it will be through the love you have for her that you do it. I only wish I could do more for you. LogansDad Tue, 14 May 2013 00:00:00 GMT Sorry. Did add link but it wasnt shown on post! Ill add again when on laptop. LogansDad Tue, 14 May 2013 00:00:00 GMT I feel for you- so sorry slomokat Tue, 14 May 2013 00:00:00 GMT On May 14, 2013 2:45 AM slomokat wrote: Try a new vet maybe one that cares enought to call you back, and that may have better insight into the ups and downs of TCC. I too think it was a sign that the mobile vets were not available. Good luck to you and your baby Lizzie.  We are hoping for a big turn around for her. Kathy and SliceI will NEVER gp back there. I actually found 1 really nice mobile vets. As of right now, I don't know how we are going to get through the night. I thought she was feeling a little better but she is really doing badly tonight. I am hoping I won't have to take her to an emergency vet and putting her at peace. I am feeling so guilty right now. LizziesMommy Tue, 14 May 2013 00:00:00 GMT Try a new vet maybe one that cares enought to call you back, and that may have better insight into the ups and downs of TCC. I too think it was a sign that the mobile vets were not available. Good luck to you and your baby Lizzie.  We are hoping for a big turn around for her. Kathy and Slice slomokat Tue, 14 May 2013 00:00:00 GMT On May 13, 2013 6:33 PM LogansDad wrote: I always think it's sensible to switch therapies if there's no evidence of them working, following a reasonable period of time. Good luck with the ultrasound and check up. Dogs living with TCC do get their bad days.  Logan wasn't very well on Sunday, although difficult to tell how much is directly related to this condition. Their immune systems take a bashing from cancer and that's why it's so important to support it as much as possible. We use low-dose tramadol, too. Although it's not related to pain, it does ease the symptoms Logan presents with (long story...).  Sometimes we have no choice but to go with allopathic meds if they're really needed.  I really hope the AHCC and salvestrols will make a difference. I've previously suggested a dose for Bella, based on a study with dogs.  As for thesalvestrols, it's one 1000 point capsule per 40lbs - just a tad below her weight - twice dailywith food- helps with bioavailability.  Here's a link to the salvestrols for dogs group I've just set up. If the diet works for her, Kristian, then carry on with it.  It seems she likes it and has energy. You both take care Garry and LoganHere's a link to the salvestrols for dogs group I've just set up. Garry- you did not add the link. Would you please. Also, I was wondering is Salvestrol a brand name? I see their information site, and that they do not sell the product on this web site, but I am not convinced that they arent just promoting their own product. Any thoughts?  Is it working on Logan? I did read the AHCC info you posted ( I am half way through the 200 or so pages) and I am defintely going to try it on Slice.   If not for me. Are you also giving fluids to Logan?  Does he have to pee every hour or two? Thanks for  all the insightful information, and I hope Logan is having one of his good days.    Kathy and Slice slomokat Tue, 14 May 2013 00:00:00 GMT I'm taking pictures every day. Oh, and I got this from Amazon. We took her paw print today :-( http://www.amazon.com/gp/product/B0007KVOP8/ref=oh_details_o LizziesMommy Mon, 13 May 2013 00:00:00 GMT On May 13, 2013 7:06 PM LogansDad wrote: Hopefully, the fact that none of the 3 mobile vets could come out to you re euthanasia, is fate...... UTI coud be causing her a prob.  Hopefully, the broad spec antibiotic will help. you can get a urine culture carried out to check for bacteria, just in case it's a Clavamox resistant strain. By her actions, you're probably correct in thinking she isn't ready to go jst yet - you know your dog.  Whenever her time comes (hopefully not for some time yet!) she should be at home..... It can be so difficut, but keep strong and enjoy time with Lizzie - and take photos! xI thought the same thing...fate! I hope I am right and don't let her suffer. Before she was diagnosed, she was on Cipro and Cephallexan and neither one helped her at all. After her procedure, they put her on Clavamox to avoid infection and within 2 days of the Piroxicam and Clavamox, she was much better. I don't think they ever did a full urine culture. My vet was supposed to do one the day of her first MRI and I was told they had to get the urine directly out of the bladder with a needle (for the culture). After they saw the mass, they didn't move forward with the culture. I am praying for a miracle that she will feel better in the next day or 2. If not, it's the end of the line for her because I just can't put her through anymore. LizziesMommy Mon, 13 May 2013 00:00:00 GMT Hopefully, the fact that none of the 3 mobile vets could come out to you re euthanasia, is fate...... UTI coud be causing her a prob.  Hopefully, the broad spec antibiotic will help. you can get a urine culture carried out to check for bacteria, just in case it's a Clavamox resistant strain. By her actions, you're probably correct in thinking she isn't ready to go jst yet - you know your dog.  Whenever her time comes (hopefully not for some time yet!) she should be at home..... It can be so difficut, but keep strong and enjoy time with Lizzie - and take photos! x LogansDad Mon, 13 May 2013 00:00:00 GMT Cathtalk makes some good points, Holly, inc the possibility of changing NSAIDs for Lizzie I do appreciate that it's a very worrying time for you. One of Logan's tumours is in the urethra, so it's a constant worry for us, too.  As Cathtalk has said, many of our dogs living with TCC are still doing well, despite the prognoses given by vets. Sending you and Lizzie prays and positive thoughts. Garry and Logan LogansDad Mon, 13 May 2013 00:00:00 GMT I always think it's sensible to switch therapies if there's no evidence of them working, following a reasonable period of time. Good luck with the ultrasound and check up. Dogs living with TCC do get their bad days.  Logan wasn't very well on Sunday, although difficult to tell how much is directly related to this condition. Their immune systems take a bashing from cancer and that's why it's so important to support it as much as possible. We use low-dose tramadol, too. Although it's not related to pain, it does ease the symptoms Logan presents with (long story...).  Sometimes we have no choice but to go with allopathic meds if they're really needed.  I really hope the AHCC and salvestrols will make a difference. I've previously suggested a dose for Bella, based on a study with dogs.  As for thesalvestrols, it's one 1000 point capsule per 40lbs - just a tad below her weight - twice dailywith food- helps with bioavailability.  Here's a link to the salvestrols for dogs group I've just set up. If the diet works for her, Kristian, then carry on with it.  It seems she likes it and has energy. You both take care Garry and Logan LogansDad Mon, 13 May 2013 00:00:00 GMT Hi Cathtalk, She had a really bad night and is only peeing little drops. The Piroxicam was really working and she only had blood that one time (I think it was from the straining). I called 3 mobile vets today to come put her down but none of them could come until tomorrow. One suggested I call her old vet and get antibiotics. Of course, he was busy and hasn't called me back. But next I called her specialist and my husband just went to pick up 2 weeks of Clavamox to see if it helps. They gave her 1 week of Clavamox when she had her procedure and between that and the Piroxicam, she did really well. She was ok untik yesterday but I am hoping this is just a UTI. If she gets better, she is going to the specialist to see if the tumor has grown. She is eating and chased the mailman across the fence so I don't think she is ready to die yet. Plus, I REFUSE to take her back to the old vet. I want her last minutes to be here at home. I think this non stop roller coaster is the worst part of it all :-( LizziesMommy Mon, 13 May 2013 00:00:00 GMT Hi Holly/Lizzie's Mom. How is your girl?  I'm glad to hear that Lizzie no longer has blood in her stools!  Keep her stomach prepped and keep feeding her fiber. Sorry to hear though that she's having a hard time peeing again.    I know how anxious you must feel.  I worried too that if Meg's tumor became too enlarged, it would block the urethra, and then urine would then begin to back up and cause kidney problems/failure.  It is a horrible disease, Holly.  Yet many of our dogs here are bucking some of the direst odds given by the vets with our help.  I know you said earlier you did not rely much on your regular vet -- however, did you ever get Lizzie to an oncologist or ultrasound specialist before or after her procedure (can't remember, was it a catheterization)?  Also, did you switch out the piroxicam?  Did you try any other NSAID, such as Deramaxx?  I ask because I switched my Meg over to that for the remainder of her life and she did much better on it.  She was also a walker to the end -- walking seemed to help at times to keep the flow going. As for vet bills -- I got a line of credit to help me pay for much of Meg's care and our other scottie when he too became terminally ill.  It was a credit card called Carecredit.com offered through GE Capital Retail Bank.  Check it out -- it's easy to apply and credit can be granted instantly.  Lots of vets accept the card. I found Lynn's site again -- I think it is good -- I pasted it in below.  Keep a little journal every day on Lizzie -- just note things about her habits, activity level, energy.  I found the journal helped a bit as it became harder to remember from day to day just how Meg was doing. http://www.veterinarypracticenews.com/vet-practice-news-colu Take care and keep us posted!     Cathtalk Mon, 13 May 2013 00:00:00 GMT hey guys stopped the graviola as i read both good and bad things about it, but wasn't working anyway as thing she i getting a bit worse. she peeing blood a bit more often and is taking a longtime to urinate from what i can see its drops. she is going into vet tomorrow morning for ultrasound and check up. i think she is having a bad day she looks a little bit down. the doctor gave us some tramadol a while ago to give to her if she looks like she is in pain, so i might give her one of those today. i have ordered some AHCC and salvetrols. the tuna and sardines are from a tin in springwater or brine, but she get raw beef, cooked chincken etc. she still hops around and wags the tail, barks at the mail man, wants to play, eats whatever i give her. see what the vet has to say.. anyways give you guy and update after the vet. kristian krimmo Mon, 13 May 2013 00:00:00 GMT On May 13, 2013 1:48 AM slomokat wrote: Just geting an update on how everyone is doing.  No one is posting so I would have to assume all is well in the world of TCC. Slice update-  He is back.  50 yrd walks, lifting his leg, eating like a regular dog, and barking.   He is peeing uncontrolably- every hour or so.  He has a good stream, and goes much quicker these days.  The diarrhea is mostly gone.  Supplements are his mainstay, and so are 2x a day sub q fluids. Oha nd thanks for the advice... I  decided to take the trip to Dubai, but leaving the husband home to babysit.   Happy Moms day to al you doggie moms ( and dads). Slice, and KathySo happy to hear Slice is doing so well!!! I think it's the end of the line for Lizzie. She was actually doing better. Peeing little streams and her poop is pretty normal. Unfortunately, she's back to peeing drops. Due to the location of her tumor, I don't want to wait until she is miserable. I am so torn. :-( LizziesMommy Mon, 13 May 2013 00:00:00 GMT Just geting an update on how everyone is doing.  No one is posting so I would have to assume all is well in the world of TCC. Slice update-  He is back.  50 yrd walks, lifting his leg, eating like a regular dog, and barking.   He is peeing uncontrolably- every hour or so.  He has a good stream, and goes much quicker these days.  The diarrhea is mostly gone.  Supplements are his mainstay, and so are 2x a day sub q fluids. Oha nd thanks for the advice... I  decided to take the trip to Dubai, but leaving the husband home to babysit.   Happy Moms day to al you doggie moms ( and dads). Slice, and Kathy slomokat Mon, 13 May 2013 00:00:00 GMT On May 04, 2013 3:15 PM LogansDad wrote: .......and a year living with TCC, post diagnosis. I forgot to wish Logan a happy 12th birthday.  Congrats on the milestone for living with TCC. ElvWestie Wed, 08 May 2013 00:00:00 GMT kimmo, Sorry to hear about the lack of vet help.  Can you take Bella to another vet for a second opinion? Dr. Dressler offers the food excerpt of his Dog Cancer Survival Guide for free.  He even has a blog and videos.  At the very least, listening to him makes you feel like you have more control over the cancer. http://www.dogcancerblog.com/meet-dr-dressler/ http://www.dogcancer.tv/  https://www.youtube.com/user/DogCancerVet/videos?view=0&nbsp "i hope i am doing the right thing with all the extra supplements."  You're doing everything that you can for your dog no matter what happens.  Every decision that you make is the right decision for your dog.  Dr. Dressler even addressed guilt as internalized anger, or anger pointed toward the owner.      ElvWestie Wed, 08 May 2013 00:00:00 GMT Hello Kristian Really sorry to hear about Bella. If she's having any NSAID (non steroidal anti-inflammatory) such as Piroxicam she MUST DEFINITELY BE ON A STOMACH PROTECTANT and also, the NSAID must be given with a meal. Is she hasdark bloody stools, that indivcates it could be from the upper part of the gastrointestinal track and has v likely been caused by the Piroxicam. Have you told your vet re this? Plse do so, if not. If it were me (I'm not a vet) I would stop the NSAID immediately, speak with your vet and discuss a protocol for reintroducing the Piroxicam, following a few days' break - and then with a stomach protectant, such as Prilosec (omeprazole). Continuing with Piroxicam w/o any protection could lead to ulcers..... AHCC.  IMO I'd start at 1000mg, split into two, 500 mg doses for a dog weighing 22kg.  Give before meals (30 mins is enough).  Re. above - I based our dosage for Logan, on study carried out with dogs to show incresae in natural killer cell activity.  It ranged from 50mg/kg to 100mg/kg.    The AHCC Research people recommended the following in a recent e-mail I recd from them. As said, I opted for the study's dosage which is higher than the following: Therapeutic              Maintenance Large Pet (75lbs)                      1.5grams                     500mg           Small Pet (32.5lbs)                   500mg                      250mg Logan (25kg) is currently receiving 1000mg, twice daily and I will be increasing to 1,250mg twice daily, from tomorrow. This is the upper dose used in study with dogs. Jujst out of interest, are the tuna and sardine, raw? If she was following a completely raw diet, you may find that she would be 'regular' in any case (taking into consideration any other health conditions).  Since changing to raw, Logan's stools have never been better.. Sorry to hear about the response from your vet.  Sadly, whilst there are indeed some excellent vets out there, equally, there are some who appear to be lacking in knowledge of ceratin haelth conditions - TCC being one. The number of supplements is probably something many people question themselves over, Kristian.....you're not alone with that! IMO the more you give, the less likely you are of knowing about any possible interactions. I always endeavour to thoroughly check out any new supps for Logan, but even then it can sometimes be a leap of faith! "she seems to not be in too much pain.."   do you believe she is in some pain then?  if so, this would need to be addressed... Great that Bella's appetite is good! The only other supp I would consider (no doubt others have their 'preferences') is salvetrols.  Backed by some sound evidence and co-discovered by a guy (Gerry Potter) who has helped develop chemo drugs.  Logan started this the same time as AHCC.  As for the other supps Bella's receiving..,I'm no expert, but I would certainly double-check the use of graviola for dogs - believe I've read it may not be good for dogs living with cancer - Google something like 'graviola for dogs' and see what comes up. Plse keep us informed.   LogansDad Wed, 08 May 2013 00:00:00 GMT just read some more and she has really darks stools as well. think she should be on some sort of stomach protection? which one is best and how much should i give her? krimmo Wed, 08 May 2013 00:00:00 GMT hey guys my dog bella has had tcc of the bladder now for about 2 months. just wondering about the dosage of AHCC? she is a kelpi, 22kgs and 13 years old. i have her on raw food diet  (mince, chicken, veggies. but mostly tuna and sardines and little bit of dog food (dry food) to keep her regular. she gets cranberry supp x 1 cap a day, echinacea drops both breakfast and dinner, graviola caps x1 breakfast, lunch and dinner, glucosamine x1 caps a day, the only thing the vet has said to give her was the piroxicam.. he was not much help. i hope i am doing the right thing with all the extra supplements. she has her up days and bad days. little bit of blood every no an then and its very light (not thick). she trys to pee all the time though. is there anything else i should be doing? she seems to not be in too much pain, its had to tell but she is a big eater. she would eat herself to death if i kept feeding her i always would say. so i guess when she stops eating. i would think something is very wrong. anyways thats bella and i story any help would be appreciated. kristian krimmo Wed, 08 May 2013 00:00:00 GMT Oh no no no, she had Piroxicam last night (Monday) and I will give her another one tomorrow morning (Wednesday). I always give her Piroxicam after her large meal and her antacid pill. Yes, that's exactly where it is. The doctor said it's in the worst possible place. It is so heartbreaking and what makes it worse is my male wheaten knows something is terribly wrong with his sister and he doesn't know what to do with himself. LizziesMommy Tue, 07 May 2013 00:00:00 GMT Piroxicam should only be given once daily!DO NOT give during the night and then the next morning I do understand your concern about ensuring Lizzie doesn't have to go through any emergency procedure, but giving two doses of piroxicam over such a short period may cause more problems than it will solve.  Also, just to reiterate: Piroxicam should always be given with a meal (or immediately foillowing) I'm assuming the tumour is in the neck of the bladder or in the urethra?  This is also the position we we are dealing with, with Logan. yes, you're so right,her quality of life is paramount, Holly. LogansDad Tue, 07 May 2013 00:00:00 GMT Chicasmom, Logansdad, Slomokat and Cathtalk, I really appreciate all your help. When the specialist put Lizzie on Piroxicam, she mentioned there may be side effects such as upset stomach, blood, vomiting, etc, but never offered any tips to prevent. Her regular vet is useless. I don't know what I would have done if I hadn't found this wonderful group. Plus, most of my friends and family don't understand what I am going through. Even though many have pets, it's not the same for them. Lizzie has been doing better. No blood since Sunday morning. I ended up giving her Piroxicam last night and she will get it again tomorrow morning. With the location of her tumor, any growth would prevent her from urinating. The morning she had her traumatic catherization, she wasn't able to pee at all so I never want her to go through that again. I started her on Prilosec (Omeprazole) this morning and I gave her a Fish Oil gel tab, She had her first meal of the day of plain ground beef, organic sweet potato and a little hard food. I am taking one day at a time and making sure she has a great quality of life and I have you guys to thank for it. I was ready to call the mobile vet in a month ago and she is still going strong. :-) LizziesMommy Tue, 07 May 2013 00:00:00 GMT That's good to hear, Holly! I'm guessing you're in the US(?), so a dose of 0.25mg-0.5mg/pound (Prilosec). However, I'm not a vet, so check with your vet. There are side effects to every drug and this includes Prilosec.  However, as with all drugs, some dogs tolerate them better thah others. feeding 3 meals rather then 2 is a good idea. you could ask your vet for another type of NSAID, other than Piroxicam. "Unfortunately, she won't be able to live without the Piroxicam."........ I wish i could offer a guarantee that this won't be the case, Holly.  However, it doesn't mean that IT WILL be the case, either.  NSAIDs are good at reducing inflammation and those of us whose dogs are living with TCC, know that it can be a double-edged sword (may reduce inflammation, but can also cause nasty side effects).  Either way, if it were me, I'd be looking at ensuring that she has extra anti-inflammatory help, in the form of high level EPA/DHA omega 3 fish oil.  Also, I would STRONGLY CONSIDER introducing her to AHCC (backed by the types of studies - including double-blind - that vets often 'love'!).  AHCC can raise the levels of natural killer cells to help support Lizzie with the TCC, BUT it also has anti-inflammatory qualities. If you need further info plse let me know. this isn't necessarily the 'end of the road' Holly.  Only a couple or so weeks ago, we weren't sure if Logan would be seeing his 12th birthday.  He did celebrate it, had a lovely walk along the seafront near to where we live....He has had a dramatic turn a round.  Of course all dogs are individuals, but there are still things you can do to help Lizzie.  I wish i could say that everything will be OK, but that would be reckless of me to do so. Most vets, however well intentioned or experienced will not often look 'outside the box' of allopathic medicine. I have heard of vets who have sent dogs home with nothing more than pain relief when presented with TCC, with the "there's nothing more we can do" words resounding in the ears of the dogs' carers..  Our own oncologist said that Logan would get progressively worse without continuing with chemo and go downhill - he has got progressively better (in terms of how he feels) without chemo or NSAIDs and is certainly going to the top of the hill! Our own vet thought it a bad idea to switch to a raw diet.  At the time our boy was fading before our eyes, losing weight and not eating regularly. He is now eating raw and enjoys each meal and gaining weight. I can only share my experiences with you, so that you can make an informed judgement about what action you take. Plse keep us informed. LogansDad Tue, 07 May 2013 00:00:00 GMT On May 06, 2013 6:55 PM LizziesMommy wrote: Thanks so much for all your help! She's been better since yesterday morning. No more blood and she's been active and eating. Logansdad, you mentioned Prilosec. What dosage would you recommend and how many times a day? I have extra strength here. Also, I am going to feed her 3 small meals a day to keep her belly full. I stopped the Piroxicam yesterday and don't think I will give it to her again until tomorrow. Unfortunately, she won't be able to live without the Piroxicam. She specialist said there is nothing more they can do for her and I don't want to go back to my regular vet but I may go in and ask for something stronger to make sure her tummy is ok. Holly :-)My Westie Elv is about 22.5lbs, and the vet recommended Pepcid, 5mg.  I give it to him 1/2 hour before his first meal.  I give him piroxicam 1/2 hour after his second meal.  After reading what LogansDad said about Prilosec, I want to switch from Pepcid to Prilosec.  What's frustrating is that the vet didn't mention the side effects of piroxicam.  I feel that I have to do all the research and work to help my dog. ElvWestie Tue, 07 May 2013 00:00:00 GMT Holly- I stopped the Piroxicam, and everything got better. Slice was throwing up, lethargic and unhappy while on the drug.   He still pees every two hours, but with diapers life is great. kathy slomokat Tue, 07 May 2013 00:00:00 GMT Thanks so much for all your help! She's been better since yesterday morning. No more blood and she's been active and eating. Logansdad, you mentioned Prilosec. What dosage would you recommend and how many times a day? I have extra strength here. Also, I am going to feed her 3 small meals a day to keep her belly full. I stopped the Piroxicam yesterday and don't think I will give it to her again until tomorrow. Unfortunately, she won't be able to live without the Piroxicam. She specialist said there is nothing more they can do for her and I don't want to go back to my regular vet but I may go in and ask for something stronger to make sure her tummy is ok. Holly :-) LizziesMommy Mon, 06 May 2013 00:00:00 GMT Hi Holly Sorry, but I've only just read this.... Lynn does make some good points. My sixpenneth:..... Pepcid AC (famotidine) or Zantac (ranitidine) aren't always the drug of choice by oncologists when looking for an effective stomach protectant, when using NSAIDs.  I have previously mentioned Prilosec (omeprazole) in other posts.  I would certainly ask your vet/onc about this. NSAIDs can cause problems in dogs (Logan can't tolerate them,due to nausea and sometimes odd behaviour - he also had bleeding in the past) such as the symptoms you've described with Lizzie.  However, some dogs can tolerate them well. I would certainly speak with/see a vet as soon as poss.  In the meantime, if it were me, I'd temporarily stop the Piroxicam.  Apart from bleeding, ulcers can occur as a result of NSAID use, which will then require additional meds to deal with that e.g. Antepsin. Previcox, is sometimes seen as a NSAID with less side effects. However, I AM NOT A VET, but this is my best advice, based on what you're saying. A short (few days)break from the piroxicam may be the best thing to do straight away. Cathy mentioned canned pumpkin - we have used this to good effect.  Also, please make sure Lizzie is drinking enough, to keep her hydrated. It can be very worrying when our dogs present with symptoms we'd rather not see.  However, they can sometimes be far stronger than we give them credit for.  Plse keep us all posted. LogansDad Mon, 06 May 2013 00:00:00 GMT Hi Holly.  Sorry to hear about Lizzie's latest upset.  Lynn has some good advice. I'm guessing by now you will probably get Lizzie to see her vet soon.  You may want to ease off the piroxicam for a little while if you are still seeing blood in her stools.  Maybe adding some more fiber might help ease her straining a bit -- I used to feed Meg canned pumpkin or sweet potato, as well as lots of broth/water. Cathy Cathtalk Mon, 06 May 2013 00:00:00 GMT On May 05, 2013 5:56 PM ChicasMom wrote: Hi Holly, I'm so sorry Lizzie is having a problem.  You may have to ask her vet/onlcologist about a more protective stomach/intestine med.  I don't know what she is on right now, but the piroxicam can cause black tarry stool (digested blood) from stomach problems or red blood from intestines (non digested blood). Another thought might be (if Lizzie has been straining to poop a lot) an anal fissure, which would bleed some with a stool.  I don't know how much blood you have seen but the vet/oncologiest would know more about where the blood is coming from. Don't be devastated...yet.  How is she acting?  Our animals have the capability of feigning wellness when they are not well.  You will have to try to remember how she acted prior to TCC and gauge how she is acting now.  Another thing is to go down the "Quality of Life" scale (this was very helpful to us).   http://www.veterinarypracticenews.com/images/pdfs/Quality_of _Life.pdf"" target="_blank" rel="nofollow">http://www.veterinarypracticenews.com/images/pdfs/Quality_of target="_blank" rel="nofollow">http://www.veterinarypracticenews.com/images/pdfs/Quality_of These are good questions to ask yourself to determine how things are going. Unfortunately TCC has more questions than answers.  If you are asking about "THAT" call...please find out about what is causing the blood before you make any decision. Call her vet/oncologist tomorrow and figure it out together. ChicasMomForever, Lynn P.S.  Chica had TCC in the trigone area and urethra...we treated both...somewhat successfully.Thanks Lynn, Lizzie doesn't have an Oncologist. She's been taking Pepcid 2x a day before her 2 meals. She takes her Piroxicam after her first meal (her large meal). Yesterday, she got her large meal and Piroxicam a little later (I was so exhausted yesterday). It's my fault. The blood is red. She has been straining to poop since before her diagnosis but when she went, it was ok. I monitored her every time. I am so not ready to lose my sweet girl yet. LizziesMommy Sun, 05 May 2013 00:00:00 GMT Hi Holly, Our posts pasted in mid air. Ask you vet/oncologist about sucralfate or misoprostol as a stomach protectant.  Chica was on misoprostol with her piroxicam for almost three and a half years and we never had a problem.  She also took an original Pepcid before bed every night...just for good measure. I hope this helps. ChicasMomForever, Lynn ChicasMom Sun, 05 May 2013 00:00:00 GMT Hi Holly, I'm so sorry Lizzie is having a problem.  You may have to ask her vet/onlcologist about a more protective stomach/intestine med.  I don't know what she is on right now, but the piroxicam can cause black tarry stool (digested blood) from stomach problems or red blood from intestines (non digested blood). Another thought might be (if Lizzie has been straining to poop a lot) an anal fissure, which would bleed some with a stool.  I don't know how much blood you have seen but the vet/oncologiest would know more about where the blood is coming from. Don't be devastated...yet.  How is she acting?  Our animals have the capability of feigning wellness when they are not well.  You will have to try to remember how she acted prior to TCC and gauge how she is acting now.  Another thing is to go down the "Quality of Life" scale (this was very helpful to us).   http://www.veterinarypracticenews.com/images/pdfs/Quality_of These are good questions to ask yourself to determine how things are going. Unfortunately TCC has more questions than answers.  If you are asking about "THAT" call...please find out about what is causing the blood before you make any decision. Call her vet/oncologist tomorrow and figure it out together. ChicasMomForever, Lynn P.S.  Chica had TCC in the trigone area and urethra...we treated both...somewhat successfully. ChicasMom Sun, 05 May 2013 00:00:00 GMT On May 05, 2013 5:37 PM slomokat wrote: Personally I havent gotten to the blood in poo stage, but i would give it a day or two and see if it contnues.  MAybe change things up witht hemeds or diet and see if that helps. Best of luck. Kathy ( and Slice)Thanks Kathy. I gave her a Zantac (instead of Pepcid) and am going to feed her small meals of protein today.  I am also going to skip the Piroxicam today to see if maybe her tummy was just upset. I am NOT ready to let her go yet. It has only been a month since her diagnosis :-( LizziesMommy Sun, 05 May 2013 00:00:00 GMT Personally I havent gotten to the blood in poo stage, but i would give it a day or two and see if it contnues.  MAybe change things up witht hemeds or diet and see if that helps. Best of luck. Kathy ( and Slice) slomokat Sun, 05 May 2013 00:00:00 GMT My sweet Lizzie pooped blood this morning. She never had any blood in her poop. I only fed her once yesterday so I wonder if that could be the problem. I am so devastated. I don't know if it's time to make that call to the mobile vet. Please help me. :-( Holly LizziesMommy Sun, 05 May 2013 00:00:00 GMT The best news ever, can't keep a good boy down (for long anyway). Logan will reach very old age. Yes! We pass the 1yr milestone at the end of this month. Well done Garry & Logan. Deb & Andy tryeverything Sun, 05 May 2013 00:00:00 GMT On May 04, 2013 3:15 PM LogansDad wrote: .......and a year living with TCC, post diagnosis. Happy Birthday Logan!!! <3 <3 What a wonderful milestone for you guys! LizziesMommy Sat, 04 May 2013 00:00:00 GMT Whoo Hoo, keep them years coming. slomokat Sat, 04 May 2013 00:00:00 GMT HAPPY BIRTHDAY LOGAN! Keep plugging away Garry.  Every good day for Logan is a worthwhile day...make them your own. ChicasMomForever, Lynn ChicasMom Sat, 04 May 2013 00:00:00 GMT .......and a year living with TCC, post diagnosis. LogansDad Sat, 04 May 2013 00:00:00 GMT On May 03, 2013 1:55 AM slomokat wrote: GREAT NEWS. Previously Slice had the following lab report Thu Apr 18, 2013 06:25 PM  Bun 232, creatinine 11.7, Phosphorus 17.  - "maybe two weeks to live" TONIGHTs Levels  Bun 95 , creatinine 5.6  ( no Phosphorus tested) I am so happy I could scream. All the hard work seems to be paying off.     Here is what we have been doing: 2x a day sub Q fluids, Pepcid in the morning, and Aluminum Hydroxide gel - when ever he eats a big meal, and a 30 detox/cleanse program from herbdoc.com "" target="_blank" rel="nofollow">http://herbdoc.com " target="_blank" rel="nofollow">herbdoc.com .  If you decide to go this route- call then on the phone, and they will tell you what you need based on your dogs needs. YIPEEE!!!!! ( thanks for letting me share - this board helps me quite a bit) Kathy  & Slice.   That's brilliant news Kathy! LogansDad Fri, 03 May 2013 00:00:00 GMT On May 03, 2013 1:55 AM slomokat wrote: GREAT NEWS. Previously Slice had the following lab report Thu Apr 18, 2013 06:25 PM  Bun 232, creatinine 11.7, Phosphorus 17.  - "maybe two weeks to live" TONIGHTs Levels  Bun 95 , creatinine 5.6  ( no Phosphorus tested) I am so happy I could scream. All the hard work seems to be paying off.     Here is what we have been doing: 2x a day sub Q fluids, Pepcid in the morning, and Aluminum Hydroxide gel - when ever he eats a big meal, and a 30 detox/cleanse program from herbdoc.com "" target="_blank" rel="nofollow">http://herbdoc.com " target="_blank" rel="nofollow">herbdoc.com .  If you decide to go this route- call then on the phone, and they will tell you what you need based on your dogs needs. YIPEEE!!!!! ( thanks for letting me share - this board helps me quite a bit) Kathy  & Slice.   That's wonderful news!!! :-) LizziesMommy Fri, 03 May 2013 00:00:00 GMT GREAT NEWS. Previously Slice had the following lab report Thu Apr 18, 2013 06:25 PM  Bun 232, creatinine 11.7, Phosphorus 17.  - "maybe two weeks to live" TONIGHTs Levels  Bun 95 , creatinine 5.6  ( no Phosphorus tested) I am so happy I could scream. All the hard work seems to be paying off.     Here is what we have been doing: 2x a day sub Q fluids, Pepcid in the morning, and Aluminum Hydroxide gel - when ever he eats a big meal, and a 30 detox/cleanse program from herbdoc.com .  If you decide to go this route- call then on the phone, and they will tell you what you need based on your dogs needs. YIPEEE!!!!! ( thanks for letting me share - this board helps me quite a bit) Kathy  & Slice.   slomokat Fri, 03 May 2013 00:00:00 GMT On May 02, 2013 2:27 AM slomokat wrote: Logans Dad, can you please see if you can find the info regarding broccoli. We have pretty much stopped giving Slice any harsh medicine/chemo, and have decided to go the  more holistic route. It seems to be working.  But any new ideas would be most appreciated. On a personal note I have been stressing out over an upcoming 1 week  vacation- just cannot decide if I shoudl go or stay with my baby.  Its to Dubai and Jordan, so not something I really want to pass on, but I guess I will know more after I get his Chem work done tomorrow.   ( sorry- had to talk this off my chest) Thanks, Kathy and SliceKathy, I agree with Logansdad. It is definitely a personal choice. As long as slice is happy with someone else and you can go and are able to enjoy yourself without any guilt, I say "go for it!". Personally, I stress out when I have to leave her for 4 hours so traveling anywhere while she is here is not possible. I am not really a huge traveler so it's easier for me to pass up. Whatever your decision, I'm sure it's going to be a hard one so do whatever you choose as the best option for you. <3 Holly :-) LizziesMommy Thu, 02 May 2013 00:00:00 GMT On May 02, 2013 9:43 AM LogansDad wrote: On May 01, 2013 6:37 PM LizziesMommy wrote: On May 01, 2013 10:45 AM LogansDad wrote: On May 01, 2013 4:28 AM LizziesMommy wrote: I'm reading that the dogs get more UTI's with TCC so I was wondering which antiobiotic I should ask the vet for. I think Lizzie may have one. I am hoping he will just give me one without seeing her. Thanks! Holly :-)Hi Holly Why do you suspect a UTI? what are her symptoms? It very much depends on what the UTI is, i.e. what bacteria you're dealing with.  The only way to be sure is to have a urinalysis carried out with a culture grown (takes a few days) to see what bacteria Lizzie has. You'd take a urine sample (free catch) to your vet in a sterile container (vet'll provide this). If you really want to deal with any bacteria now because you feel the infection is causing a big prob now, I'd discuss with your vet re a broad spectrum antibiotic such as Synulox (also known as Noroclav) until you get teh results back from the culture.  If the culture confirms that there is bacterial growth and it's susceptible to Synulox, then it would be a course for a few weeks. However, you may have to cahnge antibiotics if bacteria won't be killed by this antibio.  I'd also say that the only way of checking the progress of this is to have furtrher cultures grown at appropriate intervals. I doubt the vet will give you any antibiotics unless they've recently treated Lizzie foir the same issue.  It depends on what relationship you have with your vet, but by seeing Lizzie it may safeguard her against having any unecessary antibiotics. plse let me know how you get on. Juyst to confirm - I'm not a vet. all the best Garry Thanks Gary, She had a rough night Monday night so I thought she may have another UTI. She is still straining. Even though she is finally going in little streams, she still stands there for several minutes after and strains. She also strains to poop. When she finally goes, it is pretty normal (no blood or anything).   I just want to make sure she doesn't suffer. Thanks so much for your help!   Holly :-)You're welcome Holly. Has Lizzie seen her vet recently?  If she's continuing to strain this could lead to her not being able to wee and with a full bladder that could lead to an emergency situation.  I don't want to worry you, but if she's still straining, she should really be seeing her vet. Please let me know how she progresses.Logansdad, she hasn't seen the vet since she was diagnosed almost 4 weeks ago. She is actually peeing well. The day she went for her Traumatic Catherization, she wasn't able to go at all. They said the straining is due to the location of the tumor and if she wasn't able to go, they could cath her. Since the procedure and Piroxican, she's been going better and better. I actually monitor every time she goes. At night, I go out with a flashlight because I know when she starts having a problem going, her time has come. I am dreading that day. :-( LizziesMommy Thu, 02 May 2013 00:00:00 GMT On May 02, 2013 2:27 AM slomokat wrote: Logans Dad, can you please see if you can find the info regarding broccoli. We have pretty much stopped giving Slice any harsh medicine/chemo, and have decided to go the  more holistic route. It seems to be working.  But any new ideas would be most appreciated. On a personal note I have been stressing out over an upcoming 1 week  vacation- just cannot decide if I shoudl go or stay with my baby.  Its to Dubai and Jordan, so not something I really want to pass on, but I guess I will know more after I get his Chem work done tomorrow.   ( sorry- had to talk this off my chest) Thanks, Kathy and Slice Here you go, Kathy Some are specific to bladder cancer and others more general cancer: http://www.sciencedaily.com/releases/2011/01/110127110707.ht http://www.sciencedaily.com/releases/2011/09/110913091559.ht http://www.sciencedaily.com/releases/2010/10/101022072556.ht http://nutritionfacts.org/video/raw-broccoli-and-bladder-can http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901397/ http://www.ncbi.nlm.nih.gov/pubmed/23038615 I'd also suggest you take a look at salvestrols and AHCC. Logan's receiving these. Loads via Google. Here are a couple of links: http://www.ahccresearch.com/ http://www.salvestrol.ca/more_info.asp I'm really pleased that the holistic route seems to be working for Slice :-) As for the vacation - very much a personal thing, Kathy. I've no prob in you getting this off of your chest, but not sure I can answer this:-) All I can say is, if Slice's used to you going away, is happy staying with someone she trusts and she seems to be well... Let me know how things go. All best Garry and Logan LogansDad Thu, 02 May 2013 00:00:00 GMT On May 01, 2013 6:37 PM LizziesMommy wrote: On May 01, 2013 10:45 AM LogansDad wrote: On May 01, 2013 4:28 AM LizziesMommy wrote: I'm reading that the dogs get more UTI's with TCC so I was wondering which antiobiotic I should ask the vet for. I think Lizzie may have one. I am hoping he will just give me one without seeing her. Thanks! Holly :-)Hi Holly Why do you suspect a UTI? what are her symptoms? It very much depends on what the UTI is, i.e. what bacteria you're dealing with.  The only way to be sure is to have a urinalysis carried out with a culture grown (takes a few days) to see what bacteria Lizzie has. You'd take a urine sample (free catch) to your vet in a sterile container (vet'll provide this). If you really want to deal with any bacteria now because you feel the infection is causing a big prob now, I'd discuss with your vet re a broad spectrum antibiotic such as Synulox (also known as Noroclav) until you get teh results back from the culture.  If the culture confirms that there is bacterial growth and it's susceptible to Synulox, then it would be a course for a few weeks. However, you may have to cahnge antibiotics if bacteria won't be killed by this antibio.  I'd also say that the only way of checking the progress of this is to have furtrher cultures grown at appropriate intervals. I doubt the vet will give you any antibiotics unless they've recently treated Lizzie foir the same issue.  It depends on what relationship you have with your vet, but by seeing Lizzie it may safeguard her against having any unecessary antibiotics. plse let me know how you get on. Juyst to confirm - I'm not a vet. all the best Garry Thanks Gary, She had a rough night Monday night so I thought she may have another UTI. She is still straining. Even though she is finally going in little streams, she still stands there for several minutes after and strains. She also strains to poop. When she finally goes, it is pretty normal (no blood or anything).   I just want to make sure she doesn't suffer. Thanks so much for your help!   Holly :-)You're welcome Holly. Has Lizzie seen her vet recently?  If she's continuing to strain this could lead to her not being able to wee and with a full bladder that could lead to an emergency situation.  I don't want to worry you, but if she's still straining, she should really be seeing her vet. Please let me know how she progresses. LogansDad Thu, 02 May 2013 00:00:00 GMT Logans Dad, can you please see if you can find the info regarding broccoli. We have pretty much stopped giving Slice any harsh medicine/chemo, and have decided to go the  more holistic route. It seems to be working.  But any new ideas would be most appreciated. On a personal note I have been stressing out over an upcoming 1 week  vacation- just cannot decide if I shoudl go or stay with my baby.  Its to Dubai and Jordan, so not something I really want to pass on, but I guess I will know more after I get his Chem work done tomorrow.   ( sorry- had to talk this off my chest) Thanks, Kathy and Slice slomokat Thu, 02 May 2013 00:00:00 GMT On May 01, 2013 10:45 AM LogansDad wrote: On May 01, 2013 4:28 AM LizziesMommy wrote: I'm reading that the dogs get more UTI's with TCC so I was wondering which antiobiotic I should ask the vet for. I think Lizzie may have one. I am hoping he will just give me one without seeing her. Thanks! Holly :-)Hi Holly Why do you suspect a UTI? what are her symptoms? It very much depends on what the UTI is, i.e. what bacteria you're dealing with.  The only way to be sure is to have a urinalysis carried out with a culture grown (takes a few days) to see what bacteria Lizzie has. You'd take a urine sample (free catch) to your vet in a sterile container (vet'll provide this). If you really want to deal with any bacteria now because you feel the infection is causing a big prob now, I'd discuss with your vet re a broad spectrum antibiotic such as Synulox (also known as Noroclav) until you get teh results back from the culture.  If the culture confirms that there is bacterial growth and it's susceptible to Synulox, then it would be a course for a few weeks. However, you may have to cahnge antibiotics if bacteria won't be killed by this antibio.  I'd also say that the only way of checking the progress of this is to have furtrher cultures grown at appropriate intervals. I doubt the vet will give you any antibiotics unless they've recently treated Lizzie foir the same issue.  It depends on what relationship you have with your vet, but by seeing Lizzie it may safeguard her against having any unecessary antibiotics. plse let me know how you get on. Juyst to confirm - I'm not a vet. all the best Garry Thanks Gary, She had a rough night Monday night so I thought she may have another UTI. She is still straining. Even though she is finally going in little streams, she still stands there for several minutes after and strains. She also strains to poop. When she finally goes, it is pretty normal (no blood or anything).   I just want to make sure she doesn't suffer. Thanks so much for your help!   Holly :-) LizziesMommy Wed, 01 May 2013 00:00:00 GMT Hi If Lizzie is doing well with Pepcid AC as a stomach protectant, I see no reason to swap Prilosec for this - 'if it ain't broke, don't try to fix it' may be a good thing to stick to? If she does get any symptoms (blood in poo, etc.) then let your vet know and maybe the Prilosec could be used, following a suitable break from any NSAID. Chemo's a very personal choice.  It isn't for evryone.  There are pros and cons to this.  I'm glad you no longer feel guilty about your decision not to go down this route - you have no reason to feel guilty.  there are some good supplements out there, which may halp to support Lizzie - mentioned in previous posts. I believe certain veggies can be very good for dogs living with cancer, especially cruciferous veg, such as brocolli. Lots of studies shown effective of broccoli/broc sprouts against bladder cancer - i can dig out the links if you'd like. all best LogansDad Wed, 01 May 2013 00:00:00 GMT On May 01, 2013 4:28 AM LizziesMommy wrote: I'm reading that the dogs get more UTI's with TCC so I was wondering which antiobiotic I should ask the vet for. I think Lizzie may have one. I am hoping he will just give me one without seeing her. Thanks! Holly :-)Hi Holly Why do you suspect a UTI? what are her symptoms? It very much depends on what the UTI is, i.e. what bacteria you're dealing with.  The only way to be sure is to have a urinalysis carried out with a culture grown (takes a few days) to see what bacteria Lizzie has. You'd take a urine sample (free catch) to your vet in a sterile container (vet'll provide this). If you really want to deal with any bacteria now because you feel the infection is causing a big prob now, I'd discuss with your vet re a broad spectrum antibiotic such as Synulox (also known as Noroclav) until you get teh results back from the culture.  If the culture confirms that there is bacterial growth and it's susceptible to Synulox, then it would be a course for a few weeks. However, you may have to cahnge antibiotics if bacteria won't be killed by this antibio.  I'd also say that the only way of checking the progress of this is to have furtrher cultures grown at appropriate intervals. I doubt the vet will give you any antibiotics unless they've recently treated Lizzie foir the same issue.  It depends on what relationship you have with your vet, but by seeing Lizzie it may safeguard her against having any unecessary antibiotics. plse let me know how you get on. Juyst to confirm - I'm not a vet. all the best Garry LogansDad Wed, 01 May 2013 00:00:00 GMT I'm reading that the dogs get more UTI's with TCC so I was wondering which antiobiotic I should ask the vet for. I think Lizzie may have one. I am hoping he will just give me one without seeing her. Thanks! Holly :-) LizziesMommy Wed, 01 May 2013 00:00:00 GMT Something to make YOUR life easier.... In case any one is interested, I purchased "Washable Wonders" from dogquality.com and it has made my life so much easier. They are reusable diapers that velcrow on and can be tossed in the landry machine.  Just make sure you buy the extra pads. Instead of Slice peeing uncontrolably all over himself while he sleeps, the pads soak up the liquid, and I just put him out to finish his business.  Slice must pee  at least 4 times a night, so I had to buy quite a few wraps, and quite a few pads.  But, no more washing the dog, and the dog bed, and my comforter every day. CAnt say enough about the belly band. slomokat Wed, 01 May 2013 00:00:00 GMT On Apr 29, 2013 4:47 PM ElvWestie wrote: Cathtalk, Slomokat, Mehtang, AbbysMom, LogansDad: Thank you all for your advice! Before the bladder surgery, Elv didn't have a problem with taking pills.  When the vet put him on Clavamox for a possible UTI, he ate the pocket pills.  He really liked them.  I think that he got sick of the taste of the pocket pills, so I switched to cheese, some peanut butter, and thin slices of deli meat for him to take his pills. Last Tuesday, Elv had his bladder surgery.  He refused to eat anything, including his hidden pills, for 6 days. Finally, he began to have his normal appetite on Sunday morning and today (he took his AM pills). Hopefully, I will wean him off the mirtazapine, so he'll only have to take it during his chemo treatment.  I know that Elv will not want to eat during those times. LogansDad, thanks for letting me know what to expect during chemo and the stomach acid issue.  I want Elv to take Pepcid or Prilosec.  Does he need to take it at the same time with the piroxicam?  Before or after a meal? (I will ask the vet to OK the acid neutralizer.) Also, LogansDad, do you have any opinion of Apocaps and the Immunity Boost with Transfer Factor.  When I found out about Elv's bladder tumor, he wanted him to have something while I was prepping for possible surgery and chemo.  Dr. Dressler is known as the Cancer Vet and markets Apocaps and Immunity Boost w/TF.  He also has a book, The Dog Cancer Surivival Guide. Next week, Elv will have his sutures removed and will have his liver values measured again.  Instead of OTC milk thistle (3X 175mg) and SAMe (200mg), he now has to take Denamarin. The vet thinks that Elv's heart murmur is higher than Grade 2, so he will have to be put on more medication.  Elv has a appointment with the cardiologist on Wednesday.  On Saturday night, when I was trying to feel him, I was thisclose to giving up.  I felt that I tried everything and anything, and it wouldn't matter because he wouldn't cooperate.  The 3 days after his surgery, I was taking him outside every 2 hours for his urine leak.  I was exhausted, and it still didn't matter how much work because it was still contingent on Elv.  And he wasn't helping me. One positive is that Elv is starting his walk routine again, which was cleared by the vet.  He walked 1.5 miles in 2 hours on Sunday. Thank you again for your response.       It's good to hear that some dogs have benefited greatly from their chemo sessions, with few, if any side effects.  All dogs (as with humans) are individuals and present as individuals when taking meds and supplements. It's imperative that regular bloods are carried out to monitor white blood cell count, when having chemo.  White BCs can take a bit of a hammering with chemo - I'm sure your oncologist will advise accordingly. Some chemo drugs have less negative impact on kidneys than others (vinblastine is quite 'kind' to kidneys). If at all poss (sometimes it isn't), I would suggest getting Elv used to one particular drug before introducing another.  If starting all together and side effects begin, it can be difficult to see what drug is causing what, without stopping all of them and re-starting one at a time.  As for the stomach protectant (Prilosec, etc.)I'd suggest starting a few days before the NSAID. On an ongoing basis, I always gave the omeprazole in the morning and the NSAID immediately following breakfast (couple of hours later). Prilosec(and Pepcid and Zantac) can be given with or without food. - whichever suits. I have heard of Apopcaps.  I would be very careful in using this together with any NSAID. From what I understand, the dosage of one or the other would need to be reduced. e.g. not giving a full dose of an NSAID if also giving Apopcaps.  Apopcaps may well  be a very good supplemenyt, but I try to avoid giving any supp if one then has to 'juggle' the dosage of drugs (and vice versa).  Even Susan Ettinger (oncologist) the 'co-author' of the Dog Cancer Survival Guide is guarded against using both.  I believe that there are some very good supplements out there and Apopcaps isn't one that I have chosen to use.   I now aim to use supplements where there has been strong evidence of use against bladder cancer cells, especially in vivo.As for the K9 Immunity and the Transfer Factor, I have read good reports, but again, I prefer to use supps that have shown some efficacy against bladder cancer cells. This is only my personal opinion. We now use AHCC and salvestrols with Logan (plus, longstanding use of high levels of EPA/DHA in fish or krill oils).  Both the AHCC and salvestrols have been thoroughly researched (\admittedly not, double-blind studies, etc, which are prohibitively expensive, but strongly researched nonetheless).  If you'd like to know more about either, please let me know.  I believe Logan has ceratinly been far more energetic and his appetite is far better since being on both. As for their affect on the TCC, time will tell.  however, he is continuing to urinate very strongly without any blood. Let me know if I can be of any further help.  And, just to confirm - I'm not a vet. LogansDad Tue, 30 Apr 2013 00:00:00 GMT Thank you Baileysmom. I will keep her on the Pepcid since it seems to be working. I just want to make sure I am doing the best for her. Holly :-) LizziesMommy Mon, 29 Apr 2013 00:00:00 GMT On Apr 29, 2013 4:47 PM ElvWestie wrote: Cathtalk, Slomokat, Mehtang, AbbysMom, LogansDad: Thank you all for your advice! Before the bladder surgery, Elv didn't have a problem with taking pills.  When the vet put him on Clavamox for a possible UTI, he ate the pocket pills.  He really liked them.  I think that he got sick of the taste of the pocket pills, so I switched to cheese, some peanut butter, and thin slices of deli meat for him to take his pills. Last Tuesday, Elv had his bladder surgery.  He refused to eat anything, including his hidden pills, for 6 days. Finally, he began to have his normal appetite on Sunday morning and today (he took his AM pills). Hopefully, I will wean him off the mirtazapine, so he'll only have to take it during his chemo treatment.  I know that Elv will not want to eat during those times. LogansDad, thanks for letting me know what to expect during chemo and the stomach acid issue.  I want Elv to take Pepcid or Prilosec.  Does he need to take it at the same time with the piroxicam?  Before or after a meal? (I will ask the vet to OK the acid neutralizer.) Also, LogansDad, do you have any opinion of Apocaps and the Immunity Boost with Transfer Factor.  When I found out about Elv's bladder tumor, he wanted him to have something while I was prepping for possible surgery and chemo.  Dr. Dressler is known as the Cancer Vet and markets Apocaps and Immunity Boost w/TF.  He also has a book, The Dog Cancer Surivival Guide. Next week, Elv will have his sutures removed and will have his liver values measured again.  Instead of OTC milk thistle (3X 175mg) and SAMe (200mg), he now has to take Denamarin. The vet thinks that Elv's heart murmur is higher than Grade 2, so he will have to be put on more medication.  Elv has a appointment with the cardiologist on Wednesday.  On Saturday night, when I was trying to feel him, I was thisclose to giving up.  I felt that I tried everything and anything, and it wouldn't matter because he wouldn't cooperate.  The 3 days after his surgery, I was taking him outside every 2 hours for his urine leak.  I was exhausted, and it still didn't matter how much work because it was still contingent on Elv.  And he wasn't helping me. One positive is that Elv is starting his walk routine again, which was cleared by the vet.  He walked 1.5 miles in 2 hours on Sunday. Thank you again for your response.       Hi, I am happy that  Elv is coming around. You are definitely on the right track with Dr. Dressler's book. We found it late in the game and were already into our own way of doing things.  I had already found most of the info on the internet and was already using it to our advantage. Chica was on misoprostol since the morning before she popped her first Piroxicam capsule and never had a problem with the NSAID for three years, five months.  I think that is the most important piece of information that I ferreted out of my internet search within the first 3 days of Chicas diagnosis.  I would give it to her again in a heartbeat. We never used Apocaps, BUT we did use K-9 Immunity and Transfer Factor (by Alhoa Medicinals), also ProZyme, Salmon Oil (high in Omega 3) and curcumin.  We tried to keep the supplements to a minimum (she hated taking a lot of pills and her meds came first in line...supplements second).  We shopped for her food with optimal nutrients in mind sticking to organic and choosing coldwater sockeye salmon for one of her protien sources.  It's a hard road to navigate, trying to find the way "we" want to approach this horrible disease, but we finally find our way and do the best we can muddling through all the information at hand.  Some things work for some, all things do not work for all...that's what I have noticed.  You will find Elv's "things"...when you do, use them to your advantage. I would also choose the chemo again.  Chica only had a down day at the nadir (low point for blood counts, she was very lethargic), when on chemo, and we worked through that with oncology's help.  She never was nauseous (although they sent home antinausea meds) when she was on.  I believe the best one (the one that we got the best result from) was vinblastine.  It kept Chica's TCC stable for many years (even after stopping it). Keep positive, be persistant, get into a routine with Elv and stick to it, or as close as possible even if he is having a down day or time. ChicasMomForever, Lynn     ChicasMom Mon, 29 Apr 2013 00:00:00 GMT Lizzie's mom-- I would stay with the Pepcid if you haven't had any problems with it.  One of the doctors switched Bailey to the Prilosec and she had a lot of cramping and stomach upset with it.  There is also sucralfate or misoprostol.  Sucralfate is an additional buffer and misoprostol can build up the stomach lining.  But again there can be side effects.  We tried the misoprostol but we did it at the same time with the Prilosec so we're not 100 percent sure which one caused the issues. Baileysmom97 Mon, 29 Apr 2013 00:00:00 GMT Elvwestie, I've been giving Lizzie 10mg of Pepcid 2x a day. I give her 1 between 1PM-2PM. 20 minutes later, I feed her her larger meal and give her 5mg of Piroxicam about 10 minutes later. At night, I give her another Pedcid and follow it with a small meal. She hasn't had any side effects yet and it's been 3 weeks. I do have Prilosec and am wondering if I should put her on that instead. As for Chemo, it isn't an option financially for us and Lizzie is a very high strung, nervous dog so I couldn't put her through that. I was feeling a little guilty but I finally had the nerve to start reading through this entire thread and I don't think I would give her the chemo even if we could afford it.  If you haven't read through this whole board, when you are feeling up to it, maybe read through it and it may answer some of your questions. I hope you can get Elv to start eating. We've been giving lizzie protein (chicken, hamburger, steak) mixed in with a litle of her hard food. I give her the Piroxicam in a piece of melted cheese (I was finding pieces she spit out before). I read people give their dogs veggies as well and may start that too.   Good luck!! :-) LizziesMommy Mon, 29 Apr 2013 00:00:00 GMT Cathtalk, Slomokat, Mehtang, AbbysMom, LogansDad: Thank you all for your advice! Before the bladder surgery, Elv didn't have a problem with taking pills.  When the vet put him on Clavamox for a possible UTI, he ate the pocket pills.  He really liked them.  I think that he got sick of the taste of the pocket pills, so I switched to cheese, some peanut butter, and thin slices of deli meat for him to take his pills. Last Tuesday, Elv had his bladder surgery.  He refused to eat anything, including his hidden pills, for 6 days. Finally, he began to have his normal appetite on Sunday morning and today (he took his AM pills). Hopefully, I will wean him off the mirtazapine, so he'll only have to take it during his chemo treatment.  I know that Elv will not want to eat during those times. LogansDad, thanks for letting me know what to expect during chemo and the stomach acid issue.  I want Elv to take Pepcid or Prilosec.  Does he need to take it at the same time with the piroxicam?  Before or after a meal? (I will ask the vet to OK the acid neutralizer.) Also, LogansDad, do you have any opinion of Apocaps and the Immunity Boost with Transfer Factor.  When I found out about Elv's bladder tumor, he wanted him to have something while I was prepping for possible surgery and chemo.  Dr. Dressler is known as the Cancer Vet and markets Apocaps and Immunity Boost w/TF.  He also has a book, The Dog Cancer Surivival Guide. Next week, Elv will have his sutures removed and will have his liver values measured again.  Instead of OTC milk thistle (3X 175mg) and SAMe (200mg), he now has to take Denamarin. The vet thinks that Elv's heart murmur is higher than Grade 2, so he will have to be put on more medication.  Elv has a appointment with the cardiologist on Wednesday.  On Saturday night, when I was trying to feel him, I was thisclose to giving up.  I felt that I tried everything and anything, and it wouldn't matter because he wouldn't cooperate.  The 3 days after his surgery, I was taking him outside every 2 hours for his urine leak.  I was exhausted, and it still didn't matter how much work because it was still contingent on Elv.  And he wasn't helping me. One positive is that Elv is starting his walk routine again, which was cleared by the vet.  He walked 1.5 miles in 2 hours on Sunday. Thank you again for your response.        ElvWestie Mon, 29 Apr 2013 00:00:00 GMT I concur with a lot of what's been said - including that you're doing a wonderful job with Elv and trying to do all you can! NSAIDs (non-steroidal anti-inflammatories), inc Piroxicam, do have a habit of causing side effects, although it's true to say that some dogs tolerate them more than others. they can cause (among other things), gastrointestinal probs (inc blood in bowel movements), diarrhoea, nausea, INAPPETANCE, neurological probs, etc. Some oncologists prefer the use of Previcox, as they believe it may have less side effects - I'm not 100% certain how true this is.  If using (and they can and do have their place in 'treating' TCC through their anti-inflammatory action and anti-tumour activity) please ensure you use an appropriate stomach protectant. Famotidine (Pepcid AC) and ranitidine (Zantac) can work, but the preferred option is omeprazole (Prilosec). Just to note, that these aren't without their own side effects, too, WHICH CAN ALSO INC INAPPETANCE And (which I understand could be a current problem) they must be given following a meal-size quantity of food.  Dosage of any NSAID is also key. Sticking to the mg/kg (or mg/pound) option is usually a good starting point.  Some NSAID tabs have a wide suggested dose range, e.g. Previcox - one 227mg tab for dogs ranging from around 22kg to around 40kg, although, at the same time advising 5mg/kg!! Mirtazapine does have some anti-nausea qualities, although it isn't strictly speaking a true anti-emetic. Cerenia (unless giving by injection, tab has to be given with a small meal or snack, otherwise it can cause vomiting)and ondansetron can be far more effective. Mirtazapine usually 'comes into its own' as an appetite stimulant, which is in fact one of the drug's side effects. It is isn't always easy to reach the dosage you need with the tablet form of mirtazapine (one 15mg tab is scored to be divided into  2x 7.5mg). Some dogs will need a dose that isn't either 15 or 7.5mg - trying to cut into quarters can be a nightmare! There is a liquid form, which can be gicen in more accurate doses. Please note, mirtazapine can also produce its own side effects - plse google to find out more. Trying to give the meds when Elv won't eat and can be a littel 'snappy' must be very difficult for you.Contro llling any nausea and overcoming any reluctance to eat is key to resolving this (sorry for stating the obvious). changing the dosage of the NSAID or changing to another, may help. Introducing an anti-nausea med may also help. Have you tried liver sausage (sometimes known as liverwurst) to wrap the meds in? As for chemo, Logan had this for almost a year.  We started with iv mitoxantrone (initial chemo med of choice with TCC) and have also morwe recently used vinblastine. there are others being used: gemcitibine, vinorelbine, etc.   They can work beytter in conjunction with NSAIDs.  Initially, the mitox worked (shrank tumour in trigone area/urethra by around 50%) then it bwecame ineffective and the tumour grew and others appesared and we swapped to vinblastine which appeared to keep the masses stable.  However, we have decided to stop the chemo (for a variety of reasons) and now opt for a more holistic and less toxic approach, inc the use of salvestrols and AHCC (we do use other supps, too).  Whether or not to use chemo is purely a personal choice. Logan may not have been here now if it wasn't for chemo; who knows, but we felt enough was enough given how the whole chemo experience affected him (physically and emotionally). Please do keep an eye on Elv's kidney values if opting for chemo.  And of course, consult with your vet/oncologist - I'm neither! Please keep us updated - and remember you're not alone even if it can feel like it at times. Best wishes Garry and Logan LogansDad Mon, 29 Apr 2013 00:00:00 GMT Kathy that is fantastic that Slice is eating. I wish you all the best. Elv's Mom, believe it ornot Abby would only take her pills in pill pockets. Tried everything else. You can also try baby food to get Elv to eat. It's not easybuthang in there. Glad you had a good diagnosis. Lisa Abbysmom5809 Sun, 28 Apr 2013 00:00:00 GMT Thank you Cathtalk. Yes, I was so devastated. I still am, but after 8 straight days of crying, I realized it was no good for Lizzie and I needed to enjoy the days I have left with her. Lizzie still strains a bit. She is going little streams now most of the time. Hasn't had bleeding yet. I monitor her every time she goes out. She is still getting up a few times a night. I am exhausted, but wouldn't trade a day of it for anything. She is my princess now and I want to make every minute of the rest of her life perfect. The only sad part is she gets very upset when I leave the house. I work from home and she has gotten very attached to me :-(. LizziesMommy Sun, 28 Apr 2013 00:00:00 GMT Hi Lizzie Bear's mom, Glad to hear she's doing well and active -- and tolerating the piroxicam too.  I remember when you posted about her prognosis and how anguished you sounded. Keeping her on an NSAID helps and does add months on -- my Meg had an easier time with her bladder once we started her on one and the blood disappeared from her urine, thank goodness, as well as the straining.  It required some trial and error to figure out what her stomach could tolerate.  Lizzie will let you know what works, too!     Cathtalk Sun, 28 Apr 2013 00:00:00 GMT My Lizzie is only getting 2 10mg Pedpids per day and 2 small meals. She gets her Piroxicam after the first meal. She still has her appetite and is still active. The Piroxicam seems to be working as 3 weeks ago, she could barely pee. She does struggle to poop though but it's normal. I wanted to add some probiotics but my husband feels that since she is doing well, don't change anything. LizziesMommy Sun, 28 Apr 2013 00:00:00 GMT I'm sorry to hear of your loss with Abby, Lisa.  I think my earlier post didn't go through.  I hope she's in a better, happier place with your other loved ones! Cathtalk Sun, 28 Apr 2013 00:00:00 GMT Good to hear about Slice having his appetite and that he's still with you, Kathy!  It soiunds like you've found out what works. A dog's appetite is one of the surest things and it's wonderfully reassuring when it comes back.  I think my scotties were eating better than I was at times -- homecooked veggies, chicken, broths, yogurt, etc! Cathy Cathtalk Sun, 28 Apr 2013 00:00:00 GMT Hi to you.  Fantastic that Elv is 16 -- he must have a combination of great things in his life, including you. It's good to hear that he ate something and on his own.  He should be eating more, though, so you are right to be worried.  Is it possible the anesthaesia may have lingering effects? I really also would look carefully at the meds to see if there are possible side effects that would be causing his appetite to diminish at this point. I looked over the meds you listed that Elv is on to see if any of them might be causing him nausea, especially any that you just introduced recently.  I'd worry about the piroxicam.  My female scottie Meg (at 28lbs) had a hard time taking that drug -- she suffered serious nausea and vomiting and some allergic reactions/skin rashes.  Others here will also tell you some of their canine companions also had some trouble.  I switched Meg to Derammaxx (if you can find it) and the nausea declined. Others here have had their canine companions on previcoxx, metacam, etc. They are all NSAIDs.  You may wish to give Elv a break of a few days from the piroxicam or switch it with another NSAID.  Talk to your vet. However I also prepped Meg's stomach before hand with pepcid (two 30 mg tablets 1/2 hour before meal), plus sucralfate/carafate (1/2 gram tablet before meal, crushed and diluted w/ 1-2 mgs of water, one hour before meals). I had to adminster the carafate by syringe. I also gave Meg and Darnley Cerenia for nausea, too, now and then. I know many here recommend miratazapine to help nausea.  It may possibly, possibly produce some side effects.  Do a bit more reading on it. My two scotties also had elevated liver enzymes and were taking Sam-e/denamarin as a supplement. The Sam-e/ denamarin did not seem to give their stomachs any trouble. YOu may also be able to get liquid medicines with chicken/beef flavors -- it may help somewhat.    Cathtalk Sun, 28 Apr 2013 00:00:00 GMT Bed and Bath has a giant plastic dropper that we use on Slice. I crush the pills mix with fluid and do a quick quiet down his throat. When he would not eat anything, I ended up giving him green super food paste from the herb store. It was at a dead end, and it seem to do the trick nutrition wise. Also he would occasionally like ice cream and nitrate free hit dogs (trader joes). We had to back down on the medd as they destroyed his kidneys. Piroxicam being the hardest on him. Be. Sure to prep his stomach with Pepcid before giving the piroxicam. Great news for Slice, he is now eating without mirtazapine. Hope things get better for you and Elv. Kathy slomokat Sun, 28 Apr 2013 00:00:00 GMT wow you are doing alot for him.  You give him alot of medicine and sometimes i wonder if just feels awful and he can't eat... i have said that with Pino when he absolutely refuses.  i respect that because otherwise he would eat..he just feels really bad.. try liquid forms and if he will let you syringe it and feed it to him through the pocket of his mouth.. I have his meds in liquid form too although they taste so bad nothing covers the flavour and he spits it out all over the place.  so i syringe some milk (he can take both lactose free and normal) and call it aday... just love him.. Elv will tell you what Elv can tolerate... Elv sounds beautifully stubborn and adorable.. god bless him.. mehtanp Sun, 28 Apr 2013 00:00:00 GMT I am new to this board.  My Westie Elv is 16 years old. He had blood in his urine, which I noticed in March/April 2013.  He's had UTIs in the past, so the vet prescribed an antibiotic.  After the treatment, I noticed that he still had blood in his urine.  So he had an x-ray, which didn't show bladder stones.  Then, he had an ultrasound for possible tumors. There was a tumor that was away from the urethra (trigone area) and was along the bladder wall , so it was operable.  He had surgery on April 23, 2013, so I'm waiting for the biopsy.  I will have to assume that it's TCC, so he already has been prescribed piroxicam, 3 mg capsule/once daily.  The good news is surgery was possible, and there was no sign of metastisis in the lungs (chest x-ray), or in the abdomen area, or the prostrate.  My Westie has always been a picky eater.  He hasn't eaten since Monday, April 22, the night before surgery.   I called the vet, and on Saturday, April 27, he was given a shot of Cerenia and I asked for mirtazapine.  My Westie can be a biter, so it was difficult to give the pill to him.  After the mirtazapine, he probably ate 20% of what he would normally eat.  Later in the evening on Saturday, I offered the piroxicam, which was wrapped in roast beef.  He wouldn't eat.  Right now, it's frustrating, because he has a lot of pills.  He won't eat.  I do have a fear that he'd rather pass to the Bridge than eat.  Any help with getting my dog to eat or take his pills (he's a biter) would be greatly! appreciated.  Today, I just lost it because I felt as if I have done all this work to help him, but it's not going to matter because Elv will NOT take his pills or eat.  He's going to be in a worst position when he has chemo.  Or if the piroxicam affects his intestines or causes stomach ulcers. Elv stats: 16 year old Westie, DOB Nov. 20, 1996; very healthy; still takes 2 hour walks daily; heart murmur from mitral valve, stage 2; 30% back flow seen from the doppler; elevated liver enzymes; he was taking 200 mg SAM-e and 175 mg milk thistle, 3X/daily Pills he will have to take: piroxicam, 3 mg capsule daily; miratazapine, 1/2 tab as needed (probably will need during chemo treatment) Denamarin (instead of SAM-e and milk thistle) I am going to include these pills as well: Apocaps, 5X daily K9 Immunity Boost with Transfer Factor              ElvWestie Sun, 28 Apr 2013 00:00:00 GMT Thanks to all for your kind words. My husband had given me a locket a few years ago with Molly and Abby. We are going to make a shutterfly book for her. Everything happened for a reason yesterday. We chose to go to the ermergency clinic instead of our regular vet since they could do an ultrasound if she needed it. We got there and were waiting in the room when she started having the seizures. The vet on duty was the Veternanrian Neurologist. Within seconds he had her. The seizure was over before he needed to intervene. He ran her blood work. By thursday, her kidneys were failing, on Monday they were fine. Her blood work showed no reason to have caused the seizure. He thought she either had a blood blot or the cancer had spread to her brain. That made the decision for us. We didn't want her to suffer. We have no doubt especially since we had a Neurologist tell us. We were blessed to have her in our lives. She is with a whole pack of our family animals and with my Dad, Sister, and my husbands Mom. She is chasing rabbitts and enjoying her peace. When we got home, Molly, our terrior mix, had decided to find a patch dandelions. She came up to us with her face covered and smiling. We needed that. Abbysmom5809 Fri, 26 Apr 2013 00:00:00 GMT I'm so very sorry to hear about Abbey. I am keeping you in my thoughts and prayers during this very difficult time. Love, Nita Nita Fri, 26 Apr 2013 00:00:00 GMT Dear Lisa I am so truly sorry to hear this. Abby was clearly loved so very dearly by you. You have sent her on to another part of her journey and will meet again. I will light a candle for her..... Garry and Loganx LogansDad Fri, 26 Apr 2013 00:00:00 GMT I am heartbroken to hear your news.  A lot of us have gone through this and it just plain stinks.   Try to make peace with yourself in knowing that you did all you could to keep her going and keep her comfortable.  I think the one universal for all of us is that we do not want them to suffer.   Cherish her memories and the happy times you spent together.   I managed to get some comfort by putting together a Shutterfly album of Bailey.  One other thing that has helped me...I got a photo pendant made of one of my favorite photos and this makes me feel like she's right there with me. My best to you at this difficult time, Karin  Baileysmom97 Fri, 26 Apr 2013 00:00:00 GMT So Sorry!!! My eyes are filled with tears. I know that once you make the decision, you do know its the right time.   Abby knows you loved her, and gave her a great life. Still I am saden by your news, and wish you many happy Abby memories. KAthy, and Slice slomokat Fri, 26 Apr 2013 00:00:00 GMT Every time I read a post like this my heart breaks. You did the right thing and she loved you til the end. Out time with these animals is never long enough. It's so hard to say goodbye. It's been 10 months since we lost Shelby and we still miss her. But it will get easier on you. So just try to remember all the most wonderful things about your time together and not her fight at the end. Best wishes to you. Sallie Shelbysmom2 Thu, 25 Apr 2013 00:00:00 GMT On Apr 25, 2013 5:17 PM Abbysmom5809 wrote: Aby lost her fight today. She was vomiting and we when took her in for fluids she had a seizure. Her kidneys were failing so we felt it was time to give her peace. She was the best and she fout hard. Thank you to everyone for all your help.Lisa, I am so so so sorry for your loss. I know you lost a piece of your heart today :-( It is so heartbreaking to watch our babies like this. Just know that you gave her a wonderful life and you will meet her again one day. Abby will be there waiting for you :-(   <3 Holly LizziesMommy Thu, 25 Apr 2013 00:00:00 GMT On Apr 25, 2013 5:17 PM Abbysmom5809 wrote: Aby lost her fight today. She was vomiting and we when took her in for fluids she had a seizure. Her kidneys were failing so we felt it was time to give her peace. She was the best and she fout hard. Thank you to everyone for all your help.Oh Lisa :( I am so sorry.  You did everything that you could to extend Abby's life with utmost thought of quality. I know you are hurting right now...I am hurting for you and with you.  I also know how hard it is to make that last ultimate decision...but you made it with only Abby in mind.  You BOTH fought hard, and Abby knew how much you loved her.  Abby cannot thank you for making the right decision for her, but I can...for her.  "Thank you!  I love you. Make a special place in your mind and heart for me, remember me always." I also wish you the peace you deserve...the peace of knowing that you did your best under very difficult circumstances.  When we first entered into this fight with TCC...we knew from the very start what the outcome would be...but we fought with all we had anyway.  Yes......we all need that peace of knowing...... ChicasMomForever, Lynn ChicasMom Thu, 25 Apr 2013 00:00:00 GMT Aby lost her fight today. She was vomiting and we when took her in for fluids she had a seizure. Her kidneys were failing so we felt it was time to give her peace. She was the best and she fout hard. Thank you to everyone for all your help. Abbysmom5809 Thu, 25 Apr 2013 00:00:00 GMT yes, mirtazapine is also what we use with our dog Pino.  He even gained a pound or two....we live in ontario canada.  Pino a ridgeback mix was diagnosed in NOvember with TCC.  He is doing pretty good.  He is still peeing (his first couple of attempts are good, then he dribbles).  He is incontinent alot of the times. I chase after him swiffering the dribbles.  He is 10 yrs old.  I wanted to see if a stent might help him but the cost here is astonomical (4-5K) and with very poor results.   We have done well with metacam, baytril (150mg), mirtazpine (1/2 tab) and petalive products of ccaps and pro pet drops... we also have keep him on low residue metacal fibre response food ..about 2/1/2 cps a day.  with lots of treats....ie liverwurst and/mortadella.... We have tramadol but havent had to use it so far... We hope to have him atleast through the summer so I can enjoy him rolling in the grass, and basking in the sun in the backyard--he loves that especially after his bath, with a bone...i know he is smiling..and just loving life... he is our 'lovebug'... mehtanp Wed, 24 Apr 2013 00:00:00 GMT Hi Lisa-- One thing to note, Mirtazapine also stimulates the appetite where I think Cerenia is only an anti nausea.  Bailey was a bottomless pit on the Mirtazapine. Karin Baileysmom97 Tue, 23 Apr 2013 00:00:00 GMT On Apr 23, 2013 12:31 AM Abbysmom5809 wrote: So our vet feels Abby was given to high dose clavamox. Took her into our regular vet, she gave her fluid subq, and cerenia shot. She also gave us cerenia pills for tomorrow. Once Abby is stable we will give denamarin, really strong milk thistle. She has slept most of the day. We go back tomorrow to our vet. She has cut the clavamox dose in half for now. We may end up with 3/4 the dose she was taking. I'll let you all know.Abbys mom- your day sounds very familiar. I think Slice went through this a week or two ago. Here is what worked in our house... After the cerenia shot, and fluids, his stomach seem to settle.  The oncologist said to use the cereniaonly  as needed, as Slice has bigger issues with his kidneys.  Also he suggested I only use the clavamoxfor a few days, instead of the usual week or two. ( slice had a cough for awhile,but it seems to have gone away with three days of antiboitics). Not sure how far along Abby is in her treatment, or how well her kidneys are doing,but dose her sparingly. Slice seems to be doing really well since the doc gave him " a week maybe two".  He is on Mirtazapine, pepcid, sub q fluids 2x a day, and a whole slew of holistic stuff. Hope this helps in some way. Kathy slomokat Tue, 23 Apr 2013 00:00:00 GMT So our vet feels Abby was given to high dose clavamox. Took her into our regular vet, she gave her fluid subq, and cerenia shot. She also gave us cerenia pills for tomorrow. Once Abby is stable we will give denamarin, really strong milk thistle. She has slept most of the day. We go back tomorrow to our vet. She has cut the clavamox dose in half for now. We may end up with 3/4 the dose she was taking. I'll let you all know. Abbysmom5809 Tue, 23 Apr 2013 00:00:00 GMT Thanks Karen. I am orderingher milk thistle now. I will ask our vet the mirtazapine. Lisa Abbysmom5809 Sun, 21 Apr 2013 00:00:00 GMT Hi Lisa-- Don't know if you've got her on Mirtazipine (an anti nausea) but it worked wonders with Bailey.  Also, for the liver issues, get milk thistle as fast as you can.  It comes in liquid or powder but I think liquid may be better.  I can't remember which online site I got it at, but there is some made specifically for dogs, it's bacon flavored!  Bailey had some issues with the liver enzymes and after she was on the milk thistle, her next bloodwork showed her liver values were completely normal.  The milk thistle helps to detoxify the liver.  I would highly recommend this to all of the dogs on meds.  You can also get it at a vitamin shop or GNC in the meantime. Karin Baileysmom97 Sun, 21 Apr 2013 00:00:00 GMT Abby used her potty patch for the first time today which helps us rest easier. We put in our bathroom for her so if for exhaustion reasons we didn't wake up at night to let her out, she could still go and would be OK. Who says you can't teach an old dog new tricks? Got her to eat some today. Thanks for all the great suggestions. My husband got her greek coffee flvored yogart. You can't put a coffee cup near Abby without protecting it, Ifound that out right after we got her and she drank mine as fast as she could. We don't normally give her coffee but if she'll eat the yogart, who cares. She ate the baby food chicken sausages. Thanks for the great suggestions, Lisa Abbysmom5809 Sun, 21 Apr 2013 00:00:00 GMT Thanks to all for posting. Abby is having a hard time. She still has the original UTI from Februaury. She was put on cipro after the stent placement but, of course, it is resistant to that so she is back on clavanox. She doesn't want to eat. I made her a small hamburger and got her to eat that before the piroxicam. Going to try the other suggestions on this site and check with her vet on Monday. I am hoping her liver and creatinine values are still stable. Her liver enzymes were increased while her creatinine was actually below the normal range and bun was great. It was done on March 5, so hopefully she is not eating because of the antibiotics. Abbysmom5809 Sun, 21 Apr 2013 00:00:00 GMT On Apr 09, 2013 6:29 PM LizziesMommy wrote: Thank you all so much! I was so in the dark with this. So devastated. I've been crying for 7 days straight. I am trying to be strong in front of Lizzie but it's been really hard. I started giving her Zantac 2x a day and made sure she ate dinner last night before her piroxicam. 6PM tonight will be exactly 3 days since she started the piroxicam. She went from not being able to go to the bathroom at all on Sat, to going in small amounts (continuous drops) now. She is somewhat active (she was nuts before). She eats and drinks. Every time I take her out, my heart stops in fear I won't see anything coming out. I know you've all been there. This week is been so hard because I am trying to have hope, but don't know what I'll do if the piroxicam doesn't help her. I am so overwelmed with all the info so I must ask, do you get the vitamins/holistic meds from your vets, Whole Foods, online? I am in such fear that her days are numbered and want to get something as soon as possible. Abbysmom, Slicesmom, Andysmom, Logansdad and Baileysmom, I'm so sorry you are facing this with your babies :-(. Thank you all so much for helping me through this awful tragedy. Logansdad, I am praying for miracles that she gets through the next week. I will be thrilled if I can have her another 2-3 months. Longer would be great, but I just want her here so she can enjoy her life without suffering. :-(Dear LizziesMommy, I get all my supps online, can't get any of this stuff in Australia & the vet that diagnosed him doesn't believe in alternative therapy so I'm his Doctor. Deb tryeverything Wed, 10 Apr 2013 00:00:00 GMT On Apr 09, 2013 1:21 PM LogansDad wrote: so good to hear about another dog living with TCC that's doing so very well... they are out there! Andy's v fortunate to have you. logan's "my life's work" too Deb.  I'm with him almost 24/7. he's never left along (my partner's here if i have to pop out). he is having some inappetance probs at the mo - maybe he doesn't like my cooking! and probs with sleep at night, but he does have some very playful times.. he also has chronic kidney issues but nothing too severe at this stage.. I was v interested in seeing that Andy has a raw diet.  Given Logan's weight loss and becoming so difficult to feed (yesterday i reluctantly restared to syringe feed him his food - roast duck, sticky rice and veg..). Has Andy always followed a raw diet?  We have considered, but i'm paranoid about possibility of salmonella, e-coli, etc. with a dog with a compromised immune system (even more so as he is receiving chemo).  we did buy some high end raw food (green beef tripe with veg) but it sits in the freezer as i don't want to put him at any risk?!?  i've posted on a few forums but have had v ltd response.  Our vet is against raw for Logan (to be predicted i suppose!).  however, even our homeopathic vet that feeds his own dogs raw, wasn't sure it was right for Logan.  I'm still open to anyhting at this stage. if he doesn't want to eat what i'm cooking/offering him, we'll soon run out of options. Would really appreciate your own expoeriences of feeding raw to a dog living with cancer. also i'll be checking out the supps Andy receives.  we did have Logan on a wife array of supps, but stopped most things when he went through a really badpatch a few weeks ago and it became too stressful for him to continue to receive stuff via pill, potion and powder (could never mix with his food, but as he wasn't really eating it became a nightmare..) As you can see, Logan was also dx  May 2012 (1st), so they've got something else in common.. i want whatever time left Logan has  to be happy and as healthy as poss, as i know you do for Andy. look forwardt to hearing from you. garry and Logan Hey Garry, I know the kind of emotions you feel, sometimes you think you've got IT, then it seems like the more info you read the more you don't know anything but we keep going. I've defined & redefined Andys supps over the 12mths but I've always stuck to a raw meat diet, I guess it just worked for him. I go to a butcher that sources his own meat not commercial like the supermarkets. His beef is grass fed, but I do mix it with chicken that is cooked, I like to give half & half & I keep the chicken broth & add some to each meal so as it's not to dry to mix in the supps. I've recently put him on BioSuperfood (just google this & it will come up) so he doesn't need so many vitamins. I'm still giving him PolyMVA, RM-10 Ultra, Salvestrol Platinum & of course DHA omega 3 (Chia oil) Oh! & by the way, it's ground beef that I mix with steamed v-gs, he never gets sick of this, I get enough for 2wks & freeze in daily packs but cook enough chicken to last a few days in the fridge, Just cut it up as you need it to mix with the meat. Keep going Garry we are with you, it really changes your life doesn't it. It's funny, when I find out something new my hope is renewed all over again. What a journey. God Bless you & Logan Deb tryeverything Wed, 10 Apr 2013 00:00:00 GMT Not sure if you have seen any of the earlier post in this thread but there was reference to a procedure called endoscopic guided laser ablation. There are only a few places that do it at this point. I used vet specialty in Chicago. My Reese was diagnosed with bladder TCC in early January. She was not doing well at all only drips when she peed and there was blood, prognoses was very bad. We went to the oncologist and he began the chemo and proxicam regiment. As a reference of this procedure from her regular vet I scoured for information and it was very limited. Then I came across Veterinary Specialty Centers in Chicago. I am from Cleveland, OH. We scheduled the procedure and took her to Chicago. It was an overnight stay and we brought her home the next day. She was a little lethargic from the surgery meds but when I took her out at a rest stop to try and go I almost cried when I seen a steady solid stream and her legs weren’t shaking as before. The procedure was done February 11th She is still doing great solid stream playful and energetic. Best thing is this procedure is repeatable unlike surgical removal. She is on her final round of chemo and we will do another ultrasound to see what happening. The best thing was it was immediate relief for her. Now the bad… as this is a somewhat new procedure and not widely performed it is expensive. Pricing I’ve seen range from $2800 to $9000.00 in the place in NJ. The Chicago place was in the $2800.00 area but they were absolutely great. We have also gone with home prepared holistic diet, we cook the food as we were worried about preservatives in the store bought meat and we use vegetables and a little no carbs her oncologist has given us a vitamin supplement for that. I know we are battling a relentless foe but for every day we have her happy and living a good quality life I am grateful and we will continue to fight as longs as she is willing ? Rwhiteohio Tue, 09 Apr 2013 00:00:00 GMT I got all the holistic stuff for Bailey online.  It's usually pretty quick shipping.  If you look at page 268 of this thread, Sienna'smom has a regimen which seems to be working for her dog.  If you click on the profile icon, this will bring you to the membership page for each person and you can see all of their previous posts.  Information is your best friend and I think you have to try different things to find what works best. Neoplasene was something we were trying, but didn't have a chance to see if it would really work...Bailey passed away 7 weeks ago, but not from the cancer.  She had the cancer for 2 years and 2 months and was doing really well battling the cancer. If anyone is interested in the Neoplasene, I have almost a full bottle and would be willing to give it to you. Karin Baileysmom97 Tue, 09 Apr 2013 00:00:00 GMT Thank you all so much! I was so in the dark with this. So devastated. I've been crying for 7 days straight. I am trying to be strong in front of Lizzie but it's been really hard. I started giving her Zantac 2x a day and made sure she ate dinner last night before her piroxicam. 6PM tonight will be exactly 3 days since she started the piroxicam. She went from not being able to go to the bathroom at all on Sat, to going in small amounts (continuous drops) now. She is somewhat active (she was nuts before). She eats and drinks. Every time I take her out, my heart stops in fear I won't see anything coming out. I know you've all been there. This week is been so hard because I am trying to have hope, but don't know what I'll do if the piroxicam doesn't help her. I am so overwelmed with all the info so I must ask, do you get the vitamins/holistic meds from your vets, Whole Foods, online? I am in such fear that her days are numbered and want to get something as soon as possible. Abbysmom, Slicesmom, Andysmom, Logansdad and Baileysmom, I'm so sorry you are facing this with your babies :-(. Thank you all so much for helping me through this awful tragedy. Logansdad, I am praying for miracles that she gets through the next week. I will be thrilled if I can have her another 2-3 months. Longer would be great, but I just want her here so she can enjoy her life without suffering. :-( LizziesMommy Tue, 09 Apr 2013 00:00:00 GMT Hi Gary-- One to keep in mind with Logan's kidney issues is that broccoli contains a fair amount of protein.  Bailey was always borderline with the kidney problems as well, so when they got worse I stopped the broccoli.  Just something to keep in mind. Karin Baileysmom97 Tue, 09 Apr 2013 00:00:00 GMT so good to hear about another dog living with TCC that's doing so very well... they are out there! Andy's v fortunate to have you. logan's "my life's work" too Deb.  I'm with him almost 24/7. he's never left along (my partner's here if i have to pop out). he is having some inappetance probs at the mo - maybe he doesn't like my cooking! and probs with sleep at night, but he does have some very playful times.. he also has chronic kidney issues but nothing too severe at this stage.. I was v interested in seeing that Andy has a raw diet.  Given Logan's weight loss and becoming so difficult to feed (yesterday i reluctantly restared to syringe feed him his food - roast duck, sticky rice and veg..). Has Andy always followed a raw diet?  We have considered, but i'm paranoid about possibility of salmonella, e-coli, etc. with a dog with a compromised immune system (even more so as he is receiving chemo).  we did buy some high end raw food (green beef tripe with veg) but it sits in the freezer as i don't want to put him at any risk?!?  i've posted on a few forums but have had v ltd response.  Our vet is against raw for Logan (to be predicted i suppose!).  however, even our homeopathic vet that feeds his own dogs raw, wasn't sure it was right for Logan.  I'm still open to anyhting at this stage. if he doesn't want to eat what i'm cooking/offering him, we'll soon run out of options. Would really appreciate your own expoeriences of feeding raw to a dog living with cancer. also i'll be checking out the supps Andy receives.  we did have Logan on a wife array of supps, but stopped most things when he went through a really badpatch a few weeks ago and it became too stressful for him to continue to receive stuff via pill, potion and powder (could never mix with his food, but as he wasn't really eating it became a nightmare..) As you can see, Logan was also dx  May 2012 (1st), so they've got something else in common.. i want whatever time left Logan has  to be happy and as healthy as poss, as i know you do for Andy. look forwardt to hearing from you. garry and Logan LogansDad Tue, 09 Apr 2013 00:00:00 GMT i meant to say, that Previcox (firocoxib) is apparently better tolerated than piroxicam..less tummy probs. it is also a slective cox 2 inhibitor, so works the same as piroxicaM... LogansDad Tue, 09 Apr 2013 00:00:00 GMT Dear Holly Really sorry to hear about Lizzie Bear's TCC diagnosis. I seem to be hearing of so many dogs being diagnosed with TCC, lately. Firstly, if using, please make sure Lizzie has the piroxicam following a meal. And, as others have said, a tummy protectant is essential.  some have had had success with omeprazole (Prilosec in US), pepcid AC (famotidine) or Zantac (ranitidine). Watch out for any blood in her poo and let your oncologist know if this occurs. This isn't necessarily the end of the road for your girl. Our Logan was dx with TCC (originally in the trigone area and into the urethra and now also in the main bladder) on 1st may 2012. we opted for chemo (mitoxantrone) which did reduce size of the tumour.  the mitox stopped being effective (too few ultrasounds were carried out - something we keep a closer eye on now) and mitox was prob not working for a couple of sessions.... Logan's now receiving another chemo (vinblastine( which appears to be kjeeping the tcc stable. For a variety of reasons, we are now looking at other options for Logan. But, my main point is....Dogs can live longer than the median survival rates that some oncologists regularly quote (some, of course, do noty live as long).  I am not aware of Lizzie's specific details (location and progress of tumour in bladder, urethra, other med conditions,etc.). However, 'median survival period' is, I believe, is a lot longer than 2-3 months. Her emotional state is vitally important (as is yours as you are supporting her)....try to keep positive around her.... Supplement essentials:  omega 3 fish and/or krill oil - high in EPA and DHA............a good quality multivit...good qual probiotic...There are many supplements to chose from..... Diet:  higher in good quality protein..(unless kidney disease with proteinuria) low or no grains.  veggies, especially broccoli (pureed or v lightly steamed). Filtered water. sorry this is brief, but Logan's having a few probs at the mo and i also want to place another post. keep in touch and let us know how lizzie gets on. take care garry and logan.  eng bull terrier.  11yrs 11mths. dx tcc 1 may 2012. kidney disease LogansDad Tue, 09 Apr 2013 00:00:00 GMT Hi Holly, I am not switching Abby to high protein diet as that will cause her liver issues and she already has an enlarged liver. She has had an enlarged liver for years so this is nothing new. She's a tough little dog. She had severe heart worms when we adopted her. It was a rough month while they treated her but she pulled thru that so hopefully we can make it thru this for a long while. We adopted her when she was 4 yrs old. She is now 12. Lisa Abbysmom5809 Tue, 09 Apr 2013 00:00:00 GMT Hi LizziesMommy, Just thought I'd let you know of some holistic supps that I've been using with success. My boy Andy (Maltese-Shitzu) who is 13 now was diagnosed with bladder Tcc last May. I have been using RM-10 Ultra & PeakImmune 4 (MGN3), Salvestrol Platinium & Bio Superfood with a raw food diet with v-gs. So far so good. Hope this helps. I might add that this has become my lifes work. Deb tryeverything Tue, 09 Apr 2013 00:00:00 GMT Lisa, Sorry about the specialist but I am so glad your baby is doing better. Thanks so much for the info. Our vet is the one who stinks and the specialist was wonderful. She knew how upset I was so she called me Sat night with the biopsy results. It only took her a few hours. My vet did bloodwork 3 weeks ago and told me it was ok. I am so furious. Kathy, I'm so sorry about Slice. I am glad he is doing better though. This is just the worst thing ever. I hope the holistic method works for you. I know your heart is breaking. :-( Thank you SO much for telling me about your issue. I am literally freaking out. The vet didn't tell me to feed her first and didn't prescribe anything for the stomach. If I didn't find this sight, I would have never known to feed her first. I just gave her a Zantac (don't have any Pepsid in the house). I am going to buy Pepcid tomorrow morning for her. I can't stop the proxicam because it is the only chance she has to buy some time. She couldn't even use the bathroom Sat before I took her. I convinced myself she wasn't coming home but she wasn't ready to go. She wanted to come home. I made a promise to her that I would never make her leave the house again (she is very high strung and anxious) and I am going to have a mobile vet come when she needs to cross the rainbow bridge. I am so brokenhearted over this but am glad to have met people who know how I am feeling because I think everyone is getting sick of me crying (nonstop). Holly xoxo to every one of you and your babies     LizziesMommy Tue, 09 Apr 2013 00:00:00 GMT Hello Lizzies Mom, Slice is my baby and he was diagnosed a few months ago with TCC. I am learning a lot on this web site. I learned the most after I had given Piroxicam to my baby for 1 month, and then his kidneys pretty much shut down, as did he.   He would not eat, or drink, and did not want ot do anything but sleep.   I asked how to get him to eat, and what to try next, as he seem to be at the end ( or so the vet told me). I belive the Piroxicam ruined his kidneys.  I was not told to prep him with pepcid 30 min before or give him the Sufacate ( sorry cant remember how it is spelled) before giving him his meds. Slice was also on Leucarin at the same time.   We have since stopped all meds, except the ones to get him to eat ( mirtazapine) and the pepcid to settle his stomach.   What we are trying is is the holistic approach, and it seems to be working.  We learned of herbdoc.com from a freind who said it cured his mother of stage 4 breast cancer.     I was out of options, and figured it cannot hurt to try.     Slice is on the 30  day detox program, and I dont know if it is curing anything, but he is eating and drinking, and going outside to pee, and on occasion trotting across the yard.  Last report from the blood work showed high Phosphorus, and stable but bad kidneys at 10.1 creatinin. We will get new lab work done in a few weeks. I hope the piroxicam works for you, but i wouldnt conitune it without reading more on the side effects. Keep me in the loop- Kathy slomokat Tue, 09 Apr 2013 00:00:00 GMT Holly, We got the sucralfate from our vet. It's a prescription. He did say 10 mg of pepcid twice per day if she doesn't cooperate. Abby's tumor is in the neck of the bladder and going down into the urethra. The piroxicam can cause ulcers in her stomach so check into something for it. There is no reason for her to have to extra suffering. Watch for dark stool. We went to a specialist our vet sent us to for the ultrasound. He did a urine cytology but did not start her on any meds. Our vet started Abby on meds before the results came back. Abby blocked on Sunday and we still did not have results back. We rushed her to the emergency hospital where they cathed her. They did biopsies on monday and measured her for the stent. The stent was placed on tuesday. We did not get the cytology results back till late Monday, which was negative. Her biopsies were positive. Our vet was very pleased we had taken to emergency hospital and they did the stent. She was not happy with the specialist she sent us to. As long as Lizzie is doing well, hang in there and enjoy her. Lisa Abbysmom5809 Tue, 09 Apr 2013 00:00:00 GMT Lisa, Thanks for the response. Sorry about Abby. Is hers in the bladder or urethra? They didn't want to put a stent in Lizzie because of the location of her tumor. They said that with the location, she may live 2-3 months (if it works). Before I took her for the procedure on Sat, she could barely go. Now she is going steady drops when she goes. Also, last week she was straining and straining and would stand there forever. Now she comes back to the door. Our vet made us wait over 2 days for the results from the radiologist. We took her to a specialty animal hospital on Fri, and they did the prcedure on Sat. She is still eating and active. They didn't tell us to give her anything for her stomach. I don't think they had much hope. When I brought her in Sat, I thought that would be her last day. I've read that people give their pup Pepsid. Is the Sucraflate slurry available locally or is it best to get it online? Also, did you change her diet? Thanks so much! Holly :-) LizziesMommy Mon, 08 Apr 2013 00:00:00 GMT On Apr 08, 2013 7:27 PM LizziesMommy wrote: Also, I want to add that the vet said that with the piroxicam, she "may" live 2-3 months (if it works). Are there any holistic meds or foods I can add to her diet? I am completely heartbroken. Thank you and I am so sorry for everyone who lost their furbaby to this horrible disease. :-(Hi LizziesMom, We have Abby on Sucraflate slurry 3 times a day. Be sure that Lizzie is on something to protect her stomach from the piroxicam. We had to put a stent in Abby to keep her urethra open and give the piroxicam a chance to work. It has only been a week and half since she got the stent and diagnosis but she has a great stream. From my research Purdue vet school has had some good success with piroxicam and some dogs living a year or more. It appears to really show 3 months after starting the piroxicam to see any tumor effects on ultrasound. Abby is very happy now and has a great quality of life. Purdue is now researching other drugs like Celebrex for possible treatment. Best information I found was at their website below. Good luck and hang in there. Abby is now walking 2 miles a day. Can't hold her down. She is a beagle mix with bad hips but the piroxicam also helps with that so she is happier than ever. The only thing we have seen since the stent is that she holds the squat a little longer. She isn't straining like she was when she was partially blocked but she doesn't seem to be sure when she's done. Our vet thinks it might be due to the stent going from the bladder and into the urethra so she is not getting the complete signal that the bladder is empty. She also sleeps through the night and has had no incontinence. Lisa www.vet.purdue.edu ›PCOP Home Abbysmom5809 Mon, 08 Apr 2013 00:00:00 GMT Also, I want to add that the vet said that with the piroxicam, she "may" live 2-3 months (if it works). Are there any holistic meds or foods I can add to her diet? I am completely heartbroken. Thank you and I am so sorry for everyone who lost their furbaby to this horrible disease. :-( LizziesMommy Mon, 08 Apr 2013 00:00:00 GMT My sweet baby girl Lizzie Bear, a 10 year old Soft Coated Wheaten Terrier, was diagnosed with TCC in her urethra last week. We had a traumatic catheterization on Sat, and it was confirmed. The started her on 5mg of Piroxicam on Sat. Any idea how long it should take to work? LizziesMommy Mon, 08 Apr 2013 00:00:00 GMT Kathy, I think you will know how it's going with Slice by really paying attention to how he responds to the regimen you are on now.  At this point, you don't have to worry about an ultrasound because it probably won't change anything, but usually as all have said 3 months is the norm.  I was given some good advice by a doctor who said that you need to look at the outcome and whether the procedure will tell you anything that will make a difference in how you treat. How well Slice eats will be a huge clue as to how he's feeling. With Bailey, she went from relatively good to pretty bad in one day.  Like Lynn, I was praying that she would go on her own so that I wouldn't have to make the decision.  Even now I sometimes doubt myself and say what if I had given her more time.  But then I go back to that day and Bailey couldn't really stand on her own and she would lay in her bed but not sleep.  She had eaten a good lunch but refused to eat anything for dinner.  Once I got her in the car and even at the hospital, as crazy as it sounds, she seemed at peace.  It seemed that the strength and willpower she always had to fight this battle was gone...the body was tired. As Lynn said about the renal values...those are the ones to pay attention to, especially where the creatinine is.  The cancer in time will eventually win, but kidney issues are immediately life threatening.  See what happens in the next few days and whether or not Slice responds.  There were a few times I thought Bailey was done for and she bounced back. Sending prayers your way, Karin Baileysmom97 Sun, 31 Mar 2013 00:00:00 GMT Kathy, The oncologist concensus for ultrasound is usually around every three months, but if the oncologist suggested euthanasia, skip it.  Why upset Slice unnecessarily going to the oncologist.  Renal panel (kidney values, at Slices regular is vet probably much cheaper) at your convenience to see how he is doing on the supplements.  If he starts vomiting, is lethargic, doesn't interact with you or his family, has completely stopped eating and cannot even be coaxed to eat,  check renal panel.  If BUN and creatine is on the moon (Chica's was; BUN 191, norm. 6-31 and creatinine 6.5,norm. 0.5-1.6), along with other high kidney values......you know what you have to do and I do NOT say that lightly.  My heart is breaking for you, for me, for all of us.  I'm hoping the supplements help.  This is where the "quality of life" chart is going to be a help...remember...you have to be brutally HONEST when you fill it out. This statement..."I  am not by any means ready to give up on Slice, but I dont that (think) he is going to get much better."...tells me at lot about what you feel (yourself) and see (Slice). I prayed and prayed and prayed that Chica would just fall asleep one night and not wake up in the morning...didn't happen.   Every morning there she was, looking at me with her beautiful topaz eyes, ready to start another day...so as long as the "quality of life" chart was doing good so were we...push onward. I will be thinking about you, your family...and especially Slice. ChicasMomForever, Lynn     ChicasMom Sat, 30 Mar 2013 00:00:00 GMT Hi again Kathy/Slomokat. I'm sorry, part of my cut and paste got cut out.  I meant low call kidney diet food -- Royal Canine makes S/O food for dogs needing a special diet low in calories and phosphates/salts.  I gave my Meg  both wet and dry S/O food.  Has Slice been recommended to follow such a diet.The paste sounds good for Slice -- keep him on it to  make sure he gets nutrients, but also try to ensure he eats some solid homecooked/steamed food, too, as you described.  The deciding factor for me deciding Meg could not live much longer was the 2nd ultrasound report she completed about 3 months after the initial one that identified likely tcc.  I don't know how often your vet recommends ultrasounds for Slice -- I somehow got the impression 3 months seems to be a standard period between ultrasounds.   Undergoing the 2nd ultrasound the vet said Meg was panting and moving and in alot of pain during the procedure (I could not be reached in time for them to get permission to sedate her for the procedure). The 2nd ultrasound revealed probable pyometra, thickening of the urinary bladder wall and the cancer mass seemed to stem from the proximal urethra (I think that's near the sphincters, can't remember).  Meg's kidneys' cortex also had hyperechoing/ seriously disease/was impaired.  I had to look that up that term -- see this site. http://www.veterinaryradiology.net/4161/what-do-hyperechoic- I wish I knew what advice you with Slice.  Everyone here will tell you a DIFFERENT story on how their dogs spent their final hours -- some peacefully, and others suffering terribly.  As for my other older dog, who just passed last Saturday naturally of heart failure at 14 years old -- his death was peaceful -- amazing.  We'd planned to take him to probably his last vet visit, but he beat us to it. He died in the garden in the shade. But it wasn't from tcc, but probably had a stroke episode or arrhythmia.  His meds had made him seriously nauseous, so I'd been handfeeding him for 2 days.  He struggled to move/was exercise intolerant. My groomer told me dogs will "withdraw" from the pack, and we should then begin to realize that death could be near. Again, their basic functions must be seriously impaired. Hope this helps a little.  Slice is lucky to have you and all of his pack, even if he can't show it as he used to!  Cathy      Cathtalk Sat, 30 Mar 2013 00:00:00 GMT Cathy, very informative Web MD link.  Thank you. Slice is not on any pain meds.  He recieve an ultrasound the night he has to spend away from his home, about 10 days ago.  The ultra sound showed one kidney blocked completely and the other at 30%.  He has not been back to the vet since.  I have been giving him SQs and my husband has him on some holistic "miracle cure" for kidneys (and if that works a supposed cure for his cancer.).  The supplements the husband has been feeding  Slice dont seem to bother him to much. The Superfood paste keeps somehting in his stomach when he doesnt want to eat. Question for Cathy - what is "low cal kidney" QUESTION for everyone- how often should I get an ultrasound/blood work?  The vet really didnt give Slice much hope the day I took him from the hospital.  (later I read the paper work from the oncologist,  which said euthnasia  would be the best course,and i had to sign off that I understood taking him home  that day was against the doctors recommendation).  DO i just go get his blood work done, or do I also need the ultrasound again? It would be good to know if the miracle cure has helped his kidney values And laslty, how did you know it was time for YOUR DOG to go?  Were they throwing up blood, or just have a sad look in their eye?  Sorry, but I gotta know.  Did you have to have them put down or is their such a thing a dying ( peacefully) in their sleep with this disease? I  am not by any means ready to give up on Slice, but I dont that he is going to get much better. THANK YOU EVERONE - this site is both unlifting and seriously informative. Slice and his brothers and sisiters, Dalton, Neumann, Frida, Evie and I thank you. Kathy Patrik slomokat Sat, 30 Mar 2013 00:00:00 GMT They were surprised. They thought they would have to really work hard to cath her. The tumor seems to move out of the way easily for now. After the first ultrasound and before. The cath she seemed to have relief, like the ultrasound had moved the blockage. Wish she could tell us. The stent is sitting exactly where the surgeon wanted it. She is sore from 4 days of being cathed, scoped, and having the stent placed. Trying to keep up with the tramadole and piroxicam for now. She is on sucralflate for her stomach. Thanks to everyone for posting about the slurry and timing. Abbysmom5809 Fri, 29 Mar 2013 00:00:00 GMT Kathy/Slices Mom, It goes back to my little made up ditty:   "I sleep, I eat, I poop, I pee, I am loved. . . . . . . Life is sweet!"    -Lynn   Cathy is right.  When Slice is at the vets/oncologists when they press in the lower abdominal area or kidney area, if he has been in pain, he'll show it. He might not yelp, but his reaction will tell it all.  Chica did get to that point, but I already knew she was going down hill because of the way she was acting and her "quality of life" scores were declining.  Here's the pfd so you can make a copy to use.  UNFORTUNATELY you have to be brutally honest when you fill it out. http://www.veterinarypracticenews.com/images/pdfs/Quality_of My sister-in-law (who has had many dogs, two of which had cancer) says it's in the look in their eyes.  I think she might be onto something. Cathy's "pets.webmd" article link is actually very good.  If one kidney is blocked and the other is 30%, it's something to consider reading.  Everything is worth reading, earlier is better than later, so we might be able to use some info.  Being informed is the best ammunition to fight this disease. Give Slice a nice belly rub for me...and a hug. ChicasMomForever, Lynn     ChicasMom Fri, 29 Mar 2013 00:00:00 GMT Slomokat/Slice's Mom, Please keep us updated on your Slice.  He looks and sounds very special and a lover of car rides from his pic.  Did ultrasound help you any further with understanding the extent of his kidney functioning?  Is he on pain meds too at this point?  Keep up with the water and also low-cal kidney I think Lynn is right when she says quality of life needs to be considered foremost.  They are so engrossed in day to day living with good food, sleep, as well as walks, car rides, the yard to play and hunt in, and attention from us (to varying degrees :)).  Basic day to day life and keeping tabs on us are essential, I guess.  My vet thinks dogs have a high tolerance to pain and won't show pain easily because they are such "pack" animals that can't show vulnerability.  Mabye when Slice gets examined or has procedures done, though, you may be able to find out the extent of much pain/discomfort he is in. Kim/my groomer said that dogs know when they want to pass on to the next world, and they'll try to let us know if we're receptive enough.  Please keep us posted!  Thinking of both of you in this difficult time!  Found this link for you, too, though it may be more than what you need right now. http://pets.webmd.com/dogs/kidney-failure-in-dogs    Cathtalk Fri, 29 Mar 2013 00:00:00 GMT On Mar 28, 2013 8:40 PM Abbysmom5809 wrote: Good news for Abby, she doesn't have a leak. It was a backup of the dye into the ureters. He rechecked her xrays and had a radiologist review them as well she is home now. YeahGreat news that your Abby is home.  Do you know if the stent was "easy" beacuse she was a female?   slomokat Fri, 29 Mar 2013 00:00:00 GMT Good news for Abby, she doesn't have a leak. It was a backup of the dye into the ureters. He rechecked her xrays and had a radiologist review them as well she is home now. Yeah Abbysmom5809 Thu, 28 Mar 2013 00:00:00 GMT Our little Abby was just diagnosed with TCC. Abby is 12 yr old beagle mix. We got her when she was around 4. We have another dog, Molly, who has had stones so I have to check her urine once a month. Her stones were from urinary tract infections. Abby has never had a problem. I luckily work in human laboratory, so my vet has me run the urines on Molly. It was time to check Molly again and I noticed Abby seemed to be straing as well. This was 7 weeks ago. I ran the urines and cultures on both. Both dogs had uti's from same bug. Both were started on antibiotics. I rechecked them and Molly was clear but Abby, who was still staining, had red cells and transitional cells. She had no visible blood, red cells only seen under microscope. Took her back to the vet and we switched her antibiotic for another 2 weeks. Did Xray for possible stones but did not see any. She was still straining and now was up every 2 hrs. (Up till 5 weeks ago, she slept through the night) again red cells and transitional cells but no visible blood. Tried higher dose of clav for another 2 weeks. No relief. Back to the vet. Another Xray, but still nothing we could put our fingers on. Our vet sent us to get an ultrasound. The ultrasound was done on 3/19 as well as a urine cytology. The ultrasound showed a smooth mass so diagnosis was not definitive. Saw our vet on Friday, she started Abby on piroxicam and misoprostol since it was most likely TCC. She had also done a rectal exam to try to feel the mass. For the first time in weeks, Abby slept through the night. We checked her at 3am to make sure she was OK. Sunday, we had partial blockage. Had to take Abby to emergency vet. He did another ultrasound. She was blocked at the neck of the bladder with the mass extending into the urethra. He cathed her which was luckily very easy. He thought it would have been much mure difficult, had a cystoscope done on Monday with biopsies taken at that time. Based on the cystoscope, we are sure it is TCC. The urine cytology from the previous week came back as negative. We had a stent placed on Tuesday. She has a pinhole leak in her bladder which the surgeon feals will heal itself. She is finally coming home today. We will give her the best quality of life we can for as long as we can make her comfortable. I never expected a healthy dog to suddenly be diagnosed with cancer and be blocked by it. Just going to cherish every day with her. Molly is lost since she has not been home. Thanks to all who have put their stories here. It really helped us on our decision to stent Abby and not put her down. Abby's Mom, Lisa Abbysmom5809 Thu, 28 Mar 2013 00:00:00 GMT Hi Kathy-- Talk to your vet about possible using Metacam.  It's a bit easier on the system but I don't know if it will be as effective. Bailey did well on Piroxicam until her kidney values went up. We then had to take her off that.  After some time she went on the Metacam (Meloxicam is another name) but the cancer did keep progressing, although slowly.  It's really a toss-up between the TCC and the kidney problems. At the end for us, Bailey's creatinine went off the charts and it started to come back down into a more normal range. We're not really sure what got her in the end, but it wasn't the TCC.  She had battled it for a little over two years, although it was very small when we first discovered it. From what my doctor said, I believe the kidney issues are much more urgent than the TCC, especially since Slice only has one functioning kidney.  Even with the Piroxicam, there is no guarantee...it works well for a lot of dogs but not necessarily for all. Good luck to you and Slice, Karin Baileysmom97 Thu, 28 Mar 2013 00:00:00 GMT Hi Kathy, Here's a link to explain piroxicam.  Hope this helps. http://www.oncolink.org/experts/article1.cfm?c=102&id=12 Piroxicam is the drug studied for TCC in dogs, however, I believe there are newer drugs that they also use now.  We went with the Purdue study and used Piroxicam with misoprostol backup. The Piroxicam is for pain and inflamation and when Chica was first put on it, it shrunk her tumor to less than half it's size and kept it "stable" for all these years. Only after she had a bladder stone (and treated with the crappy RX diet for bladder stones) did the tumor start to progress.  It decreased the size if the stone, and was passed with urine.  That was in the summer of 2012.  I believe, in my heart and mind, that if we did not treat the bladder stone with this diet, the TCC would have not progressed so rapidly. It's a hard call as to what YOU should do at this point.  Talk with Slice's oncologist. What kind of shape is he in, more importantly, what kind of life can you expect FOR him.  QUALITY of life, not quantity, is something you always want for him.  I cannot even suggest anything...your vet and oncologist have to guide you...talk to them as to how you want Slice's life to be.  Be it short or longer, quality (meaning HIS enjoyment of life) should always be the utmost goal. I know (from experience) how hard it is not to factor in OUR feelings and wants and come to a decision.  I'm sure Slice comes first for you or else you would not be here asking these questions and looking for ways to help him. My heart and prayers are with you.  ANYTHING that you decide is the right decision...as long as you do it with love in your heart...for Slice. ChicasMomForever, Lynn ChicasMom Thu, 28 Mar 2013 00:00:00 GMT On Mar 27, 2013 10:10 PM Cathtalk wrote: Hi Slomokat.  I was just following your posts on Slice -- sorry to hear of his diagnoses.  My Megan had TCC and I put her to sleep in December.   She'd been on piroxicam earlier on in her illness and we think had severe allergic reactions to it, with excessive licking and red rashes across her stomach.  The original vet prescribed it without any antacid -- not good as my dog started to vomit as well. My newer vet immediately put my dog on sucralfate/carafate -- 1/2 gram tablet two times a day as stomach prep in addition to pepcid.  Here is how the vet told me to administer the sucralfate for my dog, who was about 28 lbs, to do before each dose of an NSAID like piroxicam: At least 1 - 1/2 hrs before meal, crush the sucralfate and mix w/ about 1 ml of water until the mixture is milky/slurry (look that word up).  Adminster to your dog with a syringe.   Then follow up with 2 pepcid tables (30mg each) at least 1/2 hour after that.  Give the pepcid time to prep the stomach. Then feed your dog his other medications as usual. The carafate/sucralfate is a great prep in addition to the pepcid.  Dogs tolerate it well.  My Meg never again had any episodes of vomiting. :) Just be aware that if you try to give your dog his other meds too early after administering him sucralfate, the sucralfate may hinder the uptake of the other meds (if I rememer what the vet said). See what your vet says also! Hello Megans mom, sorry for your loss.  I appreciate your willingness to help other dog lovers going through some of the same things you have had to deal with. Is Piroxicam the  only way to go?  It seems to have so many side effects, and with Slices previous creatine levels, and one of his kidneys pretty much shut down is  it worth trying again? He has pepped up, and I hate to start over with the Piroxicam, even with the carafate and pepcid suggestions, unless the consensus is that it could help without all the kidney side effects. I guess I am not understanding what to try again? And what are meds targeting? He is finally eating thanks to some suggestions about mirtazapine,i almost lost him and after a month of  Piroixcan and Leucarin , and I keep wondering if this is the best way to go. So, do i deal with the kidney and forget the bladder cancer?? I hate for his other kidney which is at about 30% to also shut down. slomokat Thu, 28 Mar 2013 00:00:00 GMT Hi Slomokat.  I was just following your posts on Slice -- sorry to hear of his diagnoses.  My Megan had TCC and I put her to sleep in December.   She'd been on piroxicam earlier on in her illness and we think had severe allergic reactions to it, with excessive licking and red rashes across her stomach.  The original vet prescribed it without any antacid -- not good as my dog started to vomit as well. My newer vet immediately put my dog on sucralfate/carafate -- 1/2 gram tablet two times a day as stomach prep in addition to pepcid.  Here is how the vet told me to administer the sucralfate for my dog, who was about 28 lbs, to do before each dose of an NSAID like piroxicam: At least 1 - 1/2 hrs before meal, crush the sucralfate and mix w/ about 1 ml of water until the mixture is milky/slurry (look that word up).  Adminster to your dog with a syringe.   Then follow up with 2 pepcid tables (30mg each) at least 1/2 hour after that.  Give the pepcid time to prep the stomach. Then feed your dog his other medications as usual. The carafate/sucralfate is a great prep in addition to the pepcid.  Dogs tolerate it well.  My Meg never again had any episodes of vomiting. :) Just be aware that if you try to give your dog his other meds too early after administering him sucralfate, the sucralfate may hinder the uptake of the other meds (if I rememer what the vet said). See what your vet says also! Cathtalk Wed, 27 Mar 2013 00:00:00 GMT You mention the probiotic called Azodyl- can you tell me what this has done for your doggies kidney and bladder issues?  My Slice has  a similar story with not tolerating Piroxicam, not wanting to eat, having terrible kidney  ( creatine) levels, and peeing about every hour, especially after I stick him with the sub q needle.   Mirtazpine and steak in butter have helped,  but I want to do all i can for him. slomokat Wed, 27 Mar 2013 00:00:00 GMT You mention the probiotic called Azodyl- can you tell me what this has done for your doggies kidney and bladder issues?  My Slice has  a similar story with not tolerating Piroxicam, not wanting to eat, having terrible kidney  ( creatine) levels, and peeing about every hour, especially after I stick him with the sub q needle.   Mirtazpine and steak in butter have helped,  but I want to do all i can for him. slomokat Wed, 27 Mar 2013 00:00:00 GMT Siena had her 6 week ultrasound yesterday and we got the astounding news that her tumor shrank by about a third in the last six weeks! When I saw the tumor on the screen, I thought the doctor was looking at the wrong part of the bladder because I didn't see bulk that I normally do. But, it turns out the tumor is much smaller. I am delighted and grateful.   After Siena stopped taking the Neo, she went on Piroxicam and a product called Veterinary Immune Tabs made by Ramaekers Nutrition. I also boost that with 1 tsp of MUSH from Fungi Perfecti and 200 iu of Vitamin E. Not sure if its the NSAID or the supplements that have led to the improvement, but I'm not changing a thing!   I know every dog will respond differently to treatments, but I wanted to share this news in case others are looking for options that have shown good results. It's nice to get some good news, at last, as we batttle this disease. SienasMom Fri, 08 Mar 2013 00:00:00 GMT Thank you Nita and Jenn for your posts.  Bailey was indeed a wonderful dog and I still cannot believe she is gone.  I know all dogs are special to their owners, but Bailey was a character and had such personality that even her doctor in Philly became quite fond of her.  Her Terrier traits definitely came through and I think that is what makes it so difficult...she wanted to be with me no matter what.  She was not a happy camper if I had to leave her...she would bite at the door as it was closing.  She was this little firecracker of energy, although she could chill with the best of them, as long as I was right next to her on the couch and we had gotten a good walk that day. I was lucky enough to find some video I had taken of her.  I had to laugh because in the first scenes I am trying to get her to do her tricks--play dead, roll over & bang-bang (a different version of play dead) and she was not interested in obliging me.  However, as soon as I mentioned 'cookie' or 'snack' that head whipped around, although I did have to actually get the biscuits and then she couldn't do the tricks fast enough!  I just miss her so, so much.  It really means a lot to me that so many of you have posted such wonderful messages and that Bailey seems to have touched your hearts as well.  Karin Baileysmom97 Mon, 04 Mar 2013 00:00:00 GMT Karin, I was so sorry to read your news. I loved all the stories you shared about Bailey. She seemed to be such a wonderful dog. I hope that you are doing ok after the loss and that there is lots of comfort from the others in your life who loved Bailey too. You certainly have the prayers and support of everyone here. Warmest regards, Jenn SienasMom Sun, 03 Mar 2013 00:00:00 GMT On Feb 28, 2013 9:06 PM Baileysmom97 wrote: Just wanted to say thank you to all of you for your prayers, good wishes and comforting sentiments.  It has been a week and it feels like it was just yesterday.  I miss her terribly and keep thinking she will appear around a corner or in the yard somewhere.  I'm trying to think about her and that she's not suffering any longer but it's been difficult.  I am hoping that with time it will get better, but as some of you have posted, it does not seem to get any easier.  Treasure your best friends, love them and take nothing for granted.  I always expected Bailey to have more time and then she was gone so suddenly.Dear Karin, I'm so sorry to hear about Bailey.  I want you to know how much I have benifitted from your participation on this site--I feel like I know you and Bailey personally.  I'm afraid that I have been more of a viewer, frequently reading the site but infrequently participating.  It is always painful to read that someone has lost their special friend, but it hit me especially hard to hear about your loss. I am lucky to have my Rocky still alive and doing fairly well, but I know what you mean, its never enough time.  It is clear that your love for Bailey was tremendous, and you certainly did everything you could for her.  Please know that you will be in my thoughts and prayers as you grieve this loss.  You have shared Bailey's spirit with us through your posts, and we will not forget her.  Love, Nita P.S. I'm worried that I have naot acknowledged all others who have been online and lost a pet through this terrible disease.  I value all participants of this site, and feel so very sad when I hear of anyone's loss.  I have had a lot going on in my life so that I haven't been as involved in this site, so please forgive me if you have lost your precious dog and I have not responded. Nita Sat, 02 Mar 2013 00:00:00 GMT It will get some better once you get past all the firsts. First Christmas, first birthday, etc. etc.  You will never ever forget her or at times lose the pain of her being gone. I miss Sadie daily, but I can now at least talk of her without crying.  It has been six months and I even stopped by our Vet's to say hello last week and before that day I would not have been able to go back.  I do wish I had known when we found out Sadie had TCC that it could take her so very quickly. I would have done some things differently. But I know I did the best I could with what little knowledge I had of the situation and I know she knew she was loved. At the end all I wanted was her not to suffer anymore, because the dog we loved so very much was no longer there.  MinnieMo Sat, 02 Mar 2013 00:00:00 GMT Thank you Sallie and Cathy for your words of encouragement.  Thankfully I don't think she suffered for very long.  What is strange is she seemed much more peaceful once I had her in the car and then even at the hospital I was stroking her head and she seemed at ease.  I have to say the doctor was really wonderful and not that it was easy, but she was gone in the blink of an eye and it was very peaceful. I know many of our buddies have not survived very long but I still feel like I was cheated out of time with her.  I never expected her to go this fast from something other than the cancer.  I remember when we first got the diagnosis, it seemed like the end of the world...that there would not be a lot of time.  However, she kept fighting and kept on living way beyond what was thought.  I was really hoping that we could prove some faith in the Neoplasene.  I still have a bottle of the Neo if anyone is interested in trying it. Karin Baileysmom97 Fri, 01 Mar 2013 00:00:00 GMT Karin, I'm so, so sorry to hear of Bailey.  She seemed to love life and in all your posts she seemed to possess the means to survive no matter what, and with you caring for her.  I remember post after post where you mentioned this.  I know she was your darling, too.  Through so many of her illnesses , you've had so many comforting words, insights and very insightful suggestions to offer all of us here.  I can only hope as Sallie said that she did not suffer in her last hours for long (it sounds as a kidney/a renal infection).  It is horrible, this disease tcc, but you and others and our little ones here are have fought extraordinarily brave battles when the doctors said otherwise, as have our little ones.    What would Bailey be doing now?  I like to think of my Meg that way at times.  She'd be snuggling into me in bed, as it is cold tonight.  I'm also writing poetry about her. Take care of yourself, and don't doubt you did everything that you could possibly do for Bailley.  Keep posting here, please.  (My other scottie is still with us, still having fairly good qualilty of life at 14 years of age, even with his cor pulmone/heart disease, and I treat him with the milk thistle daily for his enlarged liver/gall bladder, as well as heart meds.)   Cathy Cathtalk Fri, 01 Mar 2013 00:00:00 GMT I'm so sorry Karin.  I only wish that the end was not always the same.  But you are correct when you say it happens fast because that is what happened with my sweet Shelby.  things just went downhill so fast.  I'm praying for you and your grief.  We all have to go through it sooner or later.  I'm glad that Bailey lasted as long as she did with such a terrible disease as this.  Just know that she gave you her love and she knew you loved her dearly.  Someday maybe we can look back on them without tears but it is very hard.  My thoughts are with you. Sallie Shelbysmom2 Fri, 01 Mar 2013 00:00:00 GMT Just wanted to say thank you to all of you for your prayers, good wishes and comforting sentiments.  It has been a week and it feels like it was just yesterday.  I miss her terribly and keep thinking she will appear around a corner or in the yard somewhere.  I'm trying to think about her and that she's not suffering any longer but it's been difficult.  I am hoping that with time it will get better, but as some of you have posted, it does not seem to get any easier.  Treasure your best friends, love them and take nothing for granted.  I always expected Bailey to have more time and then she was gone so suddenly. Baileysmom97 Thu, 28 Feb 2013 00:00:00 GMT Apologies for v brief post.....Yunnan Baiyo can be very effective for excessive bleeding    http://www.modernherbshop.com/Yunnan_Baiyao_Yunnan_Paiyao_Yu LogansDad Wed, 20 Feb 2013 00:00:00 GMT Karin, Hang in there and enjoy every moment you have together with Bailey. You'll be in my thoughts and prayers. Jenn SienasMom Wed, 20 Feb 2013 00:00:00 GMT Well… Its been a week since they performed the laser ablation and Reese’s doing great. Full squat with a steady and solid stream… Dr. Mitch Robbins and the staff at Veterinary Specialty Centers in Chicago were absolutely great… After the procedure we were told the tumor was far more invasive then the Ultrasound indicated. He speculated she may have had another month or two as it had progressed up into the urinary track and was very close to complete blockage… He Oncologists has suspended her chemo temporarily until the lab comes back from the cultures they retrieved during the procedure. This something most Oncologists don’t have the luxury of having due to the likelihood of seeding with traditional culture sample retrieval. All in all it was defiantly worth everything that went into arranging this procedure just to see her pee without strain and now only goes 2 or 3 times a day rather that 10 or 15 straining to finish. I know its only a temporary reprieve but welcome all the same…. Rwhiteohio Tue, 19 Feb 2013 00:00:00 GMT Karin So sorry!  I only wish that this terrible disease would stop afflicting our beautiful dogs.  You have made all the right decisions so far so just keep making them.  It is is time, you will know.  I'm thinking of you and sweet Bailey.  Wish there was more I could say.  But just know that so many others are dealing with the same thing.  It's not much comfort but maybe some comfort.  So, so sorry! Sallie Shelbysmom2 Tue, 19 Feb 2013 00:00:00 GMT Things were going pretty well for Bailey until last week and then progressively got worse.  I was taking her to the hospital in Philly because it seemed like the infection she had a few months ago, suddenly came back.  Well on the way, she had a seizure so I had to go to my local hospital and she's been there a few days.  Her kidney values were really bad and they thought she was going into failure and told me putting her down was a reasonable choice. Bailey's regular doctor said not so fast and today her creatinine has come down and is only a bit high.  They are actually letting her go home tonight and we'll see how she does.  It pays to get a second opinion, especially from the doctor who knows your dog!  By no means is she out of the woods, she hasn't been eating so that's a big concern.  It's just been another crazy roller coaster ride, but hopefully once she's home, the appetite will kick in. I really didn't want to take her to this hospital...a doctor there in September told me that Bailey wouldn't live much longer so my options were somewhat limited.  Now here it is 5 months later and she's still fighting!  It just goes to show you that finding the right doctor is everything. Karin Baileysmom97 Tue, 19 Feb 2013 00:00:00 GMT Hi Siena's Mom, My beagle, Emily went to Texas A & M for the laser procedure October 2012. We had Dr. Barton (oncology) and Dr. Katherine Scott (internal medicine/surgery), who performed the surgery. It did not go well for Emily because she bleed too much and they couldn't see. She is one of the dogs who ended up with a catheter and a small cut urethra from the procedue. She is all healed now, and I felt awful for her at the time. However, I would recommend them without hesitation as they were wonderful and did their absolute best for Emily. Dr. Scott worked closely with me to take her home even with the catheter in because she hates being at the vet. We left the next day and stayed in a local hotel and then went home to Dallas the following day. The estimate I had was $1200 to $1500 for the procedure. If the procedure would work for her, I would do it again, but she apparently is somewhat of a bleeder and her tumors are in the worst location right at the opening of the bladder and the urethra. I checked with my local vet in Frisco, TX who did spayed her and removed a fat tumor. He indicated that Emily also bleed quite a bit during those two procedures as well. So it is not an option for her. One thing, check on the hotels because some, I believe the all the Marriott brands, while saying they are "pet friendly," charge a $100 pet cleaning fee. I think I ended up staying at the different Hilton brands or Hyatt brand-the longer term little suites with kitchenettes. One charged a $35 fee...better than $100!! Hope it all goes well for you and Siena!!  Karen LittleKaren Wed, 13 Feb 2013 00:00:00 GMT Well were in Chicago and waiting on the call for her being done with the procedure... Waiting sucks... Rwhiteohio Tue, 12 Feb 2013 00:00:00 GMT Thanks Lynn, I hope your time away was relaxing and healing. It must be hard without Chica. My thoughts are with you and thanks for hanging out on the board to help the rest of us. My vet spoke with the Dr.s at A&M today! SienasMom Tue, 12 Feb 2013 00:00:00 GMT Hi Jenn, The only reaction to the procedure was to the chemo.  Low Neuts resulting in a reduction of the vinblastine. We also went on a two week chemo schedual instead of the every week as planned.  Worked out well for us, we got on the road and finished the chemo at NC State when we got home, following Dr. Wilson's chemo plan. As for the actual laser ablation...the only reaction we got from that was a wonderful stream (pee) and ALL of us were finally happy and satisfied (Chica happy for obvious reasons and we were happy just to see her happy again peeing with abandon). Dr. Heather Wilson (at A&M) was Chica's oncologist and Dr. Audrey Cook was the doctor that did the laser ablation.  Chica was her first "small dog" for the ablation and we all talked at length before the procedure, to see if Chica was a good candidate. Dr. Cook assured me that they would take the utmost care and if they ran into any problem, they would abort the procedure and pull out.  As it turned out, the procedure went as planned and we got a full year.  Dr. Wilson was in charge of choosing the chemo and starting it.  I cannot say enough about these two Dr.'s.  They are the best as far as we are concerned. I hope this helps. ChicasMomForever, Lynn PS  Sorry it took so long to reply, we are on the road (we just HAD to get away from the house, too many memories flooding in, good and bad...too sad...too EVERYTHING, at this point).   ChicasMom Tue, 12 Feb 2013 00:00:00 GMT Lynn, what was Chica's reaction to the procedure? Do they experience any side effects? Sounds like something I'd like to look into for Siena. Texas isn't that far from Utah. Can you share the name of the vet who did the procedure? Thanks. I love the information and hope this board provides. Jenn SienasMom Sat, 09 Feb 2013 00:00:00 GMT On Feb 08, 2013 4:27 PM Rwhiteohio wrote: We are traveling from Cleveland to Buffalo Grove, IL to the Veterinary Specialty Centers to see Dr. Mitch Robbins. They are one of only 3 clinics I’ve found that perform this procedure. The one in NJ another in TX. I am looking at $2500 to $3000.00 for the procedure. Its true it’s not a cure but the de-bulking does provide her relief and helps the Chemo do its job. Although limited the information and results are promising. I will update after her procedure on Tuesday next week. Hi, Go for it if possible.  Chica got a full year after her laser ablation (backed with Vinblastine chemo) at Texas A&M Veterinary Clinic.  We were not going for "quantity", we were trying for "quality" of life.  I guess we lucked out, we got BOTH.  She was her old "new normal" self almost immediately after the procedure.  Peeing normally and enjoying life again. Keep in mind that TCC will finally win in the end (don't kid yourself IT WILL win eventually), but like us, don't let it win easily. Every GOOD day is a gift, fight for it if you have the capability of doing so. My heart, mind and prayers are with you BOTH. Good Luck! ChicasMomForever, Lynn   ChicasMom Sat, 09 Feb 2013 00:00:00 GMT I only wish this were available in the UK (it apparently isnt). I contacted dr cerfs clinic a while ago. If appropriate please go for it! It may also allow extra time for non allopathic remedies to do their stuff and chemo as well. Good luck to you! LogansDad Fri, 08 Feb 2013 00:00:00 GMT Best of luck. I agree to try anything and everything you can afford. I did the same and it was worth every penny. Feel my hug. Iloverio Fri, 08 Feb 2013 00:00:00 GMT We are traveling from Cleveland to Buffalo Grove, IL to the Veterinary Specialty Centers to see Dr. Mitch Robbins. They are one of only 3 clinics I’ve found that perform this procedure. The one in NJ another in TX. I am looking at $2500 to $3000.00 for the procedure. Its true it’s not a cure but the de-bulking does provide her relief and helps the Chemo do its job. Although limited the information and results are promising. I will update after her procedure on Tuesday next week. Rwhiteohio Fri, 08 Feb 2013 00:00:00 GMT I explored it for my dog, and I was told it as not a cure but when used with chemo could extends his life by a few months.  Iloverio Fri, 08 Feb 2013 00:00:00 GMT This treatment is also very expensive, atleast in New Jersey.  I had gone to see Dr. Cerf, a great guy, but it would have been about $8,000 and it usually does not remove all the TCC. Baileysmom97 Thu, 07 Feb 2013 00:00:00 GMT We are dealing with TCC with our little girl Reese. She is 11. I found a treatment synonym UGELAB Ultra Sound Guided Endoscopic Laser Ablation. I have only found 3 vets so far that perform this procedure. One in New Jersey, Indiana and Texas. There may be more but they are hard to find. This procedure Debulks the tumor and works well in conjunction with Chemo. Rwhiteohio Thu, 07 Feb 2013 00:00:00 GMT I was researching Rose Laurel OPC for dogs & I happened to read someone saying great things about a product called PROTOCEL. I also have my best bud battling TCC. Has anyone used any of this stuff? tryeverything Wed, 06 Feb 2013 00:00:00 GMT There was something that was elevated but still within normal limits. I can't remember what it was. But the vet just watched it. I hope bailey does ok on a higher dose. I'm praying for her! Shelbysmom2 Tue, 05 Feb 2013 00:00:00 GMT It's only been two months since Bailey has been on the Neo.  From the last ultrasound, which was almost 4 months ago, there was still a mild progression of the TCC but overall it wasn't bad.   We are going to try increasing the dosage of the Neoplasene and see if Bailey will be able to tolerate it. Sallie, did Shelby ever have high BUN numbers while she was on the Neo?  Bailey's went up from 148 in December to now 160 but the creatinine was in a normal range.  However, the doctor is thinking it's kidney dysfunction. Baileysmom97 Tue, 05 Feb 2013 00:00:00 GMT So sorry to hear this, it is so very, very hard to let them go. I miss Sadie every day.  MinnieMo Wed, 30 Jan 2013 00:00:00 GMT Lynn I'm so sorry.  My heart is breaking for you and for all of us that have fought this disease and eventually said goodbye.  Your post made me cry.  All I can offer is what you already know....that you loved her completely, you did the best for her always, and you made the right decision at the right time.  Your grief will be hard to get through but you will get through it.  And I will tell you as I tell everyone that I think it is important to consider getting another dog when the time is right.  I say this because there are so many who don't have good homes and we all know we are good dog owners so it seems a shame not to lavish that love on another dog who is in need.  I truly believe that my other 3 have helped me get through my loss of Shelby.  Even though not one could replace her, it has helped just to have them at my feet when I cry for her.  I'm not trying to be pushy or anything so please don't take that wrong. My heart goes out to you and all who have lost.  Thanks for sharing your journey with all of us. Sallie Shelbysmom2 Wed, 30 Jan 2013 00:00:00 GMT Hi All, "It's always very hard to make the call...as to when...but we all have to make it sooner or later". This was a quote from "me", not too long ago.  "Later" has arrived. I just want to let all the wonderful people (that I have met on this site) know that Chica finally went to her rest on December 27, 2012.  I can honestly say that the last three days before she went, were the worst ones of the whole entire three years, five months and eleven days. I've always felt, with every day she stayed with us, was fairly pain free and was enjoying life, that we were actually thumbing our nose at TCC.  THIS is my only satisfaction.  I knew "it" would win, but darn it, "it" would not win easily (and didn't). I posted a remembrance of Chica on the main board.  All the angst that I have suffered with each and every pet that has gone before did not steel me for the actual loss and emptiness that I feel.  I cry for all of us. Keep fighting...every day is a gift...accept it graciously and enjoy it. ChicasMomForever, Lynn ChicasMom Tue, 29 Jan 2013 00:00:00 GMT Hi Sallie, thanks for the response on the squatting. With all of Bailey's issues the last few months, her symptoms have been changing constantly so I just never know what is causing them. According to Buck Mountain's website info, it appears that Neoplasene 75 is 75mg per cc and that Neo 300 is 300 mg per cc if I'm reading their info correctly.  Bailey is only 10 pounds but is on such a miniscule dose I wonder if it's having any effect, although she is on the Neo 300.  Her doctor at UPENN is very thorough and she calculated Bailey's dosage so am I hopeful that it will work.  At the moment her dose is .18ml once per day (1 cc=1 ml).  The first test will be in a couple of weeks when we go for an ultrasound. Karin Baileysmom97 Sun, 20 Jan 2013 00:00:00 GMT Hi All So sorry that Sienna is not getting better.  I so hoped she would.  to answer Baileysmom's question.  Shelby did the same thing with squatting for a long time.  I think it is due to the tumor because she was doing it before we started the Neo.  I might think about increasing Sienna's dose also.  Shelby was taking 1cc morning and night.  I don't know the milligram though.  I didn't realize there was more than one choice on that.  Wish so badly that I could do something to help you all out.  It's so sad and I hate this disease. Sallie Shelbysmom2 Sat, 19 Jan 2013 00:00:00 GMT Sorry to hear about Sienna's ultrasound...I had such hope that it would work.  Which Neoplasene is she on?  I believe one is Neo 75 and the other is Neo 300.  Bailey is on the 300 which is much stronger and thus you can give it in a smaller dose.  I would probably try increasing the dose, but you could probably call Buck Mountain and see what they recommend.  I believe I've spoken with Kay and she always seems willing to help.  I came across another dog, named Abby who is a Rotweiler and has survived about 4 years with hemangiosarcoma and has been taking Neoplasene.  The original prognosis was also only a few months. In any event, I would probably boost the Omega 3's and consider EGCG extract.  Bailey's tumor responded well for the first year on the EGCG and piroxicam. One question I had regarding Sienna was if her urinating habits changed at all while she's on the Neo?  Bailey seems to have to squat a fairly long time and I'm not sure if this is the cancer or the Neo.  Sallie, if you read this, did Shelby have any such symptoms? I'm not sure you're going to find anything that can get directly to the bladder unless you do the infusion...everything gets processed through the stomach. Baileysmom97 Mon, 14 Jan 2013 00:00:00 GMT Hi SienasMom Have just posted a lengthy reply, but not sure if it actually went through!  plse let me know if you don't receive Best Garry and Logan LogansDad Mon, 14 Jan 2013 00:00:00 GMT Sorry I forgot to mention that parasite control is vital, & I have been using 'diatamaceous earth' for about 2yrs now, so he's not having any poisonous chemicals. If you look up WOLF CREEK RANCH it'll give you the dosages, you can buy it from them as well. tryeverything Mon, 14 Jan 2013 00:00:00 GMT Hi Sienna's mum, I would to give you some names of supps that I have been using on my 12yr old Maltese X who has a bladder TCC, & given 2mths to live, that was 6mths ago. I put him on DHA omega 3 500mg 1xday, K9Immunity with K9Transfer, 2caps of Vascustatin, 1tab Vit E with Selenium & 2 caps of Salvestrol. I mix all this into his lunchtime meal of raw mincedmeat with steamed vegies (already mixed together in daily rations which I freeze & I boil chicken breasts & cut them up & mix in with the meat & I keep the broth & pour a little on each meal. For the night feed again use the meat & chook but this time I have a supp called AVEMAR which I sprinkle & mix into but using a bit more of the broth because this stuff needs a liquid pathway. In the morning he has 1cap of IP6 Inositol mixed in a little warm milk. Over the time I have tried other supps, but I have found this protocol works best for him & so far he's showing no affects from the tumor, no weight loss or lack of energy output. I am just going along without any support whatsoever because my vet chose to deny any alternate course of treatment, in fact I have not heard from them from the time I chose not to go with conventional treatments, so that tells me a lot, but if I can help someone I am more than happy to pass on my experience tryeverything Mon, 14 Jan 2013 00:00:00 GMT Hi Sienna's Mom. I had to put my wonderful scottie dog Megan to sleep the other week (after an ultrasound determined tcc had spread to the sphincters and likely was affecting her kidney functioning. She also was suffering from pyrometra).   Now our older scottie dog is battling liver cancer that may have metastasized to other organs.  I'm giving him Denosyl (which has some milk thistle in it) while we see vet specialists. In my searching today, I came across this database for tcc.  You may want to have a look: http://www.txchiro.edu/external/db-alpha.html Here is one suggestion, via my friend, but it was only for urinary tract infection, not cancer.  She induced her dog to drink some peppermint in water, and she claimed it helped clear the problem up.  I personally use enteric peppermint capsules for irritated bowel, and I noticed it does also work its way through my urinary tract and makes it feel tingly. Here's one thing on peppermint. http://www.umm.edu/altmed/articles/peppermint-000269.htm Ask your vet, though. There are some other herbs to be careful of.  I've just been reading about ones with aristolochic acid that may be linked to some cancers.  I hope you can find some new treatments. Cathy/Megan&Darnley's 2nd Mom   Cathtalk Sun, 13 Jan 2013 00:00:00 GMT I wish I had good news to report, but Siena's ultrasound this week showed that the tumor has grown and is nearing the area of the urethra. I'm so disappointed, but I know that this cancer is hard to beat.  I am looking for new ideas for treatment today. I can't say that the neo didn't work, because the tumor was held in check for a while (she's was diagnosed 10 months ago).  I've even thought about trying to increase the dose or do a bladder infusion. Has anyone tried that? Nonetheless, I'm reluctant to stick with it and expect a different outcome. I want to try something else that might be more effective. I looked again at the mix Shelby was on and bought some L-Glutamine powder and Curcumin to add to the omega 3's I already had her on. My vet is trained in chinese herbs and she is going to look into that as well. A friend of mine suggested trying to provide medicine in her water (or in liquid form) as that might find its way to the bladder faster than something that goes through the bloodstream. Has anyone heard of treatments along those lines?  I feel like I'm grasping for an answer right now. I know you can all understand the desire to find something that will help our canine family members battle this effectively. She's sitting at my feet right now, resting her head on my leg and looking at my with her sweet brown eyes. If anyone feels like sharing treatments that they have felt to be particularly effective, even if it just buys some time, I'd love to hear.  SienasMom Sat, 12 Jan 2013 00:00:00 GMT Garry Her tumor was in the trigone area. It was 1.70 cm. Shelby was also on several supplements like Duralactin and a probiotic. She also took Greek yogurt and Reglan everyday for nausea. She also took Piroxicam every other day. Other than that there was no conventional sort of treatment. Keep us posted on Logan and good luck to you. Shelbysmom2 Thu, 10 Jan 2013 00:00:00 GMT Hello Jenn I really hope that Sienna has good news this week. Logan had the third session of vinblastine today (following 8 sessions of mitoxantrone), plus u/sound and thoracic x-ray............ Our oncologist explained to me, that with TCC, any blood may be as a result of the tumour, growing, shrinking or even just remaining the same, due to the very vascular nature of the bladder. The option of blood plus any other material being expelled was never mentioned. However, apart from reading Shelby's story, I also recently read about a man whose bladder tumour disappeared under similar circumstances.  He had bladder cancer - urinated blood and what looked like clots - went to ER - following various diagnostics it was discovered the tumour had gone! I believe he was receiving another 'alternative' therapy, not neoplasene.  The above examples are probably not isolated incidents.  Whether they are more common, is not the point.  The point is, that although possibly extremely uncommon, it is at least possible for our canine family to be relieved of their respective bladder tumours - which does give us hope. Garry and Logan LogansDad Wed, 09 Jan 2013 00:00:00 GMT It's wonderful to hear that Shelby's tumour disappeared, Sallie.  Although some dogs can live relatively long lives with TCC, it's rare to find cases where the tumour actually goes. I would be very interested in knowing where Selby's tumour was, in her bladder, e.g. neck of the bladder, urethra, etc.  Was she receiving any other 'conventional' or complimentary treatment at the time? Our Logan is currently fairly new into a second chemo drug (vinblastine) and I am keen to explore all options for him, as I'm sure others are too. Many thanks Garry and Logan LogansDad Wed, 09 Jan 2013 00:00:00 GMT Just wanted to post an update on how it's going with Bailey.  She's been on the Neoplasene for about a month and all is going extremely well.  There have been no bad side effects and she has not had any trouble taking it.  She's on Neoplasene 300 so she can take a smaller dose.  Everyday she is improving...she just turned 15 but is still running around like she did a few years ago. We will probably have an ultrasound in another month to see if there has been any effect on the TCC.  I really think people should consider Neoplasene, especially if other options are not available.  I will keep everyone updated as we go. Baileysmom97 Tue, 08 Jan 2013 00:00:00 GMT Shelby peed in the kitchen one day and it looked like it had blood clots in it. I thought it must be worse but when we went to the vet that's when the tumor was gone. She said she probably expelled it that day. I think it's possible that Sienna's tumor is coming out a little at a time maybe. Watch for anything that looks like mucus or clots. I will jump for joy if you find out its gone! I can't wait to hear! All the best to you and her! Sallie Shelbysmom2 Mon, 07 Jan 2013 00:00:00 GMT Hi Sallie, I was wondering if you could tell me what happened when Shelby's tumor went away. Did she have symptoms or any blood in her urine? Now that is winter here in Utah, I can see blood in Siena's urine. I am going to get an ultrasound this week to see what is going on with the tumor. While it could be getting worse, I like to hope that it might be going away as well. Any info you have on what Shelby went through when she lost the tumor would be great. Thanks, jenn SienasMom Sun, 06 Jan 2013 00:00:00 GMT Well we went for the surgery consult and right now, surgery is off the table.  Bailey's BUN number was off the charts.  Normal is around 30 and she's always been high between 50 and 80.  This last time it was 148!!!  There's no urinary tract infection so we're trying to find out why...don't think it was the Neo since I had her off it for a few days in anticipation of the surgery.  Anyhow,  perhaps it was an isolated event because she has continued to improve.  She seems to be full of energy and we've been doing hour long walks every day.  And, she's been back on the Neo for over a week now.  I think I may see if the Neo has any effect on the thyroid tumor...the one good thing was that it didn't change much in size.  Hope everyone is having a great holiday. Baileysmom97 Wed, 26 Dec 2012 00:00:00 GMT I'm so glad she's doing well. I hope the Neo works. It sure did for Shelby. Keep us posted. Sallie Shelbysmom2 Tue, 11 Dec 2012 00:00:00 GMT I continue to be amazed by Bailey.  It's just about 2 years now that she has had this cancer and she'll be 15 next week.  We just finished a 45 minute walk and she was running down the trails! I started her on a small dose of Neoplasene on Saturday and so far so good.  We'll see whether or not this works.  I have decided to go ahead with surgery next week to remove a thyroid tumor.  The doctors feel because it's still small and not involved with the blood vessels that it's the best time to do it.  I'll post with more updates as we go. Karin Baileysmom97 Tue, 11 Dec 2012 00:00:00 GMT Thanks v. much to all of you.  Apart from one or two associates, my friends and co-workers really don't seem to be able to relate to my feelings about Megan's passing, as I guess they see her as an animal and not as a member of a family.  I've been crying when people can't see.  I wish I could have known and focused less on our other older dog earlier this year and focused on her.  It could have added more months onto her life.  I wish I knew for sure that it was the right time, though I read what Karin said.  I know she was beginning to suffer more and more, but how much I'll never know.It's night time when I miss her the most as that's when I'm home.  Our older scottie for the last day or two seems to be positioned to watch the kitchen door to see if she is coming back.  He also checks her food dish often, out of habit.  The cat as well seems to be more jumpy.  Must go.  Thanks again.   Cathtalk Wed, 05 Dec 2012 00:00:00 GMT So sorry to hear this, and yes all of us that have already been there, know how hard it is and how much you miss her. I miss Sadie every day and still cry over the littlest reminder. I got upset just getting out the Christmas decorations as she loved the lights.  My Vet gave the link to this article when Sadie died and it did help, http://www.helpguide.org/mental/grieving_pets.htm The greatest help to me was him telling me that she only knew she was loved and no longer in pain.  For me however the hard part was knowing she was gone.  MinnieMo Tue, 04 Dec 2012 00:00:00 GMT Dear Cathy, I'm so sorry to hear of Megan's passing.  As others have said, it never seems like the right time, but knowing that you put Megan's good above your desire to keep her will, I hope, give you some solace. Love and hugs to you.  I know that some day I will experience the pain you are in right now and I can only hope that some day a cure is found for this horrible disease.  Please take good care of yourself and know that others care.  Love,  Nita Nita Tue, 04 Dec 2012 00:00:00 GMT Hi Cathy, just terrible to hear of your loss.  I know it will never feel like it was the right time for them to go.  You made the best decision you could and take comfort in that...we never want them to suffer just to be here longer with us.  Karin Baileysmom97 Mon, 03 Dec 2012 00:00:00 GMT Cathy, so sorry for your loss. As Lynn said, we all have done everything we could to make our furry babies life as well as it could be.  Making that decision is the hardest thing but just know Megan is not it pain anymore.  Chloe has been gone 2 1/2 months and I still can't believe she is gone.  I do know she was suffering that last day and I had to do what was best for her. I also wish you peace of mind and comfort during the coming days.  Just know others are thinking of you and know what you are going through. Susan, Chloe's Mom Chloebeaglemom Mon, 03 Dec 2012 00:00:00 GMT Hi Cathy, I am so sorry for your loss of Megan. It is always very hard to make the call....as to when....but we all have to make it sooner or later.  With this disease it's even harder.  Some days they are fine (the new normal) and others, it seems, they are on their last leg. I think the best thing for us to remember is, that we gave it our all, and when we DO have to make that decision we know, in our hearts, that we did everything in our power to give our furry little children the best life that we could possibly provide under the circumstances. I wish you peace of mind and soul.  Megan is at peace now, chasing squirrels and lizards with all the other's that have gone on before her (they're having one heck of a time).  Close your eyes....see her....she is young again, happy and healthy!  Yes....I wish you peace. ChicasMom,  Lynn   ChicasMom Mon, 03 Dec 2012 00:00:00 GMT Hi everyone.This morning I had my wonderful scottie, my little one, Megan, put to sleep.  It felt too early for me, but hopefully for her it was the right time.  She was in pain, but still having good quality of life. She had a good weekend, with a visit to the dog park, special meals, lizard and squirrel hunts, and a good early morning walk.   My heart feels so empty now.   I know I'll be looking for her greeting and warm body on my sofa, as well as our car rides, for many months to come...Thank you to some of you on this forum for your support and advice throughout.  There were some really scary times.  I Cathy/Megan's 2nd Mom  Cathtalk Mon, 03 Dec 2012 00:00:00 GMT Good to hear Bailley's back on her feet!  Eating and walking in the park too! Keep us posted.  As for my little one, Megan, we had some bad news on Tuesday from a second ultrasound.  It seems that the bladder tumor seems more extensive than we'd thought from the initial ultrasound -- it may be stemming from the proximal urethra/in the urethra too -- in the bladder the mass is 2.8 x4.5 cms and multi-lobulated.  Worse still, my dog has inflamed uterine horns or maybe pyometra -- she needs surgery.  Her not being spayed is my fault, completely.  We'd hoped to breed her, and then did not).   I"m in the middle of making a very sad, difficult decision on her quality of life right now and I think we've come to the end of the battle with her cancer, now with this other issue. On the plus side at the moment: she's on tramadol for pain, as well eating ok, and for now, no hydronephrosis in the kidneys (I guess that is when the urethra gets blocked and fluid swells the kidneys?).  Take care of yourselves and the little ones!    Cathtalk Thu, 29 Nov 2012 00:00:00 GMT I thought it was over for Bailey...the weekend before Sandy hit, Bailey had stopped eating and drinking.  The 29th I was going to take her to the vet but they were cancelling all appointments and said only if I were to euthanize her, I could bring her in.  Well thank god, I didn't.  I gave her baby food and water with a syringe and she started eating and drinking again.  It turns out, she got really bad nausea and stomach churning from the antibiotic she was on.  We tried switching and now have also added an appetitie stimulant which is working wonders.  She has gained some weight and is back to walking in the park! She still may need surgery to remove a thyroid tumor but I am also hoping to get her on the Neoplasene and see if that stops the cancer.  She's not ready to give up and neither am I.  Throughout this whole thing, I have decided to let her pick the time when she goes.  She has battled through so much that I don't want to make that choice unless it's completely obvious. Baileysmom97 Wed, 28 Nov 2012 00:00:00 GMT On Nov 16, 2012 1:00 PM Hamletsmom wrote: Our University of Florida visit has given us good news! The "mass" that had been seen in the trigone area and initially suspected as a malignancy, miraculously dropped in the bladder and they will be surgically removing two large stones next Wednesday!! We will be celebrating Thanksgiving day without Hamlet, but he will be released from their care either Thursday or Friday. They are very optimistic about the outcome but we will know more after his surgical consult on Tuesday. The University of Florida College of Veterinary Medicine is a wonderful, state of the art facility and we feel blessed having access to its talented and caring staff. Thank you to this site!! I gleaned useful dietary information that I will be implementing. Hamlet isn't out of the woods, but I am so thankful for the hope we have that it is stones only!!That is GREAT news!  I am so happy to hear that.  Lets keep praying for stones and no TCC.  MyPeaches Sat, 17 Nov 2012 00:00:00 GMT I'm glad you got to share our hopeful, good news. We pray that all is well when they go in to remove the bladder stones--they will biopsy the liver because it is enlarged, but they are trying to rule out things while he's in surgery. There is the possibility he has Cushings (sp?) disease--which is treatable, I guess. I am thankful that I found this site and send my best wishes to you all! May we all have a peaceful and friend-filled holiday season. Hamletsmom Fri, 16 Nov 2012 00:00:00 GMT My best, positive thoughts are going out to you and your bull terrier. May she continue to thrive and keep the tumor shrinking. My best, Carolyn Hamletsmom Fri, 16 Nov 2012 00:00:00 GMT Hello I am new to the forum and came across the forum via google as my 9 year old girl (staffordshire bull terrier) was diagnosed with bladder cancer TCC at the beginning of the year. I'd noticed blood in her urine - we had snow in London and it was very obvious. Treatments for UTI/cystitis were given, (and didn't work), nothing showed up on urinalysis or blood tests, then an ultrasound revealed what the vet thought might be polyps, a biopsy was then performed through the urethra and it came back as TCC. Other than the blood in the urine she showed no symptoms of anything being wrong. I had always been opposed to giving dogs chemo as I'd seen my best human friend go through it all with NH lymphoma, but when it actually happens it's funny how you change your mind! I decided to give one doze of mitoxantrone and see what effect it had on her. When the VN gave her back to me she had more energy and life then when I dropped her off and was barking and wiggling. We did a course of four doses of mito spaced 3-4 weeks apart and she is on daily peroxicam. Back in July the ultrasounds show the tumours had shrunk from 2-3 cm to 1cm so we made good progress and decided to see how it went and rescan in January. She does a lot of little wees, and can take a long, long time to finally poop, but she eats well, goes on long walks, I took her off peroxicam 2 weeks ago and it was a big mistake as she has started peeing overnight, it's like she can't hold it anymore. She us also drinking tonnes of water! I gave her a peroxicam this morning went out to work and came home to no accidents, would it have worked that fast? Sorry I have whittered on, we have a Vet appt Monday so will update after. MissP Fri, 16 Nov 2012 00:00:00 GMT It is wonderful to get such great news before Thanksgiving!  We lost our 11-year-old Wheaten, Rio, to TCC on Memorial Day.  I almost dropped off this site yesterday, but now the good news I was hoping for came through!  Kidney stones are a good thing compared to TCC.  Goood for you and Hamlet! Iloverio Fri, 16 Nov 2012 00:00:00 GMT Our University of Florida visit has given us good news! The "mass" that had been seen in the trigone area and initially suspected as a malignancy, miraculously dropped in the bladder and they will be surgically removing two large stones next Wednesday!! We will be celebrating Thanksgiving day without Hamlet, but he will be released from their care either Thursday or Friday. They are very optimistic about the outcome but we will know more after his surgical consult on Tuesday. The University of Florida College of Veterinary Medicine is a wonderful, state of the art facility and we feel blessed having access to its talented and caring staff. Thank you to this site!! I gleaned useful dietary information that I will be implementing. Hamlet isn't out of the woods, but I am so thankful for the hope we have that it is stones only!! Hamletsmom Fri, 16 Nov 2012 00:00:00 GMT On Nov 15, 2012 8:03 PM MyPeaches wrote: On Nov 14, 2012 9:27 PM Hamletsmom wrote: Debbie, I've been scouring this site for the last week, since Hamlet's initial ultrasound and a possible TCC diagnosis. My vet suggested that we go to the university of Florida fora second opinion. Today they told me to plan on spending the day there and they mentioned a biopsy. I know you have just recently lost Peaches, so you may not be on this site often, but if you are: should there be any test I should steer clear of? I don't want to put hamlet through any unnecessary or painful testing, I know I'm getting too stressed in advance. . .but he is, like we spall say, the most precious, sweetest little friend. . . Thank you. CarolynFrom what the oncologist told me, the only way to determine 100% for sure if it is TCC is to get a sample of the mass.  In Peaches case, they inserted a urinary catheter and took out a fluid and cell sample of the mass.  I think that was called a cystoscopy.  Prior to that she had 2 ultra sounds and x rays which showed there was  a mass, but there was nothing definitive saying it was TCC.  I hated to put her thru that, but it was the only way to get the proper diagnosis.  I am so sorry you have to go thru this and I will keep you in my prayers Carolyn.  I will pray for a good diagnosis and NO TCC!!!!There is one other way to determine TCC...it is by obtaining a urine sample, spinning it and putting any remaining cells under the microscope.  This is how Bailey's TCC was determined.  She orginally was to undergo a cystoscopy but then they were able to find the TCC cells in her urine.  Definitely try that option before going the other route. Baileysmom97 Thu, 15 Nov 2012 00:00:00 GMT On Nov 14, 2012 9:27 PM Hamletsmom wrote: Debbie, I've been scouring this site for the last week, since Hamlet's initial ultrasound and a possible TCC diagnosis. My vet suggested that we go to the university of Florida fora second opinion. Today they told me to plan on spending the day there and they mentioned a biopsy. I know you have just recently lost Peaches, so you may not be on this site often, but if you are: should there be any test I should steer clear of? I don't want to put hamlet through any unnecessary or painful testing, I know I'm getting too stressed in advance. . .but he is, like we spall say, the most precious, sweetest little friend. . . Thank you. CarolynFrom what the oncologist told me, the only way to determine 100% for sure if it is TCC is to get a sample of the mass.  In Peaches case, they inserted a urinary catheter and took out a fluid and cell sample of the mass.  I think that was called a cystoscopy.  Prior to that she had 2 ultra sounds and x rays which showed there was  a mass, but there was nothing definitive saying it was TCC.  I hated to put her thru that, but it was the only way to get the proper diagnosis.  I am so sorry you have to go thru this and I will keep you in my prayers Carolyn.  I will pray for a good diagnosis and NO TCC!!!! MyPeaches Thu, 15 Nov 2012 00:00:00 GMT Debbie, I've been scouring this site for the last week, since Hamlet's initial ultrasound and a possible TCC diagnosis. My vet suggested that we go to the university of Florida fora second opinion. Today they told me to plan on spending the day there and they mentioned a biopsy. I know you have just recently lost Peaches, so you may not be on this site often, but if you are: should there be any test I should steer clear of? I don't want to put hamlet through any unnecessary or painful testing, I know I'm getting too stressed in advance. . .but he is, like we spall say, the most precious, sweetest little friend. . . Thank you. Carolyn Hamletsmom Wed, 14 Nov 2012 00:00:00 GMT Hi Peaches' Mom/Debbie. Sorry to hear of your dog Peaches. She looked like a very happy creature from her picture.  That she managed to live as long as she did with you -- 2 1/2 years instead of 6-12 months, is wonderful.   I'm sure you would not trade a minute for the love and happiness you shared. I hope her quality of life was fine for as long as it could be.  We'll be keeping you both in our thoughts/prayers. She's home now, with God. Cathy/Megan's 2nd Mom Cathtalk Tue, 13 Nov 2012 00:00:00 GMT On Nov 13, 2012 10:46 AM LogansDad wrote: Hello Peaches Mom I'm really so sorry to hear about your girl.  She clearly had so much love and care from you to be with you an extra 2 and a half years from the  TCC diagnosis.   Yes, it does offer encouragement and hope.... I apologise in advance for asking the following questions, as you're still grieving so much.  However, can I please ask if you were aware of the extent of the TCC, through ultrasounds, etc? And what treatment did Peaches have, including any supplements? Did she have any other health conditions? How old was Peaches? Peaches will certainly be running free in spirit and will be there for you in times of need.  She will also be waiting for you when it's your time to move on....hopefully, not for a long time yet...... Bless you and take care. Garry and Logan (DX May 2012, with TCC) Hi Garry, When Peaches was first diagnosed over 2 years ago, her tumor was less than 1 cm.  She has had multiple ultrasounds throughout this disease and the final was this past July when the tumor was taking up almost all of her bladder.  I did not put her thru chemo becasue she was deathly afraid to go into a vets office.  She did see the best oncologist in this area (PVSEC) in Pittsburgh when needed, but I had a vet come to my house to take urine samples and blood samples.  She was on piroxicam the whole time and Pepcid ac the whole time.  Occasionally she needed Tramadol for pain (alot in her last few months) and was on a multitude of antibiotics depending on what bacteria was growing in her culture.  I found a VERY good supplement called CranFlora which is a probiotic/cranberry capsule that I believe helped a GREAT deal.  I would recommend Cran Flora to EVERYONE on this site.  It helps with urinary problems.  She had no other health conditions and she was between 8 and 9 years old when she passed (she was a rescue, so we don't know her exact age). Debbie MyPeaches Tue, 13 Nov 2012 00:00:00 GMT Hello Peaches Mom I'm really so sorry to hear about your girl.  She clearly had so much love and care from you to be with you an extra 2 and a half years from the  TCC diagnosis.   Yes, it does offer encouragement and hope.... I apologise in advance for asking the following questions, as you're still grieving so much.  However, can I please ask if you were aware of the extent of the TCC, through ultrasounds, etc? And what treatment did Peaches have, including any supplements? Did she have any other health conditions? How old was Peaches? Peaches will certainly be running free in spirit and will be there for you in times of need.  She will also be waiting for you when it's your time to move on....hopefully, not for a long time yet...... Bless you and take care. Garry and Logan (DX May 2012, with TCC) LogansDad Tue, 13 Nov 2012 00:00:00 GMT On Nov 12, 2012 6:38 PM MyPeaches wrote: Hi everyone, this is Peaches mom. I just wanted to give everyone some encouragement. Two and a half years ago, my baby was diagnosed with this horrible disease and only given 6-12 months. She just passed away 3 weeks ago today. My heart is completely broken, and I miss her terribly. But, I was given so much more time with her than any doctor ever expected, and for that I am so very grateful. The love her and I had for each other was unexplainable. After going thru all this pain, a friend said something to me that really helped. She said " Peaches is now helping Jesus welcome souls into Heaven. She was too good and gentle for any other job." I can picture her doing just that! I will never find another dog like her, but I know I will see her again! I love you Peaches, and I miss you so much!!!So sorry to hear about Peaches passing. I know how hard it is for you. Chloe has been gone since Sept. 19th. Time does help but I still have days I just want to cry. It is terrible that our precious dogs had this horrible disease. We have all done the best we could to save them but TCC will always win in the end. You were blessed to have had Peaches as long as you did. Chloe was diagnosed on Jan. 2nd and made it about 9 mo. I hope you find peace in knowing you did all you could. The love of a pet is so wonderful. Chloe brought so much joy and love into my life. I will be thinking of you and hoping your days will get easier. Susan, Chloe's mom Chloebeaglemom Tue, 13 Nov 2012 00:00:00 GMT Hi everyone, this is Peaches mom. I just wanted to give everyone some encouragement. Two and a half years ago, my baby was diagnosed with this horrible disease and only given 6-12 months. She just passed away 3 weeks ago today. My heart is completely broken, and I miss her terribly. But, I was given so much more time with her than any doctor ever expected, and for that I am so very grateful. The love her and I had for each other was unexplainable. After going thru all this pain, a friend said something to me that really helped. She said " Peaches is now helping Jesus welcome souls into Heaven. She was too good and gentle for any other job." I can picture her doing just that! I will never find another dog like her, but I know I will see her again! I love you Peaches, and I miss you so much!!! MyPeaches Mon, 12 Nov 2012 00:00:00 GMT Hi Jenn. Glad to hear about Siena! Thanks for the message.  One oncologist had mentioned doing a needle aspirated of 1-2 of my dog's cysts on her belly/near her mammary glands/teats, as they've been swollen.  The swelling is mostly gone, thank goodness.  The regular oncologist yesterday did not think the aspirate was worth doing, and surgery at this point is not to be considered either.  We'll watch them, but we're more concerned about the TCC.  That bladder mass we don't want to aspirate or biopsy becasue it will likely spread to the wall of the bladder, as you said. Today I started my dog on Deramaxx and gave her some pepsid with it.  The oncologist had said we did not need to give her sucralfate/carafate, as deramaxx apparently does not have as many gastro-intestinal side-effects that piroxicam is known to have.  However, the more I've been reading about deramaxx this morning, the more concerned I am that there's still potential for gastro-intestinal upset/ulcers.  So, I'm going to start my dog on the sucralfate again later today.  I'll call my regular vet on Monday, and talk it over with her.  Neither of us (my dog or me ) want more stomach upsets than necessary. I found some good website resources-- I know many of you have yours, but  I thought I'd share mine, too.   Here they are Drugs.com site:Drugs.com /pro/deramaxx.html" target="_blank" rel="nofollow">http://www.Drugs.com /pro/deramaxx.html Mar Vist Vet Center has a fantastic pharmacy library --http://www.marvistavet.com/index.html I found this entry for sucralfate/carrafate.  It looks like it doesn't work well with some antibiotics and it may cause some constipation as a side effect:http://www.marvistavet.com/html/body_sucralfate.html Hope everyone's doing well. Cathy/Megan's 2nd mom   Cathtalk Sat, 27 Oct 2012 00:00:00 GMT Cathtalk, Are they going to do a needle aspirated of the bladder cancer or another mass? It's a really bad idea to do it of the TCC because it can spread the cancer to the wall of the body. The best way to sample the tcc is with a scope. You probably already know that, but i wanted to mention it, just in case. Baileys mom, I'm so sorry to hear what you both are going through. I hope Bailey gets stronger soon. Neo does work on lots of cancer types. I hope you are able to get her on it soon, even at a low dose. Siena continues to do very well on the Neo and I wish the same for Bailey! Best wishes Jenn SienasMom Fri, 26 Oct 2012 00:00:00 GMT Dear SP's mom, How does Sweat Pea seem to feel?  She looks so sweet, like her name. I hope you can figure out what's going on.  Have you called your vet to let him/her know of what you are seeing?  It sounds as if your dog's digestive tract/stomach/intestines might be very irritated if you're seeing blood in her stools.  Maybe you can get meds for that -- my dog takes sucralfate when she's on an NSAID for peptic ulcers. Take care and God bless you both.     Cathtalk Fri, 26 Oct 2012 00:00:00 GMT Hi all, I hope Bailey is doing better. Sweet pea had another round of chemo Tuesday and had a LOT of bright red urine today. She hasn't had blood in her urine in some time. She also had some in her feces. Has anyone experienced this after chemo or are we in for a progression of the disease? :( SP's mom SweetPeasMommy Fri, 26 Oct 2012 00:00:00 GMT  Hi Garry. Thanks for this information on hydroxyzine.  I will do more research. My dog finished one 14 day round of the hydroxyzine, but she finished the round about 3 days ago.  A far as I'm concerned, the fewer drugs she is taking, the better.  I'm very concerned about side effects and drug interactions. I feel that way for myself, too.  She is currently taking tramadol, and nothing else.   The oncologist did NOT seem to think the stomach rash my dog had about two weeks ago was related to her TCC possibly spreading.   The rash started to subside within a day or so of seeing the oncologist -- she had been on the hydroxyzine a few days at that point and we also had started the tramadol then. It is possible, though, the rash is linked to mammary cysts she suffers from. We're heading back to the oncologist tomorrow, as my dog may need a needle aspirate procedure to test the one or two cysts to see if they are malignant or metastisizing.  If that is the case, I will seek surgery for my poor dog for those right away as those will spread to her lungs and elsewhere. She shouldn't be too uncomfortable for the aspirate procedure as she's still on the tramadol.  Otherwise, she seems to be doing OK.  Just some straining when she urinates, a bit more than usual, but that is all I'm noticing.  We need to get her back on an NSAID as soon as possible. My overwhelming concern is to keep my dog as tumor free as possible where I can, comfortable, eating and exercising well, and not suffering in pain... We'll keep you posted.   Thanks again. Cathtalk Fri, 26 Oct 2012 00:00:00 GMT Dear Cathtalk Really sorry to hear about your dog (sorry if I missed her name).  If she has TCC she should NOT be on hydroxyzine.  Hydroxyzine should not be given to any dog with bladder cancer or where there is any chance of a urinary blockage.  Please google this for further info. All the best Garry LogansDad Thu, 25 Oct 2012 00:00:00 GMT Praying for you and Bailey...she certainly is a stoic character..and you, the most caring of Moms...many blessings being sent your way.. Chris cgallo02 Tue, 23 Oct 2012 00:00:00 GMT The mass seemed to be floating in the abdominal area and was not attached to anything.  What we assumed was pancreatits was not and just mimicked some of the symptoms.  It appears to have been caused by this mass which they think was infectious at some point, thus causing the fever and the pains, etc.  Her lungs and all else are good.  I don't believe the cancer has spread...she's just been doing too well and that area is not usually where the cancer goes.  It usually goes to the lymph nodes, lungs and then bones.  We should be able to tell in a few days if her neck does not get better on the meds, then most likely the cancer has spread.  Last night after I picked her up from the hospital, she was already zipping around the house like nothing happened! Bailey is a Rat Terrier, almost as crazy as a Jack Russell but thank god she is much more calm, but perhaps her spunk is what's gotten her through all this! I want to send my sincere appreciation to all who have wished us well.  We will continue to fight this cancer and see if we can blaze a new trail with the Neoplasene.  My goal is still to get her back on it once she's put on some weight. Baileysmom97 Fri, 19 Oct 2012 00:00:00 GMT Hi Karin/Baileysmom.Really glad to hear the surgery went well for Bailey (was it to do with her pancreas or bladder?).  I'm sorry to hear about the other development(s).  (The oncologist I saw the other day told me that longer surviving dogs with TCC often face cancer that spreads to the lungs.  Maybe this is too generalized, though.)  Are Bailey's lungs in the clear? It sounds as if she's gone through so much.  I was wondering if she's a boston terrier?  It's a bit hard for me to tell from her pic. Thinking of your both and hoping you'll both find the strength and help you need! Cathy/Megan's 2nd Mom   Cathtalk Fri, 19 Oct 2012 00:00:00 GMT Wish Bailey and you strength. Thinking about you, you're not alone. Kind regards Gabriella gabriella68 Wed, 17 Oct 2012 00:00:00 GMT Surgery went well and Bailey was already walking around.  We had to do a CT scan on her neck because they noted something which didn't look right on the radiographs.  Most likely appears to be an infection of the discs but a slight possibility that it could be the cancer spreading.  On top of that they found a small mass on her thyroid which they think most likely is a carcinoma!  Doctors say it should be removed but it would have been too much to do today.  I am at my wit's end with all of this.  Will research whether the Neo would work on the carcinoma.  Just can't fathom putting her through another surgery any time soon! Baileysmom97 Wed, 17 Oct 2012 00:00:00 GMT Praying for you! Keep us posted. Shelbysmom2 Wed, 17 Oct 2012 00:00:00 GMT Hi- Sorry to hear about the mass.  Please keep us posted and let us know how you and Bailey are doing. Nita Tue, 16 Oct 2012 00:00:00 GMT Well, her current problem may not be pancreatitis at all.  They discovered a 2cm mass in front of the bladder.  Awaiting a biopsy of that today.  She was severely dehydrated and had some neck pain that had returned, but all in all is doing much better today.  Now just waiting to see what this new thing is all about. Baileysmom97 Tue, 16 Oct 2012 00:00:00 GMT Well once again the pancreatitis has taken a turn for the worse.  Bailey is now at UPENN vet hospital for 24 hr IV fluids and the works.  This is just a killer of an illness.  Bailey has gone from 11.7 pounds in August to now 9.2 pounds.  This week alone she went from 10.7 to 9.2!  She can't even afford to lose what she has.  She was doing ok with being treated with sub q fluids on a daily basis with my regular vet but the pain seemed to get worse yesterday.  Just have to get this inflammation cleared up so she can start eating again.  Baileysmom97 Mon, 15 Oct 2012 00:00:00 GMT I hope it helps. I had a Scottish Terrier once, loved him greatly. TCC is a horrible disease and the best any of us can or did, was try to keep them comfortable without pain as long as possible.  Be sure to ask about giving her Pepcid with any NSAID, too. Sadie was given both tramadol and gabapentin by our oncologist and a half dose of Previcoxx daily.  Also when her belling was inflamed, I would put cool wash cloths on it, she seemed to like that.  The good thing about Vetercyn is it will not hurt her if she licks it and it helps restore the skin to its natural PH. Plus it seemed to make her skin cooler and less inflamed. We got it at the local pet store.  MinnieMo Fri, 12 Oct 2012 00:00:00 GMT Thanks very much responding! Yes, my dog's belly is still red/inflamed this time, and I think she is suffering, and I worry that she's in pain.  The rash wasn't there when we saw the oncologist last Friday, as it started 3 days after our visit (Sunday night) and also just about one week after we'd resumed the piroxicam.  I'd first thought it was just the medicine, but now it has been some days since we discontinued the piroxicam, and it hasn't gone away. No, Megan's not on tramadol.  I'll call and ask the oncologist about it tomorrow. The primary vet started her on something esle, hydroxyzine, but from what I read, it seems as if it is more for allergic reaction.  I'm familiar with Gabapentin in human form -- my older sister used to take it as the drug neurontin.  Thanks for the recommendation for the vetericyn again -- I'll go see if I can get some for her.  I've been trying tea tree oil, as well as bactine, but not with much success. Thanks again.  Cathtalk Fri, 12 Oct 2012 00:00:00 GMT We had our dog Previcoxx instead of the Piroxicam as that is what our Oncologist recommended. They are all NASIDs but if you have not tried it, it might be worth a try.  I will tell you that our Oncologist said dogs with TCC lick the area because of the pain. Is Megan on Tramadol. Also the oncologist put Sadie on Gabapentin for nerve pain.  Sadie's belly stayed very red and inflamed looking but the Oncologist said it was due to the cancer. I did get some Vetericyn gel spray and chilled it and sprayed Sadie's belly with it and it seemed to make her more comfortable and take away some of the redness, swelling and heat. www.vetericyn.com Prayers for both you and Megan. P MinnieMo Thu, 11 Oct 2012 00:00:00 GMT Megan was back on the piroxicam for a couple of days, when all the same allergic seemed to start up on Sunday night-- the excessive itching, scratching, and her stomach breaking out in a rash.  This has been happening even though she takes suralfate and pepsid before meals to help with gastro intestinal upset. So, we've stopped the meds for a few days.  Today The stand-in vet said to give her 25mgs of benadryl up to 6x a day (those little pink tablets).  They don't seem to be helping much, though. I'm also concerned about keeping my dog off NSAIDs for too long, though, because it's needed to help to slow the tumor growth in the bladder. The stand-in vet wants to put Megan on another NSAID, rimadyl.  Apparently deramaxx is in short supply, as a major factor that manufactures it, Norvatis (?) was closed earlier this year.  I'd prefer my dog first try the deramaxx, though, as it seems as though it might have fewer side effects.  Or, perhaps there is previcox.  Does anyone's dog here have any experience with those medications. I mentioned the misoprostyl to the stand-in vet, but she was skeptical about using it. As an aside..:( Tonight hasn't been a good night.  While walking Megan and the older scottie, Darnley, we had a run in with the neighbor's son's unruly Rottweiller, who was skateboarding and walking the dog at the same time. Megan growled at him, and in response the Rottweiller managed to drag the son off of his skateboard and over to my dogs, where he began to pick a fight with Megan and then my older scottie.  Fortunately, very luckily neither of my dogs were bitten and neither was I. But it wasn't easy breaking up the dog scuffles, and I got a scare.  I'm about to put the inflatable tube on Megan's neck tonight, in the hopes it might help her from her constant licking of her stomach.  I can only hope that we find some NSAID medication that will agree with her stomach.... If any of you here know anything more of rimadyl, please post.  It seems to me it might have more side effects than the piroxicam. Thanks very much!  Cathtalk Wed, 10 Oct 2012 00:00:00 GMT Sorry to hear it. Hope she's feeling somewhat better soon! Cathtalk Wed, 10 Oct 2012 00:00:00 GMT Bailey started the Neoplasene last week and all was going well until she had a relapse of her pancreatitis.  I don't think it was because of the Neo but am looking into that aspect.  I think it probably was the hibachi chicken she shared with me and maybe that overloaded her system.  This episode wasn't nearly as bad as the previous one but I will keep her off the Neo for the timebeing and let her fully recover.  I'll keep you posted as to how she's doing. Baileysmom97 Mon, 08 Oct 2012 00:00:00 GMT I'm so excited to see how Bailey does on the Neoplasene.  I wish you all the success we had with our sweet Shelby.  I just know that if she had been younger, she would still be with us and probably be tumor free!  Up until her death in June her tumor which disappeared in January still had not come back.  It would be wonderful if Bailey had a similar repsonse.  I'm pulling for her!!! Please keep us posted! Shelbysmom2 Tue, 02 Oct 2012 00:00:00 GMT Hi Chica's Mom/Lynn. First off, that Chica's still with you and has a good quality of life 3 years on is wonderful and not ready to go yet really encourages me, as the first vet who diagnosed my scottie dog, Meg, gave her at most a few months and no more than a year or two.  Does Chica strain when she urinates or take some time?  Does she have discolored urine even while on piroxicam?  Meg's is clear right now, but that is because she's just been on a higher dosage of antibiotic. I checked the name of the ulcer preventive my 2nd vet prescribed for my scottie Meg, and yes, I was wrong, it is SUCRALFATE she prescribed (1/2 gm tablet 2x per day, crushed, mixed with a bit of water), not succinate. Thanks for letting me know about  misoprostol.  I saw it mentioned a couple of postings back.  I'm going to ask the specialist about it and the sucralfate and these side effects you mentioned -- that misprostol and sucralfate are hard on the kidneys. Cheers!Cathy/Megan's 2nd mother          Cathtalk Sun, 30 Sep 2012 00:00:00 GMT Hi Lynn, Just over 4mths ago my maltese x was diagnosed with TCC & 3mths tops, chemo or drugs were not an option for us so I read everything I could  tried everything from Vascustatin, beta glucan, medicinal mushrooms  a raw meat diet with vegetables. So far absolutely no symptons at all, so I have put him on Salvestrol Platininum along with Germamium once a day.  He is doing so well, no weight loss nor loss of energy. Even though this is working I certainly will not be dropping my guard. Andys' mum. Deb  tryeverything Sun, 30 Sep 2012 00:00:00 GMT Hi, Chica has been on piroxicam for over 3 years with no problem.  The one thing that vets (and sometimes oncologists) tend to forget is something that works with the proxicam to protect the stomach.  MISOPROSTOL! When Chica was first DXed I researched piroxicam and lo and behold misoprostol came up.  Not from any vet or oncologist (they tend to wait until a problem arises before dispensing it).  Once the stomach starts to bleed or an ulcer arises is absolutely too late for me.  The article was written by veterinary tech and made sense.  I insisted on misoprostol w/piroxicam and here we are 3+ years later with no stomach problems. Some of the other pet parents had good luck with carafate (Sucralfate). However...I knew that both these meds are hard on kidneys.  What were the chances that we would have to deal with kidney values creeping up?  Especially when the vet only gave her 6 months...tops.  We took that chance and indeed the values are creeping up.  For the first time in 3+ years Chica is having to take some time off from the piroxicam because of this.  Not from stomach problems or ulceration but from creeping kidney panel values. I think we made the right choice from the beginning.  We will deal with this little setback. "Every little step backward leads to an extra step forward...so don't be discouraged." I  AM  NOT  DISCOURAGED!!! We will take each day and make the most of it...good, bad...we'll take it all.  We will flip a dew claw at this devil called TCC.  It WILL win in the end....but it will NOT be because we let it win easily.  As long as Chica is fighting we will fight for her and with her. ChicasMom, Lynn ChicasMom Sat, 29 Sep 2012 00:00:00 GMT Hi.  Also glad to hear Bailley is on the rebound.  Keep us posted on how it goes for him/her and the neoplasene! We had a scare earlier in the week when our scottie dog, Megan, had a toxic reaction to the piroxicam, and I was low on funds earlier this week. Fortunately the vet tech at my 2nd vet's office told me about a line of credit/credit called Carecredit.com , offered by GE, that allows someone to charge doctor/vet bills for up to 6months interest free if paid off in full.  Had anyone heard of this? If like me you are facing some short term emergency expenses that are difficult to pay for in full upfront, it may help.  I was able to get pre-approved and get Megan seen by my other vet quickly.  The second vet has now prescribed Megan some succinate (?) before eating, as well as 20mgs of pepsid to help counteract gastro intestinal side effects of using piroxicam. The vet said as well that some kind of acid reducer should always be taken with piroxicam. My dog's also on half the amount of antibiotic again (about 125 mgs a day, about average for a 30 lb dog), with a break from the piroxicam for a few more days before we try to restart Megan on it, but alternating every day.  She is eating very well, and I cook more for her now. Megan seems so much more comfortable when she's not on piroxicam, though, so we'll be careful administering it to her. I wonder how our doggies must feel on the stronger chemo drugs.  I don't know if I want Megan to go down that road.  In any case, fortunately (cross fingers/hold thumbs, hold my breath) my dog's blood work is normal right now, no liver or kidney functions impaired. Take care of yourselves and your little ones. Cathtalk Sat, 29 Sep 2012 00:00:00 GMT That is great news.  MinnieMo Sat, 29 Sep 2012 00:00:00 GMT Amazing Bailey has rebounded from the pancreatitis and is getting stronger every day.  We were at UPENN on Thursday and I now have the Neoplasene in hand!  We are awaiting results of the urine culture, but should hopefully be starting the dosage next week after she finishes the last bit of Baytril. Some of the doctors are very excited to see what the Neoplasene does.  I will post with updates as we go along. Baileysmom97 Sat, 29 Sep 2012 00:00:00 GMT It is so difficult, I will call when I get back into town. Karin karincam1 Tue, 25 Sep 2012 00:00:00 GMT I know I was not on the forum long, just a month before Sadie passed on, but I have to thank all of you for your prayers, words of wisdom about this horrible disease and encouragement. I honestly not sure I could have made it through a few days without knowing you all understood.  The article I shared about Pet Loss has a statement in it that I found so very true.  Dealing with the loss of a pet when others devalue your loss One aspect that can make grieving for the loss of a pet so difficult is that pet loss is not appreciated by everyone. Friends and family may ask “What’s the big deal? It’s just a pet!” Some people assume that pet loss shouldn’t hurt as much as human loss, or that it is somehow inappropriate to grieve for an animal. They may not understand because they don’t have a pet of their own, or because they are unable to appreciate the companionship and love that a pet can provide. Don’t argue with others about whether your grief is appropriate or not. Accept the fact that the best support for your grief may come from outside your usual circle of friends and family members. Seek out others who have lost pets; those who can appreciate the magnitude of your loss, and may be able to suggest ways of getting through the grieving process. "The best support for your grief may come from outside your usual circle of friends and family members" That is all of you and I thank you from the bottom of my heart. Sadie would have loved everyone of you.  MinnieMo Tue, 25 Sep 2012 00:00:00 GMT Hi Karen, I sent you a private message also.  I also want to thank everyone for their comments and prayers.  It definitely was the hardest thing I have ever had to do. You know I was like the rest of you in the beginning.  Trying everything, reading anything I could find.  Buying all the supplements and other foods that would be good for her.  After chemo quit working, and the continued UTI's, she didn't want to eat.  I couldn't get any of that stuff down her anymore.  I was constantly trying stuff every day. She lost 6 lbs the last month.  Next month would have been a year when the uti's started with diagnosis on Jan. 2. I wish the best for all of you who still have your baby. I pray you will know when it is time and have peace in the decisions you make. Praying for you all. Susan, Chloe's mom Chloebeaglemom Tue, 25 Sep 2012 00:00:00 GMT Hi Lynn (and Chica!) I can't thank you enough for replying! I am in Texas now, although I live most of the time in Switzerland. So I am seperated from my husband and making these decisions. I am concerned about the costs, especially if it is only short term. I saw where one post sugested that Dr. Cerf in NJ gave them an estimate for 7000 to 8000 dollars. We have already gone through chemo in Switzerland, and the thought of putting Em through more procedures, the expenses, and then to find out it might be only for a month or two and the tumor can return, meaning that we are right back here. But, your sweet message has definately given me information that I wanted and hearing that Chica continues to be strong is amazing! Thanks again and best wishes to you both! Karen LittleKaren Mon, 24 Sep 2012 00:00:00 GMT Hi "LittleKaren", I just had to respond to your post. Chica had a laser ablation done at Texas A&M on November 2, 2011 and she is STILL peeing quite nicely.  When we went in for the consult, she was just dribbling and was almost ready to stop peeing altogether so we had to make haste in getting to Texas (from N.C.).  It was well worth it...also...Chica was the smallest dog that they did an ablation on...so I guess you can say we opened up that frontier. When you think about it...1 year is a large percentage of our pets lives...so the laser ablation was good for Chica. When we first started this journey on July 14, 2009, I never in a thousand...no make that...a million years, thought that we would be still at it in 2012.  After all, in 2009, Chica was only 6 years old.  I never gave up!  I set a goal of getting Chica to her 7th birthday (and still be in good shape and feeling more than decent)...that came and I set another goal...to get her to her 8th birthday...that also came.  New goal...9th birthday...yup...came and new goal, 10th birthday in April of 2013. Will we actually make it?  Maybe, maybe not.  I can't second guess when she will take that downward spiral.  I can only wait and if it does happen, I will do what I know I have to do, with a very heavy heart.  I do know, however, that we will make every additional day count...live it to its fullness (making believe, for Chica's sake, that she is NOT ill).  That, and medical intervention, good food, supplements, love and lots of prayer to St. Francis,  has taken us this far. Every morning I get up and look at my dresser...there is a saying on it (that has been there from the start of this journey): "Hope is the companion of power and the mother of success.  For those of us who hope strongest have, within us, the gift of MIRACLES."   -sydney bremer A little over a year ago I added another saying: "Every little step backward leads to an extra step forward.......So don't become discouraged." Take heart...don't get discouraged...renew your fight...Emily is worth it. ChicasMom, Lynn ChicasMom Mon, 24 Sep 2012 00:00:00 GMT Hi Susan, I sent a private message also, but just wanted you to know how sorry we are for your loss of your beagle, Chloe! I followed your posts especially because our beagles seem to be the young ones here. We are coming up on 1 year diagnosis (October 1) and Em has large mass now growing in her urethra. I can't tell you how much it breaks my heart to read about Chloe and please know we are think of you and her! Karen, Emily' and Murphy's mom LittleKaren Mon, 24 Sep 2012 00:00:00 GMT Susan, I am so sorry for you. Heart broken and lost for words but sending our thoughts and love. Poppy and Esther. poppy06 Mon, 24 Sep 2012 00:00:00 GMT Hi Cory, I just went to Texas A&M to consult there for having the laser ablution done on my Emily. I have been off of this site for awhile as Emily was without symptoms and we had gone through chemo. However, it has been a year and she has developed a tumor right at the opening of the urethra and they were surprised she could urinate due to the size and location. I have an appointment for the laser ablution, but wasn't sure about the long term prognosis. At A&M they indicated that results varied depending on the aggressiveness of the TCC the dog has and the growth rate? They talked about the vet you are seeing and gave me the website to watch the procedure. But, I wondered about the time it takes for the tumor to reappear? We have followed Dr. Dressler's Cancer diet and seem to be doing well for the year post diagnosis. But this recent tumor has thrown me for a loop. Em has NO symptoms...no infections, no straining, no blood...nothing. Perfectly healthy...so it is horrible to think I might have to say good-bye to an otherwise healthy and young sweet beagle. She is only 7! Any info on this procedure would be much appreciated!! I think of all the other dog owners and thier pups going through this constantly, and wish there was more we could do to help! LittleKaren Mon, 24 Sep 2012 00:00:00 GMT Yes the way the messages are delivered is confusing. Our Sadie was a black lab, Cloe is a beagle.  No apology needed, it can all be so confusing and mind numbing, just trying to deal.  Also I really wish this forum had an edit feature.  MinnieMo Sat, 22 Sep 2012 00:00:00 GMT Thank you for the suggestions.  I rubbed a damp cloth on her stomach last night and that seemed to help. The area of the rash was on her lower stomach, also near her hind legs.  I suspect the rash is medication related, or to the cancer.  She rubs her stomach alot on the floor even more than usual (she gets skin allergies frequently).  The rash seems to have flared up and faded. I'm worried by it and will put in a call to the vet when I get home in an hour or so.  Hopefully she'll come back to me. I think I confused your dog, Sadie, with Chloe, the other day.  I apologize for this.  I think the headings and the messages within messages sometimes causes this. Cathy Cathy Thanks again. Cathtalk Sat, 22 Sep 2012 00:00:00 GMT I would not give Benadry with the other medications without talking to your Vet. When you say rash, where was it located.  With TCC, our Lab had red inflamed skin in the area between her hind legs where there is little area. This was due to the cancer. I did find spraying her with Vetricyn topical spray gel did help.  For fever, apply cool towels to her belly or wrap her in a cool towel, if you have a fan, you can use that too. Feed her ice chips.  MinnieMo Sat, 22 Sep 2012 00:00:00 GMT Hi everyone. My dog Megan's now been on piroxicam for about a week and 4 days, as well as on another course of clavamox for an infection. She suffered a rash about two days ago -- I had walked her earlier in the day, and I wondered at first if her usual allergies hadn't erupted.  I rubbed benadryl over her stomach, which she licked off.  But by the evening, the rash had diminished.  I was debating whether I could safely give her some benadryl.  I cannot find out if it is contraindicated with piroxicam, so I held off giving it to her. The last two or three days, her energy level has varied alot over the course of the day.  However, I'm worried tonight as I can tell she has a temperature -- her nose is warm, bordering on hot.  I haven't got a thermometer for her yet and don't know how I can bring her temperature down, except maybe putting some witch hazel on her stomach -- I'm out of diaper wipes!  Any suggestions from anyone on this forum would be really appreciated by both of us! Thank you! Cathtalk Sat, 22 Sep 2012 00:00:00 GMT I got dip sticks, little sticks I would saturate with urine... if the color changed for presence of white blood cells, (Leukocytes) I know there was an infection. Huey had one in the very begining, then there was just presence of blood on the dip stick. This way I knew if it was just blood, or an infection. karincam1 Sat, 22 Sep 2012 00:00:00 GMT Gabriel has basically had an infection since March that never completely went away. We finally got him on an antibiotic that did something,but after being off of it for a week or so the infection came back worse than ever. Now our vet is just leaving him on the antibiotic long term. His white blood count has dropped quite a bit from the chemo so I'm just worried that the chemo is making the infection worse. Needless to say I am very confused as to what I should do. i don't want to do anything to make him feel worse. triciac Fri, 21 Sep 2012 00:00:00 GMT Sadie would run fever when she had a UTI and the blood in the urine increased.  With TCC, it is very hard to tell the symptoms from TCC or UTI, which of course is why it is hard to diagnose.  After we found out Sadie had TCC, I took her temp when I noticed her urine getting dark.  MinnieMo Fri, 21 Sep 2012 00:00:00 GMT I just wanted to send my best wishes to everyone in the group, especially to the families of Chloe and Huey. It is hard to read about each other's struggles, but so helpful at the same time. Your courage at facing this disease is admirable. Siena had her monthly checkup today. I was a bit concerned because she's seemed under the weather lately, but I got good news that her tumor is slightly smaller. This is her 5th month on neoplasene and the tumor has steadily shrank over that time. Progress has been slow, its never shrinks dramatically or anything, but I'm ok with it because at least its a small step in the right direction. I do think she is having a slightly upset stomach from the medicine, but she still eats and takes her meds with no problem. I am going to start feeding her three tiems a day (instead of two) to spread out the medicine and gopefully help her feel normal again. I've been worried about UTIs as well. I haven't noticed any, but am not really sure what to look for... I'd be interested to hear how you know when your dog has one, what symptoms to watch for, etc. Thanks, jenn SienasMom Fri, 21 Sep 2012 00:00:00 GMT We haven't tried chemo, but Tiny Tot has been battling UTIs since January. Everytime he was done with his antibiotics, he'd have problems within a week, and back on. It was in April that the vet finally started thinking it might be cancer, and he was diagnosed in May. He started taking Piroxicam in June, and we left him off antibiotics for about a month to see, because he was doing ok without them. We just put him back on again because of blood in his urine and straining a lot more. We'll probably just keep him on Piroxicam & antibiotics for the rest of his life (or at least always have antibiotics on hand to catch the UTI at the first symptoms). I give him yogurt to help give back some of the good bacteria that the antibiotics are killing, and it seems to make his tummy better, too. TinysMom Fri, 21 Sep 2012 00:00:00 GMT UTI's seem to be par for the course.  My doctor said that the cancer interrupts the mucosal lining and therefore, the bladder becomes more susceptible to infections.  If your dog can tolerate the antibiotics well, it should not be a problem with continuing the chemo.  My dog, Bailey has had 6? in the last year and a half...we tried chemo once and she did not respond well to it and the tumor never changed. Karin Baileysmom97 Fri, 21 Sep 2012 00:00:00 GMT Hi there. My dog,Gabriel, was diagnosed in July. He first started having symptoms back in February. I was just wondering if anybody has dealt with chronic UTIs? We have been doing the chemo,but I'm really unsure with this infection if we should continue or not.                           Tricia triciac Fri, 21 Sep 2012 00:00:00 GMT Thank you. I hate to see others going through this pain. My heart breaks for you, Karin karincam1 Thu, 20 Sep 2012 00:00:00 GMT So sorry to hear about Huey and Chloe.  I think we all cry when we hear about our beloved companions leaving us, but hope that they will indeed be in a happier place. Bailey and I send our thoughts and prayers. Baileysmom97 Thu, 20 Sep 2012 00:00:00 GMT Susan, I am so sorry about Chloe.  Everytime one of our beloved pets leave us...I feel your pain.  It hurts me as if they were my own...because I fought, with all my might, right along with you. I cry...for ALL that have gone before...and for ALL that are waiting...waiting...waiting... Please know that I will pray, that you will find peace in knowing you did all you could for her. Remember the good days! ChicasMom, Lynn ChicasMom Thu, 20 Sep 2012 00:00:00 GMT I am so sorry, i was there just 5 days ago. It is so painful, but I just sat and looked at Huey, and how peaceful he was, and I knew I did the right, and humane thing. God be with you, and comfort you. Please feel free to Message edited by CancerCompass staff. For personal protection,email address removed. Consider private reply. Please review CancerCompass Member Guidelines athttp://www.cancercompass.com/common/guidelines.html  Karin karincam1 Thu, 20 Sep 2012 00:00:00 GMT Indeed it is cruel. I saw how he struggled, each time he went potty. So sad. We are both at peace, now. Thank you, Karin karincam1 Thu, 20 Sep 2012 00:00:00 GMT Also thinking of you and Chloe and wishing, hoping all is peaceful for you both as she passes!  She'll always also rest in your heart forever. Sorry for you both.  Cathy Cathtalk Thu, 20 Sep 2012 00:00:00 GMT I'm so sorry. I just walked by Shelby's ashes box today snd gave it a kiss. You are doing the right thing. You don't want her to suffer. We're all doing enough suffering without them. We love them so much and miss them so much but I feel they look to us for help and sometimes it's difficult to do it but it's the loving thing to do. My heart aches for you. She will love you til the end though and that's you're doing. Shelby was so calm I thought it meant she was ready. I pray for you. So sorry. Shelbysmom2 Wed, 19 Sep 2012 00:00:00 GMT Prayers for both of you.  MinnieMo Wed, 19 Sep 2012 00:00:00 GMT Karin, Hi. I'm so sorry about Huey.  What a cruel disease.  Please take care of yourself and know that others are thinking about you. Love, Nita Nita Wed, 19 Sep 2012 00:00:00 GMT Susan my friend, I'm so sorry to hear about Chloe. It's hard to hold back the tears.  You are in my thoughts and prayers. Love,  Nita Nita Wed, 19 Sep 2012 00:00:00 GMT I am crying with you.  Iloverio Wed, 19 Sep 2012 00:00:00 GMT Well it looks like the time has finally come that Ive been dreading. Chloe was real restless last night. This morning she is real lethargic with labored breathing. I carried her to the couch and am sitting with her. I did get her to drink some water and eat some chicken. The prednisone had her eating again. The Dr. and his assistant are coming around 5. She seems to be suffering and we don't won't her to end up dying a violent death from a stroke or heart attack. So we have about 4 hrs left to be together. All I can do is sit here and cry. Susan Chloebeaglemom Wed, 19 Sep 2012 00:00:00 GMT I'm so sorry about Sadie-- I have no words of advice, just know that I'm thinking about you and praying for you and Sadie when things are so tough.  This forum has been a huge help to me too, buty the one thing that is hard is seeing such dedicated and loving people "companions" as they have to go through something so difficult (and knowing that I'll have to endure it also some day).  Please take care of yourself. Hugs,  Nita Nita Tue, 18 Sep 2012 00:00:00 GMT "Any advice would be greatly appreciated. Love to all of you who are going through this horrible experience and to all your little babies xxx" Hi Anne. I'm facing the same uncertainties with my scottie dog. She's only 6 1/2 years old, diagnosed formally with tcc finally with the bladder test, and she's very much a part of my family and really the equivalent of a child for me.  I'm worried about what more I can do for her and also what I think I should eventually not do. My older cat's veterinarian gave me some good advice last year when she/the cat lost her ability to keep her balance and walk and tests weren't able to determine what the cause was.  The vet recommended immediately keeping a daily diary my cat, noting what her day was like, what she was and wasn't able to do, how well was she eating, sleeping, whether she could go outside, etc. In other words,  the vet was telling me to record/observe my cat's quality of life from day to day, so as to eventually provide me with some tangible basis to track and objectively compare her health in minute detail from week to week, or even day by day.   The vet said not to fill the diary with emotions or feelings, but just concrete observations.  And that's just what I did. I found this record keeping helped me tremendously and I was able to decide at a certain point that it was time to end my cat's suffering and and let her go.  Without the notes and the diary, I would have likely postponed making that awful, painfully hard decision.  Of course I still miss her awfully. I started a diary yesterday for my dog, too.  I've started noting how her energy level is, how well she breathes, her appetite, how often she needs to go to the bathroom, how long it takes her to go, how often and how many times is she is licking, scratching in the course of an hour even!  It's tough if one has to work all day and if one is not on hand to observe as much of Sadie, but try it!  Ask friends and family members to help, too.  Take lots of pics, pamper her, and give her loads of attention, too, and see how she responds.  But observe and keep that diary.  Go back over it in a week's time and try to note what similarities or differences you discover. Hope this helps.  Cathy Cathtalk Tue, 18 Sep 2012 00:00:00 GMT On Sep 18, 2012 4:58 PM coryrajotte wrote: Hi. I have a male min pin Hank 13 years old who has lived with TCC for over a year. He is on chemo and a mixture of holistic drugs. He is doing great and the tumor is growing very slowly towards his urethra. I took him to Dr. Cerf at the Ridgewood Veterinary Hospital in February this year. Here is the info: Ridgewood Office | 320 E. Ridgewood Ave. Ridgewood, NJ 07450 | phone: (201) 447-6000 I will have the laser ablation surgery done when he can no longer urinate and the cancer spreads into the neck of his bladder or urethra. He goes in with a laser and removes the tumor. This way it doesn't seed the tumor and metastasize it.  He is the only Dr. that specializes in this type of surgery and has been doing it for 10+ years. My dog is my baby and I have took him to several different specialists, granted we live in S. Texas so we have been all over and Dr. Cerf has been the only Dr. that has given us any hope and has made Hank's life more comfortable until he is ready for surgery. If we had a female dog he would have already done the procedure because it is much easier. So if it were me I would call them, have all of her ultrasound images and medical records sent over and get a consultation. Dr. Tara Johnson works with Dr. Cerf and is who I originally spoke with. He is insanely busy because people from all over the US are coming to him and having this procedure. This usually extends their life for another year or in some cases 3 years. Females are more successful than male dogs. Let me know if I can help and I feel your pain, I have agonized over the thought of losing my little boy for the last year. Luckily he is still a happy boy and his quality of life is still good. My thoughts are with you...I just wanted to point out that laser ablation is not the end all cure.  I too had seen Dr. Cerf and he was wonderful and extremely generous with his time, but the procedure is extremely expensive (about $7 to 8k) and there is no guarantee that the tumor does not come back.  The problem is that even with the laser, there is no way to completely remove the tumor from the bladder wall and thus it can always come back.  He told me in some cases people do the procedure a few times!  There was one dog whose tumor came back after only a month.  If money is not a factor, then this is certainly worth considering. Baileysmom97 Tue, 18 Sep 2012 00:00:00 GMT On Sep 18, 2012 4:58 PM coryrajotte wrote: Hi. I have a male min pin Hank 13 years old who has lived with TCC for over a year. He is on chemo and a mixture of holistic drugs. He is doing great and the tumor is growing very slowly towards his urethra. I took him to Dr. Cerf at the Ridgewood Veterinary Hospital in February this year. Here is the info: Ridgewood Office | 320 E. Ridgewood Ave. Ridgewood, NJ 07450 | phone: (201) 447-6000 I will have the laser ablation surgery done when he can no longer urinate and the cancer spreads into the neck of his bladder or urethra. He goes in with a laser and removes the tumor. This way it doesn't seed the tumor and metastasize it.  He is the only Dr. that specializes in this type of surgery and has been doing it for 10+ years. My dog is my baby and I have took him to several different specialists, granted we live in S. Texas so we have been all over and Dr. Cerf has been the only Dr. that has given us any hope and has made Hank's life more comfortable until he is ready for surgery. If we had a female dog he would have already done the procedure because it is much easier. So if it were me I would call them, have all of her ultrasound images and medical records sent over and get a consultation. Dr. Tara Johnson works with Dr. Cerf and is who I originally spoke with. He is insanely busy because people from all over the US are coming to him and having this procedure. This usually extends their life for another year or in some cases 3 years. Females are more successful than male dogs. Let me know if I can help and I feel your pain, I have agonized over the thought of losing my little boy for the last year. Luckily he is still a happy boy and his quality of life is still good. My thoughts are with you...wow! thats great to hear he is still with you!! I have heard so much about Ridgewood Veterinary Hospital particularly when I was scouring the internet for hours upon hours as we all do when something like this happens. It kills me that I am over the other side of the world in Ireland, I would do anything to get her over there just as a final option. The veterinary hospital here which was dealing with her have been great, they are as frustrated as us that there are so few developments for this kind of cancer, they used to love Sadie's visits as she would stand up on her back legs begging whenever they spoke to her. Her nature tends to melt everyones hearts! The main thing is keeping them comfortable and I'm so glad to hear they are keeping Hank comfortable. Whilst I may be over in Ireland, I would be really interested in keeping up to date with Hanks progress - its such a horrible disease that its good to hear some stories of hope! I wish you all the luck in the world for you and your baby <3 xxxx anne19830 Tue, 18 Sep 2012 00:00:00 GMT On Sep 18, 2012 4:38 PM karincam1 wrote: Beyond painful, is the best way to describe it. I said good-bye to Huey, just 5 days ago. He had a horrible night, the night before he passed. Panting, pacing, unable to settle down, and sleep, it was very clear he was unable to continue. Up until the ned, he was eating great, and loved his treats. The hardest part for me was acknowledging everything was good with this 12 1/2 year old by, except his bladder... that was hard. He ran outside thinking he had to go, and he would pee drops... only to run outside again 5 minutes later, thinking he had to pee again. I said good-bye here at my home, so all my other dogs knew he was gone. I am happy I did that, they are all doing fine. I miss him terribly, but he has given me peace, for I believe he has been given a new body, a new life in Heaven. I have 3 other senior dogs, all over the age of 12, and know I will be facing this again soon. But, the joy they have given me, far outweighs the heartache of their passing. There are dogs all over this country, who will be killed today, healthy, young dogs, who will die alone, never knowing they were loved. Take comfort in the love you shared, and when it is time, save a life of a dog doomed to die. It will heal your heart. God blees you, may you know peace, and comfort in these diffucult days. I watched Huey after he passed. He looked so peaceful, so pain free. I know it was the right thing to do. Karinthanks so much for taking the time to reply and i'm so so sorry for your loss particularly as it must be so raw for you right now. It means a lot that you came here to respond to me even though you are going through so much.  You are so right, I think the hardest part is seeing how good they are in all other aspects - it really only hits you when you see them straining. Your situation sounds exactly like what I'm having with Sadie....she usually can get a couple of urinations out, maybe 1 or 2 then its just drops. Walks are the worst....they help her mentally but she stops every two seconds and I cant even imagine what that must be like. I keep wondering, is she used to it now or is it painful everytime. Its so hard to know.  What you did was the right thing to do.....our babies rely on us to make a decision they can't and your so right, all those beautiful healthy dogs that day in day out have to die needlessly - our ones have been very lucky and so have we. I really appreciate your response particularly considering the fact it is so recent but I am glad to know you have some peace. I will keep you all posted, thanks again and sending you much love, you are in my thoughts xxxx anne19830 Tue, 18 Sep 2012 00:00:00 GMT Some people do not understand the grief after losing your pet. I wish there was a way to honor a grieving period for pet loss, like family. I had to work the next 2 days, and it was very hard. if I called in sick, I would have been written up. There is no "funeral leave" for a pet, even when it is like my child. I wish this would change. Thank God for those who undersatnd, and allow us to vent our feelings, and not judge. karincam1 Tue, 18 Sep 2012 00:00:00 GMT On Sep 18, 2012 4:20 PM Iloverio wrote: I am so sorry, Annie.  I have not posted much (except for private replies) since I lost Rio almost 4 months ago.  I think everyone's experience is unique, but in our case it was the lethargy and loss of appetite (plus vomitting what little he did eat) which took Rio in the end.  I made the same promise to him as you made to Sadie.  But that is easier said than done.  When I the bad days far outweighed the occasional normal day, I decided that I could do something to ease his pain and that I must stay true to my word.  This is different for everyone.  People kept telling me that I would know when the time came, but it is hard to know for sure.  I miss my dog everyday, but now I am starting to think of the happy times we shared.  His sweet spirit will never leave me.  I want you to know that whatever you decide, you are making the right decision.  God bless you and Sadie.thank you so much for your lovely response, i know how hard it must be to come back on here after what you have gone through and im so so sorry for your loss. It truly is like losing a family member. I think you are right, you need to measure up the good days vs the bad. We've been here before, times when we think 'this is it' then she bounces back. But at the same time, thats the problem, on the outside you cant tell how bad they are internally. How I wish they were blessed with a voice! I have the utmost respect for you for making that decision, it is always the right decision just so so difficult but we have to do it for them. I'll be sure to keep everyone posted but thank you so much, it really means the world to me speaking with people who know how this feels. Thinking of you xxx anne19830 Tue, 18 Sep 2012 00:00:00 GMT Hi. I have a male min pin Hank 13 years old who has lived with TCC for over a year. He is on chemo and a mixture of holistic drugs. He is doing great and the tumor is growing very slowly towards his urethra. I took him to Dr. Cerf at the Ridgewood Veterinary Hospital in February this year. Here is the info: Ridgewood Office | 320 E. Ridgewood Ave. Ridgewood, NJ 07450 | phone: (201) 447-6000 I will have the laser ablation surgery done when he can no longer urinate and the cancer spreads into the neck of his bladder or urethra. He goes in with a laser and removes the tumor. This way it doesn't seed the tumor and metastasize it.  He is the only Dr. that specializes in this type of surgery and has been doing it for 10+ years. My dog is my baby and I have took him to several different specialists, granted we live in S. Texas so we have been all over and Dr. Cerf has been the only Dr. that has given us any hope and has made Hank's life more comfortable until he is ready for surgery. If we had a female dog he would have already done the procedure because it is much easier. So if it were me I would call them, have all of her ultrasound images and medical records sent over and get a consultation. Dr. Tara Johnson works with Dr. Cerf and is who I originally spoke with. He is insanely busy because people from all over the US are coming to him and having this procedure. This usually extends their life for another year or in some cases 3 years. Females are more successful than male dogs. Let me know if I can help and I feel your pain, I have agonized over the thought of losing my little boy for the last year. Luckily he is still a happy boy and his quality of life is still good. My thoughts are with you... coryrajotte Tue, 18 Sep 2012 00:00:00 GMT Beyond painful, is the best way to describe it. I said good-bye to Huey, just 5 days ago. He had a horrible night, the night before he passed. Panting, pacing, unable to settle down, and sleep, it was very clear he was unable to continue. Up until the ned, he was eating great, and loved his treats. The hardest part for me was acknowledging everything was good with this 12 1/2 year old by, except his bladder... that was hard. He ran outside thinking he had to go, and he would pee drops... only to run outside again 5 minutes later, thinking he had to pee again. I said good-bye here at my home, so all my other dogs knew he was gone. I am happy I did that, they are all doing fine. I miss him terribly, but he has given me peace, for I believe he has been given a new body, a new life in Heaven. I have 3 other senior dogs, all over the age of 12, and know I will be facing this again soon. But, the joy they have given me, far outweighs the heartache of their passing. There are dogs all over this country, who will be killed today, healthy, young dogs, who will die alone, never knowing they were loved. Take comfort in the love you shared, and when it is time, save a life of a dog doomed to die. It will heal your heart. God blees you, may you know peace, and comfort in these diffucult days. I watched Huey after he passed. He looked so peaceful, so pain free. I know it was the right thing to do. Karin karincam1 Tue, 18 Sep 2012 00:00:00 GMT I am so sorry, Annie.  I have not posted much (except for private replies) since I lost Rio almost 4 months ago.  I think everyone's experience is unique, but in our case it was the lethargy and loss of appetite (plus vomitting what little he did eat) which took Rio in the end.  I made the same promise to him as you made to Sadie.  But that is easier said than done.  When I the bad days far outweighed the occasional normal day, I decided that I could do something to ease his pain and that I must stay true to my word.  This is different for everyone.  People kept telling me that I would know when the time came, but it is hard to know for sure.  I miss my dog everyday, but now I am starting to think of the happy times we shared.  His sweet spirit will never leave me.  I want you to know that whatever you decide, you are making the right decision.  God bless you and Sadie. Iloverio Tue, 18 Sep 2012 00:00:00 GMT Hi all, Firstly I just want to say this forum has been an absolute god send for me over the past few months. Its so lovely to see so many people sharing their stories, their suggestions and supporting one another through such a horrible time. And yet it scares me, because its only now I'm brave enough to post. Everytime I come on I cry because it means having to accept the inevitable. To all those who have lost their dogs to this horrible disease i want to send you hugs because I know myself the time is looming and its the worst pain I've felt in years.  5 months ago, my gorgeous girl and best friend Sadie was diagnosed with a tumor within the neck of her bladder. Our vet told us there was no surgical option and that we would have to accept that this will just grow and eventually take her from us. He advised against chemotherapy however we wanted to try everything, providing she was not uncomfortable. Sadie went on to have 5 sessions of chemo....most did not affect her negatively bar her second last one with made her extremely sick. At her scan after her last chemo we were told the tumor had not grown but that it hadn't shrunk at all and was unsuccessful. It killed us. We now had to admit we were fighting a losing battle, that was 6 weeks ago. Sadie is also on metacam which I do feel has helped her greatly. We also give her a mixture of cottage cheese and flaxseed oil (Budwig diet) and that does seem to have helped slightly.  Unfortunately though, within the past week she has slowed down considerably. We had her 8th birthday last week which was incredibly emotional. We know its the last one she will ever see. She is still straining to urinate but does usually get a least one normal urination out a day but the rest are just droplets. She vomitted yesterday and has spent the last few days very lethargic with no appetite (apart from the odd treat) so we don't know if this is the beginning of the end or if she just has a bad reaction in her tummy. Either way, I do feel like the time is drawing near and I'm really not ready. Nothing prepares you to say goodbye. Nothing. I have never loved a dog as much, Sadie was a stray and the best thing to ever walk into my life. She follows me everywhere, she sleeps with me, in fact she would nearly talk to you if she could preferring human company over our other 2 dogs. She has the most beautiful personality and whenever anyone in the family is sick she will never leave their side for a minute. She is being so strong and so brave and I made a promise I would never let her suffer yet I don't know what to do. The straining has been the same since day 1 although it is now slightly more frequent but mostly on walks but the sickness and loss of appetite is worrying me. Has anyone experienced this and would this be considered a reaction to her meds or the beginning of her decline? I will of course be discussing this with our vet but I would prefer to hear from people who have or are going through this themselves. This is by far, the most difficult few months of my life. I've lost so many people in my life in the past but this just seems so different, knowing that no matter how full of energy she can be when she bounces back I will inevitably have to make the decision to end her life at some point when shes the most important thing in it. Any advice would be greatly appreciated. Love to all of you who are going through this horrible experience and to all your little babies xxx anne19830 Tue, 18 Sep 2012 00:00:00 GMT I give Tiny about a teaspoon of yogurt in his evening meal. He's back on antibiotics due to blood in his urine again, and he's been on piroxicam every other day for almost 2 months now. It seems to keep his tummy happy and gives back some of the good bacteria that is also being killed by the antibiotics. TinysMom Sat, 15 Sep 2012 00:00:00 GMT Slippery elm powder is very good for protecting the digestive tract & beyond when taking  these types of meds. I always keep this stuff handy even for me  tryeverything Sat, 15 Sep 2012 00:00:00 GMT Make sure you add Pepcid, or some anti-acid medicine with Peroxicam. karincam1 Fri, 14 Sep 2012 00:00:00 GMT Thanks to all for the good wishes.  Bailey continues to improve each day.  She's not yet back to running around the park but we may try to go for some short walks this weekend.  I have to say my local vets were just awesome...they even gave me their own cell number in case I had problems at night.  The one thing I could not believe is what one of the doctors at the hospital said to me--"Well she's had this cancer so long she won't live much longer, so your options are somewhat limited."  I get that this cancer is such a beast, but you never ever know how long a dog will live.  Some dogs have beaten the odds and some have not.  I think we've all learned just to take this one day at a time and make the best of it for whatever time we have. Baileysmom97 Fri, 14 Sep 2012 00:00:00 GMT Glad to hear this.  MinnieMo Thu, 13 Sep 2012 00:00:00 GMT Also glad to hear the good news. I hope Bailley will regain some of his/her strength, after all of what has happened, and that the new medication will help more.  Cathy Cathtalk Thu, 13 Sep 2012 00:00:00 GMT On Sep 11, 2012 5:57 PM Baileysmom97 wrote: Well I am happy to report Bailey came home from the hospital Friday night and is doing relatively well.  She went in Wednesday morning for 24 hr IV fluids and meds.  She is still pretty weak, lost a fair amount of weight but is hanging tough.  They think she had a mild case of pancreatitis and possibly another UTI.  Kidneys appeared good on the ultrasound, so that was a relief.  She also seems to still have a bit of neck and back pain from somersaulting off the bed.  Her specialist now has the Neoplasene on hand so hopefully once she gets stronger we will be able to start that.  It's just been a nightmare the last week.Hi-  So glad that Bailey is doing better!  Good news---keep us posted. Love, Nita Nita Tue, 11 Sep 2012 00:00:00 GMT Well I am happy to report Bailey came home from the hospital Friday night and is doing relatively well.  She went in Wednesday morning for 24 hr IV fluids and meds.  She is still pretty weak, lost a fair amount of weight but is hanging tough.  They think she had a mild case of pancreatitis and possibly another UTI.  Kidneys appeared good on the ultrasound, so that was a relief.  She also seems to still have a bit of neck and back pain from somersaulting off the bed.  Her specialist now has the Neoplasene on hand so hopefully once she gets stronger we will be able to start that.  It's just been a nightmare the last week. Baileysmom97 Tue, 11 Sep 2012 00:00:00 GMT MinnyMo, BailleysMom/Karin, Thanks SO MUCH to both of you for some good ideas -- the EGCG, and I'll keep the neoplastene(?) in mind too. Also, thanks for the link to this resource -- dog cancer diets. It looks really informative and I'm reading it now. Thank goodness for this forum. I'd be at something of a loss otherwise. As I type, my scottie's right next to me too near my feet. She often follows me from room to room. When I'm not around, she's got my mother and our small mau cat for company. I hope I still get to film the cat and scottie together at play one of these days, as they are hilarious and so oddly matched. (Picture a a slight, long legged, and quicker cat, nipping or swiping a short, stocky, bulky dog on the tail or even the face. The dog more often resorts to nudging and rearing up and down in the manner of a horse, when she plays withe cat). I like the picture of Sadie -- looking right back at you/the camera, glistening, looking young, too. She looks like she was always up for whatever you wanted to do, and it sounds as if you did alot together. Car rides/drive throughs are so much fun for them, aren't they? I guess it gave Sadie a chance to smell food and poke her head further out the window, maybe too. I do know what you mean about feeling as if Sadie's been "visiting" you in spirit. Even after losing an older sibling, I'd sometimes still hear a sort of wet, deep cough that I swear was her's. Other times, I'd smell her perfume in parts of the house. And sometimes, these visit feelings still occasionally happen for me, yars later, in lots of unexpected ways and I try to accept them when they do happen and let them make me feel connected to the moment. (I don't know if what I said makes sense.) So, I hope your strange occurrences of Sadie won't trouble you much in the times ahead. Take care and enjoy the fall weather! Cathy/Megan's 2nd mom Cathtalk Fri, 07 Sep 2012 00:00:00 GMT MinnyMo, BailleysMom/Karin, Thanks SO MUCH to both of you for some good ideas -- the EGCG, and I'll keep the neoplastene(?) in mind too.  Also, thanks for the link to this resource -- dog cancer diets.  It looks really informative and I'm reading it now.  Thank goodness for this forum.  I'd be at something of a loss otherwise. As I type, my scottie's right next to me too near my feet.  She often follows me from room to room.  When I'm not around, she's got my mother and our small mau cat for company.  I hope I still get to film the cat and scottie together at play one of these days, as they are hilarious and so oddly matched.  (Picture a a slight, long legged, and quicker cat, nipping or swiping a short, stocky, bulky dog on the tail or even the face.  The dog more often resorts to nudging and rearing up and down in the manner of a horse, when she plays withe cat). I like the picture of Sadie -- looking right back at you/the camera, glistening, looking young, too.  She looks like she was always up for whatever you wanted to do, and it sounds as if you did alot together. Car rides/drive throughs are so much fun for them, aren't they?  I guess it gave Sadie a chance to smell food and poke her head further out the window, maybe too.   I do know what you mean about feeling as if Sadie's been "visiting" you in spirit.  Even after losing an older sibling, I'd sometimes still hear a sort of wet, deep cough that I swear was her's.  Other times, I'd smell her perfume in parts of the house. And sometimes, these  visit feelings still occasionally happen for me, yars later, in lots of unexpected ways and I just accept them when they do. I don't think on them too much and let them make me feel connected to the moment.  (I don't know if that makes sense.) So, I hope your strange occurences of Sadie won't trouble you much in the times ahead.  Take care and enjoy the fall weather!  Cathy/Megan's 2nd mom   Cathtalk Fri, 07 Sep 2012 00:00:00 GMT Due to Sadie's advance stage of the TCC when they found it, we only had her on a medication similar to Piroxicam, and pain medications. Our oncologist did have Sadie on Tramadol for pain and Gabapentin which I have not seen anyone mention here. I have actually taken Gabapentin myself for shingles pain. Our oncolgist says she always uses it with tramadol for cancer pain. Sadie ate pretty good until the last week and we were never sure if it was due to the medications or the advancement of the cancer. Since she got critically worse shortly thereafter it could have been both. The tramadol seems to work well for pain management but has a bitter taste and pretty soon she refused to take it in food. In hindsight I would have asked for the flavored liquid version, as trying to get those pain pills down her was not enjoyable for either of us It was the first time ever, she did not want to be around me and broke my heart and hers too. She knew I was trying to help but she hated the taste and nothing could hide it. In fact in looking back I probably would have not put her meds in food, as pretty soon she began to associate food with meds and that was when she got recluctant to eat. Toward the end when she began to not want to eat she was on a medication for nausea.  MinnieMo Fri, 07 Sep 2012 00:00:00 GMT I'm so sorry about Sadie. I would love any information you'd share about keeping Sadie comfortable during the fight. Did you experience specific side effects that you figured out how to alleviate? SweetPeasMommy Fri, 07 Sep 2012 00:00:00 GMT Hi everyone, It's been a little while. I'm glad Bailey is feeling a little better. I wanted to post about Sweet Pea and maybe offer the group a bit of encouragement. Sweet Pea was officially diagnosed with bladder cancer on 6/30/12. She had been suffering from blood in her urine since the end of April, so the vet believes she has had the cancer since at least then. We immediately started her on chemotherapy and piroxocam. The first few rounds of chemo were a little rough--she was quite nauseous and would vomit and excrete clear mucous--with me being pregnant, this proved a bit difficult as it was hard to see. We perservered and started antinausea meds. She receives chemo every 2 weeks and is on piroxicam daily. After just 2 treatments (4 weeks) she went back in for an ultrasound and the tumor shrunk! We've continued the treatments and there is no longer blood in her urine (it was bad at a point), she has pep in her step, and the cloudiness in her eyes has cleared. Everyday I look at her and notice that she isn't as tired anymore and just generally seems like a puppy again. Of course, I know we all can't be around forever, but watching how much better she looks (and obviously feels) has reassured me that we made the right decision to treat as aggressively as we could with her (surgery was not an option because she is so small). I just wanted to share our battle so far for all those looking for stories or possible treatment options for your little pal, I know it was a very hard decision for me to make for my girl, and when I look into her eyes today, I know she tells me thank you. For 68 official days (128 if you count the 2 months before), we've been fighting, and, so far, prevailing. It's a long road ahead, but Sweet Pea and I will walk the road together. My thoughts go out to all. Sweet Pea's Mommy SweetPeasMommy Fri, 07 Sep 2012 00:00:00 GMT And it drives me crazy this forum will not let you edit your postings. Typos and misspellings are due to tears, which I am sure everyone understands.  MinnieMo Fri, 07 Sep 2012 00:00:00 GMT If I can figure out how to share a photo, I will. I pray daily for all of you still dealing with this and those that have already lost their beloved pet.  Yes we are still in shock. It is just so very hard to release she is gone and will not be laying at my feed when I am here on the computer. The other night I thought I heard her snoring.  I have also had two strange occurances since Sadie died, that friends say are visits from her. I don't know what to believe but if she is letting me know that she is now out of pain and can run and play, I am glad.  I just would love to have the chance for one more hug.  If I can be of any help to anyone going through this please ask. It does help, to help others. I did a lot of research on TCC while Sadie was sick and I am trying to let others know about exposure to lawn chemicals and more natural flea and tick treatments.  I would highly recommend reading the Dog Cancer Survival Guide, it was a wealth of information and helped me stay focused on keeping Sadie comfortable.  This is the link to the diet they recommend. http://dogcancerdiet.com/pdf/DogCancerDiet.pdf MinnieMo Fri, 07 Sep 2012 00:00:00 GMT We would have never let Sadie suffer with this horrible disease, so we knew from the onset what the outcome would be. We were just in shock that she went from a healthy vibrant 7 year old Lab, to what she was on the day we let her go.  Our oncologist and our Vet said they had never seen such an agressive case of TCC before, so we feel she had it pior to any symptoms. From the time we actually knew it was TCC and not an UTI, it was only 3 weeks before she had a stroke. The last week of her life, she basically had quit eating and we were just maintaining pain medications at that point. She was still able to get up and go outside and not having any accidents in the house.  I did find that when Sadie got where she did not want to eat, foods that smelled good appealed to her and they needed to be warm, not hot or cold.  I also put her meds in cream cheese which made them easier to give.  Prayers for both of you and just take each day as it was the last one.  MinnieMo Fri, 07 Sep 2012 00:00:00 GMT That is good news, prayers for all those still dealing with this horrible disease and prayers for all of us dealing with the loss of our beloved companions.  I miss Sadie every day.  MinnieMo Fri, 07 Sep 2012 00:00:00 GMT These last few days have my head spinning!  Thank you to all who have posted and sent prayers and good thoughts!  Bailey, thank god, seems to doing a bit better.  The dr believes it is a mild acute attack of pancreatitis!  Ultrasound was done today and kidneys came back good.  Also could be another UTI which I don't believe, because she just got done with 6 weeks of antibiotics two weeks ago.  Another issue going on now is that she had fallen off the bed onto her back after all this started and she now has some neck pain, as if this other stuff weren't enough! Again, thanks to all and I will update later.  Karin Baileysmom97 Thu, 06 Sep 2012 00:00:00 GMT Karin, I hope things get better for Bailey but it sounds like her and Chloe (and us) are in for some bad days ahead. Chloe has lost 5 lbs. in the last month. She weighed 35 in Jan. when dx and has lost down to 27. I think the prednisone is helping a little with her eating but I'm still concerned about the pee getting out. He said even a small clot could block her up. Please post and let us know how things go tomorrow. Will be praying for you both. Susan Chloebeaglemom Thu, 06 Sep 2012 00:00:00 GMT Hi MinnieMo, Did I ever write after the death of Sadie?  I am so sorry to hear about your loss.  You had so little time to prepare yourself for Sadie's loss.  I can understand how you would cry daily-- such a loss.  Please know that you are in my thoughts and prayers.  I feel like making a little memorial for the wonderful and loved dogs whom I have met thru their tremendous human companions through this site.  Maybe I'll make a donation to Purdue and list all their names.  Hopefully someday they will find a cure for canine TCC tyhat may help humans also.  Love,  Nita Nita Thu, 06 Sep 2012 00:00:00 GMT I'm so sorry to hear about the loss of Sadie and that so many other of our loved ones have this horrible cancer. Tiny Tot started out in January with UTIs that just wouldn't go away. Antibiotics worked for a bit, but then the infection would come back, and it got so bad that, on urinalysis they couldn't see any cells but bacteria. The vet changed his antibiotic to Clavamox, and we kept him on it for about 8 weeks straight. Everytime we stopped a 2 week cycle, he would get blood in his urine again. It's been about a month now since we've seen blood & have taken him off antibiotics for now, although I have a feeling he'll be going back on soon. It was early June when she finally told us that it was cancer, and he probably has months to a year. We are not doing any surgery or treatments that would affect his quality of life. That is the most important thing to us, keeping him the happy little dog he is for as long as possible, and then keeping him comfortable. The doctor prescribed Piroxicam, which he takes every other day, and I've started preparing food for him. I still give him dry food, but have changed him to Blue (less grains). I've been preparing ground meats with veggies (spinach or peas & carrots). I make a bunch in crockpots & store in small containers in the freezer. He's only 13 lbs so he doesn't eat a lot, and it's easier for me. I also gave him yogurt when he was on antibiotics to replace the good bacteria.  He's still a happy little dog, with a very good appetite, and at his last check-up, the vet told us the tumor was smaller. TinysMom Thu, 06 Sep 2012 00:00:00 GMT Hi MinnieMo. I was so surprised to receive a reply.  And of course I'm really sorry to hear about Sadie, your Lab -- it's a lovely name and I'll have a look for her pic around here.  How old was she?  I don't know whether to say it may have been better that she passed on more quickly instead of having to suffer too long.  I  hope that eventually you'll only have the wonderful memories about her and not the painful ones.  Labs, if I remember correctly, love swimming and pools.  I had a couple friends when I was young who had labs and they were always in the swimming pools with us! Pets really are akin to family members, aren't they?  I've lost two human family members to cancer (lung and leukemia), and it seemed odd that when I heard today about the TCC I thought immediately of what I was and wasn't able to do for my human family to make their lives comfortable.  I'll keep in mind what you said about keeping my dog comfortable and eating. She certainly hasn't lost her appetite yet. :) Must go.  Take care and thank you again! Cathtalk Thu, 06 Sep 2012 00:00:00 GMT I am so sorry to hear about your sweet dog. I had a Scottie once, loved him very much.  We just lost our Lab, Sadie, 3 weeks ago to TCC, I wish I could offer some miracle suggestions but sadly this is the scorge of the dog cancers.  As to feeding, stay about from carbs, but at the same time you want your dog to keep eating.  As to the cause, TTC is breed specific to Scotties and Westies and a few others. In other dogs and also in Scotties, yes herbicides and pesticides in lawns are a concern. There is a wealth of info on TCC on the Internet, simply google TCC in dog, especially studies done at Purdue Vet as they specialize in TCC in dogs. Also you can google cancer diets for dogs and find lots of info.  I cry daily for my Sadie. :(  We lost Sadie so quickly there are things I would have done differently such as focus more on just keeping her comfortable and not so much trying to cure something that there is no cure for.  Many dogs survive for months, Sadie was certainly the exception in that from the time we found out for sure she had cancer, she lasted only 3 weeks. Our oncologists feels that she had it much longer and it simply did not manifest any symptoms until it had really spread. Her tumor was in the vaginal vault and not her bladder so that might have allowed her to not have symptoms until close to the end.  Prayers for both you and your beloved companion. MinnieMo Wed, 05 Sep 2012 00:00:00 GMT Hi everyone.  I just found this forum and have been reading some of your posts -- there are so many I hardly know where to begin.  Chloe, Bailley, and so many others. I'm so glad I found somewhere to come and read and share.  I hope your dogs are able to live comfortably and have good quality of life for as long as possible.  It sounds like such an awful, terminal disease. I too just learned my 6 1/2 year old scottie dog probably has TCC -- the vet saw something suspicious in the ultrasound today and the antibiotics have only had limited benefits.  I'm anguished by the developments.  I wonder if it was exposure to lawn chemicals as down here in So. Florida there is so much of that done -- I've always tried to keep her away from them whenver I see signs on laws. Now I"m trying to figure out what all I'll be able to do for her -- she's practically like my child as I'm single, never married, have no children.   The vet is about to start her on some stronger drugs (proxima), and we hope it will help slow the tumor's growth.  I'm investigating what kind of dietary changes we can make for her. I'll be sure to follow your postings on this thread,  I posted to another one here too.  Cathy/Megan's 2nd mom Cathtalk Wed, 05 Sep 2012 00:00:00 GMT Dear Karin, Not Bailey, too! Karin, I feel like crying. You, like Susan, feel like such a friend after all the posts and all the care and love that you have given to Bailey.  I also feel so very angry at this terrible disease!!! Maybe someday there will be a cure. Please keep us posted.  It must have been such a shock to you to have Bailey go from feeling good to being so ill all of a sudden. Wow-- please take care of yourself and know that I'll be thinking about you and Bailey and also praying for you guys.  Love you,   Nita Nita Wed, 05 Sep 2012 00:00:00 GMT Dear Susan, I'm so very sorry to hear about Chloe.  I feel like I know you through your posts and I know that you have taken excellent care of Chloe, but this horrible disease always takes our beloved dogs in the end.  Someday I will be in the same position with my sweet Rocky and, like you, I don't know how I'll make it through.  Although nothing can be done to stop the inevitable, please know that I and others who have posted here (even the people whose companion animals have passed away and, understandably, are no longer posting) hold you in our thoughts with love.  Rocky's vet, too, has promised to come to our home when the time eventually comes, and knowing that is reassuring.  Take care of yourself during this very stressful time and know that you are in my thoughts and prayers. Love,  Anita Nita Wed, 05 Sep 2012 00:00:00 GMT Well, as if this cancer weren't enough, Bailey also, we think, is having kidney issues.  It was as if someone flipped a switch...she went from running around in the park in the afternoon to critical care in the hospital that night.  Right now she's on 24hr fluids and will probably have an ultrasound tomorrow, but she hasn't even been able to stand up the last day.  She only weighed 11.6 pounds and now lost one pound in about 2 weeks!  Curiously, Bailey also has a heart murmur but it was diagnosed at the beginning of her TCC.  Susan, I'm with you, I just don't know how I'm going to get through this.  Everything was looking good, we were getting ready to put her the Neoplasene and now this.  It really stinks.  Karin Baileysmom97 Wed, 05 Sep 2012 00:00:00 GMT Took Chloe to the oncologist yesterday. She had been straining and peeing that had more blood in it. He did blood work and an ultrasound. One of her kidneys had already been shut off from the tumor. The other one was functioning but her levels were elevated. The tumor had enlarged and bad progressed down her urethra as far as they could see. Also had a heart murmur that she hadn't had before. Sent her home with prednisone and pain meds. May not last much longer. I just don't want her to be in pain. She is still drinking good but not eating much. Just don't know how I'll make it through this. I asked the Dr. if he would come to my house when the time came and be said he would. Susan, Chloe's mom Chloebeaglemom Wed, 05 Sep 2012 00:00:00 GMT On Aug 10, 2012 6:41 PM Baileysmom97 wrote: First, I would like to send my best wishes for Chloe and hope she gets better. Bailey had an ultrasound yesterday which showed the cancer is still progessing throughout the bladder but has not made it into the urethra yet which is good.  Her two lymph nodes were a bit enlarged but hopefully this is just from the infection.  Her BUN is way up but her creatinine is stable so the doctor is stopping the Meloxicam.  She's got ten more days of Amoxicillin and then hopefully we can start the Neoplasene.  The good part is Bailey is still running around like nothing's going on...the hard part is waiting to get her on the Neo.  The doctor just doesn't want to irritate the bladder further if the infection is not cleared up.  I put Bailey back on the green tea extract and will also up her pro-biotics.  I've been reading that the pro-biotics seem to help with the general well-being and energy levels.  There were also results posted elsewhere on cancer compass regarding a human trial of green tea extract with leukemia patients and they experienced some positive results.  Who knows what really works...I think it's a matter of trying different things and see what works best for your situation. Sallie, if you read this, if you could let us know if Shelby ever had any bladder infections while she was on the neo I could maybe pass that on to my doctor.  She hasn't been able to connect yet with Dr. Kathy, but was going to keep trying.    Yes, Shelby did have some bladder infections during treatment.  Dr. Kathy just put her on an antibiotic and it cleared up.  She didn't seem hesitant to continue treatment with the neo and she never had a problem taking the antibiotic with the neo.  Also Shelby was on the greed yogurt everyday and that might have helped keep the infections down.  She liked it and it can't hurt.  I would ask the dr to go ahead and start the treatment.  At least talk to Dr. Kathy about it.  She can give more insight than me!!  But let me know if you have any other questions.  I'm glad to help. Sallie Shelbysmom2 Tue, 14 Aug 2012 00:00:00 GMT Debbie and Peaches-  A mom knows when her baby's time is coming. How great that you kept Peaches healthy for so long. It is NEVER easy to let them go. Please know that those of us who have had to make that very difficult decision of when to let our babies go are with you in spirit. Our babies will be waiting for Peaches at Rainbow Bridge and we continue to be here to support you during your grieving process. Be good to yourself these days as you are to Peaches. Love and prayers-  Copper's Mom CoppersMom Mon, 13 Aug 2012 00:00:00 GMT Hi Everyone,  This is Peaches mom, Debbie.  I have not posted on here since the end of May.  It just started to get very hard to talk about.  Peaches was diagnosed 2 years and 3 months ago, and at that time was given only 6-12 months, so she is one of the lucky (actually, I am the lucky one!!!).  Her last ultrasound showed that her tumor is now taking up almost all of her bladder, so I know we don't have too much longer.  She has been battling infection after infection.  She gets urine cultures every 3 weeks now and has been on all kinds of antibiotics.  I know I will need to make a decision soon which will probably be the hardest decision I will make.  I just wanted to see if anyone else was at this stage in this horrible disease..... Debbie MyPeaches Mon, 13 Aug 2012 00:00:00 GMT Hi Everyone,  This is Peaches mom, Debbie.  I have not posted on here since the end of May.  It just started to get very hard to talk about.  Peaches was diagnosed 2 years and 3 months ago, and at that time was given only 6-12 months, so she is one of the lucky (actually, I am the lucky one!!!).  Her last ultrasound showed that her tumor is now taking up almost all of her bladder, so I know we don't have too much longer.  She has been battling infection after infection.  She gets urine cultures every 3 weeks now and has been on all kinds of antibiotics.  I know I will need to make a decision soon which will probably be the hardest decision I will make.  I just wanted to see if anyone else was at this stage in this horrible disease..... Debbie MyPeaches Mon, 13 Aug 2012 00:00:00 GMT First, I would like to send my best wishes for Chloe and hope she gets better. Bailey had an ultrasound yesterday which showed the cancer is still progessing throughout the bladder but has not made it into the urethra yet which is good.  Her two lymph nodes were a bit enlarged but hopefully this is just from the infection.  Her BUN is way up but her creatinine is stable so the doctor is stopping the Meloxicam.  She's got ten more days of Amoxicillin and then hopefully we can start the Neoplasene.  The good part is Bailey is still running around like nothing's going on...the hard part is waiting to get her on the Neo.  The doctor just doesn't want to irritate the bladder further if the infection is not cleared up.  I put Bailey back on the green tea extract and will also up her pro-biotics.  I've been reading that the pro-biotics seem to help with the general well-being and energy levels.  There were also results posted elsewhere on cancer compass regarding a human trial of green tea extract with leukemia patients and they experienced some positive results.  Who knows what really works...I think it's a matter of trying different things and see what works best for your situation. Sallie, if you read this, if you could let us know if Shelby ever had any bladder infections while she was on the neo I could maybe pass that on to my doctor.  She hasn't been able to connect yet with Dr. Kathy, but was going to keep trying.     Baileysmom97 Fri, 10 Aug 2012 00:00:00 GMT Susan I'm so sorry for what you're going through.  Chloe sounds like a special girl.  I wish so badly than none of our babies have to go through this.  I will say a prayer for you both.  It's not an easy road to walk but you are doing everything right.  Just keep letting her know you love her. Sallie (Shelby's mom) Shelbysmom2 Fri, 10 Aug 2012 00:00:00 GMT On Aug 05, 2012 11:51 PM Chloebeaglemom wrote: Chloe has not had chemo for about 2 months. She's had some stomach problems, (not eating very much) and currently has a really bad bladder infection. She has become incontinent and cannot control when she pees. I've had to buy diapers for her because she was laying in a mess all the time. I had to give up on all the supplements I was giving her. I'm just lucky to get her to take a few bites of all the foods I have cooked. We had to stop the meloxicam too because the Dr. thought that could be causing part of her stomach problems. She will finish her antibiotics ( dailey shots) Wednesday and then I think we are doing another ultrasound. Really, I don't know why. Seems like we're at the point of no return. The chemo kept it stable for a long time. I just don't see her getting well enough to start the chemo again. She is still drinking water and enjoys snuggling and gets excited when family members come home. We found out she had the TCC on Jan. 2nd, after 3 months of different antibiotics. Until recently, you would not have known anything was wrong with her unless you saw her trying to pee. I remember reading others posts when their dogs were at this point in their journey, not believing Chloe would be here one day. This is a horrible disease. So sorry for the ones that have passed and the many yet to come. May we all have the courage to face the end with our furry little babies. Prayers for you all! Susan, Chloe's momAntibiotic is not working. Still has an infection, will find out tomorrow which antibiotic it is sensitive to. Found knot an her shoulder tonight, seems to be tender. Will show the Dr. tomorrow. Blew up the air mattress and me and her are snuggling in the floor together. Will keep you posted on how things go from here. Susan & Chloe Chloebeaglemom Fri, 10 Aug 2012 00:00:00 GMT Chloe has not had chemo for about 2 months. She's had some stomach problems, (not eating very much) and currently has a really bad bladder infection. She has become incontinent and cannot control when she pees. I've had to buy diapers for her because she was laying in a mess all the time. I had to give up on all the supplements I was giving her. I'm just lucky to get her to take a few bites of all the foods I have cooked. We had to stop the meloxicam too because the Dr. thought that could be causing part of her stomach problems. She will finish her antibiotics ( dailey shots) Wednesday and then I think we are doing another ultrasound. Really, I don't know why. Seems like we're at the point of no return. The chemo kept it stable for a long time. I just don't see her getting well enough to start the chemo again. She is still drinking water and enjoys snuggling and gets excited when family members come home. We found out she had the TCC on Jan. 2nd, after 3 months of different antibiotics. Until recently, you would not have known anything was wrong with her unless you saw her trying to pee. I remember reading others posts when their dogs were at this point in their journey, not believing Chloe would be here one day. This is a horrible disease. So sorry for the ones that have passed and the many yet to come. May we all have the courage to face the end with our furry little babies. Prayers for you all! Susan, Chloe's mom Chloebeaglemom Sun, 05 Aug 2012 00:00:00 GMT Our 7.5 year old black lab was diagnosed this past week. We have to decide on Monday what to do. Also in doing the tests we found she has arthritis, so with the discomfort from the tumor in her vaginal vault, and the hip pain, she is not getting around very well.  She was fine a week ago, except for the frequent attempts to urinate, we have been going to the Vet for a month thinking it was a UTI.  The lawn pesticide situation just makes it even worse.  I have taken her off all grains except some rice and feeding her meats, vegetables and fruits.  Google Graviola and you will find it online. our oncologist was not so sure about using it.  MinnieMo Sun, 29 Jul 2012 00:00:00 GMT So sorry to hear your news, but you will find a great source of info here about treatment options and people's experiences. I also chose not to go the chemo route. After a lot of online research and talking with a few vets, I chose oral neoplasene as a treatment. It hasn't made my dog sick at all and the cancer seems to be shrinking. I really recommend looking into it. Good luck with whatever path you choose. SienasMom Thu, 26 Jul 2012 00:00:00 GMT Just to give you a list of supps my Maltese x with a bladder tumor is on: Vascustatin, Beta Glucan, DHA Omega 3, K9Immunity & K9 Transfer, Digestive enzymes & a Glutathione accelerator. Plus  a raw meat diet with cancer fighting vegetables. There is a lot of help out there, you just have to start researching. I started with Cancer help for dogs onGoogle. My boy should have passed a month ago, but he's still powering on. Good luck. Deb tryeverything Thu, 26 Jul 2012 00:00:00 GMT Don't worry, I did that same thing a few times, it's irritating! So sorry that you got this bad news about Tiny Tot. I'm still getting email updates when new posts appear here and I can't help but read them even though my girl is now gone. I miss her so. amberye Thu, 26 Jul 2012 00:00:00 GMT Sorry. I really didn't mean for it to post twice. The post message button was acting strangely & when it didn't post after a bit, I tried again. Don't know how to delete one of them. TinysMom Thu, 26 Jul 2012 00:00:00 GMT Our sweet, loving little Min Pin, Tiny Tot, has recently been diagnosed with bladder cancer. We found him in our back yard 16 months ago. We turned him in so he could be reunited with his family, but nobody claimed him so we adopted him. He was 7 years old when we adopted him. He's been such a joy to have around & he's my son's first pet. As with so many others, he was being treated for a UTI that never seemed to go away. Before he'd be off antibiotics for a week, he'd have blood in his urine again. I'd already thought about the possibility of some sort of cancer, and at our next vet visit, our vet mentioned the possibility as well. She said his bladder wall was really thick. At his last visit, he seemed to be doing a little better, but there's a mass in his bladder. I was at work, and she broke the news to my husband & son that she's pretty sure it's cancer. She then called me at work to explain to me what she had told them. I've read about the first 70 pages of posts in this discussion. I'm working on changing him to more home-cooked food, spring water rather than tap water, and supplementing his home-cooked meals with Senior Blue dry food. I picked up his Piroxicam tonight. He's starting out on 2mg every other day. We are going to try to keep him as comfortable as possible for as long as he has left (which we hope is a long time), but we're not going to do any invasive testing or chemo. He seems to be a little uncomfortable at times. He sometimes will stop & lick himself, which is something he's never done since we've had him. It's like there's something bothering him in there & he wants to fix it. He still gets excited for his treats, but doesn't always eat them. He still eats his meals just fine, and I'm really lucky that, so far, I'm able to just mix his pills in with his food. We're so saddened by this news & it's terrible to think there are so many other pet families going through this same terrible thing. TinysMom Thu, 26 Jul 2012 00:00:00 GMT Our sweet, loving little Min Pin, Tiny Tot, has recently been diagnosed with bladder cancer. We found him in our back yard 16 months ago. We turned him in so he could be reunited with his family, but nobody claimed him so we adopted him. He was 7 years old when we adopted him. He's been such a joy to have around & he's my son's first pet. As with so many others, he was being treated for a UTI that never seemed to go away. Before he'd be off antibiotics for a week, he'd have blood in his urine again. I'd already thought about the possibility of some sort of cancer, and at our next vet visit, our vet mentioned the possibility as well. She said his bladder wall was really thick. At his last visit, he seemed to be doing a little better, but there's a mass in his bladder. I was at work, and she broke the news to my husband & son that she's pretty sure it's cancer. She then called me at work to explain to me what she had told them. I've read about the first 70 pages of posts in this discussion. I'm working on changing him to more home-cooked food, spring water rather than tap water, and supplementing his home-cooked meals with Senior Blue dry food. I picked up his Piroxicam tonight. He's starting out on 2mg every other day. We are going to try to keep him as comfortable as possible for as long as he has left (which we hope is a long time), but we're not going to do any invasive testing or chemo. He seems to be a little uncomfortable at times. He sometimes will stop & lick himself, which is something he's never done since we've had him. It's like there's something bothering him in there & he wants to fix it. He still gets excited for his treats, but doesn't always eat them. He still eats his meals just fine, and I'm really lucky that, so far, I'm able to just mix his pills in with his food. We're so saddened by this news & it's terrible to think there are so many other pet families going through this same terrible thing. TinysMom Thu, 26 Jul 2012 00:00:00 GMT Siena is 50 lbs and she currently gets 1.5 cc twice a day (mixed into her food). We started at 1 cc twice a day and worked up slowly to a higher dosage. I believe that she is at the max dosage for her weight.  I don't give her much else, because I don't want to overload her system with chemicals and potentially counteract the effects of the neo. Its important that there not be any anti-inflammatory medicines, for example, like Deramaxx. I do give her 1000 mg of fish oil a day and a multi-vitamin. I also changed her diet to make sure there are no grains, carbs or sugars, which means I cook her meat (chicken and beef) and veggies with a low-glycemic index. I think this has been important as well, as carbs and sugars feed the tumor's growth. I hope Bailey's infection clears up soon - three weeks is a long time! (Siena has successfully taken antibiotics while on neo, BTW. She had a liver infection several weeks back.) Best of luck. SienasMom Wed, 25 Jul 2012 00:00:00 GMT Siena's mom--I would be curious to know how much Siena weighs and what dose she's getting for the neoplasene.  Also if you could post whatever else she's taking in conjunction with the neoplasene.  Thanks Baileysmom97 Tue, 24 Jul 2012 00:00:00 GMT Thanks for thinking of us...we are waiting for the bladder infection to be cleared up before the doctor starts the neo.  It's so hard to wait...I really want to get this going!  Bailey's been on antibiotics now for 3 weeks so I'm trying to get her in to see the doctor.  Hopefully within the next week or so. Glad to hear Siena is doing well.  All in all it sounds like it's going very well.  I know it seems to take some time, but atleast if it shrinks it little by little that's awesome!  Keep us posted as to how she's doing. Baileysmom97 Mon, 23 Jul 2012 00:00:00 GMT Just thought I'd post a quick update that the neoplasene seems to be keeping Siena's tumor in check. You all know the frustrations of inexact measurements from ultrasounds, so its hard to know exactly how the tumor has changed. Nonetheless, after four months of treatment, the tumor appears to shrink slightly each month.The neo certainly isn't fast working, but I think its been very effective overall. She's in good health and hasn't had any side effects from the medicine. She is losing a little weight, but I think that's because I haven't figured out the right amount of homemade food to give her. Kibble was so much easier - I look forward to the day we get this tumor gone and she can go back to eating regular dog food again! Bailey's mom, have you been able to start on it yet? I was glad to hear someone else on the board was going to give it a try.  SienasMom Sat, 21 Jul 2012 00:00:00 GMT Hi Winseley's Mom, I am so sorry about your loss of Winsley. Chica and I are fighting.....for all of the pups that this awful disease has claimed.  We want to "thumb our nose" and "flip a dewclaw" to TCC.....to let it know that WE (yes, each and every one of us) all fought like the dickens and all who are left will continue to fight. Please remember all the good times with Winsley...she lived to make you happy and that's the way she would want you to be...even now that she is gone. ChicasMom, Lynn ChicasMom Wed, 04 Jul 2012 00:00:00 GMT Chris, I am so sorry to hear about Otis.  We're on the road and I just checked my email. Please know that you indeed did everything in your power to keep Otis as comfortable as you could and give him more time with you. NO REGRET'S, WHAT IF'S, I COULD HAVE'S/SHOULD HAVE'S!  You did it all and it was for your love of him.  He did not want more than your love....and he got it. ChicasMom, Lynn ChicasMom Wed, 04 Jul 2012 00:00:00 GMT Thanks for the kind words everyone....I'll keep and touch, and I wish only the best for you and you dogs... Take Care, Chris cgallo02 Tue, 03 Jul 2012 00:00:00 GMT Chris I am so sorry to hear about Otis.  You are in our thoughts and prayers.  Kim (Penelope's mom) penelopesmom Tue, 03 Jul 2012 00:00:00 GMT Chris I am so sorry to hear about Otis.  You are in our thoughts and prayers.  Kim (Penelope's mom) penelopesmom Tue, 03 Jul 2012 00:00:00 GMT It is indeed very sad to hear of Winsley and Otis passing away.  As Nita said, it's something the rest of us know we will have to deal with at some point. On a separate note, Bailey's specialist has agreed to oversee her taking the Neoplasene, although she thinks we have to get rid of the uti first.  The cancer has progressed to the trigone area so I feel that we need to get this going since all the things have stopped working.   Baileysmom97 Mon, 02 Jul 2012 00:00:00 GMT Chris, I'm so sorry to hear about Otis!!  {{{ Hugs }}} MomToBella Mon, 02 Jul 2012 00:00:00 GMT On Jul 01, 2012 10:28 PM cgallo02 wrote: Hi all..thought I'd let you know I lost my Otis today...the past few weeks he had not been doing well at all...he was down to a dribble and in alot of pain. I had the vet come on Thurs, but he seemed to be a little better that morning-I thought that maybe the prednisone, which he just started on Mon was kicking in, and I'd give him a little more time...I also looked into doing the stent...almost did it yesterday, but if at all, would have just bought him a few more months (unless it was the bladder tumor causing the obstruction, and then it would have done nothing)-and not happy ones-a stent would not shrink his bladder tumor or prostate, and this poor boy was in pain-not walking right, constantly panting and starting to cry...not able to jump off of couch or furniture-the urine just dribbling out of him at all times where he was constantly laying in urine...He was at a point where he had suffered enough. I thank you all for the information and support during this most difficult time; it has just meant everything... Chris       Chris , I am so very sorry to read that Otis is gone.  I have followed your posts, and feel like I know you and Otis.  The love for each other was obvious, and you certainly did all you could for him.  Please know that I'll be thinking about you, as will all of us on this site. Like all others on this site that have to euthanize their dogs, you put Otis above your own desire to have him with you, giving him a final gift.  You and Otis will certainly be in my thoughts and prayers.   Take care of yourself dduring this difficult time. Love,  Nita Nita Mon, 02 Jul 2012 00:00:00 GMT Having just been through this yourself, you sure do know how I feel...he was my best friend, and such a special guy. Otis would have loved Amber, as he loved everybody!! I'm sure they're getting acquainted, and Grandma (my Mom) is going to take good care of them-along with all the others !! Thanks so much Claire!! Hope the pain is easing for you. Love Chris cgallo02 Mon, 02 Jul 2012 00:00:00 GMT Gosh, I am so so sorry Chris. I don't even have anything good to say, just that Otis knew you loved him and that he loved you with all his houndy heart. Do you think Otis would have liked Amber? Do you think they're up there somewhere sniffing noses? Sending lots of love your way tonight. Claire amberye Mon, 02 Jul 2012 00:00:00 GMT Hi all..thought I'd let you know I lost my Otis today...the past few weeks he had not been doing well at all...he was down to a dribble and in alot of pain. I had the vet come on Thurs, but he seemed to be a little better that morning-I thought that maybe the prednisone, which he just started on Mon was kicking in, and I'd give him a little more time...I also looked into doing the stent...almost did it yesterday, but if at all, would have just bought him a few more months (unless it was the bladder tumor causing the obstruction, and then it would have done nothing)-and not happy ones-a stent would not shrink his bladder tumor or prostate, and this poor boy was in pain-not walking right, constantly panting and starting to cry...not able to jump off of couch or furniture-the urine just dribbling out of him at all times where he was constantly laying in urine...He was at a point where he had suffered enough. I thank you all for the information and support during this most difficult time; it has just meant everything... Chris        cgallo02 Sun, 01 Jul 2012 00:00:00 GMT On Jun 28, 2012 7:17 PM Wdog47 wrote: Hi all, I didn't spend much time on here, as I couldn't bear (sp?) to come on.  Yesterday Winsley woke up and could barely walk.  It came out of nowhere.  I lifted her into the car and she just looked at me and I knew.  I knew! OMG, not now- I drove her down to the beach and held her.  She wouldn't even get out of the car.  This man (angel) came out of nowhere and sat with us for 1/2 an hour and then just started praying.  I sobbed and sobbed.  I met my husband at the vet and the Dr. came out and checked her.  He said it was probably her spleen (she was very tired and lethargic and tummy distended).  We picked up our sons and they said goodbye.  At 12:30 she died peacefully in my arms.  I keep seeing her everywhere I turn.  I think she is behind me.  I am so devastated.  What will I do without my baby?  Where is she? how is she? I am somewhat relieved that she is not in pain and anxioius, but i still want her to be here.  Please keep fighting.  I am so tired of cancer.  I am so sad.  I am so sad.  Hi, I am so sad to hear about Winsley's passing.  I can't imagine what you are going through right now.  I know that someday I will have to face this with my soul dog Rocky, and I'm sure that the questions in my mind will be identical to yours.  What a difficult thing to go through.  Please take care of yourself, try to eat healthy food and pamper yourself as much as possible as you go through the mourning process.  Also know that those of us with dogs facing cancer will be thinking of you.  I wish there would be something I could do to help ease your sadness, but please know that our thoughts and prayers are with you. Love, Nita Nita Sun, 01 Jul 2012 00:00:00 GMT Hi Susan, thanks for thinking of me! That sounds about like how Amber reacted to the carboplatin, with the no appetite and she also wouldn't take anything with pills hidden in it. I had been rubbing them in butter and putting them down her throat and even if she wouldn't eat anything that day, she would always lick my buttery fingers. Good news that the tumor hasn't grown any! I still don't understand how Amber's grew so fast, it seems out of the norm compared with other's stories here. We miss her like crazy. She was all we ever talked about, my husband and I, sad huh? On a hike: look at how beautiful she is running! At home: look at how pretty Amber is on the couch! On facebook: just look at my beautiful dog running in the hills and sleeping on the couch! Is she straining to poop because of enlarged lymph nodes? Poor girl. She sounds like a sweetie pie. I sure miss Amber's love, she was the most affectionate dog. Our other dog is just not as lovey dovey. He's a good boy though and we love him. We have been looking at Vizsla breeders lately, even though I said NO MORE DOGS! I lied. We are sad without Vizsla energy in the house. Well, best of luck to miss Chloe. How are everyone else's dogs doing? Otis? amberye Sun, 01 Jul 2012 00:00:00 GMT On Jun 19, 2012 3:10 PM Chloebeaglemom wrote: Claire, so very sorry for you. I can't believe it happened so fast. I know you did all you could for Amber. I know we are all facing this one day. So sorry yours came so soon. Will be thinking of you and please remember all of us who are still fighting this dreadful disease. Chloe's Mom SusanClaire, Chloe is still doing fairly well. I think it was about 8 weeks ago she had her first round of the carboplatin. She lost her appetite, lost a couple of pounds and was kinda yucky for about 5 weeks. We did another ultrasound at 6 weeks and the tumor had not grown any. We decided to do another round of carboplatin but at 1/4 less dosage. She has done well with it. No sickness and still eating well. In 2 weeks we will do another ultrasound to see how things look. She still seems to be straining very hard to pee and poop. She is still on meloxicam. I had been doing all kinds of supplements, but when she quit eating, I couldn't sneek any pills into anything. She would just smell stuff and walk away. So the meloxicam is the only thing I'm giving her now. Funny how I can hide it in a small marshmallow and throw her a few at a time, she don't take time to smell, just swallows them whole. I know any day could be the last, from your experience. It makes me sick to know what I have to eventually face. Right now we are enjoying snuggling on the sofa or on our bed. She enjoys that and being rubbed. If I stop, that paw comes up and scratches my hand as if to say don't stop. I think of you often and hope things are getting a little better for you. Susan, Chloe's mom Chloebeaglemom Sun, 01 Jul 2012 00:00:00 GMT On Jun 28, 2012 5:25 PM Shelbysmom2 wrote: Maybe you could contact the people at Buck Mountain and they could tell you. I hope it works out for you. Keep us posted.I actually did call Buck Mountain...I spoke with Pat, a very lovely person.  They don't seem to have a list of who they send their product to.  I did contact Dr. Kathy and she's willing to work with my vet.  She actually knows a doctor very close to me, however, I'm not sure I would want to start with someone new to my case.  I'm still hoping that my specialist in Philly will agree to try the Neo.  The one thing that I am amazed by is how all of these doctors and staff have responded.  They have been so willing to provide me with information and have either emailed or called me back within a short time.  There are truly some wonderful people. If I cannot convince my specialist to go this route, then I will probably use the local vet.  I feel the time is definitely now before this continues spreading. Baileysmom97 Fri, 29 Jun 2012 00:00:00 GMT Hi Karin,  I'm so sorry to hear about Bailey. We used black salve on our beautiful bulldog Gnocchi - and it did help her. You can read about it here: www.mumsnothavingchemo.com/2011/09/the-black-salv-ation/ I don't know a holistic vet in the New York area but I have heard of a fantastic one in Florida called Dr Lynn Peck. Perhaps you could contact her? She might know someone in your area. In the meantime, does anyone know of a holistic vet in London? Laura LondonLaura Fri, 29 Jun 2012 00:00:00 GMT Hi all, I didn't spend much time on here, as I couldn't bear (sp?) to come on.  Yesterday Winsley woke up and could barely walk.  It came out of nowhere.  I lifted her into the car and she just looked at me and I knew.  I knew! OMG, not now- I drove her down to the beach and held her.  She wouldn't even get out of the car.  This man (angel) came out of nowhere and sat with us for 1/2 an hour and then just started praying.  I sobbed and sobbed.  I met my husband at the vet and the Dr. came out and checked her.  He said it was probably her spleen (she was very tired and lethargic and tummy distended).  We picked up our sons and they said goodbye.  At 12:30 she died peacefully in my arms.  I keep seeing her everywhere I turn.  I think she is behind me.  I am so devastated.  What will I do without my baby?  Where is she? how is she? I am somewhat relieved that she is not in pain and anxioius, but i still want her to be here.  Please keep fighting.  I am so tired of cancer.  I am so sad.  I am so sad.  Wdog47 Thu, 28 Jun 2012 00:00:00 GMT Maybe you could contact the people at Buck Mountain and they could tell you. I hope it works out for you. Keep us posted. Shelbysmom2 Thu, 28 Jun 2012 00:00:00 GMT Well, we went for an ultrasound on Monday and there seems to be some progression of the TCC to the trigone area.  She also has another UTI and will go on a round of amoxicillin.  Not what I was hoping for. Anyone know of a holistic vet in the New Jersey/New York/Pennsylvania area who has used Neoplasene? Karin Baileysmom97 Thu, 28 Jun 2012 00:00:00 GMT Thanks so much, Sallie! I do have another dog, Rye. He was pretty worried the first few days and was VERY happy to see us when we got home from work but he's settling back in it seems. It's weird since he was the older of my two dogs at 11 years old and he is pretty much in perfect health. He and Amber have always been best friends and I know he wonders where she went. amberye Wed, 20 Jun 2012 00:00:00 GMT Claire I'm so saddened to hear about your sweet Amber. Her picture was so beautiful and it sounds like she had a beautiful spirit to match. I know exactly how you feel having lost my Shelby just two weeks ago. It's going to be so hard not having her with you. But you have to focus on all the wonderful years you had together. Especially the happy times you shared. That is what I'm trying to do. I know you question if you did the right thing but it seems like her situation was pretty advanced and I know that you wouldnt want her to suffer. That helped me make my decision and even so I question it but Shelby just wouldn't eat and couldn't get up anymore. I also believe that it is our responsibility to make these difficult decisions because we have committed ourselves to the best care for them and they are counting on us. Even though that makes it even harder. She knew you loved her though and you stayed right with her showing her you loved her. That's a very loving thing to do. It has helped me that I have other dogs so the house is not so empty. I don't know if you do have other dogs but it does help. I will be thinking and praying for you. I know it almost unbearable but just keep trying. I'm hoping it will get easier too. Sallie (Shelby's mom) Shelbysmom2 Tue, 19 Jun 2012 00:00:00 GMT Thank you so much, Chloe's mom. I will not forget you all. I will probably end up checking back in with you guys more often than I thought I would. How is Chloe doing? amberye Tue, 19 Jun 2012 00:00:00 GMT Claire, so very sorry for you. I can't believe it happened so fast. I know you did all you could for Amber. I know we are all facing this one day. So sorry yours came so soon. Will be thinking of you and please remember all of us who are still fighting this dreadful disease. Chloe's Mom Susan Chloebeaglemom Tue, 19 Jun 2012 00:00:00 GMT Thank you all very much for your support. It was nice, even though short, having this place to come to for information and company. I can't believe it happened so fast, so many other dogs have had much longer it seems. I wish all of your dogs, and you, love and peace. Claire amberye Tue, 19 Jun 2012 00:00:00 GMT Dear Claire, I'm so sorry to hear that Amber is gone. I definitely know you did the right thing for her, even through it was so terribly hard for you.  I can't imagine the loss you are feeling right now, and I am so sad when I know that someday I will have to go through this with my own dog , Rocky.  Don't feel guilty for not staying with this site.  I probably will not stay on when something happens to Rocky since I'm pretty sure I'll find it too painful.   But please know that I will miss you and your entries, and you will remain in my thoughts and prayers as you go through the mourning process. Lots of love, Nita Nita Mon, 18 Jun 2012 00:00:00 GMT Claire, I am so sorry to hear about Amber. I know in my heart that you did all you could for Amber...and...I KNOW, without a shred of doubt, that Amber knew how much you loved her and would do everything to take care of her...even in the end. You made the right decision...it was made out of love for Amber.  One more day for yourself was not worth having Amber have one more day of not being able to pee or be in pain.  I know in your brain you know this, but, in your heart...well that's another story. Yes, life will not be the same.  You will remember the good times with her AND she would not want you to be sad forever.  She spent her lifetime doing her "job", keeping you safe, making you laugh and loving you without asking much in return...only your love. Again, I am so sorry. ChicasMom, Lynn ChicasMom Mon, 18 Jun 2012 00:00:00 GMT Claire, I'm so sorry to hear about Amber. It must be a terribly hard time for you, but how lucky you were to have all those good years together. I can tell from your posts that you are a wonderful dog owner and gave Amber lots of happy times. Take care of yourself and know that you have lots of understanding friends here. Hugs, jenn. SienasMom Mon, 18 Jun 2012 00:00:00 GMT Hi all, I know that I haven't known you long but I thought I'd let you all know that Amber is gone. I took her to visit my dad a few hours away from us on Friday. We had a wonderful little hike by the creek Friday morning. Amber seemed so normal and got to run like she loved to do. Then Saturday morning she was trying to pee much more often than she had been. I drove her home. When we got back to town I let her out of the car and she tried to pee but nothing was able to pass. I got my husband and we went to the vet. It was horrible. She tried to pee on their lawn, nothing, tried to pee in their lobby, nothing, in the exam room, nothing. She was whining. We talked about putting in a stent. My understanding of the situation a few months ago was that they could put in a urinary catheter first and then the stent but the doctor said she didn't think she would be able to pass a catheter into her bladder. So it was either do the stent or have her put to sleep. I made the choice based on the fact that her lymph nodes were very enlarged and she was having a harder and harder time pooping as well. The vet thought that the stent would not have given her that much more time and that it wouldn't have been quality time. It was the worst thing I have ever had to go through. My heart felt like it was shredded through the paper shredder. I don't know if I made the right decision or not. Now I feel that even one more day with her would have been better than this. I could hardly bare to leave her at the vet. I did stay while they put her to sleep. It was very fast and easy. They used an anesthetic first so she was very sedate when they used the actual euthenasia drug. She was my best friend, my baby, my everthing. I don't know what I will do without her. Life will not be the same. Anyway, I don't know how much I will stick around, I guess most people wouldn't keep talking about cancer after their dog had passed. So, thanks for the advice, for talking and I am so sorry that all of your dogs have to go through this horrible thing. Much love, Claire amberye Sun, 17 Jun 2012 00:00:00 GMT Hi Sienna's mom, They did do a V-BTA test--it came back negative. The doc said the tests were very unreliable and we couldn't trust it (which makes me wonder why exactly we did it...but we did!) :) SweetPeasMommy Fri, 15 Jun 2012 00:00:00 GMT Siena is a border collie, about 54 lbs. Much smaller than your sweet pea. (Such a cute picture you posted of her.) I don't see why it wouldn't be safe on a small dog. Just as with chemo, dosage is based on weight. I go to a regular vet at one of the large animal hospitals here in Utah. She's holistically trained, in addition to classical training. There's a search tool here, so you look in your area. http://ahvma.org/Widgets/FindVet.html SienasMom Fri, 15 Jun 2012 00:00:00 GMT Hi SweetPea's Mommy-- The doctors might be able to determine if it truly is TCC by obtaining a urine sample and then spinning it to try and separate out any TCC cells.  Bailey was originally supposed to have a cystoscope inserted via the urethra but she had an infection at that time so they couldn't do it.  After the infection cleared up, we went back and they were able to find the cells in the urine. As far as the neoplasene, it will usually be a holistic vet that would give it a shot.  Dr. Fox of buckmountainbotanicals.net is willing to speak with any veterinarians willing to try it. Baileysmom97 Fri, 15 Jun 2012 00:00:00 GMT Hi Sienna's mom, How big is Sienna? Do you think it would be okay on such a small dog? Also, did you have to go to a special vet? Thanks! SweetPeasMommy Fri, 15 Jun 2012 00:00:00 GMT I have heard the same thing, that as the bladder walls expand and contract depending on how full it is, the tumor will expand and contract too. To get as accurate a measurement as possible, I try to take Siena at the same time of day for each appointment and with a full bladder. I'm sorry to hear sweet pea is having such a tough reaction to the drugs. I followed in Shelby's pawprints and have Siena on neoplasene. The cancer is responding well to the treatment, that is to say that it is shrinking. In addition, she doesn't have any reactions to the medicine (no nausea, vomiting, etc). If you ever have any questions about it, let me know. I think its a really valid approach to treating this disease. SienasMom Fri, 15 Jun 2012 00:00:00 GMT Hi everyone, Thanks for the replies, both here and personally. A few asked about biopsy--because she is so small, there is not a catheter that is large enough to fit the device needed to extract the tumor, but small enough to fit in her. That's why we are having to rely solely on ultrasounds, and with the "seeding," I won't let the doctors remove a piece any other way. In any event, I think I was just looking for any excuse to believe she couldn't be inflicted with this horrible disease. Good news, her white blood cell count was great after chemo, but the bad news is that she started getting bloody diarehhea and vomit today, so we have to stop the piroxiciam for a bit. I am not sure if the vet will tell us to restart that, or switch to a different med after a week. It's gut-wrenching even to watch the side effects of these medications, but I know it is for the best. How is everyone else's baby doing? Sweet pea's mom SweetPeasMommy Fri, 15 Jun 2012 00:00:00 GMT I was told that because of differences of how full the bladder is, it is always difficult to compare from one ultrasound to the next.  This also applies to measuring the tumor. Baileysmom97 Thu, 14 Jun 2012 00:00:00 GMT Hi, Would people be willing to share/compare ultrasounds of their dog's bladder tumor?  The tumor in the second ultrasound looks totally different and appears to move depending on how they have photographed it, which leads me to believe (or hope) that it is just, in fact, a blood clot.  I don't know if I am just in denial though. If so, private reply me and I will send my email address and her ultrasound images.  Sweet Pea's Mommy SweetPeasMommy Wed, 13 Jun 2012 00:00:00 GMT Thank you Shelby's mom! And I meant to say yesterday what a beautiful girl Shelby was, her serious face reminds me of Amber a little. I have always been a "hippy girl" kind of person, using natural remedies for everything, eating very naturally, so I don't know why I've gone so much to the pharmaceutical drug side with Amber. I somehow feel that the natural cures are not going to work in this case but I am obviously wrong since Shelby was cured using a natural substance. amberye Tue, 12 Jun 2012 00:00:00 GMT To those who mentioned having diarrhea. There is a product you can buy on the Internet called Firm Up. It is all natural dehydrated pumpkin and apple. You mix it with water or I put it in yogurt for Shelby. When she first started on Neoplasene she had diarrhea but I started giving her this after each meal and no more problem. It's by Diggin something but you can find it on the Internet. I will always have some in my house with 3 dogs cause you never know when one will get sick. This stuff works great. Shelbysmom2 Mon, 11 Jun 2012 00:00:00 GMT Hi Claire! I would say pain from the tumor..which would get worse as the tumor gets bigger--the tumor pressing us against neighboring structures, nerves-can be real painful (I remember with my Mom)-That's why I was assuming that his tumor was probably getting bigger-unless he just felt sick from the chemo; he is better now-not great, but eating, drinking not hesitating when jumping on couch anymore-and it is up and down-a lot! I wish they could talk--he may say, "Why don't you leave me alone, you crazy woman?  "LOL...do you think the butter may give he diarrhea?? Well, back upstairs I go to check the chicken (chicken and rice tonight for the boys) Take Care!! cgallo02 Mon, 11 Jun 2012 00:00:00 GMT Chris, I know that panting can be a sign of pain, it would seem like that would be the cause. But pain from what? Amber hasn't done the panting but her eyes have had a "look" in them for a while now, just a "I don't feel 100% right" look. Amber has had diarrhea about every other day, we were on the sulfasalazine but switched to metronidazole two days ago. Amber also seems to go up and down quite frequently, running and playing like normal one day and then not eating or doing much of anything the next. I wondered if I was letting her run too much and it was causing pain, I don't know. Also, I just noticed on Saturday that she whines when I touch her hind end. I picked her up to put her on the exam table at work for her blood draw and she yelped. I did find that butter makes her want to eat! I started putting her pills in a little butter so they'd go down her throat easier and then she licks my fingers and then magically she will eat! Something about the butter stimulates her appetite? So hard to know, don't you wish they could talk to us? Best wishes to Otis. amberye Mon, 11 Jun 2012 00:00:00 GMT On Jun 11, 2012 2:19 AM Shelbysmom2 wrote: Thank you all for your kind words.  Shelby was so special to us as I know all yours are to you.  She was the most loving dog ever and it's left a terrible void in our life.  It is good though that we have 3 other dogs so we are still busy caring for them.  If the house was empty, it would be harder.  Thank you Sienna's mom for the thoughtful words.  I hope that Shelby has helped someone.  At least we can all share our experiences and gain from them.  Chris, Shelby would pant on the days I gave her Piroxicam.  Maybe that is the reason for Otis's panting?  Thank you all again.  It helps to know others support you during the worst days.Otis has had a panting issue for about a month-it's been much worse for the last 3 days...at first, I did blame it on the piroxicam, so i stopped it for about a week and saw no difference..I think the panting is from pain-the Oncologist says he pokes away at him on examination and Otis shows no distress, so he does not think it's from pain- The past 3 days it's been an incessant pant with a weird, scared look in his eyes with long naps in between episodes-also a hesitance to jump up on me or the couch, which he usually does with no problems-tramadol was not helping, and I stopped the Piroxicam 3 days ago (as I always do when he starts acting weird)-I did give it to him last night though in the hopes of providing relief..not sure if it worked-although he did settle down an go to sleep. He had diarrhea last pm and again this am-the vomitted this am (first time) and refused his rice...he went and laid down for 2 hours-then he got up, voided a nice big bloodless puddle-the kind he did before all this started, and was running around wagging his tail and begging for treats-I don't know what to think...it gets better as fast as it gets bad... I was thinking that the tumor was just getting bigger and causing him pain, but now I wonder if it isn't a reaction to the chemo (Mitoxantrone)-I thought we saw these side-effects in 3-5 days-this all started 9 days later...Well, we're going to get some blood work, an ultrasound and monitor him to see what's going on. cgallo02 Mon, 11 Jun 2012 00:00:00 GMT So sorry to hear about Shelby, but glad for you that the end was peaceful and that you have your three other dogs to keep you busy. To Sweet Pea's Mom, ring and take her to your vet. It is hard to say if it's from the chemo, I found that no dose ever had the same effect, sometimes Poppy was very crook, other times, she was absolutely fine. It's beginning to become clear that Poppy is starting on a downward decline.  After 3 months of great progress on piroxicam and finishing 5 rounds of chemo, the piroxicam affected her kidney function and the piroxicam stopped.  3 weeks later, the blood in her urine is back and she is beginning to strain without an infection being present.  It really has been a case of one step forward and two steps back.  Not sure what our next steps will be, time will tell I guess, but hope this information gives you a bit of an idea of what can happen. Best wishes and thoughts with everyone.  poppy06 Mon, 11 Jun 2012 00:00:00 GMT I don't mean to be insensitive to dear Shelby by posting this question, but i am very scared. BSweet Pea has refused to go up or down stairs today. We had chemo on Wed. Is this normal after chemo or could it already be spreading? SweetPeasMommy Mon, 11 Jun 2012 00:00:00 GMT What a beautiful pup Shelby was. Just know that you did everything you could for Shelby and really, Shelby did everything she could for you. That's what our dogs do--and did--and what they love to do most: to selflessly give us happiness in times of sadness, comfort in times of pain, companionship when we are lonely, and memories to live with forever. It sounds like Shelby did her job. I'll be thinking about you and your family and I know that, with time, things will get easier. "Grief is like the ocean; it comes on waves ebbing and flowing. Sometimes the water is calm, and sometimes it is overwhelming. All we can do is learn to swim." - Vicki Harrison SweetPeasMommy Mon, 11 Jun 2012 00:00:00 GMT Shelby was a beautiful soul both inside and out.  Thank you for sharing her picture. My avatar is of my fur baby Bella who left us almost one year ago.  I still miss her every day. I hope that you find peace in knowing that you did everything you could for her and that she had a happy life with you. MomToBella Mon, 11 Jun 2012 00:00:00 GMT I put a picture of Shelby as my profile picture so you can all see what a sweet old soul she was! Shelbysmom2 Mon, 11 Jun 2012 00:00:00 GMT Thank you all for your kind words.  Shelby was so special to us as I know all yours are to you.  She was the most loving dog ever and it's left a terrible void in our life.  It is good though that we have 3 other dogs so we are still busy caring for them.  If the house was empty, it would be harder.  Thank you Sienna's mom for the thoughtful words.  I hope that Shelby has helped someone.  At least we can all share our experiences and gain from them.  Chris, Shelby would pant on the days I gave her Piroxicam.  Maybe that is the reason for Otis's panting?  Thank you all again.  It helps to know others support you during the worst days. Shelbysmom2 Mon, 11 Jun 2012 00:00:00 GMT oh, I'm so sorry to hear this...please accept my condolences...but 14 is darn good-especially with battling this horrible disease..I felt blessed to have my Kelly until 12-a Golden-Yellow lab mix-blind and very brittle diabetic-until that age! Your input in regards to neoplastene will no doubt help somebody..maybe even me...so thanks for sharing..Dr. Dressler even has it in his book ( The Dog Cancer Survival Guide) Otis has been a panting mess for 3 days now-don't know what to think..being treated with vinblastine and mitroxatrone-was doing very well up until this point-darn, it's only been 2 months since diagnosis-I was not thinking I'd have to be contemplating putting him down so soon--my heart breaks for me, Otis, Shelby and every other dog and guardian facing this-and you now that you have to face the harsh reality.. Keeping you (and Ken) in my prayers...you were a terrific mom!! Chris cgallo02 Mon, 11 Jun 2012 00:00:00 GMT I'm so sorry to hear about Shelby. {{{{ Hugs }}}} MomToBella Sun, 10 Jun 2012 00:00:00 GMT Shelby's Mom and Ken, I am so sorry for your loss.  Shelby had a wonderful life, yes even the last year of her life was wonderful....she had you and Ken. She knew you both loved her and she trusted in you to do the best FOR her, and you did, right to the end. I know that you are hurting terribly but try to remember the good times, Shelby had 14 years.  That's pretty darn good for a golden/mix and it's all owed to the fact that you loved her and took very good care of her. Shelby's running with the rest of the pups over Rainbow Bridge....she's waiting for you....anticipating and recognizing your footfall....tail  wagging, tongue lolling....close your eyes....see her....she is very happy! God bless you both. ChicasMom, Lynn  ChicasMom Sun, 10 Jun 2012 00:00:00 GMT I am so so terribly sorry to hear about Shelby. The news brought tears to my eyes. It seems that so many that we lose on this board die from cancer, so its good to hear she reached a ripe old age. I can imagine she had many wonderful days dining on costco chickens and green beans. I have learned so much from you and what you have shared about her treatment. Siena is doing really well on the neoplasene. The tumor is shrinking and she hasn't had any side effects. Without your postings and encouragement, I don't know that I'd have done it. I am so glad I did. You and Shelby are making a difference in our lives and I can't thank you enough.  I hope you are doing okay in these tough times. My heart goes out to you. I wish I had the words to convey my true feelings of fondness and appreciation for you and Shelby. Jenn SienasMom Sun, 10 Jun 2012 00:00:00 GMT Hi Shelby's mom. I am so sorry that she is not in her physical body any more. That is a good long life for a golden girl! Claire amberye Sun, 10 Jun 2012 00:00:00 GMT Sorry to report to you all that Shelby left us on Friday.  It was time to say goodbye.  As you have probably read here on this board Shelby was treated with Neoplasene and actually expelled her bladder tumor back in January.  She did absolutely beautifully after that and an ultrasound about 8 weeks ago still showed no sign of a tumor. Unfortunately, Shelby's age of 14 is what finally caused us to make the decision.  Over the last 3 weeks or so Shelby started having trouble getting up and walking.  After reading the messages here that this cancer can sometimes move to the spine I was very concerned.  The vet took x-rays and said there was NO evidence of ANY cancer in her spinal area.  Just a lot of arthritis.  She put her on some anti-inflammatories and also we did laser and acupuncture that day.  About a week or so later she began to cry in the middle of the night.  Whimper really.  I think that she could not get up and it was frustrating her and also she was in some pain.  I took her to my regular vet on Memorial weekend and they also took more x-rays.  Again, no sign of anything but arthritis.  This time we got tramadol for the pain and we were hoping that she would be able to get up on the tramadol.  But it didn't turn out that way.  While the tramadol seemed to help her pain she still could not hardly get up on her own.  She began to urinate all over herself and lay in it until one of us would come and get her up.  All these months I've been worrying that she would stop being able to urinate and instead she was going all the time all over herself.  We continued to clean her and help her out.  She could walk but not well.  Then last Monday she stopped eating.  She just would not eat anything and believe me we tried everything.  She threw up a few times what looked like bile and she began to get weaker.  We spent a lot of precious time with her during the week.  Letting her sit outside and sitting beside her petting her.  Petting was always the thing she loved the most.  I layed on the kitchen floor with her on Thursday night and I know that she knew she was loved.  By Friday morning she was very weak and she told us that she was ready to go.  It was very peaceful.  We took her to the vet and she was very calm and didn't even get nervous.  She slipped silently away in mine and Ken's arms and the last thing she saw was that we loved her and that we thought she was precious.  It's the hardest thing to let a sweet, sweet dog go but I do know that her quality of life was not there anymore and I could not let her suffer. To those of you who have been following the Neoplasene story I do believe that if Shelby had been 8 or even younger that we would have bought her many years.  However, she was just too old to really get much extra time.  I'm not sorry we did it as she breezed through the treatment with no major side effects and also I know the vet is very high on the treatment because of Shelby.  I hoped she helped at least one other dog.  To be fair though, I will tell you that on Thursday she had blood in her urine.  Something she had never had before.  I asked the vet about it and if it could mean that her cancer was back but she attributed it to her not being able to empty properly and not being able to squat to pee.  She said theres no way the tumor could have come back when it was completely gone 8 weeks ago.  Still it does make me wonder and I'm posting it because it did happen and I only wish we knew why. My hope goes out to Sienna and any other dog on the Neoplasene that you have as much success as we did and maybe it really will buy you some time.  And for those who are trying chemo or whatever else I hope you all have great success and long and happy times with your beloved pets.  Our hearts are broken and we are in morning here but at least we had that precious soul for 14 years.  By the way, Shelby was a golden retriever mix if anyone is wondering.  Love and best wishes to all of you. Our fight is over but we pray the best for you as yours continues.   Shelbysmom2 Sun, 10 Jun 2012 00:00:00 GMT Hello and welcome Sweet Pea's mom! So sorry that you are here like the rest of us. Your vet sounds pretty much exactly the same as mine as far as treatments except Amber's first chemo was the mitoxantrone and her second one the carboplatin. She handled the mitoxantrone very well but the carboplatin made her pretty sick for almost a week. She is back to good again now though, eating well and running in the hills like she loves to do. Our next treatment with mitoxantrone again will be next week with a cbc tomorrow. Lots of luck to little miss Sweet Pea. Sending her love from afar. Chris, so glad you have insurance for Otis! I do not have it for myself or my dog. I am spending way more on her treatments than I probably should but I just couldn't decide not to do it. As far as laser treatment or other treatments I know that that is way out of my price range. Even though this dog is my best friend and means so much more to me than I could possibly describe I know that I have to draw the line somewhere. I hate to admit it. I am poor. I am lucky that I work for a vet clinic and can get some of her medications at a reduced cost, also her cbc tests every week are cheap at work! Talk to you later, goodnight! Claire amberye Sat, 09 Jun 2012 00:00:00 GMT Hi, I hope I'm replying correctly--I'm new here. I'm the mommy of a 10 year old Yorkie who was diagnosed on June 6th. I've reread a lot of the posts here and let me first extend my condolences to everyone who is struggling with this disease and seeing their babies go through this. Second, let me offer my congratulations for not letting this disease get the best of us, or our pups. A lot of times, treatments are a matter of trial and error and it is so helpful to see what others have tried and what has worked (and what hasn't), keeping in mind that every baby is different. I noticed that Shelby's mom had considerable success with Neoplasene. I've tried to reread the some 2,400 posts but it is hard to catch up. Was Shelby given neoplasene with any other treatments? Is it safe to start Sweet Pea on an oral dose of neoplasene while she is on Prioxiciam and receiving carboplatin treatments? Just to possibly help others, I received this letter from my vet about TCC and Sweet Pea, it's informative: "Sweet Pea presented today for recheck evaluation of the abnormalities in her urinary bladder.  She was doing well at home over the last few weeks with no problems, although she has had increased frequency of urination and return of the blood in her urine over the last few days. Examination today showed no evidence of pain or masses on abdominal palpation, no abnormal urination, and Sweet Pea's weight was 7.48 lbs. A recheck ultrasound was performed today which showed a large mass within the center (lumen) of her urinary bladder, arising from the dorsal wall of her bladder.  We discussed that based upon her history of urinary abnormalities and the appearance of the mass in her urinary bladder, along with her being a small breed and female dog, we believe that she most likely has a cancer called transitional cell carcinoma (TCC).  This is the most common tumor found in the urinary bladder. Generally, TCC occurs in older dogs and it tends to occur in females more frequently than in males. It can occur more commonly in certain breeds of dogs such as Scotties, Westies, Beagles, other terriers, and other small breed dogs.  This cancer will cause dogs to have bloody urine, urine dribbling, straining to urinate, and frequent urination. Secondary urinary tract infections are common with TCC.  These tumors have the potential to metastasize, usually to nearby lymph nodes and the lungs, rarely to other abdominal organs.  Chest x-rays and abdominal ultrasound are recommended in order to determine how far this cancer has spread. We discussed that Sweet Pea's ultrasound shows that her nearby lymph nodes are normal. Treatments options for this cancer are unfortunately very limited due to the often late stage of disease at the time of diagnosis and the prognosis is poor.  This tumor usually occurs in the trigone region of the bladder and often invades important nearby structures such as the ureters and urethra.  This makes this tumor impossible to resect with surgery if it occurs in this location.  Sweet Pea's tumor is arising very near the trigone of her bladder and the insertion sites of her ureters, and she is not a candidate for surgical excision of the tumor. Since these tumors are aggressive and potentially metastatic, treatment typically centers around palliation (controlling the growth and clinical signs) with anti-inflammatory drugs (Piroxicam) and/or chemotherapy, and/or radiation therapy.  We can see approximately 30-40% of dogs have a response to the anti-inflammatory medication, chemotherapy, or the combination of the two. The non-steroidal, anti-inflammatory medications such as Piroxicam have been shown to be effective at killing cancer cells in TCC and this drug also decreases inflammation around the tumor. Improvement in clinical signs can be seen in 40-60% of patients with this medication alone.  These medications are given daily at home and are generally well-tolerated. Side effects may include gastrointestinal signs such as vomiting, diarrhea, and rarely GI ulceration.  Long-term use can cause some kidney damage, so bloodwork is recommended about every 6 months for monitoring of the kidneys.  This medication cannot be given with other anti-inflammatory drugs such as prednisone, Rimadyl, Deramaxx, or aspirin. Chemotherapy has also been used with TCC, with improvement seen in approximately 30-40% of patients.  We have found equal responses with the chemotherapy agents carboplatin and mitoxantrone.  Chemotherapy in dogs is generally well-tolerated.  Since we often cannot cure this cancer, our goal is to slow or stabilize the growth of the tumor and maintain a good quality of life.  We give just enough chemotherapy to slow the progression of the cancer with acceptable side effects.  The chemotherapy is given as an intravenous injection approximately every 3 weeks.  Both of the chemotherapy options are fairly well-tolerated with some nausea, vomiting, or decreased appetite that may be seen 2-3 days after receiving the injection.  If the GI signs occur, they are usually minimal and resolve in 24-48 hours. We often send home an anti-nausea medication to administer if any of these side effects occur.  If the signs are severe or prolonged (seen in less than 10% of dogs), we may recommend hospitalization with supportive care for 24-48 hours.  Chemotherapy can also decrease the white blood cell count, which could increase susceptibility to infections. We check bloodwork (CBC) one week after the treatment to ensure that the white blood cell count is adequate.  If the white blood cell count is significantly decreased, we may recommend a prophylactic antibiotic to help prevent infection.   It can be difficult to determine how well the treatments are working for TCC.  We use clinical signs (improvement in incontinence, decrease in blood in urine, decreased frequency or straining of urination) to monitor response and we also can recheck the tumors with an ultrasound periodically to see if there is improvement.  Urethral stenting and/or radiation therapy can also be given to help relieve some of the effects from the tumor (pain, straining, obstruction) if they occur. We obtained baseline bloodwork for Sweet Pea today and no abnormalities were noted.  We elected to start therapy for Sweet Pea with piroxicam and carboplatin chemotherapy.  She received her first injection of carboplatin chemotherapy today.  This chemotherapy is fairly well-tolerated with some nausea, vomiting, or decreased appetite that may be seen 3-5 days after receiving the injection.  If the GI signs occur, they are usually minimal and resolve in 24-48 hours. Anti-nausea or anti-diarrhea medication can be prescribed as needed for any side effects. This chemotherapy drug can also decrease the white blood cell count, which could increase susceptibility to infections. We will recheck bloodwork (CBC) one week after the treatment to ensure that the white blood cell count is adequate.  If the white blood cell count is significantly decreased, we may recommend a prophylactic antibiotic to help prevent infection.  Rarely, this drug can cause irritation of the skin if inadvertently given outside of the blood vessel, so let us know if there is any redness, irritation, excessive licking, swelling, or discharge in the area of the chemotherapy injection.  Please contact us with any concerns. Please administer her medications as prescribed below. Please call or email with any questions or concerns. Sweet Pea should return to us in 1 week for CBC, and 3 weeks for recheck exam, CBC, and next dose of Carboplatin. Medications: Piroxicam 3mg tablets: Give 1/2 tablet by mouth once daily with food." Belly rubs and wet kisses to all! Sweet Pea's Mommy SweetPeasMommy Sat, 09 Jun 2012 00:00:00 GMT Hi, I hope I'm replying correctly--I'm new here. I'm the mommy of a 10 year old Yorkie who was diagnosed on June 6th. I've reread a lot of the posts here and let me first extend my condolences to everyone who is struggling with this and seeing their babies go through this. Second, let me offer my congratulations for not letting this disease get the best of us, or our pups. A lot of times, treatments are a matter of trial and error and it is so helpful to see what others have tried and what has worked (and what hasn't), keeping in mind that every baby is different. I noticed that Shelby's mom had considerable success with Neoplasene. I've tried to reread the some 2,400 posts but it is hard to catch up. Was Shelby given neoplasene with any other treatments? Is it safe to start Sweet Pea on an oral dose of neoplasene while she is on Prioxiciam and receiving carboplatin treatments? Just to possibly help others, I received this letter from my vet about TCC and Sweet Pea, it's informative: "Sweet Pea presented today for recheck evaluation of the abnormalities in her urinary bladder.  She was doing well at home over the last few weeks with no problems, although she has had increased frequency of urination and return of the blood in her urine over the last few days. Examination today showed no evidence of pain or masses on abdominal palpation, no abnormal urination, and Sweet Pea's weight was 7.48 lbs. A recheck ultrasound was performed today which showed a large mass within the center (lumen) of her urinary bladder, arising from the dorsal wall of her bladder.  We discussed that based upon her history of urinary abnormalities and the appearance of the mass in her urinary bladder, along with her being a small breed and female dog, we believe that she most likely has a cancer called transitional cell carcinoma (TCC).  This is the most common tumor found in the urinary bladder. Generally, TCC occurs in older dogs and it tends to occur in females more frequently than in males. It can occur more commonly in certain breeds of dogs such as Scotties, Westies, Beagles, other terriers, and other small breed dogs.  This cancer will cause dogs to have bloody urine, urine dribbling, straining to urinate, and frequent urination. Secondary urinary tract infections are common with TCC.  These tumors have the potential to metastasize, usually to nearby lymph nodes and the lungs, rarely to other abdominal organs.  Chest x-rays and abdominal ultrasound are recommended in order to determine how far this cancer has spread. We discussed that Sweet Pea's ultrasound shows that her nearby lymph nodes are normal. Treatments options for this cancer are unfortunately very limited due to the often late stage of disease at the time of diagnosis and the prognosis is poor.  This tumor usually occurs in the trigone region of the bladder and often invades important nearby structures such as the ureters and urethra.  This makes this tumor impossible to resect with surgery if it occurs in this location.  Sweet Pea's tumor is arising very near the trigone of her bladder and the insertion sites of her ureters, and she is not a candidate for surgical excision of the tumor. Since these tumors are aggressive and potentially metastatic, treatment typically centers around palliation (controlling the growth and clinical signs) with anti-inflammatory drugs (Piroxicam) and/or chemotherapy, and/or radiation therapy.  We can see approximately 30-40% of dogs have a response to the anti-inflammatory medication, chemotherapy, or the combination of the two. The non-steroidal, anti-inflammatory medications such as Piroxicam have been shown to be effective at killing cancer cells in TCC and this drug also decreases inflammation around the tumor. Improvement in clinical signs can be seen in 40-60% of patients with this medication alone.  These medications are given daily at home and are generally well-tolerated. Side effects may include gastrointestinal signs such as vomiting, diarrhea, and rarely GI ulceration.  Long-term use can cause some kidney damage, so bloodwork is recommended about every 6 months for monitoring of the kidneys.  This medication cannot be given with other anti-inflammatory drugs such as prednisone, Rimadyl, Deramaxx, or aspirin. Chemotherapy has also been used with TCC, with improvement seen in approximately 30-40% of patients.  We have found equal responses with the chemotherapy agents carboplatin and mitoxantrone.  Chemotherapy in dogs is generally well-tolerated.  Since we often cannot cure this cancer, our goal is to slow or stabilize the growth of the tumor and maintain a good quality of life.  We give just enough chemotherapy to slow the progression of the cancer with acceptable side effects.  The chemotherapy is given as an intravenous injection approximately every 3 weeks.  Both of the chemotherapy options are fairly well-tolerated with some nausea, vomiting, or decreased appetite that may be seen 2-3 days after receiving the injection.  If the GI signs occur, they are usually minimal and resolve in 24-48 hours. We often send home an anti-nausea medication to administer if any of these side effects occur.  If the signs are severe or prolonged (seen in less than 10% of dogs), we may recommend hospitalization with supportive care for 24-48 hours.  Chemotherapy can also decrease the white blood cell count, which could increase susceptibility to infections. We check bloodwork (CBC) one week after the treatment to ensure that the white blood cell count is adequate.  If the white blood cell count is significantly decreased, we may recommend a prophylactic antibiotic to help prevent infection.   It can be difficult to determine how well the treatments are working for TCC.  We use clinical signs (improvement in incontinence, decrease in blood in urine, decreased frequency or straining of urination) to monitor response and we also can recheck the tumors with an ultrasound periodically to see if there is improvement.  Urethral stenting and/or radiation therapy can also be given to help relieve some of the effects from the tumor (pain, straining, obstruction) if they occur. We obtained baseline bloodwork for Sweet Pea today and no abnormalities were noted.  We elected to start therapy for Sweet Pea with piroxicam and carboplatin chemotherapy.  She received her first injection of carboplatin chemotherapy today.  This chemotherapy is fairly well-tolerated with some nausea, vomiting, or decreased appetite that may be seen 3-5 days after receiving the injection.  If the GI signs occur, they are usually minimal and resolve in 24-48 hours. Anti-nausea or anti-diarrhea medication can be prescribed as needed for any side effects. This chemotherapy drug can also decrease the white blood cell count, which could increase susceptibility to infections. We will recheck bloodwork (CBC) one week after the treatment to ensure that the white blood cell count is adequate.  If the white blood cell count is significantly decreased, we may recommend a prophylactic antibiotic to help prevent infection.  Rarely, this drug can cause irritation of the skin if inadvertently given outside of the blood vessel, so let us know if there is any redness, irritation, excessive licking, swelling, or discharge in the area of the chemotherapy injection.  Please contact us with any concerns. Please administer her medications as prescribed below. Please call or email with any questions or concerns. Sweet Pea should return to us in 1 week for CBC, and 3 weeks for recheck exam, CBC, and next dose of Carboplatin. Medications: Piroxicam 3mg tablets: Give 1/2 tablet by mouth once daily with food." Belly runs and wet kisses to all! Sweet Pea's Mommy SweetPeasMommy Sat, 09 Jun 2012 00:00:00 GMT Hi Karin! I know-I saw Dr. Cerf as well-geez, all of these procedures are expensive-even the stent is not so cheap (I've gotten prices of $2500-$3000) Otis has insurance, but you know- they don't cover a whole lot-I'm fighting with them now over the chemo treatments (and he does has a cancer rider)-I've already spent a bundle, just as everyone here has, and I watch my dog pant all day and watch my hair turn gray! I sort of feel that it comes back no matter what you do ( I'm even looking into CyberKnife-another bargain LOL) That's why it's just one day at a time and see how it goes-it would be so lovely if the chemo shrunk it down to nothing and we could just go on with out lives, but that's not going to happen-when the time comes it may just make sense to do the stent-we'll see how he does! Chris cgallo02 Fri, 08 Jun 2012 00:00:00 GMT On Jun 07, 2012 11:14 PM cgallo02 wrote: Hi Claire! Sooo glad she is better-it's so up and down-Otis has been panting allll day...just been miserable-but I don't see any blood in the urine today, there's been no accidents or dribbling-this is so weird; and it changes that fast! I looked in my lab book, and I don't think the BUN and CR are included in CBC-that does not really thrill me, but good to know so I don't assume a symptom could not be kidney-related. I've noticed alot of dogs on this forum that do the carbo have a hard time with it...and it doesn't necessarily mean that it's working-maybe we could justify the suffering if it was at least working- Otis's tumor is in the trigone of the bladder-2 x 1 cm with uretheral and prostate involvement-he voids a decent stream-I see a lot of people posting that their dogs just dribble-this is not the case here- yet. If the chemo can knock it down awhile, we'll be ok, but I will eventually be faced with obstruction and what to do about it. The question is-do I just solve that pending problem (with a stent) or go for it with laser ablation and clean out the urethera and debulk the tumor? The laser procedure seems risky, so I'm a little scared. Uretheral stents seem to work great to open the urethera, but I wonder if they close up over time-and does that even matter given the dog's poor prognosis?  The laser seems to be the best chance for anything semi-long term....I'm also looking into radiation (IMRT or Cyberknife) but I'm not sure that will address the urethera-it would work on the bladder and prostate though...oh, and how am I going to pay for all of this??LOL Jimminy Crickets I better win that lottery!! Happy she's better! Chris  Hi Chris-- I had gone to see Dr. Cerf about a year ago to discuss the laser ablation.  First, it was very expensive, about $8k and there was no guarantee that the tumor wouldn't come back.  He told me of several cases where owners would go back and have it done again.  One dog's tumor even came back just after a month, so it really depends on how aggressive the cancer is.  If money factors into the equation, it probably makes more sense to go with a stent.  Karin Baileysmom97 Fri, 08 Jun 2012 00:00:00 GMT Hi Claire! Sooo glad she is better-it's so up and down-Otis has been panting allll day...just been miserable-but I don't see any blood in the urine today, there's been no accidents or dribbling-this is so weird; and it changes that fast! I looked in my lab book, and I don't think the BUN and CR are included in CBC-that does not really thrill me, but good to know so I don't assume a symptom could not be kidney-related. I've noticed alot of dogs on this forum that do the carbo have a hard time with it...and it doesn't necessarily mean that it's working-maybe we could justify the suffering if it was at least working- Otis's tumor is in the trigone of the bladder-2 x 1 cm with uretheral and prostate involvement-he voids a decent stream-I see a lot of people posting that their dogs just dribble-this is not the case here- yet. If the chemo can knock it down awhile, we'll be ok, but I will eventually be faced with obstruction and what to do about it. The question is-do I just solve that pending problem (with a stent) or go for it with laser ablation and clean out the urethera and debulk the tumor? The laser procedure seems risky, so I'm a little scared. Uretheral stents seem to work great to open the urethera, but I wonder if they close up over time-and does that even matter given the dog's poor prognosis?  The laser seems to be the best chance for anything semi-long term....I'm also looking into radiation (IMRT or Cyberknife) but I'm not sure that will address the urethera-it would work on the bladder and prostate though...oh, and how am I going to pay for all of this??LOL Jimminy Crickets I better win that lottery!! Happy she's better! Chris   cgallo02 Thu, 07 Jun 2012 00:00:00 GMT Thank you Chris! So good to be able to go through all this with someone familiar to what is going on. Amber was peeing in the house at night too til we got her the doggy door. She did have an infection at the time it all started but I think it is just the cancer growing, and the inflamed cells in there saying I have to pee NOW! Every time we have done a UA on her there is blood in it. Not visible when she pees, just under the microscope. And when we did the scope (I work at a vet clinic so I was able to be there and help with it) you could see the blood floating around in there. What do you think you will do if and when his urethra is blocked? We at first thought we would for sure do the stent but now I'm thinking that by the time she needs a stent she may have other issues and that it wouldn't be of that much use. But then again if it happened tomorrow that she could not pee I would still do it since she is still pretty healthy otherwise. Remind me again where Otis' cancer is growing? Amber's is right in the urethra. Her bladder is still clear of disease as far as I know. Amber is eating really well again. I've been cooking for her and she loves it. She even ate some kibble that my other dog left in his bowl this morning which is the first kibble she's eaten in weeks. Her diarrhea is gone too so that is good. I am not sure about the BUN or CR, I thought those were included in the cbc but I could be wrong. I have not heard whether Deramaxx is easier on the kidneys or not, I know it can have the same affects as Peroxicam and that I do have to watch out for kidney damage just that it is easier on the stomach. We have had a good couple of days. She seemed pretty normal yesterday so I took the dogs on a hike by the river where she goes insane leaping logs, jumping in the river, looking for birds, it was hard to imagine that she is sick. I also thought I noticed her trying to pee less but it could be my imagination. I am nervous for the next chemo but it will be the mitoxantrone that did not bother her as much so hopefully that is still the case. I really hope Otis keeps responding well to the chemo and does start to feel more normal, longer. That's good that it makes him feel better afterward! It would make me feel that I was justified in going through with the chemo. Thanks for talking and yeah, this stinks. Claire amberye Thu, 07 Jun 2012 00:00:00 GMT Hi Claire! Otis has been peeing sporadically in the house since all this started....I correlate the accidents to infections, because he seems to have accidents when he has a UTI-I thought he had another one, but the culture came back negative (I was going to say, so much for the cran-tabs-LOL) a lot of blood in the urine too-the vet says it could be the cells dying off from the chemo (I guess that'a a good thing?) So, he's a little off again-his pattern, unlike yours, is that he's great the first 5 days or so after chemo, then it acts up again..I'm worried for the day his urethera gets blocked, because that is decision time... Glad Amber is eating, and hopefully her diarrhea has stopped-you know, contrary to what I thought, my oncologist is only checking blood counts on Otis day of chemo and at 7 days-I don't believe that includes a BUN and CR (kidney function)I guess they only check that periodically (not weekly) I guess we should be on the look-out for signs of kidney failure (God forbid!) especially on the Piroxicam (is Deramaxx better for this?) because they are not monitoring that as closely (maybe that happens over time?) Hope you and Amber had a better day--this really just stinks and my heart goes out to every dog and care-taker going through this. Chris cgallo02 Thu, 07 Jun 2012 00:00:00 GMT On Jun 06, 2012 1:58 AM amberye wrote: Thank you, Sue. This is just horrible! It would be one thing to grow old gracefully and have to be put to sleep because they couldn't get up anymore, or something like that, but this is just so wrong :( So you feel that the biopsy caused it to spread? Why don't the vets know enough about this? I asked my vet before we did the biopsy and he assured me that it would only cause "seeding" if he were to get the sample by using a needle through her abdomen rather than through the scope in her urethra. I still think it may have caused spread. Before the biopsy her lymph nodes were normal. Or I guess I just want to blame someone for this, maybe it would have happened no matter what was done. I'd like to hear from people who think their dogs have tcc but haven't had a biopsy. I'd be curious to know how long their dog lived and what changes they noticed. We had to get Amber a doggy door because she was peeing overnight on the floor. Goodnight. It's highly unlikely that the cystoscope biopsy caused the cancer to spread.  The only way that could happen is if the bladder were punctured.  The difficulty with this type of cancer is that most of the time there are really no syptoms that there is anything wrong.  I only found out with mine because she was peeing  alot more often and drinking more water so we started looking into why this was going on.  Most people find out way too late because of the lack of symptons.  As this cancer progresses, the first place it usually spreads to are the lymph nodes and then either the lungs or bones. I would try to find a vet willing to do the Neoplasene.  My dog was diagnosed about 1 1/2 years ago and the tumor had been fairly stable.  It just started expanding the last few months.  I did chemo with her, that was awful.  Surgery was done because it looked like they could remove the tumor, but when they got in there it was much too close to the ureters.  Two stents were put in from the kidneys to the bladder and she's doing ok.  I have her on some holistic stuff (salvestrols) to try and kill the cancer.  We'll probably go for an ultrasound at the end of this month to see if there has been any effect.  If not, I will be pushing my doctor to try the Neoplasene.  She was willing to research it and speak with Dr. Fox, however, she has not come to a determination yet. Baileysmom97 Thu, 07 Jun 2012 00:00:00 GMT Thank you, Sue. This is just horrible! It would be one thing to grow old gracefully and have to be put to sleep because they couldn't get up anymore, or something like that, but this is just so wrong :( So you feel that the biopsy caused it to spread? Why don't the vets know enough about this? I asked my vet before we did the biopsy and he assured me that it would only cause "seeding" if he were to get the sample by using a needle through her abdomen rather than through the scope in her urethra. I still think it may have caused spread. Before the biopsy her lymph nodes were normal. Or I guess I just want to blame someone for this, maybe it would have happened no matter what was done. I'd like to hear from people who think their dogs have tcc but haven't had a biopsy. I'd be curious to know how long their dog lived and what changes they noticed. We had to get Amber a doggy door because she was peeing overnight on the floor. Goodnight. amberye Wed, 06 Jun 2012 00:00:00 GMT Thanks Claire - Dazz is similiar to Amber as she had her last "good" run at thh end of March - and started noticing some hesitancy jumping mid April - she was able to compete one last time before I even knew what was going on but I could tell was not herself (stutter stepping and slower).  I would have never had the biopsy if the vet even THOUGHT they were lymph nodes enlarged!  Looking back, perhaps a 2nd opinion or ultrasound would have helped.  Dazz had UTI symptoms around that time, but also could not do stairs well or jump even onto the low couch.  I noticed alot of extra peeing the past two days two and had her on antibiotics and may just give her again - first time she has had accidents in the house since this started. Hoping you and Amber have some good quality time and lots of it! Sue   suebon Tue, 05 Jun 2012 00:00:00 GMT Hi Sue, I am so sorry to read about Dazzle. I read a few of your other posts and see that she was an agility dog. My 8 year old Vizsla, Amber was also an agility dog with her MACH run in March of this year being the very last run before we found out the official diagnosis of tcc. I also can't believe that such a healthy active dog could develop this horrible disease. I feel like I've given her all the best foods all her life, all the exercise and fun she could get and now she's got cancer, it just doesn't make sense to me. Amber also has enlarged sublumbar lymph nodes. Also, I read that you felt she went downhill after the surgery, I also felt like Amber went downhill after we did a cystoscope and biopsy and was worried that the biopsy had caused cancer cells to spread. I don't think I would do it again if I had it to do over. She was perfectly normal other than peeing a lot before the biopsy and seems a little less like herself every day. She is eating again finally though so I am happy for now. Lots of love for Thursday. Claire amberye Tue, 05 Jun 2012 00:00:00 GMT I did do a series of chemo on one of my shelties that had lymphoma and she did not tolerate much of it at all.  I guess every dog is different! I think I have made my decision to say good bye to Dazzle.  She continues to go downhill, I increased her tramadol and also got gabapention (sp) and started adding that on Saturday.  I am still in shock this dog was showing no signs of anything being wrong 2 months ago.  She is on a multitude of holistic and homeopathic things, and nothing is having any effect and each day is a little worse.  She gets up and down ok, goes out to go potty, but there is no tail wag, no barking at me, no toy grabbing, and did not even get up to come out last night do the barn chores with the rest of the dogs.  She eats three hearty meals a day.  I wish I could base it on that, but she is one tough dog, and I think for me to see pain in her means she is in pain, and knowing it had already spread to her lymph nodes has made me give up hope of it getting better or stabilizing.  She keeps wanting to lay on her back or press it up against things which makes me think it is in her spine now, and keeping her here is more for me than for her. I am having my friend who is a vet come to the house on Thursday and will spend the morning with her.  This has been so very hard to watch and so hard that i could not do more for her.  Sue & Dazz     suebon Mon, 04 Jun 2012 00:00:00 GMT Hi Chris, She is on deramaxx rather than piroxicam, but yeah, it could be from that. I haven't given it to her on the two days she hasn't eaten to try to avoid more stomach upset. Yeah, it was just yesterday morning before we went in for the treatment that she wouldn't eat, that was the first time, but also she seemed pretty normal, after chemo she is super wiped out and did I mention the diarrhea? DIARRHEA! My poor baby dog. Yes, we did a cbc last week and then directly before yesterday's chemo and they said it looked good to go. I sure hope she bounces back soon! I'm about ready to go try feeding her again, she just took a long nap with me on the couch. I'm glad Otis is doing better with the cranberry capsules! And I sure am glad he is tolerating the chemo so well! Thanks for your concern! Claire amberye Fri, 01 Jun 2012 00:00:00 GMT Hi Claire! Sorry to hear that Amber is off today-Otis had his second treatment Wed (Mitoxantrone this time)-we're pretty good so far---he did not "lick his dinner bowl clean"-(first time in 9 years that's happened) but he is eating... What's so hard when they're off is that it could be for a number of different reasons..if she was not eating before the chemo, it may not be that..it could be the Piroxicam, maybe a UTI brewing, or just the cancer...I'm assuming that your vet is checking blood counts before chemo to make sure renal function is ok..? I've read on numerous posts of this happening to dogs and then they bounce back...and I'm preparing myself for when it happens to me- Please keep us updated...I'm concerned. Chris ps-thanks for the cran tip-he doesn't like them, but he hasn't had a recurrence ..yet.. cgallo02 Fri, 01 Jun 2012 00:00:00 GMT Thank you all for your replies, it's good to read about what others have done. I'm glad you wrote that about supplements, Rio's mom, because I keep adding more and more and maybe that's some of why she doesn't want to eat much anymore, it probably tastes funky. amberye Fri, 01 Jun 2012 00:00:00 GMT Thank you Bailey's mom! Our vet wants to keep doing the chemo, but the next treatment will be with the mitoxantrone again, I'm not sure if I will do it or not, she didn't react poorly to that one at all but I sure don't want to make this worse.  I don't understand all the people who say that dogs respond well to chemo, this is not WELL! Thanks again. amberye Fri, 01 Jun 2012 00:00:00 GMT On Jun 01, 2012 2:43 AM amberye wrote: This morning Amber wouldn't eat breakfast and then at 10:00 we went in for her second chemo treatment, using carboplatin this time. Up until this morning she had eaten every meal. Now she won't eat dinner and is very low energy. I am planning on bringing her to work with me ( I work for a vet clinic) tomorrow if she is still not eating by the morning. For those of you whose dogs have had loss of appetite what has the vet done for you? She is already on metaclopramide for upset stomach/lack of appetite. Mid day she did eat a little bit of cooked beef heart but now she won't even eat that. Not the roasted turkey, or canned Evo either, nothing. Do you feel it is the cancer itself causing this or the chemo or both? ClaireHi Claire-- My dog Bailey received Carboplatin back in March and she had a terrible time with it.  She weighed about 12 pounds at the first injection and lost almost a whole pound over the course of a few weeks.  Even with anti-nausea meds and injection, it didn't help to stimulate her appetite.  I did not continue the chemo and it didn't stop the tumor from growing.  Bailey wasn't back to normal until 4 weeks after the injection.  My guess is that it would be the chemo. I tried all her favorite foods but it was really a struggle to get her to eat.  Just try to keep offering the stuff she likes and hopefully her appetite will return. Baileysmom97 Fri, 01 Jun 2012 00:00:00 GMT Claire, In Rio's case, the vet told me that when a dog's kidneys aren't functioning properly, his/her stomach feels upset.  We also tried the stomach medication you used, but Rio eventually refused it, even when I crushed it and mixed it in ice cream.  I hope this is a temporary situation for your pet.  I feel your concern, and I was desperate with worry.  The holistic vet stressed to me that food was more important than any supplements, so when Rio got fussy about eating, I had to stick with salmon, chicken, buffalo -- whatever he would eat.  My heart goes out to you.  Hang in there. Iloverio Fri, 01 Jun 2012 00:00:00 GMT On Jun 01, 2012 2:43 AM amberye wrote: This morning Amber wouldn't eat breakfast and then at 10:00 we went in for her second chemo treatment, using carboplatin this time. Up until this morning she had eaten every meal. Now she won't eat dinner and is very low energy. I am planning on bringing her to work with me ( I work for a vet clinic) tomorrow if she is still not eating by the morning. For those of you whose dogs have had loss of appetite what has the vet done for you? She is already on metaclopramide for upset stomach/lack of appetite. Mid day she did eat a little bit of cooked beef heart but now she won't even eat that. Not the roasted turkey, or canned Evo either, nothing. Do you feel it is the cancer itself causing this or the chemo or both? ClaireI decided not to go with chemo because of those side effects. Instead I'm going the holistic approach. Definately no commercial food all home made, at the moment I'm using K9Immunity & K9Transfer to boost the immune system, fish oil & Ubuiqunol (coq10) I'm waiting for my order of Vascustatin to come & Aveúltra (for human cancer as well) My 12yrold maltese x has a bladder tumor, a few days ago he showed signs of straining to wee but since yesterday he's not too bad, hoping this concoction is kicking in. Oh! I give him a capsule of Artemix mixed in a little warm milk before bed on an empty stomach. This has changed my life completely. Deb tryeverything Fri, 01 Jun 2012 00:00:00 GMT This morning Amber wouldn't eat breakfast and then at 10:00 we went in for her second chemo treatment, using carboplatin this time. Up until this morning she had eaten every meal. Now she won't eat dinner and is very low energy. I am planning on bringing her to work with me ( I work for a vet clinic) tomorrow if she is still not eating by the morning. For those of you whose dogs have had loss of appetite what has the vet done for you? She is already on metaclopramide for upset stomach/lack of appetite. Mid day she did eat a little bit of cooked beef heart but now she won't even eat that. Not the roasted turkey, or canned Evo either, nothing. Do you feel it is the cancer itself causing this or the chemo or both? Claire amberye Fri, 01 Jun 2012 00:00:00 GMT My heart goes out to those of you who have been posting on here lately about the loss of their dogs. Its hard to read knowing that some day it will be me who is sharing some last memories. It is also wonderful to hear the sweet stories of what wonderful care you all provide your pups. The support on here from the TCC affected community is really phenomenal. Well, Siena's ultrasound showed that her tumor shrank from 30x12 mm to 27x10 mm in 7 weeks with the neoplasene treatment. She has been on 1 cc twice a day and we are going to increase that to 1.5 cc twice a day to see if we can improve the results. She's tolerating the medicine really well. The fight goes on... SienasMom Thu, 31 May 2012 00:00:00 GMT Dear Marianne, Thanks so much for sharing Rio's peaceful journey with us.  I read the message with tears in my eyes and can only hope that Rocky can have the same type of experience when the time comes.  It is appreciated and certainly shows strength that you plan on continuing to keep in touch with those of us on this site.  Please take care of yourself as you grieve Rio.  With love,  Nita Nita Thu, 31 May 2012 00:00:00 GMT On May 30, 2012 5:03 PM Iloverio wrote: Thank you so much Karin and to everyone else who reached out to me.  Rio had a very peaceful journey this morning.  We met the vet in the park by the river.  He pranced down to the water and took a big drink!  Of course, he could not pee afterwards, but that didn't stop him from trying.  He laid on his blanket under a large tree so we could say goodbye.  I got to tell him what a good dog he was, how he had filled a major void in my life, and how he could relax and go to sleep because his work here was done.  I told him he would soon be chasing deer and prairie dogs and squirrels.  I believe someday we will meet again in a better place.  I love all of you and intend to keep reading about you and your journies. MarianneMarianne, What a wonderful pet Mom, excellent care and an ending that SHOULD be written about. Rio was lucky to have chosen you! I am so sorry for your loss. ChicasMom, Lynn ChicasMom Wed, 30 May 2012 00:00:00 GMT Thank you for sharing Rio's peaceful departure.....it brings tears to my eyes as I am facing the inevitable with my Gypsy. I have had to say farewell to quite a few dogs in my 51 yrs as a dog lover.... None of the goodbyes easy, each one different. Most of my dogs have lived to be 13or 14yrs old so at 9 1/2 Gypsy is still young to me. I never imagined we would have to be thinking about losing her so soon. The heartache is almost unbearable but I try to not let her see how sad I am by being upbeat around her. She's still active & happy for now so we will try & savor each & every day. Thoughts are with you....... Gypsy's mom MyGypsy Wed, 30 May 2012 00:00:00 GMT Marianne, that sounds like a very nice way to go. What a great vet! I am so sorry that you had to do it but at least he is not in pain anymore, or uncomfortable. He can pee on every bush up there now! Claire amberye Wed, 30 May 2012 00:00:00 GMT Thank you so much Karin and to everyone else who reached out to me.  Rio had a very peaceful journey this morning.  We met the vet in the park by the river.  He pranced down to the water and took a big drink!  Of course, he could not pee afterwards, but that didn't stop him from trying.  He laid on his blanket under a large tree so we could say goodbye.  I got to tell him what a good dog he was, how he had filled a major void in my life, and how he could relax and go to sleep because his work here was done.  I told him he would soon be chasing deer and prairie dogs and squirrels.  I believe someday we will meet again in a better place.  I love all of you and intend to keep reading about you and your journies. Marianne Iloverio Wed, 30 May 2012 00:00:00 GMT It breaks my heart to hear about Lola and Rio.  My thoughts and prayers are with you.  We are never prepared for the day this journey ends, but we keep fighting and hoping that we can keep the journey going. We have to try and take some comfort in knowing that we have done all we could and that they are no longer suffering. Karin Baileysmom97 Wed, 30 May 2012 00:00:00 GMT On May 29, 2012 4:17 AM Aragosta wrote: And Lola is gone... She went about 18 months from being diagnosed, which we consider a blessing. All but the last 5 weeks have been great. In the end she stopped eating and become more listless.  Friday was great... she started eating again in a big way, was chasing squirrels, was her old self to a degree. That night she found a corner of the house she never went to and laid there.  It took us some time to find her on Saturday morning.  She went outside, was violently ill, and was obviously suffering greatly.  The decision we had been waiting on became very clear... it was time.  The best and worst thing we ever did. Love and best wishes to you all.     I am so sorry for your loss of Lola. It seems Lola went out with a bang....good eats....good chase, just like a beagle should. You did very well with her and she got to be with you for 18 more months than she would have without your love and caring.  Even her last day was spent with YOU....loving her till the end. ChicasMom, Lynn ChicasMom Wed, 30 May 2012 00:00:00 GMT My heart aches for you, I'm crying with you, so sorry. We are all in the same journey only in different stages. I know there is coming a day not far away I will have to make this ultimate final decision for the only true love of my life. They say time heals but I know there will always be an emptiness that can't be filled. May God be your source of strength & comfort in the future. Deb tryeverything Wed, 30 May 2012 00:00:00 GMT  I am so very sorry to read this. I am crying for you. I did read The Art of Racing in the Rain, what a great book! So maybe you will meet Rio again someday, in a different form. Lots of love. Claire and Amber amberye Wed, 30 May 2012 00:00:00 GMT I can't tell you how sorry I am about Rio.  I have gotten so much out of your posts during Rio's illness. You have worked so hard to keep Rio happy and give him a good quality of life, both with conventional and alternative medicine.  I will miss your posts and also miss Rio as I've gotten to know him through your posts.  I know you are heartbroken and you will continue to be in my thoughts and prayers, Love,  Nita Nita Tue, 29 May 2012 00:00:00 GMT I am going to have to say goodbye to my best friend tomorrow.  He was diagnosed 8 months ago.  We have done chemo, inserted a stent and given him home-cooked foods, Chinese herbs and done acupuncture.  Now it is his loss of appetite and inability to eliminate that is making him very weak.  He has barely eaten in the last 3 weeks.  He has no energy, and I have to coax him to get him into the car to go to my office every day.  To see him fade away from me is unbearable.  When he was diagnosed, the one thing I took solace in was that he would never have to suffer.  I made him a promise, but it is so hard to keep.  I know that his work here is done.  Everyone, please read "The Art of Racing in the Rain."  It puts things in the dog's perspective.  I am crying so hard.  My heart is broken. Iloverio Tue, 29 May 2012 00:00:00 GMT So sorry. The sadness is overwhelming I know. You did all you could and most of all you loved her very much and she knew it. So the best I can say is remember the good times. My heart goes out to you. Shelbysmom2 Tue, 29 May 2012 00:00:00 GMT From one beagle lover to another, I am so very to hear of Lola's passing.  Such a loss. Hugs and prayers- Copper's Mom CoppersMom Tue, 29 May 2012 00:00:00 GMT So sorry to hear about Lola.  Such a difficult thing to go through and my thoughts and prayers are with you and your family. Love, Nita Nita Tue, 29 May 2012 00:00:00 GMT I'm so sorry for your loss... Chris cgallo02 Tue, 29 May 2012 00:00:00 GMT On May 29, 2012 4:50 AM amberye wrote: I am so sorry! What kind of dog was Lola? What a horrible thing this is. My thoughts are with you. A beagle mix. Mid sized girl... 40-45lbs.  Aragosta Tue, 29 May 2012 00:00:00 GMT My 12yr old maltese x, Andy, was diagnosed 3wks ago with tcc with about 3mths tops. I found & bought Dr Steven Eisen's e-book "Dog Cancer Advise". It has brought a lot of hope even vidoes through the book on how to cook the food he suggests. He suggested Vascustatin for tumors & also Aveultra used for people with cancer. I'm waiting for my order to come, holding my breath every day. At the moment he's on K9Immunity with K9Transfer with DHA I have doubled the doses & at night on an empty stomach 1capsule of Artemix dissolved in a little warm milk. Because of his need to urinate constantly (very distressing) he has started Metacam tonight also I'm going to start Arginine. Chemo is not an option. This is such a emotional roller coaster. Has anyone heard of Hydrazine sulphate tryeverything Tue, 29 May 2012 00:00:00 GMT I am so sorry! What kind of dog was Lola? What a horrible thing this is. My thoughts are with you. amberye Tue, 29 May 2012 00:00:00 GMT And Lola is gone... She went about 18 months from being diagnosed, which we consider a blessing. All but the last 5 weeks have been great. In the end she stopped eating and become more listless.  Friday was great... she started eating again in a big way, was chasing squirrels, was her old self to a degree. That night she found a corner of the house she never went to and laid there.  It took us some time to find her on Saturday morning.  She went outside, was violently ill, and was obviously suffering greatly.  The decision we had been waiting on became very clear... it was time.  The best and worst thing we ever did. Love and best wishes to you all.     Aragosta Tue, 29 May 2012 00:00:00 GMT Hi Claire!! OK-sounds like the cran-tabs are helping you, so I'll try it..Otis was doing so well, and then a few days ago he went off again-I think it's because of the UTI, but who knows..like you, I'm blame alot on my imagination, but I have to say it's up and down-last weekend he was like his old self, then a few days ago he started acting goofy... His blood count was good-a little low on the WBC, but not in the range for risk of infection....The oncologist was happy with the results-even said he felt his prostate was smaller in length, which is a really good sign-still flat poopies, but not straining nearly as much. There's blood in his urine with clots at times..is this the infection? the cancer? the tumor sloughing? Who knows.. Is this why he seems uncomfortable? Who knows--wish they could talk... Thanks for the input..so happy Amber is doing well!! I see that as a good sign! Chris   cgallo02 Fri, 25 May 2012 00:00:00 GMT Hi Chris, I've been giving Amber cranberry juice capules every day for a while now and she hasn't had a UTI since the last one cleared up about three months ago. I have a hard time getting her to eat the capsules wrapped up in food so I've been opening them up and sprinkling them on her food, I'm sure she LOVES the taste of that, not! But she does eat it. I have the bottle right here, 475 mg and it says for a human to take two capsules, twice daily so I've been giving her one in the am and two in the pm. I also read that vitamin c could be useful for this but I'm not sure how much you can give a dog. Anything to keep the urine on the acidic side I think is good. Someone mentioned making cranberry juice jello? Though I doubt Amber would eat that! Last Thanksgiving I gave her a bowl of people dinner, including the cranberry sauce, all mixed up. She very carefully picked everything out except the cranberries. How was Otis' bloodwork? Amber did have slightly lowered WBC count and lymphocites but everything else looked normal, my vet was happy with the results. Amber is eating well, playing, running, she seems good! Maybe even a tiny bit better than she has been lately or it could be my imagination. Claire amberye Thu, 24 May 2012 00:00:00 GMT Hi everyone!! anyone have any thoughts regarding cranberry tabs to ward off UTIs??  Has this helped or worked for anyone?? Chris cgallo02 Thu, 24 May 2012 00:00:00 GMT Hi Debbie!! Hopefully the Tramadol will at least keep her comfortable-Otis just got over a UTI and it came back-and boy does it make him miserable...Maybe I'll try the cranberry tabs..can't hurt I suppose.. Maybe Peaches, or the bacteria in her bladder, has built up a resistance to the antibiotics?? Have you tried Clamovox? That has amoxicillan, and something else..I forget what-I thought I read that a resistance could not be built up against this drug?? (Unless I misunderstood) Hoping she feels better soon... Chris cgallo02 Thu, 24 May 2012 00:00:00 GMT I think I had read that in one of your other posts.  Will keep you in my thoughts and hoping that she continues to improve. Karin Baileysmom97 Thu, 24 May 2012 00:00:00 GMT Thanks - we already know that it had spread to her sub lumbar lymph nodes, an x-ray taken 4/26 showed the enlarged lymph nodes but the spine looked good - she is as painful then as she is now.  Increased her tramadol a bit, and have her on antibiotics right now, and she seemed a touch better yesterday - so hoping it continues. Sue & Dazz suebon Thu, 24 May 2012 00:00:00 GMT If it has spread to the bones, you would probably want to do an xray rather than ultrasound.  After Bailey had the surgery, her doctor showed me her xray which clearly showed her uretal stents and the doctor pointed out that her spine looked good, especially in the area above the tumor in the bladder.  Everything was clear and sharp.  I believe she said something to the effect that the bone would appear fuzzy and not have clear edges if the cancer had spread to the bones. The problem is if has spread, there's not much that can be done, however, perhaps there is a chance that it is something else.  That may be worth knowing. It is indeed very sad for all of us.  Baileysmom97 Wed, 23 May 2012 00:00:00 GMT Hi Chris, Yes, UTI still there.  Just talked to her doctor yesterday and she told me she will probably have it the rest of her life.  And every month we will just switch out different kinds of anitbiotics to keep her on to keep the infection at bay.  This really SUCKS!  She recommends yet another ultrasound to see how much the cancer has progressed.  And also to increase her dosage of Tramadol. Debbie MyPeaches Wed, 23 May 2012 00:00:00 GMT So sorry about Copper.  I do think her cancer has spread to her vertebrae.  What I am not understanding is why this has happened so quickly.  I saw no symptoms the past 8 months - or very very subtle ones so am just mad that it has affected her so bad and so quickly.  She is hanging in there.  I talked to my vet and she did not feel it was worth even doing an utlrasound at this point.  She continues to eat a ton and then to add insult to injury came down with kennel cough.  I guess I just keep her as comfortable as possible, and she is able to still get up and down ok - but slower than normal.  This is all very sad and I feel for anyone having to go through it. Sue suebon Wed, 23 May 2012 00:00:00 GMT Hi everyone So sad hearing everyones stories! Thoughts go out to you all. Poppy has just finished her last chemo and she had been really off her food between the last two rounds. She had blood tests yesterday to check her kidney and liver function and it is showing that there has been a considerable change to her kidney function between the last test 6 weeks ago when it was normal and today. I've been advised to stop the piroxicam imediately and bring in a urine sample to see what that shows. Has anyone else had this? What were the next steps? Cheers in advance, Esther. poppy06 Wed, 23 May 2012 00:00:00 GMT Hi Sue, So sorry to hear about Dazzle's difficulties.  I have heard of canine TCC spreading to the bones, so your idea of further diagnostic testing seems good to me.  Also, maybe more and/or different pain control could be needed now.  This is so hard and you and Dazzle will be in my thoughts and prayers.  Love, Nita Nita Tue, 22 May 2012 00:00:00 GMT I'm so hoping for good news for Siena. Shelby's tumor stayed the same for 4 months before it disappeared. I thi k the diet is right on too. Shelby is developing difficulty in her hind legs and from what I'm reading on here I'm fearful it my have spread to her spine now. However the vet said she has arthritis in her spine pretty bad. Also I've read that the Neo will kill any cancer wherever it is so I don't know why it would be there. I'm getting discouraged but still think Neo is a great treatment for some dogs due to our experience. It's just too bad Shelby was not younger. She's 14. How old is Siena. I think it's a great treatment for a young dog. I'll keep everyone posted. Shelbysmom2 Tue, 22 May 2012 00:00:00 GMT On May 21, 2012 7:21 PM Baileysmom97 wrote: On May 09, 2012 10:55 PM SienasMom wrote: That is so true! I did a lot of research and chose to treat Siena with neoplasene because it had less side effects and better success than traditional treatments. I went to a highly trained oncologist and all she would do was surgery/radiation/chemo and they had very low success rates. Just as with human doctors, think that natural or plant based remedies are not taught at schools, just pharmaceutical ones. its a shame. Siena has been on it for a month, is tolerating it beautifully and her tumor is shrinking. What more can I ask from a treatment? I was lucky enough to find a vet that has experience using it, and belives in the treatment. She has had remissions in several dogs, which is the best news of all.Could you tell us what dosage Siena is on and how much she weighs?  Are you also following the diet recommended by Dr. Fox.  I think it would be of great benefit to all if those of you who are using the Neoplasene could post updates.  Siena is a 54 pound border collie and gets 1cc of neo twice a day, after meals. I mix the medicine into a few spoonfuls of cottage cheese and she woofs it down and licks the bowl clean. I follow Dr. Fox's diet, with some exceptions.  I feed her a mixture of 80% homecooked meat (whatever is on sale - chicken, beef, pork) and 20% cooked veggies with a low glycemic index (broccoli, cabbage, cauliflower, spinach, kale, tomatoes, red bell peppers). She eats better than I do some days! I don't give her rice, which is part of Dr. Fox's diet, because she hasn't had any nausea or problems with appetite. Since she doesn't need it, I don't want to give her any carbs. She doesn't get any dog food or kibble at all. Its a pain some days, but I believe that diet is important to inhibit the growth of the tumor. She has her next check up on Friday afternoon, I'm hoping for more good news! I'll post an update. SienasMom Tue, 22 May 2012 00:00:00 GMT Sue-  I am sorry to hear about Dazzle.  I lost my beagle, Copper, last March after he was diagnosed in August 2010.  I would encourage you to have the ultrasound done.  At the very end, Copper loss the use of his hind legs and while I was never told, I am sure that the cancer spread to his spine.  For 7-10 days leading up to his last day, he would have trouble getting his legs under himself after laying down.  When he was no longer mobile, I had to let him go. Do take care of yourself during all this.  It is so difficult to watch our babies diminish with this nasty disease. Peace-  Copper's Mom   CoppersMom Tue, 22 May 2012 00:00:00 GMT I am reposting on the "big list" since I did not know how to do when I first joined.  My sheltie Dazzle is not doing well after being diagnosed with TCC that has spread to her sub lumbar lymph nodes.  She had her first UTI with bladder stones last August, and was totally cleared up and stones gone on a special diet by end of September.  A routine urinalysis in March showed no blood or infection.  She started having some difficulty jumping on my couch, and into the van and I noticed her having difficulty with the stairs - this started around the beginning of April.  Mid April I took her in and ran another UA - blood and infection and x-ray showed something under her spine - so did an exploratory surgery where it was found her lymph nodes were enlarged so biopsy sent off and came back as TCC - but the vet never checked her bladder so not sure exactly where the tumor is.  She has gone dowhnill and is having alot of difficulty getting up and down, and doing even one stair but is eating a ton.  She was on rimadyl but switched to piroxicam and tramadol and on a bunch of holistic things.  I have read that many dogs are doing ok (and personally know two shelties that continued to compete and be ok for at least a year after diagnosis) and do not understand her extreme pain.  I am considering doing an ultrasound to determine where the tumor is?  I feel helpless and cannot believe she ran in an agility trial as fast and furious as ever last month and to see her now is heartbreaking only a month later.  Perhaps it has spread to other areas (bones??) and that would explain the pain? Sue     suebon Tue, 22 May 2012 00:00:00 GMT Hi, my name is Kim I am Penelope's mom.  I am so sorry for everything you are going through.  I will say a prayer for you and your baby.  My baby was diagnosed with TCC in March and just had her 3rd chemo treatment with vinblastine last week.  Her 2nd ultrasound today showed her tumor has gotten larger and in March she had a stent put in on an emergency basis, she could not urinate.  She does leak I put a diaper on her.  She is a happy, sweet 10 1/2 year old pug, our baby.  I cry everyday.  We are going to try a different chemo hopefully next week.  Every chemo is different and what works for some does not work for others.  I wish you well and will talk to you soon.  Have a good night. penelopesmom Tue, 22 May 2012 00:00:00 GMT On May 09, 2012 10:55 PM SienasMom wrote: That is so true! I did a lot of research and chose to treat Siena with neoplasene because it had less side effects and better success than traditional treatments. I went to a highly trained oncologist and all she would do was surgery/radiation/chemo and they had very low success rates. Just as with human doctors, think that natural or plant based remedies are not taught at schools, just pharmaceutical ones. its a shame. Siena has been on it for a month, is tolerating it beautifully and her tumor is shrinking. What more can I ask from a treatment? I was lucky enough to find a vet that has experience using it, and belives in the treatment. She has had remissions in several dogs, which is the best news of all.Could you tell us what dosage Siena is on and how much she weighs?  Are you also following the diet recommended by Dr. Fox.  I think it would be of great benefit to all if those of you who are using the Neoplasene could post updates.   Baileysmom97 Mon, 21 May 2012 00:00:00 GMT Hi Chris, It is very helpful reading about your experiences with Otis, so thanks for taking the time to write it down! Amber hasn't vomited or had any diarrhea, thankfully. We go for blood work on Thursday, so funny that we're practically on the same schedule. Good luck with your next treatment! amberye Mon, 21 May 2012 00:00:00 GMT Hi Kayla's Mommy!!  So sorry for all your troubles..and for the loss of Casey.. Otis just started on Vinblastine...too soon to know anything yet-he tolerated it well..we will be alternating with Mitoxantrone. I'll be seeing his oncologist on Wed.-I will ask him about the radiation therapy-he mentioned it to me as an option for Otis if chemo does not work-he emphasized that it is new and to go to a facility with experience and a radiation oncologist on site...I have also been looking into intra-arterial chemotherapy (done in Manhattan, NY by Dr. Weitz sp?)they inject a potent dose of chemo into the tumor via the artery-this should shrink the tumor without the entire body being exposed to the large amount of chemo-it's experiemental, but sounds reasonable to me. If chemo does not work, I will consider intra-arterial chemo or radiation. If the one ureter closes off, she still has another kidney-but the question is, what kind of shape is that kidney in?  I would get off the high protein diet.. You're taking such good care of Kayla-God Bless you..keeping Kayla and you in my thoughts.. Chris cgallo02 Mon, 21 May 2012 00:00:00 GMT Thank you Nita...they can put a man on the moon, but nobody can figure out cancer?? With all the brilliant people in this world?? I've noticed with Otis alot of ups and downs...maybe Rocky will perk up... What chemo does he get? Nine months is pretty long.I read somewhere that Vinblastine can be taken long term?? Chris cgallo02 Mon, 21 May 2012 00:00:00 GMT Hi Kayla's mommy-- Sorry to hear about the loss of Casey and all the other terrible things going on.  I've been on some of the human messages about bladder cancer and I haven't read too much good stuff about radiation.  It seems to change the structure of the bladder. My dog Bailey seems to also have some kidney issues and last October they changed her diet to a lower protein, more carb diet.  Then in January, her tumor started growing more and in March we did a round of Carboplatin which was horrible and did nothing to slow the tumor.  We even tried surgery but when they went in, the surgeon saw the tumor was much closer to the ureters than it appeared on ultrasound.  So they put in uretal stents, closed her up and I've now switched her back to a "cancer" diet which is more protein, less carbs.  It's always so hard, because you never know if you're doing the right thing. I would maybe look into neoplasene.  In case you haven't read the story, I think it was Shelbysmom who had it done and it successfully got rid of the tumor.  In addition, there are two other dogs that are on it at the present time, oral doses.  I'm trying to get my specialist to look into it and perhaps give it a try.  My local vet did not want to try it because in her opinion it required a high dosage and this would be too much of an irritant.  So far the dogs that have been on it, do not seem to have too many issues. Hope things get better for you. Karin Baileysmom97 Mon, 21 May 2012 00:00:00 GMT Hi Claire!!  Thanks for the condolences... Well, Otis vomitted just a tiny bit this am, otherwise he's ok--and who knows if that was from the chemo (I wonder if it is the green tea extract..same thing happened 2 weeks ago, and I stopped it at that time, and started again 2 days ago)-Trouble is when something happens, they're on so much stuff, you don't know what to blame-although I have to say, between yesterday and today, he's almost like his old self... We go for blood work Wed to check blood count and then the following Wed for another treatment-this time Mitoxantrone-unless the oncologist can feel the tumor shrinking, we'll stick with Vinblastine... If he gets very sick, or stops eating I will be concerned..but we'll deal with a little mopey to put this into remission. I hope Amber is a little perkier...I bet she will be in a few days..their bodies need time to recover. Chris cgallo02 Mon, 21 May 2012 00:00:00 GMT On May 20, 2012 11:10 PM LoveMyKayla wrote: Hi everyone, (Sorry ahead of time - this is a long post) I deeply apologize from the bottom of my heart for not responding to the messages that were posted in regards to my first post about Kayla back in December.  I have read each and every one and I’m very grateful for the time you have taken to help me take care of Kayla.  I want to explain what has happened with Kayla, me and our family since I originally posted, so that everybody can understand why I have not been able to respond until and what has happened with Kayla during the months since I first wrote about her. I also want to extend my deepest sympathies to those that have lost their sweet dogs since I have been on the forum.  I wish I had been on here to respond to each of you individually, and I will try to over time.  I know even if you haven’t lost yours yet, just getting the TCC diagnosis and living with it and through it is a grieving process.  I cry with all of you for your pain and I also wish you healing and peace. First, some outside complicating factors came in that prevented me from posting on the board.  Within a week of posting my first message in December, I became deathly ill with an infection. I had to have emergency surgery and I was down for weeks, both from the recovery over the surgery and allergies to the antibiotics I was taking.   Since that time, I have been extremely ill in one form or another.  I’ve never really recovered from that infection.  I’m angry that I’ve been sick through all this. Then on March 31st, Kayla’s sister Casey and my sweet baby girl died unexpectedly and very quickly in the early morning hours from full torsion GDV (her stomach and spleen twisted 360 degrees upside down).   This is more commonly referred to as “bloat” but that is just the condition that leads to GDV.  Some dogs only have bloat and never progress to GDV.  It was traumatic to watch, confusing and chaotic and fast and unexpected.  She went into cardiac arrest five times and on the sixth, after they let Kayla in who gave her a kiss on the nose, they removed the ventilator and she was gone.  We were completely unprepared for this.  The loss of Casey has devastated our family.  Kayla has been lost without her, looking in corners for her sister and staring at the empty space in her bed where her sister used to lie beside her. It’s for these reasons, that I have just not had the energy – both physically and emotionally – to all of your posts.   I’m very sorry for not saying this sooner, but I am very grateful for all of your kindness and concern. I’m so proud Kayla has made it this far since her diagnosis in late November, 2011.  But it has not been easy.  Here is what has happened on her journey:  We work with both an internist at a vet hospital here where I live and oncologists at University of Tennessee (UT) in Knoxville Vet School/Clinic, about 2 hours from here.  FIRST TRIES:  We consulted with Nutrition Services at UT for a diet and supplements, but Kayla has a sensitive tummy and never was able to take most of what was offered here on the board or by UT.  I chose to do the “standard” treatment of mitoxantrone and Piroxicam, starting in December.    She did not react well to the combined stress of the chemo and the Piroxicam, and would barely eat for days afterward.  On the recommendation of our vet, we stopped the Piroxicam in the month of December to give her body time to heal itself.  She did eventually return to a more “normal” level of appetite, but her food consumption has been a worsening problem since she began chemo.  It was a problem before cancer even came around; a prolonged course of Prednisone a few years ago did a lot of permanent damage to her. In January we started her back on Piroxicam and from that moment on tried different dosing; every other day, every day, one week off one week on, etc.  Finally the oncologist lowered her dosage and she takes it every day now.  KAYLA’S CURRENT STATUS:  Kayla has TCC in a large portion of her bladder, all the way up and down her urethra, and up into her right ureter into her right kidney. We have been able to maintain stable disease in her bladder and urinary tract until a few weeks ago.  She now has additional bladder tumors and thickening of the one in her urethra.  Her cancer upon diagnosis had only one suspicion of spreading; a tiny dot on her lung.  However, this grew and was confirmed to be metastasis of the TCC.  Since then, she has had enlargement of existing nodules and new nodules forming, with a formal diagnosis now of metastatic lung cancer.  It is not symptomatic yet, and we hope it never will be. Kayla has had numerous UTI’s, including Strep, E Coli, and others.  She also has had pyelonephritis (infection) of the left kidney (the one not being affected by TCC tumors) and had a month long antibiotic course of amoxicillin to clear that up.  She has also been on Baytril, which had to be dosed at a reduced dosage because it is excreted through the kidneys and was hard on her.  She was also tried on Flagyl two separate times and had bad reactions both times so it had to be discontinued. In January she was diagnosed with renal (kidney) failure/insufficiency.  This has complicated and narrowed our treatment options. The rest of her treatment plan has been as follows: 5 treatments of Mitoxantrone chemo performed every three weeks, ending somewhere around March.  This always made her lethargic and have GI issues and low WBC counts, so she did not tolerate it as well as other dogs I have heard about, but she also wasn’t severely ill and always rebounded so we continued the treatments and her health remained fairly stable and you could not really tell she had cancer MOST of the time (except for the constant urinating). 1 Carboplatin treatment three weeks after the Mitoxantrone chemo ended.  She tolerated this pretty well as far as her outward symptoms went.  However, 7 days post treatment her kidney values had worsened dramatically, she became slightly anemic, and her white blood cell count and other bloodwork values were very bad. 1 Vinblastine treatment 3 weeks following the Carboplatin chemo since the doctors were concerned about her kidneys.  This vinblastine chemo has only one study with about 23 or so dogs done on TCC.  There is no real evidence beyond that study that confirms this is an effective treatment for her.  She was the first dog at UT to receive vinblastine for TCC. She got very ill after this.  The GI side effects were horrible, her bloodwork was bad (although her kidney values were MUCH better) and she ended up becoming very ill with pancreatitis and gallbladder/liver disease.   This was supposed to be an every 2 week chemo course, but we decided to not use it again after it either caused already existing problems to flare or was the main cause for her pancreas, gallbladder, liver, and GI issues. 1 additional treatment of Carboplatin was performed three weeks later.  Although her liver and pancreas values had gotten much better and her kidney values had stabilized, she had obviously not fully recovered from her pancreatitis.  She vomited every day for a week after this Carboplatin, which she had never done with Mitoxantrone or previous carboplatin treatment.  Her 7 day post-chemo bloodwork looked fine, but at 14 days post chemo it showed the Carboplatin hit her kidneys hard and knocked her anemia and white blood cell count to the lowest they had ever been. She was due for her next chemo last Thursday.  Due to her reaction to the Carboplatin and the fact that she had a urine culture come back positive for E Coli, the doctors decided it was best to postpone it for a week so her body would have more time to adjust back to normal and her infection would have time to get better with antibiotics (Keflex/cephalexin). Now I am at a crossroads because her last staging visit showed more tumors in her bladder and thickening of the one around her urethra.  I have to make a decision for next Thurday’s chemo.  My options are: 1.        Continue Carboplatin at a reduced dose to protect kidneys while knowing this may not and probably will not do anything to fight the cancer. 2.     UT Head of Oncology wants to use a treatment called hyperthermia with the Carboplatin on the area of her bladder, where he is worried about occlusion occurring.  This is a treatment that he himself admits is experimental, he has only used on a few dogs for TCC, and can cause side effects too numerous to mention.  On a dog that has TCC but is otherwise healthy, this would be a safe route to go.  The doctor is very confident in trying it, but he also ALWAYS minimizes risk and side effects.  In Kayla’s case, I worry she is so fragile that this would be too much for her.  3.       The UT Head of Oncology also wants to try radiation for certain parts of the bladder tumor.  This is typically not recommended for TCC due to the sensitive nature of the bladder and proximity to the GI tract.  I’m sure many of you have read up on the side effects.  The radiation specialist contacted me via email to assure me that most likely it would safe except possibilities of perforation of tissue and colitis (which Kayla already has colitis; we cannot handle any more GI issues).  Also, she would have to be fully sedated each time, which is dangerous because of her kidneys.  I have pretty much ruled this out, but am open to suggestions.  The doctors are very clear in the fact that Carboplatin or any chemotherapy alone (and with Piroxicam) will not be enough to achieve stable disease and they believe we can achieve that through these methods and are really pushing me to do them.   Her internal medicine doctor at the hospital here who has been treating her for 4 and a half years trusts their opinions and respects them as being highly intelligent, but does not fully support radiation and says it’s really all experimental and that without data for him to go on, it is my choice.  This is a terrible strain to decided medical decisions and have doctors who have such differing opinions and no data for me to rely upon!!  The biggest problem aside from kidney failure has been Kayla’s lack of appetite, difficulty feeding, and GI issues.  We have had to change diets so many times.  The doctors began to recommend moving Kayla away from the high protein cancer diet she had been on, to the opposite diet which is for renal failure.  After her pancreatitis, which is chronic, her diet has now been switched again to a very, very low fat diet (not very cancer friendly).  Even before her cancer, Kayla had appetite problems due to damage done by a long time use of Prednisone she took for an unknown autoimmune problem.  She stopped it in 2010 but has never been the same.  She used to be a 70 pound dog (sometimes more), and at time of her TCC diagnosis was 50 pounds.  She lost most recently down to 39 pounds, and we have managed to get her to gain to 41 pounds.  We give her mirtazapine daily now, and if it is doing anything it’s not a miracle worker by any means.  Feeding her takes more than 4 hours a day.  She will eat food off the floor, be hand fed, and sometimes eat on her own depending on her mood, and she tires of foods within a day which is a challenge. I’ve listed Kayla’s medications below, and below that are my questions.  If anyone could answer these, I would GREATLY appreciate it.  I am in the midst of grieving for my baby Casey and taking care of sweet Kayla.  I am also wondering how much grief or confusion that her lifelong companion is gone has had an effect on Kayla’s health (mentally and physically), as she got really ill about 4 days after Casey’s death. As a side note, I am not a cruel person and would not continue treatments if a) the vets said there was nothing left to do (which they haven’t; all have recommended continued treatment) and b) if Kayla was miserable and sick all the time.  She isn’t.  She goes on walks every day.  She runs faster than I can!  She plays with her toys, cuddles with me, and yes she is tired a lot but she is also very active, happy, and alert a LOT.  I have never seen her urinate blood (there are traces of it in each urinalysis) and she does have to strain to urinate and goes quite a bit, but she still urinates quite well considering the advanced stage of her diseases.  She loves going to Petsmart and Petco and dog parks and interacting with dogs and people, and she even likes going to the vet!  So although I have listed a lot of problems here and although she goes through some very rough battles, she is still very much an “alive” dog with an active spirit.  I know her time is coming soon(we have already bought her casket, dug her grave, and prepared her pictures and toys for inside the casket so I am definitely realistic about this) but my goal is to give her the best treatment possible to extend her life as long as possible BUT balancing that out with her quality of life.  I am not shoving treatments at her in a desperate attempt to cure the incurable.  They have worked and kept her alive this long, and she has had so many happy memories she would have otherwise not had if we had not done any treatment or had her euthanized.  I just wanted to let you all know the good things about her, also, so that it doesn’t sound like she is being tortured just for my desire for her to be alive.  If I ever see her suffering with no chance of recovery, I am ready to make the decision then to stop treatments. Anyway, here are her medications and following are my questions.  Please, please help.  And thank you all for your support, especially if you have read this far!    Here’s what Kayla is taking these days for medication: 500 mg sub-q fluids a day 4 mg Piroxicam a day 75mg Tramadol twice a day 100mg Gabapentin twice a day 20mg Prilosec once a day 300mg Actigall once a day 425 mg Denamarin once a day 11.3 mg Remeron once a day (her vet has recently authorized an increased dosage to 11.3mg once a day) 250 mg cephalexin three times a day for E Coli ½ pack of VSL #3 once a day, a probiotic Carafate (slushie), one tablet twice daily Questions: 1.       Has anyone had any experience with Vinblastine and if so what was it? 2.       Has anyone had experience with hyperthermia treatment with chemotherapy? 3.       Has anyone dealt with TCC being in the ureter and causing renal failure? 4.       Does anyone have experience or comments/knowledge about “focal” radiation treatment for TCC in the bladder? 5.       If we insert a stent into her urethra, will she be dribbling all of the time and need a diaper?  Will this increase her discomfort or make it better?  Does this increase UTI infections? 6.       After reading this, are there any diet/supplement/medication/treatments you think might benefit Kayla or would at least be worth looking into? Thank you all again so much!! Kayla’s MommyMy beagle was dx on Jan. 2 for TCC. I live in Knoxville and use an oncologist that use to teach at UT. He uses the hyperthermia on Chloe when she has chemo. The tumor had shrunk some after 3 rounds of mitoxantrone, 3 weeks apart. The next ultasound showed some growth down her urethra. We changed to Carboplatin which made her very sick and no appetite for almost 4 weeks. Latest ultrasound showed some more shrinkage of the tumor at the urethra area. She did have hyperthermia at the time of the chemo. We are just waiting for her appetite to come back completely and then we are doing another round of Carboplatin with heat treatment. He is going to reduce the dosage this time. Sorry for all you have been through and for what we are both facing in the near future. Hoping things get better for you and your baby! Susan, Chloe's mom Chloebeaglemom Mon, 21 May 2012 00:00:00 GMT I apologize for not responding to any private replies.  I agree this site is not functioning properly.  When I receive emails that there is a private reply, that page is not found when I click on it. Iloverio Mon, 21 May 2012 00:00:00 GMT Nita, Thanks for your words. Yes, I just need to learn to think like a dog! August was when he was diagnosed? I am so glad he's had so long with you! Claire amberye Mon, 21 May 2012 00:00:00 GMT Hi everyone, (Sorry ahead of time - this is a long post) I deeply apologize from the bottom of my heart for not responding to the messages that were posted in regards to my first post about Kayla back in December.  I have read each and every one and I’m very grateful for the time you have taken to help me take care of Kayla.  I want to explain what has happened with Kayla, me and our family since I originally posted, so that everybody can understand why I have not been able to respond until and what has happened with Kayla during the months since I first wrote about her. I also want to extend my deepest sympathies to those that have lost their sweet dogs since I have been on the forum.  I wish I had been on here to respond to each of you individually, and I will try to over time.  I know even if you haven’t lost yours yet, just getting the TCC diagnosis and living with it and through it is a grieving process.  I cry with all of you for your pain and I also wish you healing and peace. First, some outside complicating factors came in that prevented me from posting on the board.  Within a week of posting my first message in December, I became deathly ill with an infection. I had to have emergency surgery and I was down for weeks, both from the recovery over the surgery and allergies to the antibiotics I was taking.   Since that time, I have been extremely ill in one form or another.  I’ve never really recovered from that infection.  I’m angry that I’ve been sick through all this. Then on March 31st, Kayla’s sister Casey and my sweet baby girl died unexpectedly and very quickly in the early morning hours from full torsion GDV (her stomach and spleen twisted 360 degrees upside down).   This is more commonly referred to as “bloat” but that is just the condition that leads to GDV.  Some dogs only have bloat and never progress to GDV.  It was traumatic to watch, confusing and chaotic and fast and unexpected.  She went into cardiac arrest five times and on the sixth, after they let Kayla in who gave her a kiss on the nose, they removed the ventilator and she was gone.  We were completely unprepared for this.  The loss of Casey has devastated our family.  Kayla has been lost without her, looking in corners for her sister and staring at the empty space in her bed where her sister used to lie beside her. It’s for these reasons, that I have just not had the energy – both physically and emotionally – to all of your posts.   I’m very sorry for not saying this sooner, but I am very grateful for all of your kindness and concern. I’m so proud Kayla has made it this far since her diagnosis in late November, 2011.  But it has not been easy.  Here is what has happened on her journey:  We work with both an internist at a vet hospital here where I live and oncologists at University of Tennessee (UT) in Knoxville Vet School/Clinic, about 2 hours from here.  FIRST TRIES:  We consulted with Nutrition Services at UT for a diet and supplements, but Kayla has a sensitive tummy and never was able to take most of what was offered here on the board or by UT.  I chose to do the “standard” treatment of mitoxantrone and Piroxicam, starting in December.    She did not react well to the combined stress of the chemo and the Piroxicam, and would barely eat for days afterward.  On the recommendation of our vet, we stopped the Piroxicam in the month of December to give her body time to heal itself.  She did eventually return to a more “normal” level of appetite, but her food consumption has been a worsening problem since she began chemo.  It was a problem before cancer even came around; a prolonged course of Prednisone a few years ago did a lot of permanent damage to her. In January we started her back on Piroxicam and from that moment on tried different dosing; every other day, every day, one week off one week on, etc.  Finally the oncologist lowered her dosage and she takes it every day now.  KAYLA’S CURRENT STATUS:  Kayla has TCC in a large portion of her bladder, all the way up and down her urethra, and up into her right ureter into her right kidney. We have been able to maintain stable disease in her bladder and urinary tract until a few weeks ago.  She now has additional bladder tumors and thickening of the one in her urethra.  Her cancer upon diagnosis had only one suspicion of spreading; a tiny dot on her lung.  However, this grew and was confirmed to be metastasis of the TCC.  Since then, she has had enlargement of existing nodules and new nodules forming, with a formal diagnosis now of metastatic lung cancer.  It is not symptomatic yet, and we hope it never will be. Kayla has had numerous UTI’s, including Strep, E Coli, and others.  She also has had pyelonephritis (infection) of the left kidney (the one not being affected by TCC tumors) and had a month long antibiotic course of amoxicillin to clear that up.  She has also been on Baytril, which had to be dosed at a reduced dosage because it is excreted through the kidneys and was hard on her.  She was also tried on Flagyl two separate times and had bad reactions both times so it had to be discontinued. In January she was diagnosed with renal (kidney) failure/insufficiency.  This has complicated and narrowed our treatment options. The rest of her treatment plan has been as follows: 5 treatments of Mitoxantrone chemo performed every three weeks, ending somewhere around March.  This always made her lethargic and have GI issues and low WBC counts, so she did not tolerate it as well as other dogs I have heard about, but she also wasn’t severely ill and always rebounded so we continued the treatments and her health remained fairly stable and you could not really tell she had cancer MOST of the time (except for the constant urinating). 1 Carboplatin treatment three weeks after the Mitoxantrone chemo ended.  She tolerated this pretty well as far as her outward symptoms went.  However, 7 days post treatment her kidney values had worsened dramatically, she became slightly anemic, and her white blood cell count and other bloodwork values were very bad. 1 Vinblastine treatment 3 weeks following the Carboplatin chemo since the doctors were concerned about her kidneys.  This vinblastine chemo has only one study with about 23 or so dogs done on TCC.  There is no real evidence beyond that study that confirms this is an effective treatment for her.  She was the first dog at UT to receive vinblastine for TCC. She got very ill after this.  The GI side effects were horrible, her bloodwork was bad (although her kidney values were MUCH better) and she ended up becoming very ill with pancreatitis and gallbladder/liver disease.   This was supposed to be an every 2 week chemo course, but we decided to not use it again after it either caused already existing problems to flare or was the main cause for her pancreas, gallbladder, liver, and GI issues. 1 additional treatment of Carboplatin was performed three weeks later.  Although her liver and pancreas values had gotten much better and her kidney values had stabilized, she had obviously not fully recovered from her pancreatitis.  She vomited every day for a week after this Carboplatin, which she had never done with Mitoxantrone or previous carboplatin treatment.  Her 7 day post-chemo bloodwork looked fine, but at 14 days post chemo it showed the Carboplatin hit her kidneys hard and knocked her anemia and white blood cell count to the lowest they had ever been. She was due for her next chemo last Thursday.  Due to her reaction to the Carboplatin and the fact that she had a urine culture come back positive for E Coli, the doctors decided it was best to postpone it for a week so her body would have more time to adjust back to normal and her infection would have time to get better with antibiotics (Keflex/cephalexin). Now I am at a crossroads because her last staging visit showed more tumors in her bladder and thickening of the one around her urethra.  I have to make a decision for next Thurday’s chemo.  My options are: 1.        Continue Carboplatin at a reduced dose to protect kidneys while knowing this may not and probably will not do anything to fight the cancer. 2.     UT Head of Oncology wants to use a treatment called hyperthermia with the Carboplatin on the area of her bladder, where he is worried about occlusion occurring.  This is a treatment that he himself admits is experimental, he has only used on a few dogs for TCC, and can cause side effects too numerous to mention.  On a dog that has TCC but is otherwise healthy, this would be a safe route to go.  The doctor is very confident in trying it, but he also ALWAYS minimizes risk and side effects.  In Kayla’s case, I worry she is so fragile that this would be too much for her.  3.       The UT Head of Oncology also wants to try radiation for certain parts of the bladder tumor.  This is typically not recommended for TCC due to the sensitive nature of the bladder and proximity to the GI tract.  I’m sure many of you have read up on the side effects.  The radiation specialist contacted me via email to assure me that most likely it would safe except possibilities of perforation of tissue and colitis (which Kayla already has colitis; we cannot handle any more GI issues).  Also, she would have to be fully sedated each time, which is dangerous because of her kidneys.  I have pretty much ruled this out, but am open to suggestions.  The doctors are very clear in the fact that Carboplatin or any chemotherapy alone (and with Piroxicam) will not be enough to achieve stable disease and they believe we can achieve that through these methods and are really pushing me to do them.   Her internal medicine doctor at the hospital here who has been treating her for 4 and a half years trusts their opinions and respects them as being highly intelligent, but does not fully support radiation and says it’s really all experimental and that without data for him to go on, it is my choice.  This is a terrible strain to decided medical decisions and have doctors who have such differing opinions and no data for me to rely upon!!  The biggest problem aside from kidney failure has been Kayla’s lack of appetite, difficulty feeding, and GI issues.  We have had to change diets so many times.  The doctors began to recommend moving Kayla away from the high protein cancer diet she had been on, to the opposite diet which is for renal failure.  After her pancreatitis, which is chronic, her diet has now been switched again to a very, very low fat diet (not very cancer friendly).  Even before her cancer, Kayla had appetite problems due to damage done by a long time use of Prednisone she took for an unknown autoimmune problem.  She stopped it in 2010 but has never been the same.  She used to be a 70 pound dog (sometimes more), and at time of her TCC diagnosis was 50 pounds.  She lost most recently down to 39 pounds, and we have managed to get her to gain to 41 pounds.  We give her mirtazapine daily now, and if it is doing anything it’s not a miracle worker by any means.  Feeding her takes more than 4 hours a day.  She will eat food off the floor, be hand fed, and sometimes eat on her own depending on her mood, and she tires of foods within a day which is a challenge. I’ve listed Kayla’s medications below, and below that are my questions.  If anyone could answer these, I would GREATLY appreciate it.  I am in the midst of grieving for my baby Casey and taking care of sweet Kayla.  I am also wondering how much grief or confusion that her lifelong companion is gone has had an effect on Kayla’s health (mentally and physically), as she got really ill about 4 days after Casey’s death. As a side note, I am not a cruel person and would not continue treatments if a) the vets said there was nothing left to do (which they haven’t; all have recommended continued treatment) and b) if Kayla was miserable and sick all the time.  She isn’t.  She goes on walks every day.  She runs faster than I can!  She plays with her toys, cuddles with me, and yes she is tired a lot but she is also very active, happy, and alert a LOT.  I have never seen her urinate blood (there are traces of it in each urinalysis) and she does have to strain to urinate and goes quite a bit, but she still urinates quite well considering the advanced stage of her diseases.  She loves going to Petsmart and Petco and dog parks and interacting with dogs and people, and she even likes going to the vet!  So although I have listed a lot of problems here and although she goes through some very rough battles, she is still very much an “alive” dog with an active spirit.  I know her time is coming soon(we have already bought her casket, dug her grave, and prepared her pictures and toys for inside the casket so I am definitely realistic about this) but my goal is to give her the best treatment possible to extend her life as long as possible BUT balancing that out with her quality of life.  I am not shoving treatments at her in a desperate attempt to cure the incurable.  They have worked and kept her alive this long, and she has had so many happy memories she would have otherwise not had if we had not done any treatment or had her euthanized.  I just wanted to let you all know the good things about her, also, so that it doesn’t sound like she is being tortured just for my desire for her to be alive.  If I ever see her suffering with no chance of recovery, I am ready to make the decision then to stop treatments. Anyway, here are her medications and following are my questions.  Please, please help.  And thank you all for your support, especially if you have read this far!    Here’s what Kayla is taking these days for medication: 500 mg sub-q fluids a day 4 mg Piroxicam a day 75mg Tramadol twice a day 100mg Gabapentin twice a day 20mg Prilosec once a day 300mg Actigall once a day 425 mg Denamarin once a day 11.3 mg Remeron once a day (her vet has recently authorized an increased dosage to 11.3mg once a day) 250 mg cephalexin three times a day for E Coli ½ pack of VSL #3 once a day, a probiotic Carafate (slushie), one tablet twice daily Questions: 1.       Has anyone had any experience with Vinblastine and if so what was it? 2.       Has anyone had experience with hyperthermia treatment with chemotherapy? 3.       Has anyone dealt with TCC being in the ureter and causing renal failure? 4.       Does anyone have experience or comments/knowledge about “focal” radiation treatment for TCC in the bladder? 5.       If we insert a stent into her urethra, will she be dribbling all of the time and need a diaper?  Will this increase her discomfort or make it better?  Does this increase UTI infections? 6.       After reading this, are there any diet/supplement/medication/treatments you think might benefit Kayla or would at least be worth looking into? Thank you all again so much!! Kayla’s Mommy LoveMyKayla Sun, 20 May 2012 00:00:00 GMT Hi Chris, so sorry to hear about your father in law.  Hopefully someday we will beat this terrible disease so that it can't take the people and the animals that we love. Love, Nita Nita Sun, 20 May 2012 00:00:00 GMT Hi Claire, I know how hard it is to see your dog getting chemo especially in the beginning. My dog, Rocky, a standard dachshund, has been getting chemo for nine months now, and has generally done very well.  His pattern is that he gets tired the day of the chemo (and it's a very long drive to the vet oncologist and back) and then is tired or may have loose bowel movements on the third day after chemo.  Otherwise, he has acted pretty normal.  Rocky was always a pretty sedentary dog so the differences are probably less noticable than with Amber.  Rocky is taking Pepsid (10 mg. two times a day) and Metoclopramide 5 mg. 3 times per day. If I manage to get him the Metoclopramide 3 times a day, his appetite is O.K., but if I don't he will pick at his food and then eventually eat it.  Rocky has had an excellent quality of life since August, but I'm afraid things might be starting to get more difficult now.  I felt so badly reading your statement "This is killing me" because I know how hard this is.  This website has been a support to me throughout this process and I hope we can all be there for you.  It's a horrible experience to see your beloved dog with this disease, always do the best that you can and still  see changes.  I can totally relate to just wanting Amber to be normal.  Rocky has acted normal most of the time during the last nine months, but still it is not enough for me and I want real normality back! As far as the mental anguish, some advice I got once keeps me going.  I know that this is eventually fatal, but Rocky does not.  Most of the time he is his happy and affectionate self, and does not have to share the sad feelings that I have thinking about having to part with him sometime.  Love,   Nita   Nita Sun, 20 May 2012 00:00:00 GMT Oh I am so sorry about your step father! What a hard time for you. I am so glad Otis hasn't needed his pain meds! At least Amber hasn't vomitted or decided not to eat all together. When do you go back for more chemo? amberye Sun, 20 May 2012 00:00:00 GMT Hi Claire!! Don't worry, I goof up postings all the time- Otis had his first chemo on Wed-he did real well-no loss of appetite, lethargy or vomitting-but he was tired-lots of naps, and that's ok-chemo causes fatigue-I was more concerned with him getting sick. Maybe you should skip the hikes with Amber for a while...especially the first week or so after chemo when their blood counts drop... I was wondering myself how long until we know if it's working...he has been in less pain- (I haven't had to give him any pain med yet today!!) But who knows?? His Poops are still flat looking-when I see that go away, I'll know it's working. We sure all want our healthy dogs back...this has been a nightmare...and my step-father just passed away yesterday-this cancer; it's just about wiped out my family and now it's got my dog... Chris ps--How's Debbie doing with Peaches?? UTI still there?  cgallo02 Sun, 20 May 2012 00:00:00 GMT On May 20, 2012 4:58 AM LloydR wrote: There is a product called Black Salve (also goes by other names)  that veterinarians can use that is effective against cancer, especially on or near the skin.  If you can't find someone that knows about it, go to doctorsaredangerous.com "" target="_blank" rel="nofollow">http://doctorsaredangerous.com " target="_blank" rel="nofollow">doctorsaredangerous.com and search there.Since April 2011 Black Salve now ban in Australia  as it so good at dissolving cancer tumors it will wipe it out in a day and it only attracts cancer tumor cells leaving the healthy cells be hind But the problem is when the cancer tumor is gone it leaves a big hole an ugly open wound.  but it soon heals up leaving no cancer behind.   rjcrossley Sun, 20 May 2012 00:00:00 GMT and I wish there were a delete option :) How did I post this three times? amberye Sun, 20 May 2012 00:00:00 GMT Amber had her first treatment with mitoxantrone on Thursday morning, seemed very tired the rest of that day and then yesterday she seemed pretty good so we went on two hikes with her and she had tons of fun and seemed to feel very good! Today she is very tired again. Have any of you had that experience with chemo? Everyone keeps telling me that dogs handle chemo very well but I wonder what they mean by that? I want her to be normal, completely normal. Now maybe that's asking for too much but that's what I want. I don't want to pay hundreds and hundreds of dollars to have her feel tired all the time. How will I know it is helping? For those of you who have done chemo and had it help your dog, what did you notice? More energy? A better appetite? She is eating all her food she just doesn't seem very excited about it. This is killing me. Dang, I can not figure out how to use this site! I accidentally posted on the main page instead of here. I can't see where to post a new comment that is not a reply to someone else. Claire amberye Sun, 20 May 2012 00:00:00 GMT Chemo update byamberyeon Sat May 19, 2012 10:54 PM Quote |Reply Amber had her first treatment with mitoxantrone on Thursday morning, seemed very tired the rest of that day and then yesterday she seemed pretty good so we went on two hikes with her and she had tons of fun and seemed to feel very good! Today she is very tired again. Have any of you had that experience with chemo? Everyone keeps telling me that dogs handle chemo very well but I wonder what they mean by that? I want her to be normal, completely normal. Now maybe that's asking for too much but that's what I want. I don't want to pay hundreds and hundreds of dollars to have her feel tired all the time. How will I know it is helping? For those of you who have done chemo and had it help your dog, what did you notice? More energy? A better appetite? She is eating all her food she just doesn't seem very excited about it. This is killing me. Dang, I can not figure out how to use this site! I accidentally posted on the main page instead of here. I can't see where to post a new comment that is not a reply to someone else. Claire amberye Sun, 20 May 2012 00:00:00 GMT Chemo update byamberyeon Sat May 19, 2012 10:54 PM Quote |Reply Amber had her first treatment with mitoxantrone on Thursday morning, seemed very tired the rest of that day and then yesterday she seemed pretty good so we went on two hikes with her and she had tons of fun and seemed to feel very good! Today she is very tired again. Have any of you had that experience with chemo? Everyone keeps telling me that dogs handle chemo very well but I wonder what they mean by that? I want her to be normal, completely normal. Now maybe that's asking for too much but that's what I want. I don't want to pay hundreds and hundreds of dollars to have her feel tired all the time. How will I know it is helping? For those of you who have done chemo and had it help your dog, what did you notice? More energy? A better appetite? She is eating all her food she just doesn't seem very excited about it. This is killing me. Dang, I can not figure out how to use this site! I accidentally posted on the main page instead of here. I can't see where to post a new comment that is not a reply to someone else. Claire amberye Sun, 20 May 2012 00:00:00 GMT Debbie, Gosh, I'm sorry nothing is working! I wish I could help. This whole thing is just a nightmare to me. I want my healthy dog back.  Claire amberye Sun, 20 May 2012 00:00:00 GMT Claire/Chris, Thanks for your advice.  I will ask my vet about the drugs you suggested.  Her culture showed that the bacteria should respond to amoxicillian, but she was on that for 4 weeks and it did nothing.  Last culture showed the same thing.  When the vet tried to perscribe amox again, I got upset and told her that she just got off of it and it didn't work.  I told her that cost was not an issue and I think she needed something stronger or different.  That is when she put her on simplicef.  This doesn't appear to be working either.  This is so frustrating!  What happens if we just cant get rid of the infection?  She has had it now for several months and has been on some type of antibiotic for probably 4 months straight. Debbie MyPeaches Sat, 19 May 2012 00:00:00 GMT Hi Debbie! Sorry you're having a hard time with this-Otis had a bladder infection last week, and it was causing him a lot of distress as well... There are lots of antibiotics; they should be able to tell which one will kill the bug by the culture...I hear doxycycline works well on these patients because it also may have a property that shrinks the tumor...Otis was on Zeniquen-it seemed to work (but it was expensive)-I think after time they start to build a resistance to the drugs.. Maybe try some cranberry tabs?  This may create a more acidic environment in the bladder that the bacteria will not thrive in...ask your vet about this, and ask him/her if you can increase the tramadol to provide some relief for Peaches...best of luck!! Chris cgallo02 Fri, 18 May 2012 00:00:00 GMT Hi Claire! Glad it went well-I was so nervous, but it was like no big deal-I'm just a little nervous for what may come, but he was almost like his old-self today-what a pleasure. Yeah, when this all started it was because of what I thought was diarrha-alot of straining with BMs-then i noticed that some times it came out a little flat-and I thought, somethings in there pressing on his colon; I guessed it was the prostate, which it looks like it's what it is-but, the gland is only mildly enlarged (but unfortunately it contains cancer)-so maybe it is a lymph node or maybe the tumor in the bladder itself-oh, lets hope this all shrinks, for all of these poor dogs-what a lousy disease. I'll keep in touch-fingers crossed!! Chris cgallo02 Fri, 18 May 2012 00:00:00 GMT On May 17, 2012 7:14 PM MyPeaches wrote: I haven't been on this post for a couple of months, but hoping someone can give some advice.  My lab has had this horrible disease for 2 years and recently, it appears that the cancer is progressing pretty fast.  She is on piroxicam, but has recently had a bladder infection that will not clear up.  I frequently have her urine cultured and the last culture shows that here are 2 different types of bacteria growing there.  She has been on Cipro, Amoxicillian and now is on simplicef.  None of these seem to be helping to clear up the infection.  Her oncologist said that the bactieria growing should respond to Amoxicillian, so she went on that for 4 weeks.  Took another culture and it is still infected.  Now she is on simplicef for 4 weeks.  She has been on it for about a week now, and I still see no improvement (still is constantly peeing).  Does anyone know of any other antibiotic that will clear up these persistant bladder infections besides what I have already tried?  Also, anything I can give her for the discomfort?  I have her on Tramadol for pain, but her oncologist says there is nothing else I can give her.  I am desperate to help my little girl get out of this discomfort. DebbieSo the culture must have shown that these bacteria were sensitive to certain antibiotics, the simplicef? When we did a culture of Amber's urine it showed it was sensitive to baytril. I would let your vet know that it doesn't seem to be helping yet, but also maybe it will just take a few more weeks of the simplicef? I am so sorry she seems painful, I don't think we have come to that point yet as Amber doesn't seem to be uncomfortable, but she does pee very often. Especially on a hike when she is running off leash, she squats about every 4 or 5 minutes and half the time, nothing comes out. So she has been pretty normal for 2 years? That is a long time for tcc, right? How old is she? I know that the piroxicam is a strong pain reliever as well as being anti tumor but I don't know what else would work for your dog. Amber is on Deramaxx, which they are using the same way as peroxicam is used but when I first started her on it I asked about peroxicam since that is all I see when I read articles on line about tcc. I did order it and gave her one dose but then the specialist we saw told me to go back to the deramaxx, but I had to make sure not to give the two together and we had to wait a few days in between medications. I wonder if switching to a different NSAID would help her? Lots of luck to you and your dog! Claire amberye Thu, 17 May 2012 00:00:00 GMT I haven't been on this post for a couple of months, but hoping someone can give some advice.  My lab has had this horrible disease for 2 years and recently, it appears that the cancer is progressing pretty fast.  She is on piroxicam, but has recently had a bladder infection that will not clear up.  I frequently have her urine cultured and the last culture shows that here are 2 different types of bacteria growing there.  She has been on Cipro, Amoxicillian and now is on simplicef.  None of these seem to be helping to clear up the infection.  Her oncologist said that the bactieria growing should respond to Amoxicillian, so she went on that for 4 weeks.  Took another culture and it is still infected.  Now she is on simplicef for 4 weeks.  She has been on it for about a week now, and I still see no improvement (still is constantly peeing).  Does anyone know of any other antibiotic that will clear up these persistant bladder infections besides what I have already tried?  Also, anything I can give her for the discomfort?  I have her on Tramadol for pain, but her oncologist says there is nothing else I can give her.  I am desperate to help my little girl get out of this discomfort. Debbie MyPeaches Thu, 17 May 2012 00:00:00 GMT On May 17, 2012 2:41 PM cgallo02 wrote: Hi Claire!!  All went well with first chemo treatment-he is actually acting better than he has been in the last few weeks, although if he gets sick from chemo, it probably won't be for another few days. He's having vinblastine alternating with mitaxatrone-unless either one shows significant improvement along the way, in which case, we'll stick to that one. I was nervous too, but just so happy to get going with something-geeez, I felt as if I had seen 4 doctors in the past month, but nobody was doing anything-c'mon guys-let's go before this spreads anymore!! It's already in his prostate (which I just found out yesterday) which is why this poor guy is having uncomfortable bowel movements-that is also better today (I can't beleive the chemo would work that quick) There was no evidence of any distal mets, which is good, but you know-the x-rays don't see those cells-which is why i beleive chemo is the best shot, as long as it works and doesn't make them so sick-I'll keep you posted, and let me know how you make out...   ChrisHi again Chris! I'm so glad he's feeling better today! Good thoughts that it continues. Our treatment went fine, so far, it was about an hour ago and they gave her the mitoxantrone injection which was very quick. She doesn't seem to be any different. They did say that it may be on the third day or so that I might notice her feeling off. Amber's has also spread, to a lymph node which is pressing on her colon, also causing uncomfortable bowel movements. She doesn't whine or anything but I can tell that it feels different and her poops are long and narrow. Weird. But no other signs of spread anywhere else. I felt the same way, nervous but glad to be doing something. Good luck! Claire amberye Thu, 17 May 2012 00:00:00 GMT Hi Claire!!  All went well with first chemo treatment-he is actually acting better than he has been in the last few weeks, although if he gets sick from chemo, it probably won't be for another few days. He's having vinblastine alternating with mitaxatrone-unless either one shows significant improvement along the way, in which case, we'll stick to that one. I was nervous too, but just so happy to get going with something-geeez, I felt as if I had seen 4 doctors in the past month, but nobody was doing anything-c'mon guys-let's go before this spreads anymore!! It's already in his prostate (which I just found out yesterday) which is why this poor guy is having uncomfortable bowel movements-that is also better today (I can't beleive the chemo would work that quick) There was no evidence of any distal mets, which is good, but you know-the x-rays don't see those cells-which is why i beleive chemo is the best shot, as long as it works and doesn't make them so sick-I'll keep you posted, and let me know how you make out...   Chris cgallo02 Thu, 17 May 2012 00:00:00 GMT On May 13, 2012 2:09 PM cgallo02 wrote: Hi Claire!! I spoke with someone at Purdue who said that it is the needle biopsy that seeds the tumor, not by doing the biopsy with forceps, so I guess you're safe (but I agree, who really knows?) Otis is starting chemo on Wed-I'm nervous, but have lots of hope that this will work.   ChrisThat is what my vet told me too, so that is good. How did Otis do today? I decided to go ahead with the chemo and Amber starts treatments tomorrow. I am nervous! What did Otis have today? Amber will be on Mitoxantrone and Carboplatinum, alternating every other week for six treatments. She is still pretty active and happy so I hope hope hope this doesn't change that. Claire amberye Thu, 17 May 2012 00:00:00 GMT Hi Claire!! I spoke with someone at Purdue who said that it is the needle biopsy that seeds the tumor, not by doing the biopsy with forceps, so I guess you're safe (but I agree, who really knows?) Otis is starting chemo on Wed-I'm nervous, but have lots of hope that this will work.   Chris cgallo02 Sun, 13 May 2012 00:00:00 GMT On May 09, 2012 10:56 PM yamur wrote: On May 09, 2012 9:33 PM Baileysmom97 wrote: I think it's very disappointing that many doctors are not willing to consider the neoplasene.  We've already had one dog whose tumor disappeared and did not seem to suffer any bad effects from the neo.  Hopefully we will get updates from the other dogs that are trying the neoplasene.  If you spend some time reading the case histories on Dr. Fox's website, you'll see that neo is working.  Dr. Fox even used it on himself as a topical and also with an oral dose in ridding himself of a tumor both in and outside of the ear.  Chemo kills everything, although sometimes not even the cancer.  Neoplasene seems to attack the bad cells and leave the healthy ones alone.  It seems it would be worth a try, but call me crazy.My dog yamur was diagnosed yesterday.  I have been researching all of the treatments out there as well as the side effects.  As a biochemist, I have to say there is not enough peer reviewed information about Neoplasene out there.  However, that doesn't mean that I am against it.  Of all of the treatment plans that I have read reviews on, this one is the only one that has several dog owners raving.  I dont believe in chemo for myself, let alone an animal that has no idea what is going on.  I have decided to go with the Neoplasene treatments and will keep others updated with Yamur's progress (hopefully).  I plan on doing this in a more controled, scientific way, in hopes that there is less heresay and more concrete information on this medication.  Yes, please do update us! I am very curious about it, just afraid. Lots of luck to your dog. amberye Thu, 10 May 2012 00:00:00 GMT On May 09, 2012 1:25 AM amberye wrote: I asked the specialist today about the Neoplasene but she said no way would she try it. She said they had one dog who was treated with it at another clinic who almost died from it. I am sure it is different for each dog. I think I am too scared to ask anyone else in town about it. Amber's can't be opperated on since it's in her urethra. I wish we could cut it out of there so bad. Good thoughts for Bailey!I know Zolite works on it for a while.  There been several post on cancer compass about owners who have use had there vet use Zeolite to treat Canine Bladder Cancer rjcrossley Wed, 09 May 2012 00:00:00 GMT On May 09, 2012 9:33 PM Baileysmom97 wrote: I think it's very disappointing that many doctors are not willing to consider the neoplasene.  We've already had one dog whose tumor disappeared and did not seem to suffer any bad effects from the neo.  Hopefully we will get updates from the other dogs that are trying the neoplasene.  If you spend some time reading the case histories on Dr. Fox's website, you'll see that neo is working.  Dr. Fox even used it on himself as a topical and also with an oral dose in ridding himself of a tumor both in and outside of the ear.  Chemo kills everything, although sometimes not even the cancer.  Neoplasene seems to attack the bad cells and leave the healthy ones alone.  It seems it would be worth a try, but call me crazy.My dog yamur was diagnosed yesterday.  I have been researching all of the treatments out there as well as the side effects.  As a biochemist, I have to say there is not enough peer reviewed information about Neoplasene out there.  However, that doesn't mean that I am against it.  Of all of the treatment plans that I have read reviews on, this one is the only one that has several dog owners raving.  I dont believe in chemo for myself, let alone an animal that has no idea what is going on.  I have decided to go with the Neoplasene treatments and will keep others updated with Yamur's progress (hopefully).  I plan on doing this in a more controled, scientific way, in hopes that there is less heresay and more concrete information on this medication.   yamur Wed, 09 May 2012 00:00:00 GMT That is so true! I did a lot of research and chose to treat Siena with neoplasene because it had less side effects and better success than traditional treatments. I went to a highly trained oncologist and all she would do was surgery/radiation/chemo and they had very low success rates. Just as with human doctors, think that natural or plant based remedies are not taught at schools, just pharmaceutical ones. its a shame. Siena has been on it for a month, is tolerating it beautifully and her tumor is shrinking. What more can I ask from a treatment? I was lucky enough to find a vet that has experience using it, and belives in the treatment. She has had remissions in several dogs, which is the best news of all. SienasMom Wed, 09 May 2012 00:00:00 GMT I think it's very disappointing that many doctors are not willing to consider the neoplasene.  We've already had one dog whose tumor disappeared and did not seem to suffer any bad effects from the neo.  Hopefully we will get updates from the other dogs that are trying the neoplasene.  If you spend some time reading the case histories on Dr. Fox's website, you'll see that neo is working.  Dr. Fox even used it on himself as a topical and also with an oral dose in ridding himself of a tumor both in and outside of the ear.  Chemo kills everything, although sometimes not even the cancer.  Neoplasene seems to attack the bad cells and leave the healthy ones alone.  It seems it would be worth a try, but call me crazy. Baileysmom97 Wed, 09 May 2012 00:00:00 GMT On May 09, 2012 2:37 PM Chloebeaglemom wrote: On May 08, 2012 6:43 PM amberye wrote: Hello again everyone. I did talk with the specialist today who really thinks I should go with Deramaxx instead of Piroxicam which is what my vet originally wanted me to use (the deramaxx). She says the only reason piroxicam is prescribed so often is that it was the drug used in the original studies, and that deramaxx is a much better cox 2 inhibitor which is what is needed in the case of tcc. So we are going to start the deramaxx instead. And instead of pepsid, we are going with prilosec. She thinks we should try chemo, both carboplatinum and mitoxantrone, alternating, every three weeks apart. I haven't decided if I will or not. She also did another ultrasound and found that she has an enlarged lymph node which may be pressing on her colon, which may be why I've been seeing long thin poops. For those of you who used chemo on your dog, would you do it again? Did you think it helped in any way? My beagle Cloe was dx on Jan. 2. She had 3 rounds of mitoxantrone, 3 weeks apart. Had no side effects whatsoever. We had ultrasound afte 9 weeks and it showed the tumor to have shrunk slightly. Next ultrasound showed the tumor to be progressing down her urethra. We changed her chemo to Carboplatin. It did cause her to lose her appetite for about 2 weeks. At 3 weeks we did another ultrasound and it showed the tumor to have shrunk some more. She also had an enlarged lymph node from previous ultrasound and it had shrunk also. Probably in the next 2 weeks, we will start the Carboplatin again at a smaller dose plus starting anti nausea med. right away. She also takes Mobic instead of piroxicam. Yes, I am glad we did the chemo. As long as it shows the tumor to be shrinking, we will probably continue. Her oncologist does not do neoplasene. He said it eas basically like giving them acid. Hope things go well for you in whatever choice you make. Susan, Chloe's momThank you so much for your reply Susan! It's good to hear exactly what happened with your dog while on chemo. I don't want to make her upset to her stomach all the time but she could handle a little of it if it shrinks the tumor! One of our problems is that you can't see the urethra very well on an ultrasound and that is where the cancer is growing right now. Yes, the doctor yesterday said neoplasene was basically acid too, and did not trust it. Love to Chole, Claire amberye Wed, 09 May 2012 00:00:00 GMT Amber never had a needle biopsy, just the scope with biopsy forceps inserted into the scope and taken out, all through her urethra, but still, I wonder about things scraping around in there! I know, if you want to know what's wrong you have to have that biopsy so what are you going to do? Claire amberye Wed, 09 May 2012 00:00:00 GMT Penelope is getting vinblastine every other week.  She takes piroxicam everyday.  Next Monday is her next chemo treatment.  She has a CBC every week and chemo every other. penelopesmom Wed, 09 May 2012 00:00:00 GMT On May 08, 2012 3:45 PM penelopesmom wrote: Hi Shelbysmom2, My name is Kim my baby Penelope was diagnosed with TCC in March.  (You feel like your world is crashing down on you and so helpless, it's so sad) She's on piroxicam and has had 2 chemo treatments so far.  The first one did not go so good but the second one went alot better.  After Penelope's first chemo she too urinated clots of blood.  The oncologist said that could be the tumor shedding itself.  I hope so.  We go back to Purdue University in a week for her second ultrasound.  Keep your fingers crossed.  What is Neoplasene?  Thank you for your information.  I will keep you in my thoughts and prayers.  KimHi Penelope's mom!!  What chemo is she getting?  I want to try vinblastine-has anyone here tried this?   cgallo02 Wed, 09 May 2012 00:00:00 GMT On May 08, 2012 6:43 PM amberye wrote: Hello again everyone. I did talk with the specialist today who really thinks I should go with Deramaxx instead of Piroxicam which is what my vet originally wanted me to use (the deramaxx). She says the only reason piroxicam is prescribed so often is that it was the drug used in the original studies, and that deramaxx is a much better cox 2 inhibitor which is what is needed in the case of tcc. So we are going to start the deramaxx instead. And instead of pepsid, we are going with prilosec. She thinks we should try chemo, both carboplatinum and mitoxantrone, alternating, every three weeks apart. I haven't decided if I will or not. She also did another ultrasound and found that she has an enlarged lymph node which may be pressing on her colon, which may be why I've been seeing long thin poops. For those of you who used chemo on your dog, would you do it again? Did you think it helped in any way? My beagle Cloe was dx on Jan. 2. She had 3 rounds of mitoxantrone, 3 weeks apart. Had no side effects whatsoever. We had ultrasound afte 9 weeks and it showed the tumor to have shrunk slightly. Next ultrasound showed the tumor to be progressing down her urethra. We changed her chemo to Carboplatin. It did cause her to lose her appetite for about 2 weeks. At 3 weeks we did another ultrasound and it showed the tumor to have shrunk some more. She also had an enlarged lymph node from previous ultrasound and it had shrunk also. Probably in the next 2 weeks, we will start the Carboplatin again at a smaller dose plus starting anti nausea med. right away. She also takes Mobic instead of piroxicam. Yes, I am glad we did the chemo. As long as it shows the tumor to be shrinking, we will probably continue. Her oncologist does not do neoplasene. He said it eas basically like giving them acid. Hope things go well for you in whatever choice you make. Susan, Chloe's mom Chloebeaglemom Wed, 09 May 2012 00:00:00 GMT Hi Amber and Shelby's Mom!!  Going to keep Neoplasene in mind if conventional treatment fails--I'm a little concerned with the the toxic effects it may have on the liver.  As far as cancer spreading wth biopsies; it looks like it may be the case....My vet who does laser procedures said that there was evidence of this cancer spreading to the incision site (presumably from the laser catheter passing by)-the cells seed along the track made by the needle after a biopsy- perhaps?? Otis had cells removed from a urinary catheter in his bladder, and maybe I need to be concerned that the cells spread down his urethra--nothing I can do about it now--they have to look at the cells to see what they're dealing with, so I guess it can't be avoided.. Chris cgallo02 Wed, 09 May 2012 00:00:00 GMT I asked the specialist today about the Neoplasene but she said no way would she try it. She said they had one dog who was treated with it at another clinic who almost died from it. I am sure it is different for each dog. I think I am too scared to ask anyone else in town about it. Amber's can't be opperated on since it's in her urethra. I wish we could cut it out of there so bad. Good thoughts for Bailey! amberye Wed, 09 May 2012 00:00:00 GMT On May 08, 2012 6:43 PM amberye wrote: Hello again everyone. I did talk with the specialist today who really thinks I should go with Deramaxx instead of Piroxicam which is what my vet originally wanted me to use (the deramaxx). She says the only reason piroxicam is prescribed so often is that it was the drug used in the original studies, and that deramaxx is a much better cox 2 inhibitor which is what is needed in the case of tcc. So we are going to start the deramaxx instead. And instead of pepsid, we are going with prilosec. She thinks we should try chemo, both carboplatinum and mitoxantrone, alternating, every three weeks apart. I haven't decided if I will or not. She also did another ultrasound and found that she has an enlarged lymph node which may be pressing on her colon, which may be why I've been seeing long thin poops. For those of you who used chemo on your dog, would you do it again? Did you think it helped in any way? I think every dog responds differently to the chemo, also depending on which drug.  I tried one round with Bailey and she never felt good until 4 weeks after the first dose and the tumor continued growing despite the chemo.  I had decided to try surgery because the surgeon thought there was a good chance to get the tumor with good margins.  However, once they cut into the bladder they found that the tumor was much closer to the ureters than it seemed on the ultrasound.  A stent was put into each ureter and the tumor was debulked.  What I found very interesting was that my local vet is not willing to pursue the Neoplasene, however, my specialist at UPENN is looking into it.  She was going to speak with Dr. Fox about dosage and I am waiting to hear back.  In the meantime, I have also been trying the Salvestrols but not sure if that has done anything yet.  We have an appointment next week so hopefully we'll be talking about the Neoplasene. From what my doctors have said about chemo that there is a small chance the progression can be stopped, perhaps a one out of three chance.  Bailey had a difficult time with Carboplatin so I didn't want to experiment with different doses.  I have more interest in trying the Neoplasene because most of the dogs that have been on it, don't seem to have any other difficulties. Baileysmom97 Tue, 08 May 2012 00:00:00 GMT Hello again everyone. I did talk with the specialist today who really thinks I should go with Deramaxx instead of Piroxicam which is what my vet originally wanted me to use (the deramaxx). She says the only reason piroxicam is prescribed so often is that it was the drug used in the original studies, and that deramaxx is a much better cox 2 inhibitor which is what is needed in the case of tcc. So we are going to start the deramaxx instead. And instead of pepsid, we are going with prilosec. She thinks we should try chemo, both carboplatinum and mitoxantrone, alternating, every three weeks apart. I haven't decided if I will or not. She also did another ultrasound and found that she has an enlarged lymph node which may be pressing on her colon, which may be why I've been seeing long thin poops. For those of you who used chemo on your dog, would you do it again? Did you think it helped in any way? amberye Tue, 08 May 2012 00:00:00 GMT Thank you penelopesmom Tue, 08 May 2012 00:00:00 GMT Thank you penelopesmom Tue, 08 May 2012 00:00:00 GMT It is an herbal treatment. It can be given orally or infused right into the tumor. Shelby took it orally. You can read about it on the buck mountain botanicals website Since they make it. Most mainstream vets are not willing to try it but a holistic vet may. They vet on the website (dr fox) walked my vet through the process. So far it's been successful for us. I can't say if it would work for anyone else but for us we felt like it was a miracle. Good luck. Shelbysmom2 Tue, 08 May 2012 00:00:00 GMT Hi Shelbysmom2, My name is Kim my baby Penelope was diagnosed with TCC in March.  (You feel like your world is crashing down on you and so helpless, it's so sad) She's on piroxicam and has had 2 chemo treatments so far.  The first one did not go so good but the second one went alot better.  After Penelope's first chemo she too urinated clots of blood.  The oncologist said that could be the tumor shedding itself.  I hope so.  We go back to Purdue University in a week for her second ultrasound.  Keep your fingers crossed.  What is Neoplasene?  Thank you for your information.  I will keep you in my thoughts and prayers.  Kim penelopesmom Tue, 08 May 2012 00:00:00 GMT Shelby had a biopsy and seemed to do fine with it. I never read that it could make the tumor grow although they told me that surgery would make it come back with a vengeance. Also watch her diet she should have no grains and very low carbs as these feed the tumor and a high dose of fish oil per day is good. Shelbysmom2 Tue, 08 May 2012 00:00:00 GMT On May 08, 2012 2:06 AM Shelbysmom2 wrote: My Shelby had success with Neoplasene. You can read my posts under Successful Bladder Cancer Treatment. Basically after 5 months she seems to have passed her tumor in her urine. So far it's still gone. Good luck with whatever treatment you choose. But you might want to check out Neoplasene.We are meeting with a specialist tomorrow and I was going to ask about it. I tend to think she will not recommend it but it sure sounds hopeful! I am almost afraid to try it but what would be the worst it could do, you know? Does anyone feel that their dog got worse after the biopsy? Has anyone read anything about this sort of biopsy causing the cancer cells to spread? Even since I first posted on this forum it seems that Amber is trying to pee more with less and less coming out. My vet mentioned putting in a stent and said it could give her 6 months or more but that I'd have to wait til I notice that she is not able to pass urine. This is torture! She is so innocent. I wish that I could tell her what's going on, but then I wouldn't want her to worry of course. It just breaks my heart to see her running at full speed through the hills like she's always done only to stop every 5 minutes or so to try to pee. She's still so perfect in every other way! This is so completely unfair. amberye Tue, 08 May 2012 00:00:00 GMT My Shelby had success with Neoplasene. You can read my posts under Successful Bladder Cancer Treatment. Basically after 5 months she seems to have passed her tumor in her urine. So far it's still gone. Good luck with whatever treatment you choose. But you might want to check out Neoplasene. Shelbysmom2 Tue, 08 May 2012 00:00:00 GMT Sorry for the bad news-we've all been there; this is a great place to get information-and everybody is real helpful.  My 9 yr old Basset Hound (Otis) was just diagnosed 1.5 weeks ago-It's the same story over and over-the urinary tract infection diagnosis that was later found to be TCC- He's on Piroxicam and Pepcid-we're starting chemo as soon as possible.  Every case and patient is different and what works for some may not work for all-I'll keep you posted on what I do and how it turns out-and I'll keep you in my prayers as well as everyone else going through this miserable time.   Chris cgallo02 Mon, 07 May 2012 00:00:00 GMT Hi Chloe's Mom!!  Otis has been on the piroxicam, and has tolerated it very well-so far.  I'm definitiely going with chemo-just waiting for the vet to get back to me.  I was going to try vinblastine instead of the mitoxitrone-I've read a lot of good things about it, and it sound promising.... Hope the new chemo is working for Chloe-did you try pepcid with the piroxicam?? It may help..ask your vet-I like the fact that the piroxicam may shrink the tumor as well as provide relief.  Otis's tumor is in the neck as well, and I'm watching like a hawk to make sure he is still voiding. I'll let you know how we make out!   Chris     cgallo02 Mon, 07 May 2012 00:00:00 GMT Thank you, Minnie's owner. I am so sorry about Minnie. I guess I just wanted to speak with someone, you know! Someone familiar with all this. I do know that it's not a real cure I am searching for, just temporary peace of mind. Again, thank you so much for your reply. Claire amberye Sat, 05 May 2012 00:00:00 GMT I know you are in shock. Yes, add Pepcid. Good luck, I hoe she feels your love to the end. Karin and Huey karincam1 Sat, 05 May 2012 00:00:00 GMT I will pray for your peace, ahd her easy passing. I am planning a home euthanasia, on his couch, next to me. I live him so much! God bless you as you make decisions for your love. karincam1 Sat, 05 May 2012 00:00:00 GMT I am so sorry to hear of your dog's recent diagnosis. We were diagnosed in March, he is doing well, but peeing less and less. Still full of energy, and eats great. Wish he would just go in his sleep from anything! karincam1 Sat, 05 May 2012 00:00:00 GMT Hi Claire & Amber, My Minnie and I just got this news too, after going through a couple of antibiotic medications that were not working on her urination & bacteria infection issues. Of course once I got the diagnosis, hit the internet and educated myself as much as possible. Had a consultation with an oncologist last week, he pretty much confirmed what I had researched. In Minnie's case, she has large mass in her bladder and the concern is blockage of the urinary track to expel liquid waste. It can either block the kidney flow into the bladder or from the bladder to the outside. Either scenario equates to kidney failure.  http://www.vet.purdue.edu/pcop/CanineUrinaryBladderCancer.pd  is a great article to explain what's going on. I gave Minnie one dose of piroxicam along with pepcid as a preventative to stomach ulcer, as this is a possible side effect of piroxicam. She vomited about 4 times over the next day and a half. The oncologist had me do a blood test to confirm that the kidneys are still functioning to pinpoint the source of the stomach irritation. Kidneys were good so he gave me a prescription for cytotec to help her with the stomach issues. Started the cytotec yesterday and gave her another dose of piroxicam this morning...it's late afternoon and so far things seem good and she is keeping her food down. Unfortunately, a cure is not the goal of the medical community, but rather disease mangement. She is my little baby and my goal at this point is give the time we have left together as much joy as possible. Ok, my eyes are having trouble seeing...got to go now. I wish you both the best, cherrish every moment! MygirlMinnie Sat, 05 May 2012 00:00:00 GMT Hello all, I thought I'd try this forum for some new information. So sad to read of all the dogs struggling with this. Is this where the majority of people discuss tcc? Amber, my 8 year old Vizsla was diagnosed last week Friday with TCC. Her first symptom (and only so far) was just having to pee A LOT. You can't see the blood in it, only under a microscope. She was treated like it was a UTI and then had a culutre done, then more antibiotics and then since it still wasn't gone my vet recommended a scope and a biopsy. It is growing in her urethra. My vet says it's not a place to operate on normally so that is out. He put her on Piroxicam, 1/2 ml once a day. I asked him about using Pepsid since I had read a lot of people use that to help keep the stomach happy and he said it wouldn't hurt so she will start that too. We haven't got the piroxicam in the mail yet. Reading all these comments I want to try EVERYTHING! I know that's silly but I feel so overwhelmed with all the possible "cures" and I want to cure her so badly! What would you all say is the most common treatment and the one most likely to do something? I have been cooking for her, out of the Lew Olsen book, Raw and Natural Nutrition for dogs. She has a chapter about dogs with cancer. For dinner tonight she had a meat pie that I made, using ground beef squished into a baking dish with a few pieces of liver on top and four eggs on top of that, baked. This is a few days worth of meals. Then I add cottage cheese and steamed and pured green veggies (and fish oil, vitamin E, vitamin C, and a teaspoon of powdered eggshell for calcium). I want to get some flax oil and start making the budwig diet but somehow I feel that it is a little silly, I'm sure it's healthy but can it really do all it says it can? Should I try chemo? Or just keep with the piroxicam by itself? For those of you who have used the piroxicam alone have you had any good results? And if using pepsid, do you give it at the same time as the piroxicam or at different times of the day? Thank you for any help. I am so confused and so sad. I just want my healthy dog back! Claire and Amber amberye Sat, 05 May 2012 00:00:00 GMT My Vizsla, Amber, with TCC byamberyeon Fri May 04, 2012 11:05 PM Quote |Reply Hello all, I thought I'd try this forum for some new information. So sad to read of all the dogs struggling with this. Is this where the majority of people discuss tcc? Amber, my 8 year old Vizsla was diagnosed last week Friday with TCC. Her first symptom (and only so far) was just having to pee A LOT. You can't see the blood in it, only under a microscope. She was treated like it was a UTI and then had a culutre done, then more antibiotics and then since it still wasn't gone my vet recommended a scope and a biopsy. It is growing in her urethra. My vet says it's not a place to operate on normally so that is out. He put her on Piroxicam, 1/2 ml once a day. I asked him about using Pepsid since I had read a lot of people use that to help keep the stomach happy and he said it wouldn't hurt so she will start that too. We haven't got the piroxicam in the mail yet. Reading all these comments I want to try EVERYTHING! I know that's silly but I feel so overwhelmed with all the possible "cures" and I want to cure her so badly! What would you all say is the most common treatment and the one most likely to do something? I have been cooking for her, out of the Lew Olsen book, Raw and Natural Nutrition for dogs. She has a chapter about dogs with cancer. For dinner tonight she had a meat pie that I made, using ground beef squished into a baking dish with a few pieces of liver on top and four eggs on top of that, baked. This is a few days worth of meals. Then I add cottage cheese and steamed and pured green veggies (and fish oil, vitamin E, vitamin C, and a teaspoon of powdered eggshell for calcium). I want to get some flax oil and start making the budwig diet but somehow I feel that it is a little silly, I'm sure it's healthy but can it really do all it says it can? Should I try chemo? Or just keep with the piroxicam by itself? For those of you who have used the piroxicam alone have you had any good results? And if using pepsid, do you give it at the same time as the piroxicam or at different times of the day? Thank you for any help. I am so confused and so sad. I just want my healthy dog back! Claire and Amber amberye Sat, 05 May 2012 00:00:00 GMT On May 03, 2012 3:22 PM Aragosta wrote: Our girl Lola has been in the fight for about a year and a half. To make a long story short... it has metastasized.  The CT scan showed dozens of growths in her thorax and thyroids.  The doctor said she has two or three weeks left. The immediate issue is that her urethra has gotten worse.  She now has great difficulty clearing her bladder, having to urinate a trickle every 15 minutes and having accidents all over. In the past week she has stopped eating her favorite foods... bread, peanut butter... she even turns her nose up at chicken. I considered a stent... but for a handful of weeks that are likely to be ugly regardless... why?  The blessing is that it was a great 18 months.  She did not even know she was sick all this time, and bounced back from both surgeries as if they did not even happen.    The problem now is that for my Lola, who still smiles and wags her tail every time every time she sees me, I have to decide whether it is going to be tomorrow, or the day after, or the day after that...    My heart goes out to you. You are entering into....the final act of complete love of our pets.  You fought the hard fight and now you will love Lola enough to release her from any pain that will befall her in the end. My prayers are with you and yours....and Lola....may she run with all the rest of our beloved pets that have succumbed to this awful disease....and wait for you at theRainbowBridge.  You'll recognize her...... by her smile! God Bless. ChicasMom, Lynn ChicasMom Fri, 04 May 2012 00:00:00 GMT I'm so sorry for Lola and you. Making these decisions is daunting and letting go of a loved one is so painful. For all the sadness, there is also a beauty and integrity of accompanying our furry friends as far down the old dirt road to the sky that we can. A  friend of mine has a vet that will come to your house in cases like these. I think that's a nice idea, rather than having their last moments be in a doctors office. I wish you strength and love as you navigate this. jenn SienasMom Fri, 04 May 2012 00:00:00 GMT On May 02, 2012 2:51 PM cgallo02 wrote: thanks! and I'm sorry for your baby--will return prayers....making some treatment choices-I'd appreciate opinions on chemo-not sure which one to try.   ChrisMy beagle Chloe aw dx on Jan. 2 We did 3 rounds of chemo with the drug mitoxantrone. She was also on meloxicam instead of piroxicam. (supposed to be easier on the stomach). 3 rounds took 9 weeks , then we did another ultrasound and it showed the tumor (in the trigone area) had shrunk slightly. With this chemo, she had absolutely no side effects. We continued with the chemo and did another ultasound 6 weeks later and it showed the tumor to be growing farther down her urethra. We changed the chemo to Carboplatin and have only had the 1 treatment 2 weeks ago. She has had lots of side effects from this one. Not eating anything but grass. Have just in the past two days I've been able to get her to eat some cooked lean beef. We Have an appt. on May 9th to have another ultrasound to see if this new chemo has worked. If it shows shrinkage, we will try it again at a smaller dose. If it is still growing we will probably try using piroxicam if we can get her stomach straightened out. Our oncologist says the neoplasene is basically an acid and does not recommend it. This is a terrible disease and hard to watch the straining to pee. She still does not go out that often but when she does, it is constant straining. Until this last chemo, you would not have known anything was wrong with her unless you saw her peeing. She had even gained weight with the chicken and veg. I was giving her. Best of luck in whatever decision you make. Susan, Chloe's mom Chloebeaglemom Fri, 04 May 2012 00:00:00 GMT  My little girl, Annie lived for 16 mos. passed dx although she was given 1 year. Before Annie died, my husband met a vet at the airport and he asked her in her opinion, when is the right time?  She told him that too many people wait way too long and she sees dogs that have suffered too much.  Another forum member wrote if the dog has lost quality of life and was no longer interested in doing things that had brought them happiness.  Annie was still alert, still tail wagging.  To this day I thought she had more time.  But the vet reminded us that she wasn't hardly eating, she was so tired from waking up every 2 hours to go outside and getting weaker.  He felt her bladder and said it was hard as a rock because of the tumor.  Even though she wanted to leave the vet and was pulling on her leash to go home, I knew home would be the same battle-trying to get some food in her, giving her subQs by needles (which she hated) and her being totally exhausted from no sleep.   It was so difficult and it brings tears just writing this and reliving it.  My heart goes out to you. Judi anniebananie Thu, 03 May 2012 00:00:00 GMT My heart goes out to you.  I agree-- a stent for a matter of a few weeks doesn't seem worth it.  Please know that I'll be thinking of you as you face this difficult time.  Words just don't suffice.. but know that we on this site are with you in spirit. Nita   Nita Thu, 03 May 2012 00:00:00 GMT I am so sorry.  We are all in this boat.  Iloverio Thu, 03 May 2012 00:00:00 GMT Our girl Lola has been in the fight for about a year and a half. To make a long story short... it has metastasized.  The CT scan showed dozens of growths in her thorax and thyroids.  The doctor said she has two or three weeks left. The immediate issue is that her urethra has gotten worse.  She now has great difficulty clearing her bladder, having to urinate a trickle every 15 minutes and having accidents all over. In the past week she has stopped eating her favorite foods... bread, peanut butter... she even turns her nose up at chicken. I considered a stent... but for a handful of weeks that are likely to be ugly regardless... why?  The blessing is that it was a great 18 months.  She did not even know she was sick all this time, and bounced back from both surgeries as if they did not even happen.    The problem now is that for my Lola, who still smiles and wags her tail every time every time she sees me, I have to decide whether it is going to be tomorrow, or the day after, or the day after that...    Aragosta Thu, 03 May 2012 00:00:00 GMT On May 02, 2012 2:16 AM lebohead wrote: Hello Siennas Mom, My doggie has been on neo for a week and a half. My vet wants her on piroxicam as well. (I know its a big no-no) Is your doggie on any thing else? Im tempted to take her of it the piroxicam but also afraid too. Also is your doggie on an antibiotic? Also how big is siena? What is the neo dose you have her on? Sorry for all the questions, Just searching for help, Thanks, RosiesmomI decided to follow the protocal and not have her on any other medicines, besides the neoplasene. Since the drugs work differently, I think that combining them may lessen the overall effectiveness of either treatment. She is 54 pounds and gets 1cc of neo twice a day, after meals. She could go to a higher dosage, but since she appears to be responding to the treatment and tolerating it well, the vet decided to leave her at this level for now. She's not on antibiotics. I do give her a 1000 mg fish oil pill with each meal, and vitamins occasionally. I also feed her homecooked meat and cooked veggies with a low glycemic index, no kibble. Its a pain some days, but diet is so important to inhibit the growth of the tumor. Pick a treatment that you trust and go with it! SienasMom Wed, 02 May 2012 00:00:00 GMT On May 02, 2012 2:16 AM lebohead wrote: Hello Siennas Mom, My doggie has been on neo for a week and a half. My vet wants her on piroxicam as well. (I know its a big no-no) Is your doggie on any thing else? Im tempted to take her of it the piroxicam but also afraid too. Also is your doggie on an antibiotic? Also how big is siena? What is the neo dose you have her on? Sorry for all the questions, Just searching for help, Thanks, RosiesmomI decided to follow the protocal and not have her on any other medicines, besides the neoplasene. Since the drugs work differently, I think that combining them may lessen the overall effectiveness of either treatment. She is 54 pounds and gets 1cc of neo twice a day, after meals. She could go to a higher dosage, but since she appears to be responding to the treatment and tolerating it well, the vet decided to leave her at this level for now. She's not on antibiotics. I do give her a 1000 mg fish oil pill with each meal, and vitamins occasionally. I also feed her homecooked meat and cooked veggies with a low glycemic index, no kibble. Its a pain some days, but diet is so important to inhibit the growth of the tumor. Pick a treatment that you trust and go with it! SienasMom Wed, 02 May 2012 00:00:00 GMT On May 02, 2012 2:16 AM lebohead wrote: Hello Siennas Mom, My doggie has been on neo for a week and a half. My vet wants her on piroxicam as well. (I know its a big no-no) Is your doggie on any thing else? Im tempted to take her of it the piroxicam but also afraid too. Also is your doggie on an antibiotic? Also how big is siena? What is the neo dose you have her on? Sorry for all the questions, Just searching for help, Thanks, RosiesmomI decided to follow the protocol and not have her on any other medicines. Since the drugs work differently, I think they may lessen the overall effectiveness of the treatment.  I do have her on 2000 mg of fish oil and I give her some vitamins occasionally. I also feed her home cooked meat and veggies, no kibble. Its a pain some days, but diet is important to keep the cancer from growing. Keep us posted on how you proceed, and good luck.  SienasMom Wed, 02 May 2012 00:00:00 GMT thanks! and I'm sorry for your baby--will return prayers....making some treatment choices-I'd appreciate opinions on chemo-not sure which one to try.   Chris cgallo02 Wed, 02 May 2012 00:00:00 GMT I'm sorry to hear about your dog.  My 10 1/2 year old pug penelope was diagnosed in March with TCC.  It's so scary to hear but helpful to know there are people out there going thru the same thing.  I will say a prayer for your baby. penelopesmom Wed, 02 May 2012 00:00:00 GMT Hello Siennas Mom, My doggie has been on neo for a week and a half. My vet wants her on piroxicam as well. (I know its a big no-no) Is your doggie on any thing else? Im tempted to take her of it the piroxicam but also afraid too. Also is your doggie on an antibiotic? Also how big is siena? What is the neo dose you have her on? Sorry for all the questions, Just searching for help, Thanks, Rosiesmom lebohead Wed, 02 May 2012 00:00:00 GMT Just a quick update on Siena, she had her first checkup after beginning oral neoplasene three weeks ago. The vet did an ultrasound and believes the tumor is shrinking slightly! (The tumor size changes as the bladder walls expand/contract with the bladder is full/empty, so I'm trying to take her with a full bladder all the time.) She has tolerated the medicine very well. I mix it with cottage cheese after her meals and she eats it with no problem. She has also had no side effects from the treatment. I'm really pleased with her progress and truly appreciate the info that everyone shares on here. It really helped me choose a treatment path that I felt good about. SienasMom Mon, 30 Apr 2012 00:00:00 GMT So sad to hear about Charlie, touching tribute and thanks for sharing your experience. Through it you've helped others and thats a great tribute in itself. poppy06 Mon, 30 Apr 2012 00:00:00 GMT Suzanne, I am so sorry to hear about Charlie. What a beautiful tribute to Charlie.  My heart goes out to you and yours. As painful as it is to write to let us know, please know, that it is also painful for us to hear yet another one of our loving pets is gone.  We feel your pain like it is our own...because it WILL be...sooner...later...yes it will be our own. ChicasMom, Lynn   ChicasMom Mon, 30 Apr 2012 00:00:00 GMT Hi everone! I'm new to this board-my 9 year old Bassett Hound was just diagnosed with TCC, so I'm off on this painful journey-happy to see so much information posted, and sad to share in everyone's pain. I'll be sure to post and information I can obtain.   Chris cgallo02 Sun, 29 Apr 2012 00:00:00 GMT Very sad to hear about Charlie.  None of us are ever ready for when that day comes.  As Shelby's mom said, we do appreciate the shared stories.  Hopefully through sharing our fights, we can beat this tcc! Just to update Bailey's story, I spoke with both my local vet and her Dr. in Philadelphia about the neoplasene.  My local vet thinks it will be too much of an irritant, however, her specialist will atleast be speaking with Dr. Fox to consider it.  Baileysmom97 Sat, 28 Apr 2012 00:00:00 GMT So sorry for your loss but over 2 years seems like a blessing with TCC. sorry for your pain. He sounds like a wonderful pet. I hate that you had to go through this but try to focus on the wonderful times you had. Thanks for sharing your story from beginning to end. Those of us who are still fighting appreciate it. I hope you will find the strength to love another dog one day as it sounds like you are a great owner. Best of luck to you. Shelbysmom2 Fri, 27 Apr 2012 00:00:00 GMT Dear Charliesmom, I'm so sorry to hear about the Charlie.  You were both lucky to have each other. My thoughts are with you. {{{ Hugs }}} MomToBella Fri, 27 Apr 2012 00:00:00 GMT Thank you so much, Shelby's mom. We definitely did give TCC a run for its money--two surgeries, chemo and, at the end, sub q fluids and about 30 pills a day. My Charlie was a total rock star in every way--as long as he was willing to fight, we were determined to give him the tools. I hope even a couple of brave dogs (and dog lovers) were helped by the information I shared here. Best of luck to you and all the other dog moms and dads just trying to eke out a bit more time with their babies. I hope you get all the time Charlie got and more. Suzanne  charliesmom Fri, 27 Apr 2012 00:00:00 GMT Thanks so much, Judi--you and I have been around this board a long time. I keep meaning to look up Sue's e-mail to let her know--we had a couple of exchanges off the message board. We really had a pretty good two and a half years--most of the time, Charlie felt good and acted happy. The decline in the last few weeks was pretty rapid. In the end, the bladder tumor metastasized to his brain stem and there was nothing more we could do. Even the amazing Dr. Cerf was powerless against that. Michael and I are truly heartbroken, but we were fortunate to live so close to Ridgewood and get the care that extended Charlie's life well past the TCC average. Our vet in Hoboken was amazing too--Charlie had a fantastic team and lots of love. But he was also a tough little guy who refused to give up until the very end. Warmly, Suzanne   charliesmom Fri, 27 Apr 2012 00:00:00 GMT So sorry for your loss but over 2 years seems like a blessing with TCC. sorry for your pain. He sounds like a wonderful pet. I hate that you had to go through this but try to focus on the wonderful times you had. Thanks for sharing your story from beginning to end. Those of us who are still fighting appreciate it. I hope you will find the strength to love another dog one day as it sounds like you are a great owner. Best of luck to you. Shelbysmom2 Fri, 27 Apr 2012 00:00:00 GMT Suzanne, I have been folllowing you since you came on the forum back in early 2010.  Willie and Sue and me and Annie were regular posters.  Even though you hadn't posted, I was hoping that meant good news.  Charlie was such a sweet Westie and the bravest dog.  My heart goes out to you.  I know your pain.  Find comfort in that you did all you could and Charlie felt your love.  Judi anniebananie Fri, 27 Apr 2012 00:00:00 GMT                                              Charlie May 13, 2000 – April 26, 2012  A beautiful dog inside and out, Charlie had a brave heart, an old souland an iron will. He exceeded the life expectancy for dogs withTransitional Cell Carcinoma by almost two years with a cheerful outlook,a fighting spirit and a patient acceptance of being poked, proddedand medicated (in addition to a crack medical team). A peaceful, playful and loving companion to us, Charliewas a tolerant friend to puppies and small children and an enemy of squirrels, skateboards and big mean dogs till the very end. We haven't been on the message board in a while though I have posted many times in the two-plus years we have been dealing with TCC and told of our amazing work with Dr. Dean Cerf at Ridgewood Veterinary Hospital. I'm sad Charlie didn't make it to his 12th birthday or his official two and a half years since Dx, but we were very fortunate to have so much time together and most of it was very, very good.   In the end, the TCC tumor metastasized to his brain stem and he started have seizures. That made the decision to let him go very easy. Every vet and tech at our usual vet hospital paid tribute to Charlie's fighting spirit and the amazing number of times he bounced back from the very brink. No dog ever battled harder.   We are heartbroken and devastated, but there have been valuable lessons for us in this experience--I don't know if I would ever be able to face illness and the end with Charlie's grace, calm and stoicism but he was a model of bravery.   As painful as this is to write, I wanted to come on and let you all know Charlie had passed. Over the past two-plus years, dogs whose stories we followed just ended without explanation and I wanted to provide our friends and followers on the board with some closure, as well as pay tribute to the best Westie ever, in every way.   Thank you all for your support and stories over the years.  charliesmom Fri, 27 Apr 2012 00:00:00 GMT For anyone interested in Neoplasene, please see my post under Successful Bladder Cancer Treatment.  Good luck to you all and prayers for success.   Shelbysmom2 Fri, 27 Apr 2012 00:00:00 GMT Shes on mitoxantrone i think. The 2nd round was really rough on her and she wasnt herself for about a week and a half, most of this time only being able to get her to eat raw chicken and cheese and she spent alot of time outside eating grass too. The last round they gave her a long last anti-nausea injection and this delayed her nausea for about a week and then she only had a couple of days where I had to go back with conning her to eat with chicken and cheese. Understand how you feel with it, I was feeling very guilty with how crook she was, but seeing how much it has shrunk made me feel ok with putting her through it, if it hadnt shrunk much i'm not sure what i would of done or if i would of continued. Hope Chloe's ultrasound shows a better result this time. poppy06 Thu, 26 Apr 2012 00:00:00 GMT On Apr 23, 2012 9:15 AM poppy06 wrote: Hi guys, I agree with the sentiments around toxins and did a lot of research on this when Poppy was first diagnosed.  The key things I took out of it were reducing exposure to chemicals - Switched all cleaning products to natural ones, got rid of the automatic fly spray and used only bottled water for her drinking water.  Carbs and sugar feed cancer, so switched to fresh meat and veges, with a mix of cottage cheese and flax oil, and high dosage vitamin c has an effect on killing cancer cells, so based on Poppy's size of about 9lbs have been giving her about 600mg each day. Poppy has been on piroxicam daily since the end of February and has had 3 rounds of chemo, all symptoms of her cancer disappeared, however between rounds 2 and 3 of the chemo, she started becoming incontinent in her sleep (this seems to have stopped now).  Today she had an ultrasound, which showed at the largest point the cancer had shrunk to 0.27cm, after an initial 1.57cm at diagnosis.  At diagnosis the cancer was in the neck of the bladder and threatening to block her ureter at any time.  So am very happy with her progress, we've had some tough bouts with the chemo, but am so happy with how she is today.  Hope the info i've listed above is helpful to someone, I have no idea what has attributed the most to her treatment, but am just glad something has. What kind of chemo is Poppy on? Mitoxantrone or Carboplatin ? Chloe my beagle did well in the beginning with mitoxantrone but last weeks ultrasound showed the tumor to be growing down her urethra. So we changed to the Carboplatin and she's had a rough week. Not wanting to eat anything but grass. Today I have been able to get some cooked lean beef and chicken in her. We are doing another ultasound on May 9th to see if this chemo is working. Terrible disease to deal with. Glad Poppy has made it this long. Chloebeaglemom Thu, 26 Apr 2012 00:00:00 GMT Hi Pam, Sorry i missed your post asking about the difference raw food made, however i wouldnt of been able to tell you at that point. I do think that it's made a sifference, especially looking at how her tumour has shrunk more than her vets were expecting. We are in new zealand and the hollistic information is hard to come by so I really had to dig around online and what i ended up doing food wise and elimination of toxins was really just a combination of stuff i found, the vets here seem to be more focused on medical, so i've just been telling them what i've been doing, they havent been able to give me much information on it. Poppys worst symptom from the before diagnosis was bleeding and it was what made me take her to the vet. There was a large amount in her wee one day and i noticed blood dripping from her. Since she started the chemo, shes only bled three times, each of them were straight after the chemo sessions. All her symptoms are now gone, and we still have two chemo sessions to go to knock the last of it on it's head hopefully. At diagnosis they gave her prognosis as 365 days with the chemo, this is currently revised to 450, which i would put the increased time on the food and toxin elimination. I really at the end just wanted to be able to look back and say i had done everything i could. I haven't really noticed any other effects on her from the vit c, am pleased that you are though. When will you be having updates on ultrasound to see what effect everything you are doing has had? Esther poppy06 Wed, 25 Apr 2012 00:00:00 GMT Poppy's Mom So glad to hear what you have been doing has helped.  I had put a query out asking if anyone saw a difference once they changed from commercial to homemade meals and no one replied.  We are feeding basically the same as you with tons of suppliments.  Yesterday I ordered something called CurOst from a vet in N. Carolina and we will be able to eliminate a few of the suppliments - Vit c, e, turmeric and flaxseed as they are all part of this powdered formula.  From what I have read on his treatment for horses and dogs it has been very helpful and tonight I found another site that is also recommending it for us as part of a juicer. This vet Dr. Schell used it himself in his own quest for a more holistic approach to his own bladder cancer.  My local vet had given me info on using Vit C as an IV solution but so far can not come up with a supplier for it.  I went to the pharmacy and they told me it has to be a special facility that can handle it - possibly a compounding one but I haven't checked any further.  Dr. Andrew Saul from Food Matters HIGHLY recommends the IV for people with cancer. We are currently giving our little girl who is 16 lbs 500mg in the morning and again at night.  She had had anal gland issues her whole life and just after the first week - no more!  Her depressed mood lifted and she was more like her old self just from the Vit. C!  Once the anitbiotics were started (tons of bacteria in her urine) she has been less peppy and by night will hardly move.  Mila started out with leaking but not real incontinence like our other schnauzer girl - Maggie.  She (Maggie) was on DES (along with Bladder Strength) until we noticed she was gaining weight very rapidly when they upted her dose this last time (due to the excessive licking).   Found a product in the health food store called Acti-Pet for Canine Continence and she has reduced her licking and leaking by about 95% much better results than the DES ever gave.  I feel that the Acti-Pet has been helping Mila - the licking was her most prominent symptom along with chronic UTI's until all the bleeding started.  Did your Poppy have the vulva bleeding too? Glad you are having success - good luck to you.    Mila01 Wed, 25 Apr 2012 00:00:00 GMT Hi guys, I agree with the sentiments around toxins and did a lot of research on this when Poppy was first diagnosed.  The key things I took out of it were reducing exposure to chemicals - Switched all cleaning products to natural ones, got rid of the automatic fly spray and used only bottled water for her drinking water.  Carbs and sugar feed cancer, so switched to fresh meat and veges, with a mix of cottage cheese and flax oil, and high dosage vitamin c has an effect on killing cancer cells, so based on Poppy's size of about 9lbs have been giving her about 600mg each day. Poppy has been on piroxicam daily since the end of February and has had 3 rounds of chemo, all symptoms of her cancer disappeared, however between rounds 2 and 3 of the chemo, she started becoming incontinent in her sleep (this seems to have stopped now).  Today she had an ultrasound, which showed at the largest point the cancer had shrunk to 0.27cm, after an initial 1.57cm at diagnosis.  At diagnosis the cancer was in the neck of the bladder and threatening to block her ureter at any time.  So am very happy with her progress, we've had some tough bouts with the chemo, but am so happy with how she is today.  Hope the info i've listed above is helpful to someone, I have no idea what has attributed the most to her treatment, but am just glad something has. poppy06 Mon, 23 Apr 2012 00:00:00 GMT Hello Lynn   (Mom to Mila01)  Both of my schnauzers were exposed to the China issue with Bestrom chicken strips and were very sick but survived.  I got no response from the letters I wrote to Walmart (the only supplier of these) nor to Bestrom in China.  I too have walked my 2 babies every day twice a day for their entire 10.5 years - even during blizzards they would wait for their cherised walk!  And due to food allergy issues have been on Hills Z/D for most of their lives - that is not what I call premium food just premium pricing.  Since Mila's diagnoses I have been making all her food and supplimenting with vitamins according to Dr. Pitcairn's book.  She has been acting more like her old self for most of this week and I have to believe it is because of the fresh veggies, fresh meat , no carbs and organic whenever possible and suppliments.  I just ordered a product that helps with cancer and inflammation called CurOST and have had many correspondences with Dr. Tom Schell who runs a practice for small animals and equine in North Carolina.  He also suggested a Chinese herb called Shao Fu Zhu Yu Wan that he has been using for his cancer patients with success and we have started Mila on that.  This info was given to me by my vet as a possible alternative. Chemo and radiation are out of the question for it's side effects and efficacy.  We take one day at a time and are optimistic at this time. Wishing all of you the best in what ever course you take - Pam Mila01 Mon, 23 Apr 2012 00:00:00 GMT On Apr 21, 2012 1:38 PM ChicasMom wrote: Hi Brenda (MomToBella), Good post...and...wonderful Mom to Bella in her time fighting this horrible disease TCC. Let's not forget the "China connection" to the foods that we have fed out pets.  A lot of the premium foods were made with ingredients from China (melamine).  I wonder how many of our furbabies ingested this tainted food and we were not aware of it's toxicity.  When the recalls were sounded we just stopped using the offending product and chose another premium food that was not on the list. Only one of the foods that Chica ate was on the recall, but I still.....wonder. When you do the very best you can...before, during and after TCC...there is no second guessing "could we could have done more?". "I don't blame myself for Bella getting bladder cancer.", this statement in itself shows that you did your "very best" to take care of Bella.  You remain healthy in mind, body and spirit AND remember the good times with Bella. It's good to hear from you...I wish you peace. ChicasMom, Lynn PS  Chica is still chugging along, turned 9 in April and we are heading to 3 years post DX in July.  My own "energizer bunny". Wish us luck.Lynn, where was Chica's tumor located? Chloe's is in the trigone area and I don' see her making it to 3 yrs. You are blessed to have had her this long. There has been a big change just in the past 3 weeks. I may of asked you this before, but what other supplements are you giving her? Right now I'm just having a hard time getting her to eat. Thanks for your help and support. Susan Chloe's mom Chloebeaglemom Sun, 22 Apr 2012 00:00:00 GMT Hi Brenda (MomToBella), Good post...and...wonderful Mom to Bella in her time fighting this horrible disease TCC. Let's not forget the "China connection" to the foods that we have fed out pets.  A lot of the premium foods were made with ingredients from China (melamine).  I wonder how many of our furbabies ingested this tainted food and we were not aware of it's toxicity.  When the recalls were sounded we just stopped using the offending product and chose another premium food that was not on the list. Only one of the foods that Chica ate was on the recall, but I still.....wonder. When you do the very best you can...before, during and after TCC...there is no second guessing "could we could have done more?". "I don't blame myself for Bella getting bladder cancer.", this statement in itself shows that you did your "very best" to take care of Bella.  You remain healthy in mind, body and spirit AND remember the good times with Bella. It's good to hear from you...I wish you peace. ChicasMom, Lynn PS  Chica is still chugging along, turned 9 in April and we are heading to 3 years post DX in July.  My own "energizer bunny". Wish us luck. ChicasMom Sat, 21 Apr 2012 00:00:00 GMT On Apr 20, 2012 1:48 AM Mila01 wrote: On Apr 18, 2012 5:15 PM Baileysmom97 wrote: Thank you all for the support.  My little girl bounced right back and was up and about a few hours after the surgery.  They are letting me bring her home today.  I may try upping her dosage of the salvestrols or possibly consider the oral neoplasene.  Just don't want to let this TCC win out in the end! To top it all off, my friend's fiance just got diagnosed with colon cancer at 41 years old.  We've got to find a cure!I may come off sounding crude but don't you think we already know what it is?  It's in the food in the air on the ground - pesticides, herbicides, insecticides, nitrates, nitrities, pop, candy,convenience foods, microwave NONE OF IT IS NATURAL.  There is so much going on between the FDA and drug companies - look upwww.burzynskimovie.com "" target="_blank" rel="nofollow">http://upwww.burzynskimovie.com " target="_blank" rel="nofollow">upwww.burzynskimovie.com  and shutting down people who are actually having success at finding answers to this disease!  Watch Fork over Knives, Food Matters, Food Inc.  All are wonderful examples of how we are being killed by the companies providing the FOOD WE EAT. Read Dr. Neal Barnard's book "Foods that Fight Pain".  And it all affects our little friends - it goes in their mouths TOO!  GO ORGANIC Stop eating meat and processed foods and stop applying chemicals to yards.  Our best friends are breathing in, laying, sitting and running on these yards then licking their feet and fur to clean themselves -  ingesting the harmful products that are hurting them.  Fight to keep out Nuclear Power Plants - it all matters and even if you do just one of these it will help.  Love to all the little animals and their parents who are having to endure the toughest times of their lives. It hurts to realize how much I contributed to my little girls early decline and all to make my yard look nice and GREEN.  It's most likely the reason I had endometrial cancer  I've been using this stuff for years and may even be responsible for why both of my 2 children are bipolar! CHEMICALS CHEMICALS CHEMICALS. Bless all of you for loving your best friends and not giving up.  I have gone over WHY many time in my head. WHY did our Bella get bladder cancer? Here is what I came up with: 1) Genetics.  She was a Sheltie (one of the five breeds that are more predisposed to the disease. 2) Chemicals.  Exposure to lawn chemicals.  Here in TN, they slather the lawns with all sorts of chemicals and I walked Bella twice a day everyday for all of her twelve years.  Ironically, we did not put any chemicals in our backyard, but her exposure to other lawns was probably enough. 3) Diet.  I always fed Bella premium dog food.   Only the best.  But was that enough?  Would humans do well if we only ate kibbles designed specifically for us?  I think we can do better on the diet front.  If we ever get another dog, I'll be doing more research on how I can give my dog even better nutrition, including fresh foods. I don't blame myself for Bella getting bladder cancer.  I'm just reflecting on what I know now.  Bella had a wonderful life with us.  She probably lived longer than she would have with anyone else.  With the care she got from us, she should have lived well beyond the average life expectancy of a Sheltie. MomToBella Sat, 21 Apr 2012 00:00:00 GMT I met a woman at UPENN who had two dogs, one with bladder cancer who managed to live 5 years only being on an anti-inflammatory and the other dog went blind in one day.  Some kind of rare disease (only 100 cases in entire US).  They did some research and do not drink any tap water.  Supposedly New York, Delaware, Maryland, Pennsylvania and New Jersey have the highest rate of oral and bladder cancers. It's definitely all the garbage chemicals that are in the food as well.  I have fed Bailey regular fresh food but she loves Dingo bones and Pupperoni sticks and my guess is it's probably those. Baileysmom97 Fri, 20 Apr 2012 00:00:00 GMT You are right.  We have met the enemy, and he is us. Iloverio Fri, 20 Apr 2012 00:00:00 GMT On Apr 18, 2012 5:15 PM Baileysmom97 wrote: Thank you all for the support.  My little girl bounced right back and was up and about a few hours after the surgery.  They are letting me bring her home today.  I may try upping her dosage of the salvestrols or possibly consider the oral neoplasene.  Just don't want to let this TCC win out in the end! To top it all off, my friend's fiance just got diagnosed with colon cancer at 41 years old.  We've got to find a cure!I may come off sounding crude but don't you think we already know what it is?  It's in the food in the air on the ground - pesticides, herbicides, insecticides, nitrates, nitrities, pop, candy,convenience foods, microwave NONE OF IT IS NATURAL.  There is so much going on between the FDA and drug companies - look upwww.burzynskimovie.com  and shutting down people who are actually having success at finding answers to this disease!  Watch Fork over Knives, Food Matters, Food Inc.  All are wonderful examples of how we are being killed by the companies providing the FOOD WE EAT. Read Dr. Neal Barnard's book "Foods that Fight Pain".  And it all affects our little friends - it goes in their mouths TOO!  GO ORGANIC Stop eating meat and processed foods and stop applying chemicals to yards.  Our best friends are breathing in, laying, sitting and running on these yards then licking their feet and fur to clean themselves -  ingesting the harmful products that are hurting them.  Fight to keep out Nuclear Power Plants - it all matters and even if you do just one of these it will help.  Love to all the little animals and their parents who are having to endure the toughest times of their lives. It hurts to realize how much I contributed to my little girls early decline and all to make my yard look nice and GREEN.  It's most likely the reason I had endometrial cancer  I've been using this stuff for years and may even be responsible for why both of my 2 children are bipolar! CHEMICALS CHEMICALS CHEMICALS. Bless all of you for loving your best friends and not giving up.   Mila01 Fri, 20 Apr 2012 00:00:00 GMT Bailey came home yesterday.  Overall she's doing pretty well...she just has a constant urge to go and nothing really coming out other than a few drops of blood.  The doctor has said that it should get a little better each day, but could last as long as a week.  I try to keep her medicated for the pain and that knocks her out for awhile and lets her rest. The doctor also had to put her on blood pressure medicine because her heart wall has started to thicken because her pressure has been pretty high, around 200. I appreciate the support and good wishes all of you have given.  I am determined to still fight this disease! Baileysmom97 Thu, 19 Apr 2012 00:00:00 GMT As far as the ultrasound goes, you might want to ask if you can watch. I've insisted on that before, and the vet was very accomodating. That also ensures that you'll get Winsley in and out quicker.  Just a thought... good luck. SienasMom Wed, 18 Apr 2012 00:00:00 GMT Glad Bailey is going home.  Hope the best for you both.  Chloe had an appt today for another round of chemo but after the ultrasound,  it showed the tumor to be progressing down her uretha.  We stared another kind of chemo and will know in 3 weeks if it is helping.  The Dr. said if could be weeks or even months before she is completely blocked.  At that point we will probably do a cystotomy.  It is a tube that runs from her bladder to her stomach wall.  I will then empty it 3 or 4 times a day with a syringe.  As long as she is not in any pain, I will continue to do this.  She is just so fat and healthy looking, you would not know anything was wrong unless you watched her pee.  This is such a horrible disease for our loving companions to go thru and such stress for us in trying to do all we can to save them.  Please know you are in my thoughts along with all the other on this message board that are experiencing the same thing.    Chloebeaglemom Wed, 18 Apr 2012 00:00:00 GMT Oh boy. That is all tough news. But glad to hear bailey is coming home early! What a trooper. I can say Winsley didn't bounce back that quickly but she is hanging in there. Love our dogs don't we all. hang in there Bailey. Winsley was suppose to have her ultrasound of her liver tomorrow. I just cancelled it. They want me to bring her in at 8:30 and pick her up at 4:30 so she can just be there when the dr is ready. I feel frustrated. The poor thing hyperventilated when we drive past the vet let alone drop her off again. I feel that the vet has become insensitive to us. She is still off her Piroxicam. I was waiting until tomorrow but now who knows. She barely eats and I am basically hand feeding her. Other than that she is soon ok. She doesn't appear in pain, however I don't know what to look for. She is just high anxiety (as always). Ugh I really hate his battle. I am just trying to live with her here with us everyday. Wdog47 Wed, 18 Apr 2012 00:00:00 GMT Thank you all for the support.  My little girl bounced right back and was up and about a few hours after the surgery.  They are letting me bring her home today.  I may try upping her dosage of the salvestrols or possibly consider the oral neoplasene.  Just don't want to let this TCC win out in the end! To top it all off, my friend's fiance just got diagnosed with colon cancer at 41 years old.  We've got to find a cure! Baileysmom97 Wed, 18 Apr 2012 00:00:00 GMT On Apr 17, 2012 10:53 PM SienasMom wrote: Tell Bailey she has the entire TCC board cheering for her fast recovery from surgery!  :-)  I wish you strength and all the best as you go through this.Ditto Take some time for yourself now and REST.  I know how horrible and hectic this all becomes.  Wishing you the best. Mila01 Wed, 18 Apr 2012 00:00:00 GMT Tell Bailey she has the entire TCC board cheering for her fast recovery from surgery!  :-)  I wish you strength and all the best as you go through this. SienasMom Tue, 17 Apr 2012 00:00:00 GMT Thanks to everyone for the good wishes.  Unfortunately Dr. could not remove the tumor, could only debulk it because it was too close to the ureters and felt they would not be able to close the bladder properly if they tried removing it.  Stents were placed into the ureters to keep them from becoming blocked when this cancer keeps going so this buys her some more time.  She will likely stay in the hospital a few days to make sure all is ok. Baileysmom97 Tue, 17 Apr 2012 00:00:00 GMT On Apr 17, 2012 7:30 PM Baileysmom97 wrote: I just got an update from the doctor and the tumor was right around the ureters so they're not sure they will be able to get good margins and there is a strong likelihood stents will be put in.  This was just a big punch in the gut.Oh Karin, So sorry to hear this. I am sure this is not what you wanted to hear. :(Will bailey come home today? Wdog47 Tue, 17 Apr 2012 00:00:00 GMT I just got an update from the doctor and the tumor was right around the ureters so they're not sure they will be able to get good margins and there is a strong likelihood stents will be put in.  This was just a big punch in the gut. Baileysmom97 Tue, 17 Apr 2012 00:00:00 GMT Sorry to hear about Bailey. All the best for the surgery, i hope it goes well. Thinking of everyone going through this with their little mates, it's truly an awful experience and can be hard to live in the now when the road ahead is so unknown and unpromising. poppy06 Tue, 17 Apr 2012 00:00:00 GMT Thanks for your kind thoughts.  Sorry to hear about your news.  This is such a beast of a disease.  Keep on fighting and enjoy the time you have!  We did the park routine this past weekend and I'm hoping there will be more.  I wish you the best also. Baileysmom97 Tue, 17 Apr 2012 00:00:00 GMT I'm so sorry - I will be thinking of you and Bailey and hoping everything goes well for both of you.  We  got a call from our vet today after she had the ultrasound looked at by a radiologist specialist - they are giving her about 6 months - urethra cancer and it's usually agressive.  She will order the Chinese herbs but they won't be in till next week.  We are going to our favorite park this weekend and let her hike till her heart is content.  Good Luck to you. Mila01 Tue, 17 Apr 2012 00:00:00 GMT Just wanted to post an update.  We went for an ultrasound today and found that the tumor grew despite the one round of chemo.  Surgery is scheduled for Tuesday morning so we will see how that goes.  The surgeon feels the time is now because the tumor is at the opposite side away from the ureters.  Most likely they will be removing up to half of the bladder to obtain good margins.  Now to complicate matters a bit, Bailey is anemic and also has high blood pressure.  I am hoping for the best! Baileysmom97 Tue, 17 Apr 2012 00:00:00 GMT Thank you Susan I tried getting back on with my old user name but it would not accept me so now I'm just Mila01.  I live in a small town in  Michigan and have had to drive 1 hr away to seek additional treatment which we did this past Saturday - they did an ultrasound and found a mass in her urethra and she is sending it on to a radiologist specialist to look at.  We have declined chemo and radiation (as it has been suggested) for financial and the physical damage it does.  My father-in-law suffered through it for leukemia and I would rather let her go than see her endure what he experienced and it didn't end up giving him any extra time.  This vet also practices Chinese herbal medicine as well as accupunture and is looking into a product called Shao Fu Zhu Yu Wan along with curcumin.  There is some vet site calledwww.vin.comtha t only vets can get into and I was lucky enough to find a local one that is giving me some help and she printed off this info.  Supposedly this gentleman said he used these herbs with great success.  Within 60 days he had a complete remission on both of his cases.  He himself is also a cancer survivor of more than 5 years and used them himself.  His message board was dated 2/21/11.  So the young lady who practices the Chinese herbs with also did the ultrasound for me is looking into getting them for me.  I started the curcumin today - 150 mg 3xday but only got one dose in her as later in the day she started refusing any additional food - I think it may be the curcumin?? Will try again tomorrow if she shows an appetite otherwise I'll call this vet back and ask for suggestions.  Keeping my fingers crossed.  Good luck to you as well:)  Mila's mom, Pam  Mila01 Mon, 16 Apr 2012 00:00:00 GMT Just found this site - looking for info to help me with my little girl (mini schnauzer) who is 10.5 and I've gone to 3 vets now who all think she has some type of uterine cancer due to the spontaneous bleeding.  She started Piroxicam last Saturday but had the compounding pharmacy make it up as a cream/gel which is rubbed into her ears.  This was done to hopefully bypass the gastro issues as she has had many in her 10+ years.  I am curious to know how many of you have switched to raw food diet and did it help?  I have started steaming veggies but started giving her raw meat (turkey to start with).  She has been on Z/D low allergen most of her life due to undiagnosed allergies - testing was done and it said she wasn't allergic to anything yet itches constantly when we tried various commercial and prescription diets until z/d.  Mila01 Mon, 16 Apr 2012 00:00:00 GMT Hi Gussie-- Dr. Fox's website is buckmountainbotanicals.net There's a lot of good information and case studies on the website.  Dr. Fox is also very willing to consult with other vets to help them with the Neoplasene. Baileysmom97 Fri, 13 Apr 2012 00:00:00 GMT On Apr 12, 2012 6:25 AM Pinkest wrote: Hi everyone... unfortunately I am a new member of this community - my 10yo Boxer, Rosie, is a confirmed member of the bladder cancer community.  She started displaying symptoms on Boxing Day (Dec 26) with the "ghost-squatting" after her normal urination that, as it seems so many others have witnessed and 'assumed' UTI.  Whipped her off to the Vet, who could find nothing, but popped her onto precautionary antibiotics.  After 2 weeks, no improvement, so by this time with the holiday period over, we took her to her family vet who also found nothing, and also popped her onto AB's.  Still the phantom squatting continued, and my troubled intuition went into over-drive.  Back to the Vet we went, this time for an ultrasound, which showed nothing.  The assumption at that time was that it was the beginnings of a tumour at the urethra/bladder junction, which are considered mostly inoperable (in Aus) due to their position, so we were prepared {so I thought} for a worst case scenario.  Rosie was pretty much herself, but was losing weight very slowly.  She developed an infection over a holiday weekend, and dropped her appetite almost completely, and managed to lose 2kgs (almost 5 pounds) in 4 days.  Straight back tothe Vet and back onto the AB's, which returned her appetite almost immediately.  At that point, we booked her in for a biopsy and scans to figure exactly what we were looking at dealing with... and the results were encouraging - a frontal tumour (so, removable, yay!) rather than a necked position.  The smear test from the lab came back with nothing necrotic or infected - another plus.  So, surgery was scheduled for this past Tuesday.  So that's 10 weeks since the first symptoms were discovered.  Unfortunately, when her Vet got into her tummy, her bladder tumor has grown through her bladder wall and attached to her abdo cavity muscle, and her belly is full of secondary or seed tumours.  I am gutted, heartbroken and horrifed, as I know that now, it's just a question of when, not if.  We have been offered chemo, but given her age (10-and-almost-a-half), and that chemo will only add quantity whilst subtracting quality of life, we are going to forego it.  I've been 'Dr-Googling' today - which is where I came across this fabulous site - and am very interested in Graviola - but am quite wary of trying it, given how many 'anti' reports there are along with the 'miracle cure' stories.  Ultimately I want to provide Rosie with the best 'rest of your life' experience that I can, whether that is for 6 day, 6 weeks, or 6 months... and given how agressively this has attacked her, it's not likely to be 6 months.  I'm sorry for the long post, but there is not much information in Australia about alternative therapies, let alone those for our canine patients, and I'd really love to get some feedback from fellow carers.  Thanks so much.Hi, So sorry to hear about Rosie.  Please know that we on this site will be here to support you.  I am Nita, and my dog Rocky (a standard dachshund) was diagnosed last August, tcc having been suspected since May.  I'm so lucky that in a year he has not had symptoms of the disease (tumor first seen on an ultrasound).  He is receiving conventional treatment, Piroxicam and Chemo.  He takes Metaclopromide and Pepsid.  His tumor was in a lucky area of the bladder, but now,( though the tumor was removed when a surgical biopsy was performed),  ultrasounds are showing an uneven thickening around the whole bladder wall.  Originally the vet thought we'd have him till about July. I keep hoping its longer than that, but I think this disease is fairly unpredictable.   My heart goes out to you and Rosie as it does for all of us on this site.  If there is anything I can do to help, please let me know.  Nita Fri, 13 Apr 2012 00:00:00 GMT On Mar 07, 2012 2:50 AM Shelbysmom2 wrote: Just to let you all know that my dog Shelby was diagnosed in August 2011 with TCC.  I read on this blog about Neoplasene.  I found a holistic vet in the area and she really opened my eyes about the type of diet Shelby should be on, the supplements and when I brought up Neoplasene she was willing to try it.  She was not willing to do the infusion method as mentioned on the Buck Mountain Botanicals website (Dr. Fox) but she put Shelby on an oral dose.  Things went along without incident until January 2012.  Then one day Shelby urinated a large puddle in the kitchen and it was full of blood and something that looked like clots.  I thought for sure her cancer had worsened.  When I took her 2 weeks later for her regular ultrasound, the vet was amazed to find that her tumor was completely gone!  Yes, I mean completely!!!  Today, she went back for another ultrasound (its been 7 weeks) and the tumor is still gone!  She is feeling good and acting like her old self again!  Please, please find a holistic vet and give this Neoplasene a try.  She is also on Piroxicam twice a week.  If anyone would like more information from me, please feel free to email me Message edited by CancerCompass staff. For personal protection,email address removed. Consider private reply. Please review CancerCompass Member Guidelines athttp://www.cancercompass.com/common/guidelines.html  !! But know there is hope out there!  Shelby is going to be 14 in April.  My vet is so excited about this treatment (Shelby was the first dog she tried on it), she would be happy to talk to anyone's vet who wants more info tooHi Shelbysmom2! I am so excited about your success with neoplasene. My sister's dog Missy has been diagnosed with inoperable bladder cancer. She was given antibiotics after dental surgery and then seemd to developed the cancer right afterwards and had blood in her urine. The vet then put Missy on Piroxicam and only gave her a few weeks to a few months at best. They were referred to a homeopathic vet in Vermont who did not like the Piroxicam and took her off that and all antibiotics. He put her on a restrictive diet and started using the plussing method to treat her. She seems much healthier and happier now, but he is not willing to try any other methods. I want her to look into this neoplasene to try to save Missy as he has not had actual cures, but prolonged life up to 1.5 years at best... I didn't know neoplasene could be given orally or injected. I have used the salve, but my dogs lick it off. I am going to ask my vet about the neoplasene to be given orally and/or infusing the area directly. Please send me the contact info for Buck Mountain Botanicals and Dr. Fox and of course your vet also, for reference to my vet and my sister for all the details... Thanks so much for posting your story! My best wishes to you and everyone! Gussie LoveAllAnimals Fri, 13 Apr 2012 00:00:00 GMT On Apr 12, 2012 6:25 AM Pinkest wrote: Hi everyone... unfortunately I am a new member of this community - my 10yo Boxer, Rosie, is a confirmed member of the bladder cancer community.  She started displaying symptoms on Boxing Day (Dec 26) with the "ghost-squatting" after her normal urination that, as it seems so many others have witnessed and 'assumed' UTI.  Whipped her off to the Vet, who could find nothing, but popped her onto precautionary antibiotics.  After 2 weeks, no improvement, so by this time with the holiday period over, we took her to her family vet who also found nothing, and also popped her onto AB's.  Still the phantom squatting continued, and my troubled intuition went into over-drive.  Back to the Vet we went, this time for an ultrasound, which showed nothing.  The assumption at that time was that it was the beginnings of a tumour at the urethra/bladder junction, which are considered mostly inoperable (in Aus) due to their position, so we were prepared {so I thought} for a worst case scenario.  Rosie was pretty much herself, but was losing weight very slowly.  She developed an infection over a holiday weekend, and dropped her appetite almost completely, and managed to lose 2kgs (almost 5 pounds) in 4 days.  Straight back tothe Vet and back onto the AB's, which returned her appetite almost immediately.  At that point, we booked her in for a biopsy and scans to figure exactly what we were looking at dealing with... and the results were encouraging - a frontal tumour (so, removable, yay!) rather than a necked position.  The smear test from the lab came back with nothing necrotic or infected - another plus.  So, surgery was scheduled for this past Tuesday.  So that's 10 weeks since the first symptoms were discovered.  Unfortunately, when her Vet got into her tummy, her bladder tumor has grown through her bladder wall and attached to her abdo cavity muscle, and her belly is full of secondary or seed tumours.  I am gutted, heartbroken and horrifed, as I know that now, it's just a question of when, not if.  We have been offered chemo, but given her age (10-and-almost-a-half), and that chemo will only add quantity whilst subtracting quality of life, we are going to forego it.  I've been 'Dr-Googling' today - which is where I came across this fabulous site - and am very interested in Graviola - but am quite wary of trying it, given how many 'anti' reports there are along with the 'miracle cure' stories.  Ultimately I want to provide Rosie with the best 'rest of your life' experience that I can, whether that is for 6 day, 6 weeks, or 6 months... and given how agressively this has attacked her, it's not likely to be 6 months.  I'm sorry for the long post, but there is not much information in Australia about alternative therapies, let alone those for our canine patients, and I'd really love to get some feedback from fellow carers.  Thanks so much.Hi there! Please look for a holistic vet and check out the posts on others who have used neoplasene orally to rid the body of the bladder cancer... I'll check to find out and reply back with all the contact info... LoveAllAnimals Fri, 13 Apr 2012 00:00:00 GMT Hi! I'm so sorry about your Huey! My sister's dog Missy was diagnosed with inoperable bladder cancer just over 5 weeks ago after having dental surgery and then receiving antibiotics and prilicam. The vet only gave her a few weeks to a few months also. But then she referred them to a homeopathic vet. He did not like the proxicam (I think that's what it is?) and took her off all meds and started treating her with the plussing method. She's doing much better, but he does not want to try anything else. That concerns me because I think the neoplasene can really help Missy and so many others including your Huey! I think you should consider trying the neoplasene infusion and/or orally also if you can find a holistic vet who will do it. I am going to tell my sister about this also and ask my holistic vet about neoplasene tomorrow since I have an appt with my boy who had a tumor that turned out to be benign... thank GoD!... I'll let you know but please don't give up... You can find holistic vets and the different modalities they use at: American Holistic Veterinary Medical Association  website: http://www.ahvma.org/ That's where I find my holistic vet and she is great and is fair on the pricing... not crazy... She's in upstate NY if you're in the area, I'll give you her contact info... Good luck and I'll pray for Huey and you too! All the best, Gussie LoveAllAnimals Fri, 13 Apr 2012 00:00:00 GMT Hi! I'm so sorry about your Huey! My sister's dog Missy was diagnosed with inoperable bladder cancer just over 5 weeks ago after having dental surgery and then receiving antibiotics and prilicam. The vet only gave her a few weeks to a few months also. But then she referred them to a homeopathic vet who is doing the plussing method on her and she seems better. I think you might want to try the neoplasene infusion and/or orally also if you can find a holistic vet who will do it. I am going to tell my sister about this also and ask my holistic vet about neoplasene tomorrow since I have an appt with my boy who had a tumor that turned out to be benign... thank GoD!... I'll let you know but please don't give up... You can find holistic vets and the different modalities they use at: American Holistic Veterinary Medical Association  website: http://www.ahvma.org/ That's where I find my holistic vet and she is great and is fair on the pricing... not crazy... She's in upstate NY if you're in the area, I'll give you her contact info... Good luck and I'll pray for Huey and you too! All the best, Gussie LoveAllAnimals Fri, 13 Apr 2012 00:00:00 GMT On Apr 12, 2012 4:56 AM Milasmom01 wrote: I just found this site and wanted to add what we have started with my mini schnauzer who is 10.5 - Mila.  Results of urine culture were inconclusive but I've visited 3 separate vets and they all think it is bladder cancer so she was started on the Piroxicam but I requested it in cream/gel form.  We just got it this past Saturday 4/7 and beginning applying 0.1ml at bedtime and it was because of her extremely sensitive stomach.  The cream/gel bypasses the organs and feeds directly into the blood stream so dosing is adjusted for the added strength this gives the medication.   My beagle also has TCC. Diagnosed Jan. 2nd this year. My oncologist taught at the university of TN. Veterinary school. He started Chloe on Mobic instead of piroxicam because of the problems it causes the stomach. We also started chemo every 3weeks. Ultrasound after 3 rounds showed the tumor to have slightly shrunk. We are continuing chemo every 4 weeks and will do another ultrasound after 3 rounds. There has been no visible side effects from the chemo or Mobic. Have you had an ultrsound done? It will show the area of the tumor. Chloe's is in the trigone area which is the worst place to be. I try not to think of what is to come. Thinking of you and wishing you the best! Chloe's mom, Susan Chloebeaglemom Thu, 12 Apr 2012 00:00:00 GMT Hi everyone... unfortunately I am a new member of this community - my 10yo Boxer, Rosie, is a confirmed member of the bladder cancer community.  She started displaying symptoms on Boxing Day (Dec 26) with the "ghost-squatting" after her normal urination that, as it seems so many others have witnessed and 'assumed' UTI.  Whipped her off to the Vet, who could find nothing, but popped her onto precautionary antibiotics.  After 2 weeks, no improvement, so by this time with the holiday period over, we took her to her family vet who also found nothing, and also popped her onto AB's.  Still the phantom squatting continued, and my troubled intuition went into over-drive.  Back to the Vet we went, this time for an ultrasound, which showed nothing.  The assumption at that time was that it was the beginnings of a tumour at the urethra/bladder junction, which are considered mostly inoperable (in Aus) due to their position, so we were prepared {so I thought} for a worst case scenario.  Rosie was pretty much herself, but was losing weight very slowly.  She developed an infection over a holiday weekend, and dropped her appetite almost completely, and managed to lose 2kgs (almost 5 pounds) in 4 days.  Straight back tothe Vet and back onto the AB's, which returned her appetite almost immediately.  At that point, we booked her in for a biopsy and scans to figure exactly what we were looking at dealing with... and the results were encouraging - a frontal tumour (so, removable, yay!) rather than a necked position.  The smear test from the lab came back with nothing necrotic or infected - another plus.  So, surgery was scheduled for this past Tuesday.  So that's 10 weeks since the first symptoms were discovered.  Unfortunately, when her Vet got into her tummy, her bladder tumor has grown through her bladder wall and attached to her abdo cavity muscle, and her belly is full of secondary or seed tumours.  I am gutted, heartbroken and horrifed, as I know that now, it's just a question of when, not if.  We have been offered chemo, but given her age (10-and-almost-a-half), and that chemo will only add quantity whilst subtracting quality of life, we are going to forego it.  I've been 'Dr-Googling' today - which is where I came across this fabulous site - and am very interested in Graviola - but am quite wary of trying it, given how many 'anti' reports there are along with the 'miracle cure' stories.  Ultimately I want to provide Rosie with the best 'rest of your life' experience that I can, whether that is for 6 day, 6 weeks, or 6 months... and given how agressively this has attacked her, it's not likely to be 6 months.  I'm sorry for the long post, but there is not much information in Australia about alternative therapies, let alone those for our canine patients, and I'd really love to get some feedback from fellow carers.  Thanks so much. Pinkest Thu, 12 Apr 2012 00:00:00 GMT I just found this site and wanted to add what we have started with my mini schnauzer who is 10.5 - Mila.  Results of urine culture were inconclusive but I've visited 3 separate vets and they all think it is bladder cancer so she was started on the Piroxicam but I requested it in cream/gel form.  We just got it this past Saturday 4/7 and beginning applying 0.1ml at bedtime and it was because of her extremely sensitive stomach.  The cream/gel bypasses the organs and feeds directly into the blood stream so dosing is adjusted for the added strength this gives the medication.    Milasmom01 Thu, 12 Apr 2012 00:00:00 GMT On Apr 11, 2012 9:16 AM LittleKaren wrote: Dear BudBoysMom, So sorry to hear of your loss! My Emily Beagle is fighting the fight and I am so grateful for each day with her! I can only imagine what it must be like to come home and not have that loving, excited, often loud beagle greeting! Your Buddy was a lucky beagle to have you adopt him later in life and then to love him so...which, along with food, is the greatest joy in a beagle's life! They love their people! Know that there are others thinking of you and giving you a virtual hug! Karen, Emily and MurphyDear Karen, Thank you so much for your condolences. Today is the 3 week anniversary of Buddy's death. I still miss him every day and am so thankful to have my cocker spaniel Daisy to help me deal with my grief. I hope your Emily fights the fight for a good long time. Jennifer BudBoysMom Wed, 11 Apr 2012 00:00:00 GMT Hello, I found this link and emailed to offer DNA samples from Emily, who has TCC, and Murphy (Sheltie) who does not. It explains the research and the goals of the research. The link says Scotties, Westies, and Shelties, but they also want ANY breeds' DNA who has a diagnosis (biopsy) of TCC.  Didn't know if anyone might want to also volunteer doggie DNA samples. I figure anything to help fight this I want to contribute to if I can! http://www.akcchf.org/research/participation-needed/DNA-Samp LittleKaren Wed, 11 Apr 2012 00:00:00 GMT Dear BudBoysMom, So sorry to hear of your loss! My Emily Beagle is fighting the fight and I am so grateful for each day with her! I can only imagine what it must be like to come home and not have that loving, excited, often loud beagle greeting! Your Buddy was a lucky beagle to have you adopt him later in life and then to love him so...which, along with food, is the greatest joy in a beagle's life! They love their people! Know that there are others thinking of you and giving you a virtual hug! Karen, Emily and Murphy LittleKaren Wed, 11 Apr 2012 00:00:00 GMT Thank you so much for this info.  I will surely try to switch to Metacam.  The holistic vet here refused to try Neoplasene orally because she has used it topically on horses with results that she called "horrific".  She said it got rid of the tumor but caused other unspeakable damage.  I think the oral drug works differently,  but she felt it could cause more harm than good because of the location of Rio's tumor.  Iloverio Fri, 06 Apr 2012 00:00:00 GMT The doctors switched Bailey to Metacam because they felt that perhaps the tumor had become resistant to the Piroxicam.  Piroxicam seems to be the drug of choice because it seems to inhibit tumor growth and in some cases will cause the tumor to shrink.  With some of the newer NSAIDS there is just not enough experience yet to show if they really work but they seem to be much easier on the stomach. Bailey is being treated at UPENN Veterinary Hospital in Philadelphia and they are up to date with the latest information.  Bailey's first doctor was also willing to try the Neoplasene if I wanted to go that route.  I can always get an honest answer from them.  If you need anything further, just let me know. Baileysmom97 Fri, 06 Apr 2012 00:00:00 GMT This is good information to know!  Thank you.  do you know of anything else that could replace Piroxicam?  The veterinary oncologist told me all NSAIDs have the same potential risks and side effects.  I looked online and found something called Elara Vaxamine-K9, but it has some mixed reviews as to whether or not it is effective.  The constant stress on my dog when he was off the pain-killer was so terrible that I felt I had to put him back on.  Iloverio Thu, 05 Apr 2012 00:00:00 GMT On Apr 05, 2012 9:31 PM Iloverio wrote: My experience with Piroxicam was little different.  My dog, Rio, had no appetite, was trembling all the time and panting heavily when he was first diagnosed with TCC.  After the Piroxicam kicked in (maybe 4 days or so), he started to feel a lot better.  In fact, I tried to bring his dosage down to every other day instead of daily after 6 months, and the trembling and panting started up again.  So now he is back on.  The stomach ulcer worry would be after several months or even years on the drug -- that's why antacids should be given with it.  If you read up on Piroxicam, it is an NSAID -- a non-steriodal anti-inflammatory drug -- it reduces inflamation and can actually help shrink the tumor.  I think I would look at how Winsley was acting before as well as after Piroxicam.  I am right with you at having to leave your dog -- I hired someone because my husband and I have to leave for a weekend.  I usually have a friend watch Rio, but I feel it is so much to ask that I am paying a professional to take care of him in her home.  I have been so stressed about it.  Rio is now on natural medicine -- Chinese herbs and mushroom drops and fish oil, plus Piroxicam and antacids.  I home-cook meals every night and he has had acupuncture.  It is a lot to deal with.  You sound like a wonderful caretaker.  Try fresh water salmon and ground sirloin -- but cook them up and maybe freeze meal-size portions.  Rio is not fussy about eating any more because he loves this diet.  I cook up spinach or broccoli or kale and mix it in.  the natural vet recommended straight protein and green veggies or carrots and sweet potatoes. Just to point out, the stomach ulcer can happen at any time.  With Bailey it happened twice during the last year where she had to be taken off the piroxicam because of stomach issues.  Usually you can tell by the color of the stool.  I know on my bottle of piroxicam there is a warning to watch out for dark, tarry stools and if the dog vomits anything that looks like coffee grounds. Baileysmom97 Thu, 05 Apr 2012 00:00:00 GMT My experience with Piroxicam was little different.  My dog, Rio, had no appetite, was trembling all the time and panting heavily when he was first diagnosed with TCC.  After the Piroxicam kicked in (maybe 4 days or so), he started to feel a lot better.  In fact, I tried to bring his dosage down to every other day instead of daily after 6 months, and the trembling and panting started up again.  So now he is back on.  The stomach ulcer worry would be after several months or even years on the drug -- that's why antacids should be given with it.  If you read up on Piroxicam, it is an NSAID -- a non-steriodal anti-inflammatory drug -- it reduces inflamation and can actually help shrink the tumor.  I think I would look at how Winsley was acting before as well as after Piroxicam.  I am right with you at having to leave your dog -- I hired someone because my husband and I have to leave for a weekend.  I usually have a friend watch Rio, but I feel it is so much to ask that I am paying a professional to take care of him in her home.  I have been so stressed about it.  Rio is now on natural medicine -- Chinese herbs and mushroom drops and fish oil, plus Piroxicam and antacids.  I home-cook meals every night and he has had acupuncture.  It is a lot to deal with.  You sound like a wonderful caretaker.  Try fresh water salmon and ground sirloin -- but cook them up and maybe freeze meal-size portions.  Rio is not fussy about eating any more because he loves this diet.  I cook up spinach or broccoli or kale and mix it in.  the natural vet recommended straight protein and green veggies or carrots and sweet potatoes.  Iloverio Thu, 05 Apr 2012 00:00:00 GMT Hi Sherri--You might want to stop the piroxicam for awhile, maybe atleast until you get back.  It can cause stomach ulcers, especially if there's not enough food in the stomach.  This might be contributing to Winsley not wanting to eat.  I had some of the same worries about Bailey not eating when she was feeling the effects of the chemo.  She went a few days without eating anything but I would keep trying different foods and then finally she would eat a little.  She's still not completely back to normal as far as eating.  Baileysmom97 Thu, 05 Apr 2012 00:00:00 GMT I am so sorry for what you are going through.  In my experience with Piroxicam, it starts to kick in after a few days, and my dog started to feel better. In fact, I recently tried to take down Rio's dosage to every other day, and I noticed he was distraught, panting heavily and shaking -- this is how he acted when first diagnosed and before Piroxicam.  So I have had to administer it daily.  I am right with you about going out of town.  I have to leave on a business trip, and my husband will be out of town and my daughter as well.  I hired someone to take care of him in her home.  Normally I would leave him with a friend, but I am not sure I can put anyone else through it.  Rio takes Chinese herbs I crush and put into his food as well as Piroxicam, fish oil, mushroom drops  and 2 antacids a day. I took him to a Natural Vet last week because the chemo is no longer effective.  He had acupuncture.  So you are not alone -- I know just how it feels to be so sad and helpless.  Rio seems happy and loves his homecooked meals every night -- my poor husband is always asking if the ground sirloin and fresh salmon are for him or for Rio.  But we do what we can for as long as we can.  I will pray that Winsley will feel bettr.  It sounds like you are doing all you can.  Piroxicam really helped Rio. Iloverio Thu, 05 Apr 2012 00:00:00 GMT Thanks. Winsley is not eating much. I have tried everything today. She ate a few animal crackers and milk bones and a Greenie and some whipped creme with her meds. Although she doesn't want them. When we go walking she is happy. Tomorrow our family leaves for san Diego. I have been crying all night bc I don't want to go. But I have to take my two children there. I am worried she will get depressed and stop eating altogether. I have someone staying with her but I am so nervous to go. What if she just stops eating? How many days can she go? Meanwhile I started Pepcid today hoping that would help relief any nausea she may have. I am bothered my vet never suggested this. Ugh. I hate that I am losing her. And now I am losing this whole week. :( Wdog47 Thu, 05 Apr 2012 00:00:00 GMT Hi Sherri-- Sorry to hear that Winsley is still not doing so well.  The doctor put Bailey on a quarter tablet of Pepcid (famotidine) 2x a day when she was started on the piroxicam.  You could certainly try that even if you cannot get in touch with your vet. Baileysmom97 Tue, 03 Apr 2012 00:00:00 GMT Yes, Piroxicam can cause an upset stomach. You should call your vet. they can suggest something to help the symptoms. SienasMom Tue, 03 Apr 2012 00:00:00 GMT Hi, I hope I am using this forum correctly.  My dog Winsley is 12.5 and dx'd with TTC 3 weeks ago.  She has stopped eating most of her food and I have to hand feed her.  She will eat a couple of bites, but it is usually not much.  She will eat greenies and last night I figured to put her Piroxicam in whipped cream to get it down.  Does anyone know is it the piroxicam that causes loss of appetite?  I have to leave out of town with my husband and kids.  I am devastated to leave.  I am worried she will get depressed and something will happen while I am gone.  She is still walking pooping little play, but not much.  Just seems anxious mostly.  Any experience, suggestions I would love.  I am sorry about to read about Buddy.  My prayers are with all the pups.  Sherri Wdog47 Tue, 03 Apr 2012 00:00:00 GMT Ok, this is Shelby's regimen:  Reglan 10 mg 3 30 min before each meal, L-Glutamine Powder 1 teaspoon mixed in food in the morning, C3 Curcumin Complex one in the morning with her food, Duralactin 1000 mg one with morning food and one with evening food, Probiotic Synergy one with morning food and one with evening food, Fish Oil 4000 mg a day.  I use a pump and it is 4 pumps into each food bowl.  Piroxicam one on Monday and one on Friday.  Then after each meal we give her about a tablespoon and a half of greek yogurt with a tablespoon of Firm Up and the 2 cc of Neopleasene mixed in.  That all. (thats a lot!).  I tried giving her the neoplasene in a meatball but she did not like it.  She laps it right up in the greek yogurt.  At first I gave her plain yogurt because she is supposed to be on low carbs but then I switched to honey flavored or vanilla flavored.  I figured it couldn't hurt her to have something that tasted better.  She is on a grain free diet too.  I looked into blue buffalo but it has oatmeal (I think) in it.  So that's when we went to giving her rotisserie chickens from Costco.  I pick a whole chicken into a ziplock and then add a can of french cut green beans and freeze it.  I look like a nut checking out at Costco with 6 chickens in my cart!  It is so much work to carry out this routine but we love her so much that we don't care.  We started her on 1 cc twice a day too and then went up to 2cc after a month I think.  I am hoping she can go back to 1cc soon.  Our vet is looking into a maintanence dose for her.  The only concern I have is that she still squats for a long period of time and urine comes out good at first and then begins to dribble.  It takes her forever to pee.  But the vet said she has a narrowing of her bladder wall and that is not going away.  But the tumor is gone and it was pretty good size.  Siena might be having some nausea.  I would ask the vet about the Reglan.  I think it helped Shelby not to get nauseated.  Also, the greek yogurt would help and I don't think it would hurt.  Ask your vet.  Shelby weighs about 50 pounds so very close to Siena.  Just be aware that it took Shelby 5 months before her tumor disappeared.  We were happy that it was just staying the same size and really had no hope that it might disappear but when it did of course we were thrilled.  And we had a biopsy so I know she did have tcc no question.  Also, you are right to give her the Neoplasene last after she eats.  It should not be given on an emply stomach.  I'm sorry this is so long but I want to help anyone who is going through this if possible.  I don't know if this could possibly work for anyone else.  I only know it worked for us for now.  Maybe it will come back..I don't know.  I'm taking one day at a time right now.  Yes, we are in Collierville, just outside of Memphis.  Good luck to you and Siena.  I pray for her recovery.  By the way, how old is she??? Shelby is 13!!!  She's a trooper though. A goldne retriever mix with a big heart! I wish I could post a picture on here of her sweet face.  Let me know if you have any other questions! Shelbysmom2 Sun, 01 Apr 2012 00:00:00 GMT It's so nice to be able to talk to someone who's been through this before. Thanks! Yes, Siena is getting an oral dose. We are starting at 1 cc two times a day. She is 54 lbs. So far, she has kept the neoplasene down but I think she might have a tummy ache. She seems like she doesn't feel quite right. Did Shelby take right to it or did she have an 'adjustment period'? Also, I feed her dinner first and then give the med soaked into a tiny bit of bread and then wrapped inside a ball of soft dog food (blue buffalo). She spit part of it out this morning, so I added more soft food and she took it. Just wondering if you have any tricks you use to feed it to Shelby? Lastly, do you have her on any immunity supplements? I am continuing with fish oil, but nothing else. The vet gave me some vitamins, but the buck mountain website says it's better to administer it alone. As always, there's plenty of conflicting info on treatments! Thanks again and I'm glad Shelby is doing so well! Did I read you are in Memphis? I grew up there, but I'm in Salt Lake now. Definitely different! SienasMom Sun, 01 Apr 2012 00:00:00 GMT Wow! I'm so glad you're vet thinks it's worth a try.  My Shelby continues to do well with the Neoplasene treatment.  Is she going to give it as an oral dose?  If so, Shelby did have diarrhea at first but I put her on Firm Up which is a pumpkin supplement that completely took care of the diarrhea.  She now gets the firm up mixed in with greek yogurt and the liquid Neoplasene after she eats.  She also gets a pretreat before eating of 3 reglan pills a half an hour before she gets her food.  This helps with nausea.  She has never acted like her stomach has given her trouble because she is always willing to eat so I'm hoping that she is not experiencing nausea.  I wish the best for you and Sienna.  Keep us posted. Shelbysmom2 Fri, 30 Mar 2012 00:00:00 GMT Brenda, Thanks for your kind words about my Buddy. I'm so thankful that he didn't suffer for long. He stayed healthy for a long time, except for the constant need to pee. I will try to stop second guessing myself though it's really tough. I know he knew how much I loved him because of how much love he showed me. I hope your journey of grieving for Bella is at least not as intense at this point, though I remember from other dogs of mine dying it can take a really long time. I will always grieve my other dogs and Buddy and remember them in special ways. Thanks for the hugs. I send hugs back to you. Jenn, Buddy's Mom BudBoysMom Thu, 29 Mar 2012 00:00:00 GMT Debbie, Thank you for your prayers. I know I need them right now. My other dog Daisy (cocker spaniel) is a definitely a great comfort to me right now. She makes me have to get up and do things when I might just sit and cry. I thank God for her. Jenn BudBoysMom Thu, 29 Mar 2012 00:00:00 GMT Karin- Thanks for your kind words. I do take comfort in knowing that he's at peace and enjoying all the fun there is at the Rainbow Bridge. Jenn, Buddy's Mom BudBoysMom Thu, 29 Mar 2012 00:00:00 GMT I'm so sorry to hear about your furbaby Buddy.  It's awful to  watch our dear friends when they get to the end.  But they know that they are loved and that means a lot to them.  Buddy is at peace now.  Don't try to second guess yourself about the hows and whens.  You actions were motivated out of love and that's all that matters.  {{{ Hugs }}} to you. Brenda (who is still not over the loss of Bella) MomToBella Thu, 29 Mar 2012 00:00:00 GMT Hi Nita (Rocky's Mom): Thank you for your comment about that I did everything I could do for my Buddy. Intellectually I know that, but emotionally I keep thinking I could have done more. It helps to have people tell me I did all I could. I thought I had prepared myself to experience the pain of loss yet again (we had 5 dogs during my childhood years, my first cocker spaniel died in 2004 from heart disease and I had to choose to help my first beagle Bandit go to the Rainbow Bridge in 2007 due him having pancreatic cancer). I'm not sure you really can prepare yourself ahead of time. Thanks again for your kindness. Jenn (Buddy's Mom) BudBoysMom Thu, 29 Mar 2012 00:00:00 GMT Dear Maureen (Copper's Mom)- Thanks for replying. It is so tough to let them go; they are part of our everyday lives and truly enrich our lives. Imagining Buddy and Copper howling together made me smile. Buddy loved to "sing" along with certain songs on the stereo or tv so I imagine they are singing some, too. Jenn (Buddy's Mom) BudBoysMom Thu, 29 Mar 2012 00:00:00 GMT jenn-- Thank you for your kind words. It helps to know others understand how tough this is for me. Jenn, Buddy's "mom" BudBoysMom Thu, 29 Mar 2012 00:00:00 GMT I spent the morning with a holistic vet who has used Neoplasene quite a bit in treating a variety of cancers, including TCC. She shared with me several cases where it has been effective in her practice and after much reading and research, I decided to give it a go instead of chemo or surgery. I've got my fingers crossed and will share Siena's experiences with this community. You have all been a tremendous resource for me in the aftermath of her diagnosis. Thank you all! SienasMom Thu, 29 Mar 2012 00:00:00 GMT Buddy's Mom, Very, very sorry to hear about Buddy.  As Debbie said, I wish none of us had to go through this.  It is such an up and down ride and you never know what's coming.  Hope you can take some comfort in the fact that he's at peace and no longer suffering. Karin Baileysmom97 Thu, 29 Mar 2012 00:00:00 GMT On Mar 27, 2012 6:36 AM poppy06 wrote: Hi Susan, yep i'm pretty sure it is mitoxantrone that she's on for her chemo. Poppy seems to be a bit better today, so fingers crossed that she just keeps getting better now.  Am really glad to hear that Chloe is still showing no side effects, that is very cool.  Have you had an updated ultrasound or one planned?  Will probably do another ultasound in about 3 months. Glad Poppy is doing better. Chloebeaglemom Thu, 29 Mar 2012 00:00:00 GMT Buddy's Mom, I am so sorry for you loss.  I just read your post and am crying right now.  Going thru this cancer is so sad and heartbreaking.  I wish none of us had to go thru this.  I will pray for you that God will give you peace in your heart. Debbie MyPeaches Thu, 29 Mar 2012 00:00:00 GMT Hi, I'm so very sorry to hear that Buddy slipped away to the Rainbow Bridge.  I fought back the tears as I read your description of his last day with you.  It is so clear that you did everything anybody could for him, but I know that it's hard to feel that way yourself when you are grieving. It's hard to imagine what you are going through now.   I know that sometime I will have to experience it too, but it hurts to even think of it in the abstract. Please know that you are in my thoughts and prayers.  Love,  Nita (Rocky's Mom) Nita Tue, 27 Mar 2012 00:00:00 GMT Dear Buddy's Mom- I feel your pain as you let Buddy go.  Today I remember the 1 year anniversary that my baby boy, Copper, my 8 yr.old beagle had to go to Rainbow Bridge.  He, too, lost use of his hind legs.  What a significant part of our lives they become so letting them go is the hardest thing.  Please know I am with you in thought and prayer.  Hopefully Buddy and Copper are romping around together barking and howling waiting for us to arrive.  Be gentle with yourself as you grieve. Maureen (Copper's Mom) CoppersMom Tue, 27 Mar 2012 00:00:00 GMT Buddy's Mom, I am so sorry for your loss. "There but for the grace of God, go I".  I know it will be our time...sooner...later...none the less...our time will come.  I get a cold, numb feelng in my chest when I think about it. He had a wonderful five years with you...you loved him all that time and extended your love to care for him and take him to the Rainbow Bridge.  He only needed your nearness...and you fulfilled his need...for all these years and especially in the end. For Buddy.......I thank you. ChicasMom, Lynn ChicasMom Tue, 27 Mar 2012 00:00:00 GMT Hi Susan, yep i'm pretty sure it is mitoxantrone that she's on for her chemo. Poppy seems to be a bit better today, so fingers crossed that she just keeps getting better now.  Am really glad to hear that Chloe is still showing no side effects, that is very cool.  Have you had an updated ultrasound or one planned?   poppy06 Tue, 27 Mar 2012 00:00:00 GMT I'm so sorry to hear about your loss of Buddy. That must be incredibly hard to go through. My heart goes out to you. Our canine friends touch our lives in truly special ways. I know you were a blessing to each other's lives. -jenn SienasMom Tue, 27 Mar 2012 00:00:00 GMT Hello: I didn't post on here very much, maybe twice before now. But I had been reading a lot of what everyone else wrote. My beagle Buddy died last Wednesday March 21, 2012. I held in him in my arms at the vet's office as he slipped away to the Rainbow Bridge. He had done great on Piroxicam since his diagnosis in November of 2010. Buddy started to lose control of his hind legs almost 3 weeks ago, but then seemed to do well until last Monday evening. He started to lose control of his back legs again that night and had no control over them Tuesday morning. He then started to lose control of his front legs, too, and could only partially sit up. When I talked to the vet, she told me it was time, that the cancer had probably spread into either his spine or his brain. Because he wasn't in pain and would drink and eat still Tuesday evening/night, I was able to spend time just loving him before having to let him go. I made him his favorite canine casserole consisting of beef, carrots, broccoli, and rice. He ate a big bowl of it. I held him in my lap or had him right beside me all night long. About 6 a.m. Wednesday morning he started having seizures. The 3rd and final one happened right before we went to the vet's office. He responded to me some even then, but he could not move his body at all anymore. It was horrible and yet I still keep thinking I could have done something else to help him. My brother and sister-in-law were with me along with Buddy's "sister" my cocker spaniel Daisy as he left us for the Rainbow Bridge. It hurts so badly to come home and not see him, to sit on the couch and not have his head in my lap, even to not have to clean up all the stuff I had to clean up every day due to the tcc. I try to remind myself to be thankful that his decline happened quickly and he wasn't in pain, that I did all I could do for him, that I gave him an awesome life the almost five years I was priveleged to share with him (I adopted him when he was 7). It just hurts so much. BudBoysMom Mon, 26 Mar 2012 00:00:00 GMT That's really too bad that Poppy's now having a hard time.  It really is frustrating.  It just felt like the bad time wouldn't end and I wanted to kick myself for putting Bailey through it.  Even today she is a bit off.  We did manage to get in a few short walks over the weekend and her appetite was quite good.  I have an appointment with one of the surgeons at UPENN in a few weeks to discuss resecting the bladder.  Hopefully Bailey will be a candidate and we can get rid of the tumor!  I am not doing any further chemo in the meantime.  Hope Poppy gets better soon. Baileysmom97 Mon, 26 Mar 2012 00:00:00 GMT hi im new to these forums so if ive quoted you by mistake please forgive me,im not sure how to start a message. we have just found out this weekend that my cross staffi-lab of 13 yrs,has bladder cancer,we are totally beside ourselfs with worry about what is the best way forward for him. at the moment he is on metecam and also a cause of antibioatic because there was no wee in his urine just blood,which come as such a shock for us to see this,im pleased to say the infection is nearly cleared up and his urine has returned to normal,the vet has also informed us that he will stay on metecam to keep the swelling in his bladder down,he is full of life,and still loves his walks twice a day,ive now changed his diet to a low carb high protien diet,which from all the research ive been doing,this is meant to help any more tumors from forming,he will also be on vitamins as soon as i can get them,but i have to speak to the vets to make sure he can have them along side the metacam,ive always given him cod liver oil,and this is also good for them any omega 3 fatty oils are.if i can prolong his life without any pain then i will,the vet has already told his,because of his age,he propably wouldnt pull through the op to have it removed,and tbh they dont recommend it,because of were the tumors grow,i will not put him through chemo,simply because this damages other organs,and weve had those tested and they are all normal and fine,they way forward for me is change of diet,and im also looking into a vitamin called b17 which does wonders for humans with cancer but there is no evidence of what it would do to my boy. tinned dog food is full of salts and sugars,which feed the tumors so these were stopped as soon as we found out he had cancer,he is loving his new diet hes still going to the toilet properly and is totally full of beans still trying to jump on my bed,and still gets all excited when he sees his lead,or when any of us walk in the door,im not about to give up on him,after 13yrs and i will try what i can to make his time with us lots more fun lots more loving because this is what he has giving us as a family for 13yrs. flysmummy Mon, 26 Mar 2012 00:00:00 GMT Sorry to hear Poppy had a bad week after chemo. Chloe had her 4th round last week and still has never shown any side effects. She comes home, sleeps awhile and then gets up and eats like normal. Has never been nauseated that i can tell. Does Poppy take mitoxantrone for her chemo? Hope things get better for her. Will be thinking of you. Susan Chloebeaglemom Mon, 26 Mar 2012 00:00:00 GMT On Mar 25, 2012 8:29 PM Baileysmom97 wrote: Finally after 11 days of just being miserable, Bailey is almost back to her normal self.  We were able to go for short walks the past 2 days and her appetite has returned.  With everything I have heard from others, I never expected this to be so hard on her.  I have decided I am not interested in pursuing chemo any further and will be scheduling with a Surgeon at UPENN to see if we will be able to remove this tumor.  I also looked into the Salvestrols and had actually started Bailey on them before the chemo.  However, she was only on them for a short time so I just don't know if they had any effect.  I will continue with them now up until the surgery so if anything changes, I will definitely post.Sorry to hear Bailey had such a bad run, am pleased that surgery may be an option for you, will keep my fingers crossed! Poppy's had a really bad run on chemo this past week, they will be giving her an anti-nausea injection next time, so i am hoping that will make things better for her. I really want to give the high dose vitamin c a go, but will wait till she comes right from this chemo round. So frustrating to see her feeling so sorry for herself, managing to keep her eating, shes off her normal food but chicken and cheese still gets er excited. poppy06 Mon, 26 Mar 2012 00:00:00 GMT Yes, my dog Shelby's tumor was expelled in her urine after several months of treatment with Neoplasene.  You can read my posts on this blog which give all the details but if you need anything more, please do not hesitate to contact me in a private message.  Good luck to you.   Shelbysmom2 Mon, 26 Mar 2012 00:00:00 GMT Hi there, My beautilful border collie, Siena, most likely has TCC. We are supposed to receive pathology reports tomorrow from the biopsies. I really don't want to go the chemo/radiation route. I have a friend who has been educating me about high dose Vitamin C. Did you try it yet and did you have any good results? I'm also weighing Neoplasene, insulin with low doses of chemo and photodynamic therapy.  If anyone has experience (good or bad) with these treatments or other holistic options, I'd be so appreciative if you'd share it. Trying to sort through all the information out there can be overwhelming. Thank you. SienasMom Mon, 26 Mar 2012 00:00:00 GMT On Feb 01, 2012 4:43 PM Baileysmom97 wrote: Bailey & Karin (Baileysmom97), New JerseyHi, My name is Christine and my dog bailey has bladder/urethra cancer. We live in NY and I was wondering if you know the best oncologists/Vet hospitals for canine bladder cancer in the NY NJ PA area. Any advice is greatly appreciated! Thank you!! bailey661 Mon, 26 Mar 2012 00:00:00 GMT On Feb 01, 2012 4:43 PM Baileysmom97 wrote: Bailey & Karin (Baileysmom97), New JerseyHi My dog Bailey has bladder cancer and we live in NY. I was wondering if you know the best oncologists in the NY, NJ, even PA area. Any advice is greatly appreciated!!  thank you!! Christine bailey661 Mon, 26 Mar 2012 00:00:00 GMT Finally after 11 days of just being miserable, Bailey is almost back to her normal self.  We were able to go for short walks the past 2 days and her appetite has returned.  With everything I have heard from others, I never expected this to be so hard on her.  I have decided I am not interested in pursuing chemo any further and will be scheduling with a Surgeon at UPENN to see if we will be able to remove this tumor.  I also looked into the Salvestrols and had actually started Bailey on them before the chemo.  However, she was only on them for a short time so I just don't know if they had any effect.  I will continue with them now up until the surgery so if anything changes, I will definitely post. Baileysmom97 Sun, 25 Mar 2012 00:00:00 GMT The chemo has been a rough go.  Bailey has been eating, but she is far from her usual happy and active self.  I don't think I will continue with the chemo.  It was interesting to note that when I was at my local vet's office, the Dr. told me that they just recently brought in a Board Certified Surgeon to operate on her mom's dog with TCC.  Bailey's tumor is actually in a good area, so I am not looking into that possibility.  Bailey's specialist wasn't too keen on doing this as it could seed the tumor into other areas.  I think I might be willing to take this risk. Baileysmom97 Mon, 19 Mar 2012 00:00:00 GMT Just want to say thank you for the good wishes and support...it definitely helps!  I am just so happy that Bailey seems to be recovering from the chemo.  I guess now we'll just have to watch the blood count. Baileysmom97 Fri, 16 Mar 2012 00:00:00 GMT Great news!!! I will let u know what i notice about poppy after her next chemo on tuesday, since she's been so good the last week i will see any small differences poppy06 Fri, 16 Mar 2012 00:00:00 GMT Hi- So glad to know she's eating again!  I'm Rocky's MOm , have been following your posts for a long time and was sad to hear about her appetite loss after she has been doing so well.  Hope things continue to go well. Nita Fri, 16 Mar 2012 00:00:00 GMT Finally the appetite has returned!  It was about 72 hours after the first dose of chemo.  Hopefully she will continue to eat. Baileysmom97 Fri, 16 Mar 2012 00:00:00 GMT Hi Esther--Bailey never really had problems with the piroxicam, although there was a short time we think she was developing an ulcer.  However, the oncologist took her off the piroxicam because we are going to switch her to meloxicam (metacam is the same thing I found out) but before that can happen the piroxicam needs to be "washed out" of her system.  So right now she is not actually on anything.  Bailey ate the night of her chemo but has not eaten since.  I even went to our regular vet for an injection of cerenia to help with nausea but so far it hasn't helped.  I'm hoping that perhaps she will eat later on.  I read online that the nausea might go away after 72 hours. It's just so sad right now.  Throughout the entire last year you would never have known anything was wrong.  I'm just not sure she can tolerate the chemo.  I'm also waiting to discuss with her regular doctor about surgery to remove the tumor.  My regular vet just had this done with her mom's dog and has so far the dog has done well eventhough it is an older dog.  I think I'm willing to take the risk as far the tumor seeding into the body, but what I'm not sure about is Bailey's age and strength at this point.   I'm so glad that Poppy is doing well.  Continued good luck to you!  Karin Baileysmom97 Fri, 16 Mar 2012 00:00:00 GMT On Mar 14, 2012 5:12 PM Baileysmom97 wrote: On Mar 09, 2012 7:15 AM poppy06 wrote: On Mar 02, 2012 7:54 PM Baileysmom97 wrote: On Mar 01, 2012 7:30 AM poppy06 wrote: Thanks for your reply Susan, Poppy sounds very much like Chloe! We have only had a couple of bad days when she's had a pretty horrible infection, and other than that you would never know there was anything wrong with her! I'm very thankful for this board as one of the hardest things i have found is a lack of information around TCC (even her vet is having to talk to other vets for information etc) and I want to feel like I am doing everything that I can so that I never have any regrets.  We live in NZ and I haven't heard any mention of the heat treatment, which I find interesting so I will be talking to her vet about this.  I have heard things around high doses of vitamin C (1000mg of low acid vitamin C per 7kgs) having effect - which I will be doing now that I know she has had no side effects from the drugs she's on.  Also, have made our house as toxin free as I can, switching to natural cleaning products, all natural foods and fresh spring and filtered water.  Doing these things have helped me feel positive especially since I am taking some control.  Will keep on posting updates on how Poppy is responding, and am keen to hear how Chloe is doing. Hi Esther-- Could you tell me how Poppy has been since she's had the chemo.  My dog Bailey has been doing great for about a year.  We had an ultrasound yesterday and it is showing that the  tumor is starting to spread within the walls of the bladder.  I originally did not want to do chemo but I am now considering it.  Any advice you could give me would be great. KarinHi Karin, Just an update on Poppy's response to chemo, we had the results back from the blood work and her white cell count has dropped below normal, so if this doesn't go back up they may reduce the dosage. Poppy vomited a couple of times and had blood in her urine before the blood tests, but i'm pretty sure that this was an infection, so I asked to put her on some antibiotics and within 8 hours or so she was her normal happy self again.  So from this, i'd probably recommend that you ask for a course of antibiotics at the same time, so that if Bailey develops an infections, you don't have to go back to the vet.  Every visit we do to the vets from now on, if I don't have an antibiotic supply at home for her, i'll be asking for some.  Hope this gives you a bit more information and I hope Bailey's first session goes well.Hi Esther--Bailey got her first dose of chemo yesterday and already today is not feeling well.  Did Poppy have any reactions right after?  It sounds like Poppy was pretty much back to normal pretty quickly.  Bailey just wants to sleep and has no interest in food.  I'm just really worried that this may have been too much for her.  I have a call into the oncologist to see what they have to say. They gave me anti-biotics not so much for a uti but more so against an infection she may develop because of a weakened immune system.  Also, we will be switching to metacam instead of the piroxicam to see if that will work better.Hey karin, Poppy seemed fine straigh after the chemo but about a week after she was a bit crook and had blood in her urine but she responded well to antibiotics. The piroxicam made her a bit nauseous but she only vomited a couple of times over a week, was off her food on and off for a few days and she seemed to come right pretty quick so not enough for me to be massively concerned. Because of the vets recommendation of course of treatment i was pretty keen to stick to it and she now seems to have built up a tolerance to it. Shes been on the piroxicam now for just over 3 weeks and is due for her 2nd round of chemo on tuesday. She has been very very well over the last couple of days and in hindsight it has probably been over 2 months since i've seen her like this. Shes excited when she sees me, very interested in food, has had no blood in her urine for well over a week, no straining and the frequency of her going is right down to normal, she just seems very tired all the time. In the last couple of months we've had some very bad days where i've wondered if i'm doing right by her, which i'm not sure is from the drugs or from the cancer itself. It is very much a roller coaster and i'm taking one day at a time. Nothing has made been bad enough for me to ask the vets to switch or stop and i'm very keen to see the results of her first ultrasound, which will be a few weeks away. What symptoms is bailey getting from the piroxicam? poppy06 Fri, 16 Mar 2012 00:00:00 GMT The NSAID will be Meloxicam, not Metacam. Baileysmom97 Wed, 14 Mar 2012 00:00:00 GMT On Mar 09, 2012 7:15 AM poppy06 wrote: On Mar 02, 2012 7:54 PM Baileysmom97 wrote: On Mar 01, 2012 7:30 AM poppy06 wrote: Thanks for your reply Susan, Poppy sounds very much like Chloe! We have only had a couple of bad days when she's had a pretty horrible infection, and other than that you would never know there was anything wrong with her! I'm very thankful for this board as one of the hardest things i have found is a lack of information around TCC (even her vet is having to talk to other vets for information etc) and I want to feel like I am doing everything that I can so that I never have any regrets.  We live in NZ and I haven't heard any mention of the heat treatment, which I find interesting so I will be talking to her vet about this.  I have heard things around high doses of vitamin C (1000mg of low acid vitamin C per 7kgs) having effect - which I will be doing now that I know she has had no side effects from the drugs she's on.  Also, have made our house as toxin free as I can, switching to natural cleaning products, all natural foods and fresh spring and filtered water.  Doing these things have helped me feel positive especially since I am taking some control.  Will keep on posting updates on how Poppy is responding, and am keen to hear how Chloe is doing. Hi Esther-- Could you tell me how Poppy has been since she's had the chemo.  My dog Bailey has been doing great for about a year.  We had an ultrasound yesterday and it is showing that the  tumor is starting to spread within the walls of the bladder.  I originally did not want to do chemo but I am now considering it.  Any advice you could give me would be great. KarinHi Karin, Just an update on Poppy's response to chemo, we had the results back from the blood work and her white cell count has dropped below normal, so if this doesn't go back up they may reduce the dosage. Poppy vomited a couple of times and had blood in her urine before the blood tests, but i'm pretty sure that this was an infection, so I asked to put her on some antibiotics and within 8 hours or so she was her normal happy self again.  So from this, i'd probably recommend that you ask for a course of antibiotics at the same time, so that if Bailey develops an infections, you don't have to go back to the vet.  Every visit we do to the vets from now on, if I don't have an antibiotic supply at home for her, i'll be asking for some.  Hope this gives you a bit more information and I hope Bailey's first session goes well.Hi Esther--Bailey got her first dose of chemo yesterday and already today is not feeling well.  Did Poppy have any reactions right after?  It sounds like Poppy was pretty much back to normal pretty quickly.  Bailey just wants to sleep and has no interest in food.  I'm just really worried that this may have been too much for her.  I have a call into the oncologist to see what they have to say. They gave me anti-biotics not so much for a uti but more so against an infection she may develop because of a weakened immune system.  Also, we will be switching to metacam instead of the piroxicam to see if that will work better. Baileysmom97 Wed, 14 Mar 2012 00:00:00 GMT Yes, very good news indeed. I'm not blaming the vet, TCC is difficult to diagnose for a non-specialist. The last few days have been a nightmare, and I can only imagine what you go through for months. Don't give up hope, it has been cured in at least 2 cases including yours. What I can judge from the literature, they now got much better knowledge of how the cancer operates. So there are new drugs becoming available that target cancel cells only. One method I expect will be common for many cancer types is photodynamic treatment. Take care. fredrikw Sat, 10 Mar 2012 00:00:00 GMT That is such wonderful news! I'm so happy for you! It makes my day. I hope Tarzan recovers quickly from the surgery and things will be back to normal for you both. Shelby had a biopsy so I know her diagnosis is correct but it does show not to trust an assumption by the vets. Sometimes the news is much better than expected. Thankfully the Neoplasene seems to have worked for Shelby and thankfully Tarzan is cancer free! I wish this could be true for all of them. Take care and give Tarzan an extra dog treat! Shelbysmom2 Sat, 10 Mar 2012 00:00:00 GMT On Mar 08, 2012 4:53 PM fredrikw wrote: Incredible news! When Tarzan was opened a blockage was discovered and was removed with simple saline solution. There was no sign of any cancer or even alteration of the bladder. So you can say that I'm a very lucky dog owner right now! And I've learned a lot about dog cancer the last few days, thanks for the support. Lesson learned: don't trust the vet diagnosis. Take care. FredrikI would like to thank everyone that sent prayers and warm wishes for my Bella after her diagnosis in late January. I took her to a different vet for a second opinion on treatment of her TCC and through his testing and research into Bella's case, he suspected that she was misdiagnosed just as it seems Tarzan was. She went in for surgery and they found that her "tumor" was actually 4 very large bladder stones. She is doing wonderful! Although I feel very lucky and foutunate that Bella is healthy, my heart goes out to all of you that are truly dealing with this disease. I will keep you all in my thoughts and prayers and again, thank you to everyone who provided me with advice and support. Fredrikw, I second that: "don't trust the vet diagnosis", keep searching for information and treatment options for your pet! BellasMommy Fri, 09 Mar 2012 00:00:00 GMT Thanks for the update on Poppy.  We have our appointment on Tuesday so we'll see how it goes.  Bailey finished six weeks of marbofloxacin for a uti and thankfully the culture last week showed it was gone.  Bailey has a hard time on the anti-biotics so if she doesn't need them, I would rather not.  I have her on cranberry tablets so I am hoping that will keep the bacteria from causing an infection.  Esther--do you know what chemo drug they are using? Baileysmom97 Fri, 09 Mar 2012 00:00:00 GMT Esther, my oncologist won't give any antibiotics unless they do a culture to see what it is sensitive too. Right now she has been on clavamox for about a month. Glad Poppy is doing better. Chloebeaglemom Fri, 09 Mar 2012 00:00:00 GMT On Mar 02, 2012 7:54 PM Baileysmom97 wrote: On Mar 01, 2012 7:30 AM poppy06 wrote: Thanks for your reply Susan, Poppy sounds very much like Chloe! We have only had a couple of bad days when she's had a pretty horrible infection, and other than that you would never know there was anything wrong with her! I'm very thankful for this board as one of the hardest things i have found is a lack of information around TCC (even her vet is having to talk to other vets for information etc) and I want to feel like I am doing everything that I can so that I never have any regrets.  We live in NZ and I haven't heard any mention of the heat treatment, which I find interesting so I will be talking to her vet about this.  I have heard things around high doses of vitamin C (1000mg of low acid vitamin C per 7kgs) having effect - which I will be doing now that I know she has had no side effects from the drugs she's on.  Also, have made our house as toxin free as I can, switching to natural cleaning products, all natural foods and fresh spring and filtered water.  Doing these things have helped me feel positive especially since I am taking some control.  Will keep on posting updates on how Poppy is responding, and am keen to hear how Chloe is doing. Hi Esther-- Could you tell me how Poppy has been since she's had the chemo.  My dog Bailey has been doing great for about a year.  We had an ultrasound yesterday and it is showing that the  tumor is starting to spread within the walls of the bladder.  I originally did not want to do chemo but I am now considering it.  Any advice you could give me would be great. KarinHi Karin, Just an update on Poppy's response to chemo, we had the results back from the blood work and her white cell count has dropped below normal, so if this doesn't go back up they may reduce the dosage. Poppy vomited a couple of times and had blood in her urine before the blood tests, but i'm pretty sure that this was an infection, so I asked to put her on some antibiotics and within 8 hours or so she was her normal happy self again.  So from this, i'd probably recommend that you ask for a course of antibiotics at the same time, so that if Bailey develops an infections, you don't have to go back to the vet.  Every visit we do to the vets from now on, if I don't have an antibiotic supply at home for her, i'll be asking for some.  Hope this gives you a bit more information and I hope Bailey's first session goes well. poppy06 Fri, 09 Mar 2012 00:00:00 GMT Fredrik, that is wonderful news. I know you have to be so relieved to go from thinking the worst to having everything turn out so good. Happy for you and Tarzan! Chloebeaglemom Fri, 09 Mar 2012 00:00:00 GMT On Mar 08, 2012 2:06 PM fredrikw wrote: Thanks for your sympathy, Lynn, it helps a lot. I lost my previous mini sch 2 years ago and know very well the pain and sorrow afterwards. But we're not there yet, and the most important thing now is my boy's quality of life. I'm going to get him back in an hour, we'll see. It was a big op since they opened his stomach. I've opened a reference about cancer at Diigo here, where I collect all material I find. http://www.diigo.com/user/dogtcc "" target="_blank" rel="nofollow">http://www.diigo.com/user/dogtcc " target="_blank" rel="nofollow">http://www.diigo.com/user/dogtcc Take care. Fedrik, You have a good collection of resources that I enjoyed reading. Seems like all I do is sit and do research on TCC. When Chloe goes for chemo I always show up with a new list of questions for the oncologist. Will be thinking of you and hoping for the best with Tarzan. Susan Chloebeaglemom Thu, 08 Mar 2012 00:00:00 GMT Fredrik, I am so happy for Tarzan and you.  My prayers for you  (both) were MORE than answered. Give the little guy a hug for us.  Many happy days ahead for you.......enjoy. I am glad someone on this blog got wonderful news....it's about time. ChicasMom, Lynn ChicasMom Thu, 08 Mar 2012 00:00:00 GMT Incredible news! When Tarzan was opened a blockage was discovered and was removed with simple saline solution. There was no sign of any cancer or even alteration of the bladder. So you can say that I'm a very lucky dog owner right now! And I've learned a lot about dog cancer the last few days, thanks for the support. Lesson learned: don't trust the vet diagnosis. Take care. Fredrik fredrikw Thu, 08 Mar 2012 00:00:00 GMT Thanks for your sympathy, Lynn, it helps a lot. I lost my previous mini sch 2 years ago and know very well the pain and sorrow afterwards. But we're not there yet, and the most important thing now is my boy's quality of life. I'm going to get him back in an hour, we'll see. It was a big op since they opened his stomach. I've opened a reference about cancer at Diigo here, where I collect all material I find. http://www.diigo.com/user/dogtcc Take care. fredrikw Thu, 08 Mar 2012 00:00:00 GMT On Mar 08, 2012 11:10 AM fredrikw wrote: Traumatic catherization is not available in Sweden according to the vet. So they're doing a fullscale operation as we speak to take out biopsis in the cell wall. The tumor is apparently "big". It'll be a week before the pathology report comes. I'm not hopeful. Meanwhile, I'm checking out what's going on in human TCC research. Due to low funding nothing much seems happening. The prognosis for human TCC is much better, since they can operate.Fredrik, Don't give up hope. Our little creatures are much stronger than we give them credit for.  I'm praying for you.....both. Even here in the states...you have to travel around for procedures (veterinary) because of low funding. We do the best we can, with what is offered at the time.  All we can do is...our best. ChicasMom, Lynn ChicasMom Thu, 08 Mar 2012 00:00:00 GMT Traumatic catherization is not available in Sweden according to the vet. So they're doing a fullscale operation as we speak to take out biopsis in the cell wall. The tumor is apparently "big". It'll be a week before the pathology report comes. I'm not hopeful. Meanwhile, I'm checking out what's going on in human TCC research. Due to low funding nothing much seems happening. The prognosis for human TCC is much better, since they can operate. fredrikw Thu, 08 Mar 2012 00:00:00 GMT I found this helpful article: http://dogtime.com/urinary-bladder-cancer-canine-cancer-libr They really need to find a cure, fast. This is not acceptable. fredrikw Wed, 07 Mar 2012 00:00:00 GMT yes, I'll make sure that the procedure is without risk. Problem is they can't see the tumor on their ultrasound, and they need to "stage" it, i.e. find out location, size, if it's spreading etc. But I'll check with the oncologist what the correct procedure is. thanks, Fredrik fredrikw Wed, 07 Mar 2012 00:00:00 GMT On Mar 07, 2012 7:26 AM fredrikw wrote: Been reading this board now, very useful information. My mini schnautzer is only 3 so the prel diagnosis was a real shock 2 days ago. I'm still in a shock but has now started to act. Tomorrow they'll open him up to take a biopsy for analysis, and also get more info on the tumor. He's had all the usual symptoms and the vet seems pretty sure that it's inoperable TCC so that's what I assume. I've started to read all the sci articles I can find and has booked an appointment with an oncologist at our national vet university. The only supposed cure I've found is the neoplasme treatment, if it's not spam that is. All other studies from Purdue univ shows extension of life with about a year. This is not acceptable with the knowledge level they now have about cancer cells, even down to the DNA level. One "promising" technique is to use photoactive substances, i.e particles filled with drugs, that assemble in the cancer cells. Then they're activated by light and kills only the cancer cells. That's what I know right know. Take care, this is pure torture on our souls.Hi "fredrikw", "Opening him up" is not the best way of getting a biopsy when TCC is a consideration. "Traumatic catherization" gets the biopsy you need for DX, and does not give the TCC a chance for metastasis. Has a veterinary oncologist suggested the surgery route for DX?  I would question this, not the best for a 3 year old mini schnauzer. My pet Chica was DXed with the traumatic catherization in July 2009.  I was happy that I found the information not to use surgery for DX of TCC (the original vet suggested it and I researched and found that it was not good to do surgery and I declined and requested a referral to veterinary oncology, who did the traumatic catherization).  I feel I made the right decision for my pet, she was only 6 years old at the time. I see you have booked an appointment with an oncologist (don't know what university, but most of the time they are very good), please wait until you get to see him/her before you consider surgery for DX for your pet. I wish you all the best. ChicasMom Wed, 07 Mar 2012 00:00:00 GMT Ok, thanks. I'll convey the info to my oncologist. regards, Fredrik fredrikw Wed, 07 Mar 2012 00:00:00 GMT Fredrikw I'm serious about the Neoplasene getting rid of my Shelby's tumor.  The story I posted is not spam.  My vet called the people at Buck Mountain and discussed how to administer this treatment when I brought the printout from this blog to her back in Aug.  After 5 months of treatment Shelby's tumor is gone! Please ask your vet to check this out and if he/she wants to talk to my vet her name is Kathy Mitchener and her phone number is 901-385-9172.  We are in the Memphis area.  Your dog is so young that this might be a great option.  I'm so sorry for you and all those who are dealing with this but that is why I'm posting about this treatment. It's an herbal treatment so some vets may not want to deviate from the mainstream and try it.  Also, your dog needs to be a grain free and low, low carb diet.  Grains and carbs feed the tumor.  Shelby eats nothing but rotisserie chicken from Costco mixed with green beans and her supplements (probiotic, greek yogurt, etc).  I sincerely hope this helps.     Shelbysmom2 Wed, 07 Mar 2012 00:00:00 GMT Been reading this board now, very useful information. My mini schnautzer is only 3 so the prel diagnosis was a real shock 2 days ago. I'm still in a shock but has now started to act. Tomorrow they'll open him up to take a biopsy for analysis, and also get more info on the tumor. He's had all the usual symptoms and the vet seems pretty sure that it's inoperable TCC so that's what I assume. I've started to read all the sci articles I can find and has booked an appointment with an oncologist at our national vet university. The only supposed cure I've found is the neoplasme treatment, if it's not spam that is. All other studies from Purdue univ shows extension of life with about a year. This is not acceptable with the knowledge level they now have about cancer cells, even down to the DNA level. One "promising" technique is to use photoactive substances, i.e particles filled with drugs, that assemble in the cancer cells. Then they're activated by light and kills only the cancer cells. That's what I know right know. Take care, this is pure torture on our souls. fredrikw Wed, 07 Mar 2012 00:00:00 GMT Just to let you all know that my dog Shelby was diagnosed in August 2011 with TCC.  I read on this blog about Neoplasene.  I found a holistic vet in the area and she really opened my eyes about the type of diet Shelby should be on, the supplements and when I brought up Neoplasene she was willing to try it.  She was not willing to do the infusion method as mentioned on the Buck Mountain Botanicals website (Dr. Fox) but she put Shelby on an oral dose.  Things went along without incident until January 2012.  Then one day Shelby urinated a large puddle in the kitchen and it was full of blood and something that looked like clots.  I thought for sure her cancer had worsened.  When I took her 2 weeks later for her regular ultrasound, the vet was amazed to find that her tumor was completely gone!  Yes, I mean completely!!!  Today, she went back for another ultrasound (its been 7 weeks) and the tumor is still gone!  She is feeling good and acting like her old self again!  Please, please find a holistic vet and give this Neoplasene a try.  She is also on Piroxicam twice a week.  If anyone would like more information from me, please feel free to email me Message edited by CancerCompass staff. For personal protection,email address removed. Consider private reply. Please review CancerCompass Member Guidelines athttp://www.cancercompass.com/common/guidelines.html  !! But know there is hope out there!  Shelby is going to be 14 in April.  My vet is so excited about this treatment (Shelby was the first dog she tried on it), she would be happy to talk to anyone's vet who wants more info too Shelbysmom2 Wed, 07 Mar 2012 00:00:00 GMT Just to let you all know that my dog Shelby was diagnosed in August 2011 with TCC.  I read on this blog about Neoplasene.  I found a holistic vet in the area and she really opened my eyes about the type of diet Shelby should be on, the supplements and when I brought up Neoplasene she was willing to try it.  She was not willing to do the infusion method as mentioned on the Buck Mountain Botanicals website (Dr. Fox) but she put Shelby on an oral dose.  Things went along without incident until January 2012.  Then one day Shelby urinated a large puddle in the kitchen and it was full of blood and something that looked like clots.  I thought for sure her cancer had worsened.  When I took her 2 weeks later for her regular ultrasound, the vet was amazed to find that her tumor was completely gone!  Yes, I mean completely!!!  Today, she went back for another ultrasound (its been 7 weeks) and the tumor is still gone!  She is feeling good and acting like her old self again!  Please, please find a holistic vet and give this Neoplasene a try.  She is also on Piroxicam twice a week.  If anyone would like more information from me, please feel free to email me Message edited by CancerCompass staff. For personal protection,email address removed. Consider private reply. Please review CancerCompass Member Guidelines athttp://www.cancercompass.com/common/guidelines.html  !! But know there is hope out there!  Shelby is going to be 14 in April.  My vet is so excited about this treatment (Shelby was the first dog she tried on it), she would be happy to talk to anyone's vet who wants more info too Shelbysmom2 Wed, 07 Mar 2012 00:00:00 GMT On Mar 06, 2012 9:38 PM karincam1 wrote: My Huey had his ultrasound today, big mass neck of the bladder. Vet gave weeks to months. I am so sad today. Good luck with your girl. I pray she has a great response.  Karin, I am so sorry for the news you just got.  I know how horrible and heartbreaking it is.  I will never forget the date I got the news... June 1, 2010.  They gave my baby 6-12 months at that time.  We are going on 2 years now!  So keep your chin up.... their timing is not always accurate.  I don't even think vets should take that guess.  It makes it harder, I think.  I pray alot which helps both of us.  I also learned to be positive in front of Peaches and not cry in front of her.  She picks up on my sadness and it doesn't help her.  I will say a prayer for Huey, and you.  Just do the best you can do to keep her happy and comfortable. Debbie MyPeaches Wed, 07 Mar 2012 00:00:00 GMT How about a beagle Mix? Are they more protected from this type of cancer?So many mix breeds that need homes. karincam1 Tue, 06 Mar 2012 00:00:00 GMT Just read your story. I don't blame you for your feelings. My dog was just diagnosed, he is 12. Big, and 12, still plays ball, but I know it will soon come to an end. I am happy I got 12 years with him. I am sorry for your loss. Don't stay heartbroken. Rescue a dog in need, save a life. it will heal your heart, and save a life. karincam1 Tue, 06 Mar 2012 00:00:00 GMT My Huey had his ultrasound today, big mass neck of the bladder. Vet gave weeks to months. I am so sad today. Good luck with your girl. I pray she has a great response.   karincam1 Tue, 06 Mar 2012 00:00:00 GMT On Mar 06, 2012 2:57 AM karincam1 wrote: 2 Karins? What are the odds. My dog's name is Huey, he is 12. Such a sweet little man.Maybe we should both play the lottery! My girl, Bailey turned 14 in December and we'll be starting  chemo next week.  I am hoping for the best! Baileysmom97 Tue, 06 Mar 2012 00:00:00 GMT 2 Karins? What are the odds. My dog's name is Huey, he is 12. Such a sweet little man. karincam1 Tue, 06 Mar 2012 00:00:00 GMT My 12 year old Pit Chow mix is straining, and having frequency with just drops, blood in urine. Going for ultrasound in AM. I hate to think of him leaving me. I feel for you, and hope you are getting along. Prayers for you and your baby.... Karin karincam1 Tue, 06 Mar 2012 00:00:00 GMT On Mar 03, 2012 8:14 AM poppy06 wrote: Hi Karin, Poppy had absolutely no side effects from the chemo. You would never know she'd had a round of it and that shes on any other medication. She is playing, eating and very happy. She had baseline blood tests at the sametime and has another lot on wednesday to make sure it's not doing any damage to her bone marrow i think, so i can let you know a bit more then, but based on what poppy has been like i have no hesitation saying go for it. It's really encouraging for me to hear that Bailey has been doing great for a year too, as it gives me hope for poppy's journey. Let me know how you get on :)Thanks so much for the info.  It makes me feel a bit more at ease about putting her through this.  When she was first diagnosed about a year ago, I had decided against chemo.  Now, with such encouraging stories I think it is definitely worth trying to see if we can stop the tumor from spreading.  I have her scheduled for next week and will post after that. Karin Baileysmom97 Mon, 05 Mar 2012 00:00:00 GMT Hi, where did you find this graviola? regards, Fredrik fredrikw Mon, 05 Mar 2012 00:00:00 GMT Hi Karin, Poppy had absolutely no side effects from the chemo. You would never know she'd had a round of it and that shes on any other medication. She is playing, eating and very happy. She had baseline blood tests at the sametime and has another lot on wednesday to make sure it's not doing any damage to her bone marrow i think, so i can let you know a bit more then, but based on what poppy has been like i have no hesitation saying go for it. It's really encouraging for me to hear that Bailey has been doing great for a year too, as it gives me hope for poppy's journey. Let me know how you get on :) poppy06 Sat, 03 Mar 2012 00:00:00 GMT On Mar 01, 2012 7:30 AM poppy06 wrote: Thanks for your reply Susan, Poppy sounds very much like Chloe! We have only had a couple of bad days when she's had a pretty horrible infection, and other than that you would never know there was anything wrong with her! I'm very thankful for this board as one of the hardest things i have found is a lack of information around TCC (even her vet is having to talk to other vets for information etc) and I want to feel like I am doing everything that I can so that I never have any regrets.  We live in NZ and I haven't heard any mention of the heat treatment, which I find interesting so I will be talking to her vet about this.  I have heard things around high doses of vitamin C (1000mg of low acid vitamin C per 7kgs) having effect - which I will be doing now that I know she has had no side effects from the drugs she's on.  Also, have made our house as toxin free as I can, switching to natural cleaning products, all natural foods and fresh spring and filtered water.  Doing these things have helped me feel positive especially since I am taking some control.  Will keep on posting updates on how Poppy is responding, and am keen to hear how Chloe is doing. Hi Esther-- Could you tell me how Poppy has been since she's had the chemo.  My dog Bailey has been doing great for about a year.  We had an ultrasound yesterday and it is showing that the  tumor is starting to spread within the walls of the bladder.  I originally did not want to do chemo but I am now considering it.  Any advice you could give me would be great. Karin Baileysmom97 Fri, 02 Mar 2012 00:00:00 GMT Thanks for your reply Susan, Poppy sounds very much like Chloe! We have only had a couple of bad days when she's had a pretty horrible infection, and other than that you would never know there was anything wrong with her! I'm very thankful for this board as one of the hardest things i have found is a lack of information around TCC (even her vet is having to talk to other vets for information etc) and I want to feel like I am doing everything that I can so that I never have any regrets.  We live in NZ and I haven't heard any mention of the heat treatment, which I find interesting so I will be talking to her vet about this.  I have heard things around high doses of vitamin C (1000mg of low acid vitamin C per 7kgs) having effect - which I will be doing now that I know she has had no side effects from the drugs she's on.  Also, have made our house as toxin free as I can, switching to natural cleaning products, all natural foods and fresh spring and filtered water.  Doing these things have helped me feel positive especially since I am taking some control.  Will keep on posting updates on how Poppy is responding, and am keen to hear how Chloe is doing.  poppy06 Thu, 01 Mar 2012 00:00:00 GMT Hi Esther, sorry you have this dreaded disease too. Back in Oct. when I would try to take Chloe for a walk she would have to stop and pee continuously. The vet would do a culture and put her on an antibiotic. Still lots of squatting to pee. They would do another culture and try a different antibiotic. This went on for 2 and 1/2 months. I would see some blood occasionly. Finally on Jan.. 2nd we had an ultrasound done and the oncologist showed me the tumor in her bladder. It was in the trigone area. This Dr. taught at the University of TN vet. Hospital and had started working at the pet emergency where he does the chemo treatments. He also does a heat treatment called hyperthermia that puts heat at her bladder area for 60 minutes. It is supposed to kill cancer cells. We had been doing that once every week and chemo every third week. They did have to sedate her for the heat treatments because she needed to lay flat on the pad and she just wouldn't be still. She has acted fine and even gained 3 lbs. She still squats to pee often when when she goes out. That has not changed. We had the 3rd chemo last Thursday and also another ultrasound. It did show that the tumor had shrunk some. The Dr. has recommended staying on the meloxicam and having chemo and 1 heat treatment together every four weeks. She also is on clavamox for 1 month because of another bladder infection. He said he would check her urine about a week after she finishes up the clavamox. Chloe seems happy and you would not know anything was wrong with her unless you saw her peeing. She doesn't have accidents in the house and really does not have to go out that often during the day. If the tumor continues to grow and stops her from peeing there is the decision about stents which Is costly or he said he could put a port in(or something like that) ithat would go from her bladder to her stomach wall and I would drain it 3 or 4 times a day with a syringe. Her quality of life seems good. Because of the expenses we may decide later on just chemo or just the heat treatments not both. Then have ultasounds done to see how things are changing. I know there will be lots of decisions in the coming months. I just try to stay focused on how things are right now and not think about what the future may bring. Let me know how things are going with Poppy. All we can do is try to help and encourage each other. Will be thinking of you and waiting to hear how Poppy is doing. Susan, Chloe' mom Chloebeaglemom Wed, 29 Feb 2012 00:00:00 GMT On Feb 11, 2012 2:54 AM Chloebeaglemom wrote: Hi Karen, Emily and Murphy, my 8 yr old beagle was diagnosed with TCC on Jan. 2. We also decided to do chemo which is every 3 weeks. I have not seen any side effects. She has had 2 rounds and will do another ultrasound after the next chemo treatment to see if the tumor has shrunk any. She also takes meloxicam instead of the piroxicam. I think it's supposed to be easier on the stomach. I changed her food to the Blue buffalo wilderness salmon, but she is mostly eating cooked chicken, green beans, broccoli, eggs and lean cooked beef. Hope every thing goes well for Emily. Will be thinking of you too! Susan, Chloe's momHi Susan, Poppy, my 7 year old Pomeranian was diagnosed two weeks ago and has just started chemo today, with the routine to be the same as you have talked about.  She is having piroxicam in addition (at this stage every two days to check) her tolerance, and I have started her on a natural food diet much like what you have mentioned.  Luckily I have seen no side effects so far!  Her initial symptoms were straining to urinate and blood patches in her urine, leading to diagnosis.  My question for you I guess, is what symptoms did Chloe initially have and what have you noticed since starting her treatments?  My decisions on treatments are based on her quality of life and not wanting her to feel pain or discomfort as much as possible (I know that this is unrealistic over the coming months\fingers crossed years!), so I am very keen to hear of what anyone can tell me around their results from treatments :).  Thoughts are with everyone! Cheers Esther poppy06 Tue, 28 Feb 2012 00:00:00 GMT I lost my dog to TCC in Aug. 2011..Do not give up..She lived a year after the diagnosis.  I wish that I would have known about the following blog when I found out, but I was at a loss as to how to proceed. That said. Dr Terrence Fox (Buck Mountain Botanicals)has been the only one reported to cure this type of cancer with neoplasene (herbal chemo) infused directly into the bladder to bring about necrosis (death of malignant cells)  .  Look on his website (Buck Mountain Botanicals) or go to a vet that subscribes to this method.  Also, go to the Dog Cancer Diet blog as nutrition is very important when it comes to any dog cancer.  My 14 year old dog died because her liver got overwhelmed with the oral neoplasene and failed because of it.  The injectied form does not have this effect..Your dog is still young and can withstand this method..They can put the neoplasene directly in the catheter..He is a brilliant man and a biochemist that has lectured on the method at numerous vet conventions...Also, do the apocaps...that canine cancer doc recommends...Much love and good wishes..God Bless, it is hard, but you must remain calm..   Cpraylo Tue, 21 Feb 2012 00:00:00 GMT My 7 year old German Shepherd Sydney was diagnosed last Friday with a urethra tumor that is blocking her urine flow, thus she cannot pee, it is stays in her bladder causing her bladder to be distended. We have spent all weekend at the regular vet and all day Sunday at the E clinic (where they were BTW amazing with her!) she had a temporary catheter put in, it dangles and basically she drips all the time - this however, is better than being backed up and becoming toxic. Pathology is still out, but DR pretty much callled it TCC. I have been looking at many posts on this site. I am intriqued by Graviola and it's positive effects. While she was having her procedure yesterday, i bought some and started her on it last night. I am hoping it will help enough to allow a little passage for her to pee on her own. We hope to hear tomorrow about the pathology report and will most likely start meds. We are opting not to do invasive surgeriese or chemo, but am interested in knowing if anyone else has a dog with a perm cath. She has been an inside and outside dog, now she is mostly outside due to the constant stream of pee. Though i am contemplating doggie diapers _ JUST AT NIGHT - so she can sleep inside on her bed where she has for 7 years. I spent 2 days crying and still do whenever i look in her face, but decided crying wasn't helping and it was time to get this mamma moving. They are litrally my kids. I am sinlge, no kids and these dogs are actually better behaved than many of my friends 2 legged kids...lol. Any advice as i dive into doing what is best for Syd is appreciated. thanks so much. many prayer for each of you, as you are facing some of the same momtosydney Tue, 21 Feb 2012 00:00:00 GMT Hi Karen, Emily and Murphy, my 8 yr old beagle was diagnosed with TCC on Jan. 2. We also decided to do chemo which is every 3 weeks. I have not seen any side effects. She has had 2 rounds and will do another ultrasound after the next chemo treatment to see if the tumor has shrunk any. She also takes meloxicam instead of the piroxicam. I think it's supposed to be easier on the stomach. I changed her food to the Blue buffalo wilderness salmon, but she is mostly eating cooked chicken, green beans, broccoli, eggs and lean cooked beef. Hope every thing goes well for Emily. Will be thinking of you too! Susan, Chloe's mom Chloebeaglemom Sat, 11 Feb 2012 00:00:00 GMT Hey all, Just thought I should share this newer web site devoted to pet cancer! It also had links to sites that are partnering dogs with cancer with clinical studies-helping in the fight against people and K-9 cancer! Be sure to look at the ABC World New report that highlights the site. http://abcnews.go.com/WNT/video/treating-cancer-dogs-kids-15 It's a nice, just not as much traffic as this one yet, so I thought I'd spread the word!! http://mycancerpet.com/ LittleKaren Fri, 10 Feb 2012 00:00:00 GMT Good,,, did they say how big her tumor was,, my sadie has had it for over 2 years, the hardest part is the straining to pee and little accidents, but for the most part she is okay.  She did lose about 6 pds . over these 2 years, but she is at a healthy weight.  We didn't do chemo, we both lost people we love to cancer and didn't want to put her through that. Fortunately the rimadyl and antibiotic has worked. They call her the miracle dog:) Best of luck, I understand your pain. Stephanie sadiemagoo Fri, 10 Feb 2012 00:00:00 GMT Hi Stephanie, They have it all down to science here as far as the radiation. It's one of their specialties. But I'm not thinking its worth the limited time it may extend her life. They said a couple of months is typical and the cost is outrageous. Chemo was not cheap, but after reading about it and because Em is so young, that was our choice. Thanks so much for letting me know! It affirms my decision to avoid it. You and Sadie take care, Karen, Emily, and Murphy LittleKaren Fri, 10 Feb 2012 00:00:00 GMT We give Em the Piroxicam in her nightly food. I get it from a compounding pharmacy and it's mixed with a chicken fat broth type liquid that she loves! We haven't had any problems and she has a little bit of a sensitive stomach. Best wishes to you and Bella! Karen, Em, and Murphy LittleKaren Fri, 10 Feb 2012 00:00:00 GMT I just Bella's picture.  She is just a darling little girl.  Rio weighs 35#, so I think your dose will be much smaller than what I give.  Again, your vet should know the dosage. Iloverio Fri, 10 Feb 2012 00:00:00 GMT I was told to give the Piroxicam at night with food (dinner time).  I give Rio misoprosatal 3X a day and omeprazole (Pepcid)  once a day (dinner time).  Misoprostal is I think an anti-inflamatory to prevent ulcers.  Rio is a Wheaten, and they usually have sensitive stomachs.  He has tolerated everything very well.  I am not sure how much your dog weighs, but the dosage will depend on that.  Buy one of those pill-cutters -- it really helps.  Your vet should advise you on the dosage.  I just give Rio his medicine mixed in with his food or after he eats.  If I fix him something like lean ground beef, salmon or chicken, he will eat the medicine mixed in just fine.  Otherwise I put it in some cheese or a pill pocket or small meatball or something.  My vet said it does not take much food to accomplish the "give with food" requirement, so I don't worry about that.  Wet dog food (all protein) also works for making the medicine more appealing.    Iloverio Fri, 10 Feb 2012 00:00:00 GMT I just gave my Bella her first dose of Piroxicam (0.95 mls every 24 hours) and can't help but worry about it causing stomach upset - she has a very sensitive tummy. I made sure to ask her vet before giving it to her & he recommended 1/8 of a 10 mg Pepcid AC once daily.  I gave her chicken and broccoli for dinner with Pepcid, waited about 30 mins and gave her the Piroxicam.  I was wondering is anyone has any helpful suggestions on their medication routines? Morning vs night for meds, is Pepcid enough?  Warmest wishes to you all, Britt & Bella BellasMommy Fri, 10 Feb 2012 00:00:00 GMT Hi Karen, It is so nice to have helpful suggestions like yours and to know that others relate to how I am feeling, although I wish none of us had to experirence this. Your Emily sounds like a great girl! Its amazing what great support they provide us with when we need it. Bella has licked my tears away so many times since her diagnosis Friday.  Sunday night I decided it was time to stop crying and try to be positive! I took Bella to the groomer, started cooking her special meals and got a second opinion from a new vet for a treatment plan. Her previous vet simply prescribed Piroxicam and sent us on our way - I didn't feel she knew much about TCC. Bella is in great spirits and is loving every day as I hope Emily is.  I'll keep you in my thoughts & thanks again, Britt BellasMommy Wed, 08 Feb 2012 00:00:00 GMT Karen, just read your post I was told radiation was not a good option at all with TCC especially in dogs because the bladder is not a stationary organ.  Basically they set up the radiation blast that area then set it up again to do the same thing later on and the bladder could have moved.  What results is possibly damaging another organ.  I also am not using piroxicam for my beagle.  I only use Rimadyl, and added Mytaki oil, it's a mushroom oil, packed full of vitamin D.  A lot of people use mytaki that are on the probiotic diet.  When I researched it it seemed beneficial.   My Sadie saw me through the deaths of both my parents.. We have battled this for over 2 years now:) h ard road at times,, if you have any questions please feel free to ask. Best of luck on your dissertation.. ARe you in education? Stephanie sadiemagoo Mon, 06 Feb 2012 00:00:00 GMT Ooops-I forgot to add, Emily, Murphy and I are in Zurich, Switzerland. LittleKaren Mon, 06 Feb 2012 00:00:00 GMT Hello BellasMommy, My Emily, beagle, is only 6 and recently diagnosed with TCC. To help me feel proactive, I bought the ebook by Dr. Damian Dressler (I found the ebook for $9.99.) and got the free Dog Cancer Diet book to help me with the food thing.  Here's the link http://www.dogcancerblog.com/  Cooking her special diet makes me feel proactive in her treatment and she loves it, so double bonus! I have no idea about any of the other supplements he recommended as I opted to go with the chemo for Emily because she is so young. I was glad I made the chemo choice for her because it did shrink her tumor to half of its original size. She did fine with the chemo with some side effects--a little more sleepy and stopped eating at one point--but the vet adjusted the treatment and I put her on Dr. Dressler's diet. Now she eats like a ...well...beagle! ;) She has not required anything with the Piroxicam. They offered radiation as an option, but I did not elect to do that. We did a biopsy, and Em's tumor is also at the top of the bladder, just at the opening of one of her ureters in the trigone area. They did the biopsy endoscopically, to be certain that it was TCC. My Em has helped me through a divorce, 3 moves, and now trying to write a dissertation! I have no children, so my maternal instincts are focused on my pups...I can relate to your feelings! We wish you and Bella the best and as was suggested to me, stay focused on keeping her happy. I take Em on lots of walks, feed her special food, give lots of cuddles and remind her of what a good girl she is! That helps me feel like I am doing what I can to help with the fight. Karen (Emily and Murphy's mom) LittleKaren Mon, 06 Feb 2012 00:00:00 GMT Nita, Thank you so much for your kind words and for keeping us in your thoughts. I will definitely take your advice and call Bella's vet tomorrow to get something for her to take for stomach upset with the Piroxicam. She has always had a sensitive tummy, so I should probably prepare myself for that. I live in central California and do not have any oncologists near me..I am researching different vet options for Bella. Although I like her current vet, I am not confident that she has much expierence with this and I want her to get the best care she can. I am sending my warmest wishes for you and Rocky and appreciate your imput.  Lynn, I am doing my best to work through being so upset and focus on starting a new week tomorrow for Bella. I think that once I feel like I am getting into a routine and being proactive for her, I will feel much better and less overwhelmed.  She is currently on Purina One Beyond..from what I know, its pretty natural but now I am thinking I should switch both her kibble and treats. Tomorrow I plan to measure out a smaller portion of kibble for the day and incorporate fresh veggies and meat into her diet for dinenr - chicken and broccoli. I'll ask her vet about the Cranadin and something to take with the Piroxicam tomorrow and also want to start the green tea ASAP.  I had to laugh when you mentioned researching with tissues within reach - that's been me for a few days now. Bella did have an ultrasound and apparently the tumor was clear as day. We discussed a biopsy but her vet didn't think it would be successful due to its location and her small size. Her vet is extremely confident in her diagnosis with the V-BTA test. I haven't heard about a traumatic catheterization..I will look into that as well.  As for an oncologist, I live in central CA and do not have one anywhere in my area. I have found a vet in a nearby city that is supposed to be very knowledgeable with cancer in dogs..I plan to take Bella there for an office visit to see what he says.  I will be thinking of you and Chica and appreciate all of your advice!  BellasMommy Mon, 06 Feb 2012 00:00:00 GMT Hi Brittany and Bella,   I am so sorry that you have to access this site, but happy that you found us. Strong…I always was, but stronger now. Educated….high school, but what I have learned since July 2009 about TCC, you could say educated (the hard way, college of hard knocks). Chica was only 6 when DXed, so I know how bummed you really feel. Once you get through the “Why my Bella (Chica)?”, you will find the strength to take her as far as SHE wants to go.   How much to feed a 7 lb. Bella. It depends on what you are feeding. I have been feeding some kibble to Chica and always have (I always have used Blue Buffalo, first organic chicken…not made anymore, then I switched to Longevity Mature). She does well on it and it only makes up a small portion of her meals. Mostly she gets home cooked food, salmon, vegetables, chicken (with her meds). Unfortunately, I had to do hit or miss for the right amount. We weight her every Monday (along with ourselves). If she is starting to move upward, we cut back some and keep her weight pretty steady. Right now Chica is at 13 lbs. and we are trying to get her back to 12 lbs. She actually LOOKS good at 12 lbs., nice waist when looking down on her and from the side and not skinny. She gained a pound when we were inTexasdoing laser ablation. We chose to get that done because she was starting to lose her “stream” of pee. A dog that can’t pee is not longed for this world and we had to do something before it was an emergency. We were there about 7 weeks in all, also doing some of the chemo that accompanies laser ablation. We came home and are finishing her chemo here at NC State Vet School.   The Cranadin is working very well. It cut down on a lot of the urgency she was having. Now she can come and get us and still make it outside. I’m still researching the green tea and mushrooms and will be adding them soon (after I run it past her oncologist).   It’s hard to get past the tears. Heck, I still cry, but not as much as I did in the beginning. I used to be researching with a box of tissues right by me, but I never gave up. Just keep on remembering you are doing all this for Bella and her comfort and crying slows you down.   Piroxicam….wonderful drug….potent on the stomach. Do something immediately when you start giving it to her. We chose misoprostol, others used sulcralfate (Carafate) with the same result. Most of us also give Pepcid according to vet instructions.   Did your vet do an ultrasound? Sometimes it’s not good to depend solely on the ultrasound and V-BTA for a diagnosis. A traumatic catheterization (a biopsy is taken without causing metastasis) would provide a definitive diagnosis and then you would know for sure what you are dealing with.   Accesshttp://petcancercenter.org, left sidebar, Locate an oncologist. This might help you in choosing an oncologist in your area. If you are near any of the Universities that have Vet School Small Animal Clinics you would probably do better (they are usually less expensive than private practice). What state are you in? We did a survey of the pet moms and we are pretty scattered. It was a light moment for a little mommy down time.   ChicasMom.Lynn   P.S.  My spell check said that a lot of my post is "fragmented".....heck.....because of this TCC most of my DAYS are fragmented....just a way of life right now. ChicasMom Mon, 06 Feb 2012 00:00:00 GMT Hi to Brittany, My name is Nita and I have a ten year old standard dachshund with tcc.  I am thinking of you and Bella- Like my vet said, this cruel disease often hits "the young kids" (I like that she calls dogs kids),  and it must be extra hard to have a dog as young as Bella diagnosed with tcc.  I was a "complete mess" too when I first heard Rocky's diagnosis.  Just know that this community is here to provide support and information.  I have received a great deal of both thru this site. I would just like to say a couple of things today, and more later.  First, you will notice that many dogs taking Piroxicam also take some stomach medicine (I'm guessing most commonly Pepsid) to prevent an upset stomach.  Rocky is now on two stomach meds because he is often on an antibiotic also.  Rocky has always had a fragile tummy, so maybe this doesn't apply to all dogs, but I think its a good idea to check with Bella's vet anyway.  Second, maybe Bella's vet could confer by phone with a vet oncologist.  There really aren't too many of these specialists in the country.  We go to one in Michigan at Oakland Veterinary Referral Services.  I know that there are good vet oncologists at Michigan State University too.  I know how very difficult this is, and my thoughts and prayers are with you and Bella.  I'm glad you found us.  As you can see from recent posts, we are from all over the country (and sometimes from other countries), so that we can face and fight this rare canine cancer together. Love, Nita   Nita Sun, 05 Feb 2012 00:00:00 GMT My name is Brittney and my 4 year old pomeranian Bella was just diagnosed with TCC this past Friday. Although she is in great spirits, I have been a total and complete mess since her diagnosis. I feel so fortunate to have found this board and wanted to introduce myself & my little one. I know that your expierences, advice and knowledge will be a great source of support and information for Bella's journey. It is so frustrating when people don't understand the pain that we are expierencing for our pets - they are not 'just dogs'. I have had many pets but never have I had a companion as special as Bella. To share a bit about us - she was a gift from my husband before we were married. I am 24 years old. Since getting married and purchasing our first home, she has completed my new family. My husband works nights and is a full time student...so we spend a lot of time together. She is the official greeter, meal moocher, home security system (or so she thinks) and my best friend.  After noticing blood in her urine 1 week ago I suspected that she had a UTI and instead received the news that she has an inoperable tumor in the neck of her bladder. Due to her small size and the tumor location, her vet did not think a biopsy was possible so she was diagnosed after taking a V-BTA test. I have ordered Piroxicam to start her on and do not want to put her through chemo. Her vet does not seem to have much expierence with TCC so in addition to me researching different vets in my area, any advice on diet, other meds, supplements etc is greatly appreciated.  Thank you and love to all. BellasMommy Sun, 05 Feb 2012 00:00:00 GMT Hi Lynn, I am new to the board and came across your advice to Barbara on Chica's diet and just had to reply - you seem like such a strong and educated person! My pomeranian Bella is only 4 years 7 months old and was just diagnosed Friday so strength and education are two things I really need to work on right now.  In regards to your post, I had no idea that certain foods can have a negative affect on her illness as I am just starting this journey and trying to research what will be best for her. Bella too will dart to the kitchen the second she hears that I am opening or making something. My attitude lately has been - if she wants it, I don't want to deprive her of anything. Guess that'll have to change! I am having a difficult time figuring out portions for her diet. Bella only weights about 7 lbs. How much does Chica weigh? All I really know so far is that Bella will start Piroxicam next week. I would like more info on green tea, Cranadin, etc. It's all just so overwhelming!  Thank you for sharing what has worked for you and Chica. I hope that I too can get past the tears and get Bella on a routine to make the most of my time with her.  BellasMommy Sun, 05 Feb 2012 00:00:00 GMT Hi Judi, I am happy to hear from you but very sorry that you are still feeling Annie's loss so deeply.  It took me years to get over our previous dogs demise.  I don't think you EVER get over it, just move it a little farther back in your mind, only to bring it out when we are having a quite moment....alone.  I still cry for Muffin.  I also don't believe in trying to replace a former pet....Mufffin was Muffin and received Muffin love.... Chica is a completely different personality, all in her own right and receives love all of her own. I am glad someone used the word "envious".  I felt very badly about myself all these years.  I was envious of all of the other pet parents that got to spend 11, 12, 13, 14 and more years with their pups before the TCC arrived on their scene.  Chica was only 6 when she was DXed.  I used to say to my hubby, "What kind of person am I? That I envy someone's good fortune.  I have never been like this in my whole life!" NOW I can see it for what it is.....it's NOT envy OF someone....it's a deep yearning for what we have lost and what we know we will lose, sprinkle that with fear and uncertainty and....yes....it seems like envy.  Perfectly understandable, when you consider what we all have gone through.  I came to this understanding by reading (carefully) your litany of things we all go through, have gone through and will go through again and again. With this said, I am deeply sorry for your loss of Annie. We are happy to accept your positive energy....we will make good use of it.  I know you have prayed for all of us on this site, just as I have prayed for all of you.  Our day is coming, I am constantly looking over my shoulder, wondering...not if, but when, I dread it with all my heart.  Keep in touch. ChicasMom, Lynn ChicasMom Fri, 03 Feb 2012 00:00:00 GMT If you're not that far from Philadelphia, I would recommend UPenn Veterinary Hospital.  They are the best.  I have been taking my Bailey to see Dr. Clarke now for almost a year.  They really care about their patients and are very interested in trying to find better ways of dealing with this disease. Baileysmom97 Fri, 03 Feb 2012 00:00:00 GMT also does anyone know of any vets that specialize in TCC in the New York area? bailey661 Thu, 02 Feb 2012 00:00:00 GMT I am so sorry for all of you dealing with this heartache and sorrow, my heart goes out to you all. It is truly one of the saddest things I have ever had to go through myself. My beagle/jack russel Bailey was diagnosed with a few UTIs over the past year and then about 3 weeks ago we found a Tumor in her urethra thats extending into her bladder as well. WE immediately started her on peroxicam, pepcid, and a flax seed oil/cottage cheese mixture.She was having alot of difficulty urinating frequently, and straining when she would urinate, and her urine appeared to be blocked so it dripped out. Since the peroxicam and flax seed combo she has made very good progress. Going out much less often and her pee is now flowing instead of dripping out. I dont know if any of you have tried the flax seed oil/cottage cheese (budwigs cancer diet), but it is worth a try. bailey661 Thu, 02 Feb 2012 00:00:00 GMT I'm so sorry that you lost Annie on this day a year ago.  Anniversaries can be so painful.  I am lucky enough to still have my dachshund Rocky, but know that our time together is limited.  Rocky was diagnosed in August, and now the vet says we'll have "at least another six months."  I am treasuring each day with him.  I can't even imagine how you must be feeling right now, and I know that I will have to face that enormous loss too in time.  I remember reading your posts when I first found this community, and I remember how much love you had and have for Annie. I hope some day you do decide to get another  dog to share your life with because that dog would be lucky indeed, and Annie would want you to be happy. Nita Thu, 02 Feb 2012 00:00:00 GMT I'm so sorry that you lost Annie on this day a year ago.  Anniversaries can be so painful.  I am lucky enough to still have my dachshund Rocky, but know that our time together is limited.  Rocky was diagnosed in August, and now the vet says we'll have "at least another six months."  I am treasuring each day with him.  I can't even imagine how you must be feeling right now, and I know that I will have to face that enormous loss too in time.  I remember reading your posts when I first found this community, and I remember how much love you had and have for Annie. I hope some day you do decide to get another  dog to share your life with because that dog would be lucky indeed, and Annie would want you to be happy. Nita Thu, 02 Feb 2012 00:00:00 GMT thanks, I will check it out, my husband will be thrilled if they look like she'd let us go near her with them,, I guess the tumor presses on the colon, so the rear area is tender,, we were hoping to have her wear them at night atleast.. so hard. I have twins, and the main floor is basically not an option, we play upstairs or in the basement..   sadiemagoo Thu, 02 Feb 2012 00:00:00 GMT Stephanie, Peekeepers are nothing like diapers....much better.  You use a Poise or Tena incontinence pad in them and away you go. They fit up to 35 lbs. Go to PeeKeeper.com . I have no stake in the mfg of them.  Some nice ladies in PA make them and are lifesavers. They are really very good and I always pass the info along. Tinkle Trousers are another creation to take the place of diapers (Ugh..to diapers). Some pet parents on this site have used them also and were very happy with them. ChicasMom, Lynn ChicasMom Thu, 02 Feb 2012 00:00:00 GMT On Feb 02, 2012 5:12 PM anniebananie wrote: Today is the one year anniversary of the day Annie lost her fight with TCC.  I still check out the forum from time to time.  Annie lived for 16 mos. past dx.  When I read on the forum, dogs are surviving 2 to 3 yrs (like little Chica), I am happy for their owners but oh so envious.  What I would give to have another year with her, God, just even one more month.  Because of heart issues and her age (14) we didn't do chemo, just meticam, baytril and holistic diet.  She did wonderful until the last month.  She never peed blood but we had to get up every 2 hours to let her out.  She would not wear diapers.  Her kidneys were shutting down and her tumor had grown. She was so exhausted from no sleep and she had lost quality of life. You are all going through what we did-no sleep, no social life (as we couldn't leave her alone), lots and lots of extra laundry and shampooing carpets, frustration and worry when they don't eat, the expenses (thousands of dollars).  But cherish each and every moment you spent with your dog because when they are gone, it is so painful and there is this unmeasurable void in your life.  Piccolo's mom wrote that it feels like her heart is collapsing on itself like a vaccum.  I haven't gotten another pet yet but hopefully will. She made me laugh everyday and will be a hard act to follow. I am so thankful I had her in my life for 14 years.  I miss her so much. Love and prayers to all of you and your furbabies.  Like Maureen, I send positive energy to all of you. Thank you Maureen for your kind words to all of us that are grieving the loss of our beloved companions.  It meant a lot to me. Judi (Annie's mom) Winnipeg, Canada Oh Judi, this breaks my heart.  Our battle started on the same day that yours ened.  You took wonderful care of her.....no doubt that's why she was with you so long.  They have a strong will and a strong love for us and I think that keeps them here too, don't you?  You certainly were blessed to have her with do and doing so well until that last month.  I send you gentle hugs and wonderful memories of Annie today. Heidi and Chloe   MomtoChloe Thu, 02 Feb 2012 00:00:00 GMT She has,,, and I am blessed, but it makes me hestitate if I'd ever have another beagle and I love the breed.  Finding out after the fact they are one of the top 5 that get bladder cancer... How is Mugsy so far?  I have a good friend I met who breeds beagle pups, if I ever get another it will be from her,, check out melodybeagles when you have a chance,, so adorable.  Thank you for your kind words,, I just wanted to find someone who has gone through this.. I spent most of yesterday talking to the oncologist, my vet who I LOVE!, the assistant of avet in Purdue that specializes in the research of TCC, holistic vet,, and my family... we had taken Sadie for a long walk, and afterwards she just couldn't get comfortable,, the tumor irritated.. I've now realized eventhough she wants to go, the walks need to be abreviated, or long car rides which she also loves... I don't think her time with me is done yet, I hope not,,, I"ve been blessed to be home this last two years because I had twins and I am a teacher, I think that has helped her stay with me this long... and hopefully a little longer.  Her tumor is taking up 80-90% of her bladder and growing in the eurethra,, did you have a lot of blood? straining issues? Hate to bring up a subject that causes you pain, it's just this website has been helpful to talk to others going through this, since noone around here seems to talk about it. or know how to help emotionally with this journey.. I appreciate any insight you can share,, I want quality of life for her... I won't make her suffer unnecessarily ... thanks for listening..  sadiemagoo Thu, 02 Feb 2012 00:00:00 GMT are pee keepers, diapers,, we bought them for dogs, and she was having nothing to do with them.. Check about Rimadyl,, not as many side effects as Piroxicam, we have had success with only rimadyl, and the antibiotic, now a small dose of tramadol for comfort...   sadiemagoo Thu, 02 Feb 2012 00:00:00 GMT Today is the one year anniversary of the day Annie lost her fight with TCC.  I still check out the forum from time to time.  Annie lived for 16 mos. past dx.  When I read on the forum, dogs are surviving 2 to 3 yrs (like little Chica), I am happy for their owners but oh so envious.  What I would give to have another year with her, God, just even one more month.  Because of heart issues and her age (14) we didn't do chemo, just meticam, baytril and holistic diet.  She did wonderful until the last month.  She never peed blood but we had to get up every 2 hours to let her out.  She would not wear diapers.  Her kidneys were shutting down and her tumor had grown. She was so exhausted from no sleep and she had lost quality of life. You are all going through what we did-no sleep, no social life (as we couldn't leave her alone), lots and lots of extra laundry and shampooing carpets, frustration and worry when they don't eat, the expenses (thousands of dollars).  But cherish each and every moment you spent with your dog because when they are gone, it is so painful and there is this unmeasurable void in your life.  Piccolo's mom wrote that it feels like her heart is collapsing on itself like a vaccum.  I haven't gotten another pet yet but hopefully will. She made me laugh everyday and will be a hard act to follow. I am so thankful I had her in my life for 14 years.  I miss her so much. Love and prayers to all of you and your furbabies.  Like Maureen, I send positive energy to all of you. Thank you Maureen for your kind words to all of us that are grieving the loss of our beloved companions.  It meant a lot to me. Judi (Annie's mom) Winnipeg, Canada  anniebananie Thu, 02 Feb 2012 00:00:00 GMT On Feb 02, 2012 2:38 PM sadiemagoo wrote: My Sadie, is up to 2 years 1 month,, although we know the tumor is now taking about the majority of her bladder.  We never did chemo, just rimadyl and antibiotics and a mitaki oil which is basically mushroom oil packed with Vitamin D.. days that are hard are very hard, but she isn't quite ready to leave us yet.  I believe I will know when it is time,, for now I thank god that she is still doing okay,, other than the countless accidents, which by  the way, we use Anti Icky Poo, highly recommend, and if blood on the carpet, I spray Peroxide on it also, it removes that rusty look.. anyways, Congrats on your one year anniversary, I truly understand the journey you have been on. StephanieThank you Stephanie,  wow 2 years and 1 month....Awesome.  We have not done chemo either; right now only Piroxicam, Cipro, Pepcid and just lately Sucralfate.  Chloe's tumor is in the worst place it could be; in the neck of the bladder and partially into the eurethra.  But, she is still urintating pretty well overall.  Do they make Pee Keepers to fit Sadie?  They have saved my carpets when I am at work and Chloe can't hold it. Hugs, Heidi   MomtoChloe Thu, 02 Feb 2012 00:00:00 GMT Stephanie-  So happy to hear your baby beagle has survived this long. I lost my baby beagle, Copper, last March seven months after his diagnosis.  I still miss him everyday and sometimes even cry still.  Please know that I am praying for all of you who are going through this grieving process of letting go of your beloved companions. It's so difficult.  Keep doing what you are doing and above all keep loving, kissing, petting, cooing to, your babies.  Copper was never a love puppy, but when he was sick, he sure ate up all the love. Mugsy (my new beagle from rescue) and I send our positive energy to all of you.  Copper's Mom (and now Mugsy's, too)  Maureen, Illinois  CoppersMom Thu, 02 Feb 2012 00:00:00 GMT My Sadie, is up to 2 years 1 month,, although we know the tumor is now taking about the majority of her bladder.  We never did chemo, just rimadyl and antibiotics and a mitaki oil which is basically mushroom oil packed with Vitamin D.. days that are hard are very hard, but she isn't quite ready to leave us yet.  I believe I will know when it is time,, for now I thank god that she is still doing okay,, other than the countless accidents, which by  the way, we use Anti Icky Poo, highly recommend, and if blood on the carpet, I spray Peroxide on it also, it removes that rusty look.. anyways, Congrats on your one year anniversary, I truly understand the journey you have been on. Stephanie sadiemagoo Thu, 02 Feb 2012 00:00:00 GMT Heidi and Chloe (MomtoChloe) we live in Staunton, Virginia   MomtoChloe Thu, 02 Feb 2012 00:00:00 GMT Good Morning All, Today marks one year ago that we got the horrible diagnosis of TCC for our baby girl, Chloe.  We were told she would have only 5 to 6 months.  Well, she proved them all wrong.  We have been through some rough times.  I have been by her side all the way and will always be there.  The lack of sleep from going outside and walking the street to pee, the difficuilty staying awake at work, the UTI's, the feeling of helplessness, the anger, the constant prayers.....I have been through all of this just like you all and my heart is with each of you as you go through it too.  But I know you all agree with me that it is all worth it.  Things will never be the way they were before this, but Chloe has taught me so much on this journey....and she will continue to teach me.  Only God knows how much more time we have, but He holds me up every day and keeps me strong.  Each one of us here was chosen to walk this path; why, I wish I knew.  But we will know one day.  Like many of you, there have been times when I thought Chloe would be leaving me, only to have her bounce back.  Our babies are real fighters for sure. Please give your babies a special kiss for me today! Hugs to all, Heidi and Chloe   MomtoChloe Thu, 02 Feb 2012 00:00:00 GMT Barbara and Hubby.....I will be praying for you too and your sweet Molly! Hugs, Heidi and Chloe   MomtoChloe Thu, 02 Feb 2012 00:00:00 GMT Barbara, Barry and I are praying for you and Molly. Christine PiccoloMom Thu, 02 Feb 2012 00:00:00 GMT Christine and Piccolo (and Barry and Mallowmar) live in beautiful Athens, Ga! Swing by! You know I am a dog friendly establishment! Lol! Feels good to laugh! PiccoloMom Thu, 02 Feb 2012 00:00:00 GMT Barbara, You are in my thoughts and prayers during this difficult time. Love, Nita Nita Wed, 01 Feb 2012 00:00:00 GMT Barbara, I am so sorry.  I will pray for you and pray that God will give you a clear and direct answer to this decision you have to make.  The fact the we have the power to end the life of someone we love is hard to accept.  Therefore, I have, many times, asked God to make that decision for me so there is no mistaking when the time comes.  Praying for you, Debbie, Peaches mom MyPeaches Wed, 01 Feb 2012 00:00:00 GMT On Feb 01, 2012 8:50 PM barbef wrote: On Feb 01, 2012 1:42 PM ChicasMom wrote: Chica and Lynn - NORTH CAROLINA By way of...NJ, MD and VA.Thank you for quoting me about the support group.  I am actually in NY (Westchester County) and I have the advantage of some of the best doctors and hospitals out there.  Unfortunately with this miserable disease the end is always the same. I guess my angry side is coming out now...since I've cried so much I feel (even though I know I'll cry more) I've exhausted the sadness side.  We're actually on our way to the vets office today because Molly still hasn't eaten and is now just laying around.  She picks her head up to drink water but seems very out of it.  They are going to do a blood test to tell us where the kidney levels are and then we are asked to decide. "Decide"; what a strange word. Decide to end the most precious addition to your family's life. They ask us to decide. My friends who have gone through this before have said it's for the sake of the dog who is probably suffering so I guess  the decision to be at peace vs. suffering is an easy choice.  It's just so hard and one that I can't believe I'm so close to having to make. All my love as always to your furry loves and you. Barbara, Molly's MommyBarbara-- Ask your vet about nausea.  The first time Bailey went on the antibiotics, she was the same way.  She would show no interest in eating and her energy level was down.  I used think that if she wasn't feeling well, what was the point of all of this?  The anti-nausea meds do help Bailey but I can still tell there is a difference in her spunk once she's off the antibiotics.  Hoping for the best for Molly.  Hang in there. Karin Baileysmom97 Wed, 01 Feb 2012 00:00:00 GMT Barbara, Hubby and Molly....I am praying for all of you. I'm not often speechless, but right now I am so upset that I cannot form a thought or words. Please let us know. ChicasMom, Lynn ChicasMom Wed, 01 Feb 2012 00:00:00 GMT Thanks Karen for the advice.  I do have pee pads all over by the door.  Sometimes she goes on them and sometimes she doesn't.  I don't even care that I will have to replace my carpet, but I just don't want her to try to hold it, which she does.  She will hold it as long as she can, and if I don't get to her in time, she will pee whereever she is at the moment.  I don't mind at all, but I just don't want it to become an issue with my husband.  I try to clean up the messes before he see them.  He is not as compassionate as I am.  Peaches sleeps with me and has never been crated, so that won't work.  I also bought a 6' x 6' piece of outdoor carpet and put a shower curtain liner underneath it and put it by the door and tried to encourage her to pee on it.  Sometimes she does and sometimes she doesn't.  UGH.  Anyway, I'm taking one day at a time looking forward to warmer weather when I can leave the door cracked open. Debbie (Peaches) - Pennsylvania MyPeaches Wed, 01 Feb 2012 00:00:00 GMT We are all praying for you.  God bless. Iloverio Wed, 01 Feb 2012 00:00:00 GMT On Feb 01, 2012 1:42 PM ChicasMom wrote: Chica and Lynn - NORTH CAROLINA By way of...NJ, MD and VA.Thank you for quoting me about the support group.  I am actually in NY (Westchester County) and I have the advantage of some of the best doctors and hospitals out there.  Unfortunately with this miserable disease the end is always the same. I guess my angry side is coming out now...since I've cried so much I feel (even though I know I'll cry more) I've exhausted the sadness side.  We're actually on our way to the vets office today because Molly still hasn't eaten and is now just laying around.  She picks her head up to drink water but seems very out of it.  They are going to do a blood test to tell us where the kidney levels are and then we are asked to decide. "Decide"; what a strange word. Decide to end the most precious addition to your family's life. They ask us to decide. My friends who have gone through this before have said it's for the sake of the dog who is probably suffering so I guess  the decision to be at peace vs. suffering is an easy choice.  It's just so hard and one that I can't believe I'm so close to having to make. All my love as always to your furry loves and you. Barbara, Molly's Mommy barbef Wed, 01 Feb 2012 00:00:00 GMT Chloe's mom, Tennessee Chloebeaglemom Wed, 01 Feb 2012 00:00:00 GMT Hi from Nita and Rocky, our standard dachshund. We live in Michigan Nita Wed, 01 Feb 2012 00:00:00 GMT Bailey & Karin (Baileysmom97), New Jersey Baileysmom97 Wed, 01 Feb 2012 00:00:00 GMT Marianne (Rio) -- Colorado Iloverio Wed, 01 Feb 2012 00:00:00 GMT On Jan 30, 2012 4:41 PM MyPeaches wrote: Hi Christine, I am so with you.  I have been told by 2 people "why don't you just put her down?".  My response is, after much crying, "how dare you say that?".  These 2 people have no idea.  Peaches is completely "normal" except for the peeing issue.  She still LOVES everything she loved for years.  She just has to pee alot.  Her pee has been mostly bloody for the past couple of months which has me on a rollercoaster too.  Her culture says she does not have an infection, and this is just the new "normal".  And just over the past couple of days, she has had me up 3 times in the night to go out to pee.  It used to be just once a night.  I am so tired right now, my eyes just ache, and I can't think straight.... and I am at work trying to function.  But I'll keep doing this as long as I have to.  I refuse to end her life becasue this is not convenient to me.  I just ordered the Tinkle Trousers (a larger version of the Pee Keeper), but haven't had the courage to put them on her yet.  But I guess I will have to if I ever want to sleep.  I, too, just wish I knew what was next.  This is just so painful to watch. DebbieHi Peaches mom/Debbie, Awhile back I read on here two ideas that I thought were brilliant and put in my file to use in the future when my Emily gets to needing pee every two hours. First, one is getting the pee pads, like you might use with puppies for training, and place them right at the doors so that when Peaches needs to go out to pee, she can use the mats at the door. Another person said tht she bought one of the large wire crates and an elevated doggie hammock bed. She put both of these in her bedroom-the bed inside of the crate-and also added one of the fake grass potty spots in the crate. That way her pup could sleep on the elevated bed up away from the pee spot, but get up and go to the pee spot to potty and go back to a dry bed. If I remember, her pup was already crate trained, sothis worked well. Emily LOVES her crate, so this sounds like the perfect set up for us in the future. I didn't know if you had read or tried these tricks yet! I thought it might help you to get some sleep so that you can stay healthy and helping Peaches! Karen, Emily's (and Murphy) mom LittleKaren Wed, 01 Feb 2012 00:00:00 GMT sadies mom, Ohio sadiemagoo Wed, 01 Feb 2012 00:00:00 GMT Chica and Lynn - NORTH CAROLINA By way of...NJ, MD and VA. ChicasMom Wed, 01 Feb 2012 00:00:00 GMT Christine, HERO.....me?.....naw.  Our little creatures are the hero's in all of this.  We.....are just mere caretakers of these hero's. I am sure we caretakers have a special place in God's heart for taking special care of His little creations. He...has not caused this malady to befall them.  It is the work of human hands and human carelessness (herbacides, pesticides, etc.). Allow me to digress for a moment here. Let's take a mommy time out and respond to this sentence of posting: "There are so many wonderful Mommy's on this site. I wish we could start a support group for each other but I'm sure we're all miles away." (Barbara, Molly's Mom) Respond with the "STATE" that you live in.  We ARE a support group and knowing where your support is coming from will give us a light moment (a welcomed respite from the day to day pounding of this disease).  The moderator probably will not mind...this is not personal information that anyone can use.  Only us...to cement our support group. I hope no one thinks this a "childish" request.  I often think about you and your little furbabies, and where you are at....I'm sure some of you do too. Keep the faith....spring is coming....our little creatures can go outside in the sun and sniff the air for all the great spring smells. Ahhh...I can't wait! ChicasMom, Lynn ChicasMom Wed, 01 Feb 2012 00:00:00 GMT I have gone through all that with my sweet Sadie.. alot of times, the blood meant another bladder infection.  It would help with an antibiotic to lessen the amount, but its never really disappeared. I was also told the stuff we sometimes see in the urine, is part of the tumor that has broken off. They are considered "hot" so they easily bleed.  I spoke to Purdue University. The doctor there is the leading doctor for this type of cancer.  I never met her but she has a very understanding, sympathetic, and helpful secretary that has shared a lot of information, which I craved because I was so  frustrated trying to find a way to help.  sadiemagoo Wed, 01 Feb 2012 00:00:00 GMT On Jan 11, 2012 12:55 AM gabriella68 wrote: Dear Christine Great to see the picture of little Piccolo, she looks so cute and perky! It's great she's been doing well so far and I hope there're many more months to come when you guys can enjoy life together. My doggy was diagnozed with the cancer when I noticed that even though she was taking her antibiotics for a bladder infection, she was leaving tiny drops of blood behind her on the bed. So blood was present for her during the whole time from diagnosis to her passing away (7 months later). Towards the end, she did seem to pass more bloody urine but then often this got better and we were back to 'normal' amounts. Unfortunately, her end came when the tumor started to bleed uncontrollably and there was no way of stopping the loss of blood. But by this time she wasn't interested in eating/drinking either, so the fact that Piccolo is still eating is, I think, a very good sign. The vets could say it for sure, but I think each dogs goes through a different process with this disease (e.g. my doggy was never bothered by the piroxicam she had to take and the chemo didn't affect her either, while others suffer a lot more), so although it's good to be clued up about the possible signs of any worsening of Piccolo's condition, I'd say try to keep calm because it may just be another trick of that darn tumor and Piccolo will be going on for much longer. From my experince, some dogs whine when in pain, others become listless or withdrawn, lose their appetite and don't want you to touch them even though they may have loved it before. Perhaps others can add to this list; again, my doggy didn't seem to be in pain (the the vet didn't think she was in pain either-and I so hope that we were right!) so it's possible to go to the very end with relatively 'little' discomfort. I hope this helps and I wish both of you strength for handling this disease. Kind regards Gabriella Hi Gabriella, I am new to this but read your post.  My beagle Sadie was diagnosed 2 years ago.  We have treated all along with rimadyl, antibiotics, and now added tramadol to the mix.  Lately the straining has gotten worse, with peeing on furniture, in addition to the carpeting.  We will be replacing it.  I just wish I knew the progression of this disease.    We went on a beautiful walk today because it was almost 60 here in Ohio, and she did great. But tonight she has been so uncomfortable, I'm assuming from the pressure of the tumor, that is taking up 80-90% of her bladder and is growing in her eurethra.  If you could shed some light on th is... again this post drew me, it's almost 3 am, I have twins who were up, Sadie who is like a third baby, and I'm worried about them all... I won't let her suffer as hard as that decision is.. Stephanie sadiemagoo Wed, 01 Feb 2012 00:00:00 GMT On Jan 31, 2012 6:49 PM Baileysmom97 wrote: My dog Bailey has gone through this a few times.  She is on her 4th infection in less than a year.  Her doctor prescribed her an anti-nausea.  The one Bailey takes is Odansetron and she gets one with a small meal during the day and then one with her meal at night.  I usually stick it in a piece of meatball.  Hopefully Molly will start eating again.  Also, I have added probiotic supplements to her food and it seems to help...no more stomach upset.  Just watch where you obtain the anti-nausea.  The first batch I got from Walgreens and it cost me $5 per tablet!  I now get them straight from UPenn and it's only $1 per tablet. Oh my goodness, Baily's Mom! Nausea has not occurred to me when Piccolo's had her "down time". Picture me doing the "smack- right hand palm side up- on the forehead! We were so focused on torbugesic for pain at those times that nausea did not cross my mind. I'm always learning, thanks to you all! Thank you- I have another tool for the "toolbox". Nose-kiss to Baily'! PiccoloMom Wed, 01 Feb 2012 00:00:00 GMT On Jan 31, 2012 6:49 PM Baileysmom97 wrote: My dog Bailey has gone through this a few times.  She is on her 4th infection in less than a year.  Her doctor prescribed her an anti-nausea.  The one Bailey takes is Odansetron and she gets one with a small meal during the day and then one with her meal at night.  I usually stick it in a piece of meatball.  Hopefully Molly will start eating again.  Also, I have added probiotic supplements to her food and it seems to help...no more stomach upset.  Just watch where you obtain the anti-nausea.  The first batch I got from Walgreens and it cost me $5 per tablet!  I now get them straight from UPenn and it's only $1 per tablet. Hi Bailey's Mom, Thank you for the info on the anti-nausea meds.  I will check that out tomorrow.  I now have a plastic try with flowers on it to keep all of Molly's medicine..it now includes a syringe. I didn't think I would have to use it because she was eating and taking her meds so well.  This disease really has its up and downs. I want to thank you and Chica's mom and Piccolo's mom who I've gotten so much inspiration and encouragement from. We are all really great "mommies".  Please all keep in touch. This site means so much to us all. Love and Prayers, Molly's mom, Barbara barbef Wed, 01 Feb 2012 00:00:00 GMT On Jan 31, 2012 7:37 PM ChicasMom wrote: Hi Barbara, Thank goodness she is still drinking! Just keep offering Molly things that you have cooked. Chicken, salmon and ground beef are all good (not combined). Mash it up real good with some water (I use a small food proccessor). If she starts eating that, start adding some kibble or whatever she eats daily. Try not to fret, usually when our pets don't feel well they will go off their "feed". If she stops drinking it's usually an emergency. All you can do is keep on offering. In a few days when she starts eating again you're going to say to yourself "and WHY was I so worried about her not eating?" This, not eating, happens more often than we would like it to....lots of variables with TCC that makes them feel unwell. Drives us all crazy! Keep your chin up, be positive....keep offering food. I am positive you will find some delicacy that Molly will go for. Scared, crying and desperate is all natural. This disease stinks. Flip it "a bird" and trudge forward........ ChicasMom, LynnDear Lynn, Thank you for you kind advice and encouragement.  There are so many wonderful Mommy's on this site. I wish we could start a support group for each other but I'm sure we're all miles away. I will continue to offer Molly food...I've already cooked 5 different things today alone.  I did get her to eat some Boar's Head roast beef at lunch and then went out and bought a pound of it for dinner and she wouldn't touch it. I hope Chica is doing well.  At least I take comfort in knowing that I have been the best mommy I could be for my little girl and I know all of us out there love our babies with all our might. Take care of your girl and thank you again.   Barbara, Molly's mommy barbef Wed, 01 Feb 2012 00:00:00 GMT Hi Barbara, My heart is with you tonight. I completely know what you mean about the "test kitchen"- we've tried roast beef (AND like you, Boarshead), salmon, steak, chicken, scrambled eggs (this actually worked once), bacon, bad carbs (pancakes/syrup/cookies/cupcakes), cheese.... All made with love. I know how it feels when our babies still won't eat after all of that (an irrational sense of failure). I KNOW where you are. I also want to share: Sometimes I cry so hard that I truly feel like my heart is collapsing on itself like a vaccum. Sometimes I wake up at night and "remember" how sick Piccolo is and the tears just slide out sideways and soak the pillow. Sometimes I dont want to eat because my baby wont eat. Like you, I'll have days when I come home and just cry (hiding it all from little Picky-poo....Daddy takes over, then). And after all that, I still have to get in the car and drive to work and function (all the while feeling just numb and in a haze). I have mastered the art of sitting in meetings listening to the "blah blah blah", all the while thinking how superfluous it all is in comparison to the the fact my cherished companion is close to leaving me. I know I'm not alone in this! And then some days I'm strong- so strong I just give the cancer my duclaw! Just like Chica's mom (our hero!). Fight fight fight (cry) fight! It never ceases to amaze me how these little creatures can completely hold our hearts. Sounds like you are going through the new normal for emotions. Knowing that doesn't make it all better, but I hope it helps. Barry and I felt alone before we found this forum. The support here is amazing. The only thing that would make it better is if we could give each other real hugs instead of the virtual ones. Please, come back tomorrow and let us know how Molly is doing. We're all reading and thinking of food ideas! And please give Molly a kiss from us! Christine PiccoloMom Wed, 01 Feb 2012 00:00:00 GMT On Jan 31, 2012 8:08 PM PiccoloMom wrote: Hi Barbara, We had the same thing happen to Piccolo a few months back- it is one of the reasons why she is permanently on Baytril.  It is such a gut-wrenching feeling when our babies don't eat.  When I went through it with Piccolo, I called my Mom and told her I finally understood why she would get so upset when I'd refuse to eat when I was sick as a child.  It is a very good, good, sign that Molly is drinking water.  That is the first thing my vet asked me when Piccolo was refusing food- so please take some comfort in that.  It was a very smart idea you had about grinding the Baytril up and administering with a syringe.  If she is accepting the syring, you may want to mix in a little chicken broth and give that to sweet Molly.  Even just a few mililiters will help.  It may feel like "forced feeding", but tough love isn't always sugar coated.  And like Lynn wrote, keep offering food to her- all different types.  You never know what they'll respond to.  Piccolo, who I had on my lap constantly, finally lifted her chin up when my husband handed me my dinner in a bowl: a new recipe for curried lentils! Crazy! Hang in there.  I know it is really tough.  I can't tell you how many times I've thought, "Oh no. This is it. This is really it", only to find my girl bounces back.  Its as if she just needed to go into hybernation mode to send all of her healing energy towards fighting.  Send Molly all the positive energy you have--I truly believe our love helps them fight. <<hugs>> ChristineDear Christine, Thank you so much for your kind words and encouragement.  I feel like we're at the end of the road and I haven't stopped crying since I came home from work.  I will try the chicken broth in the syringe..it's amazing how many good ideas you have.  I'm just sorry they revolve around this awful subject. I just sent my husband out for boar's head roast beef. I've been cooking and buying all kinds of things. My kitchen looks like a test kitchen...but I'll keep doing as long as I can for my precious angel. Once again, I truly appreciate your prompt response..I've come to rely on this site a lot. Much love to you and your precious Piccolo. Barbara, Molly's Mom barbef Wed, 01 Feb 2012 00:00:00 GMT Hi Barbara, We had the same thing happen to Piccolo a few months back- it is one of the reasons why she is permanently on Baytril.  It is such a gut-wrenching feeling when our babies don't eat.  When I went through it with Piccolo, I called my Mom and told her I finally understood why she would get so upset when I'd refuse to eat when I was sick as a child.  It is a very good, good, sign that Molly is drinking water.  That is the first thing my vet asked me when Piccolo was refusing food- so please take some comfort in that.  It was a very smart idea you had about grinding the Baytril up and administering with a syringe.  If she is accepting the syring, you may want to mix in a little chicken broth and give that to sweet Molly.  Even just a few mililiters will help.  It may feel like "forced feeding", but tough love isn't always sugar coated.  And like Lynn wrote, keep offering food to her- all different types.  You never know what they'll respond to.  Piccolo, who I had on my lap constantly, finally lifted her chin up when my husband handed me my dinner in a bowl: a new recipe for curried lentils! Crazy! Hang in there.  I know it is really tough.  I can't tell you how many times I've thought, "Oh no. This is it. This is really it", only to find my girl bounces back.  Its as if she just needed to go into hybernation mode to send all of her healing energy towards fighting.  Send Molly all the positive energy you have--I truly believe our love helps them fight. <<hugs>> Christine PiccoloMom Tue, 31 Jan 2012 00:00:00 GMT Hi Barbara, Thank goodness she is still drinking! Just keep offering Molly things that you have cooked. Chicken, salmon and ground beef are all good (not combined). Mash it up real good with some water (I use a small food proccessor). If she starts eating that, start adding some kibble or whatever she eats daily. Try not to fret, usually when our pets don't feel well they will go off their "feed". If she stops drinking it's usually an emergency. All you can do is keep on offering. In a few days when she starts eating again you're going to say to yourself "and WHY was I so worried about her not eating?" This, not eating, happens more often than we would like it to....lots of variables with TCC that makes them feel unwell. Drives us all crazy! Keep your chin up, be positive....keep offering food. I am positive you will find some delicacy that Molly will go for. Scared, crying and desperate is all natural. This disease stinks. Flip it "a bird" and trudge forward........ ChicasMom, Lynn ChicasMom Tue, 31 Jan 2012 00:00:00 GMT My dog Bailey has gone through this a few times.  She is on her 4th infection in less than a year.  Her doctor prescribed her an anti-nausea.  The one Bailey takes is Odansetron and she gets one with a small meal during the day and then one with her meal at night.  I usually stick it in a piece of meatball.  Hopefully Molly will start eating again.  Also, I have added probiotic supplements to her food and it seems to help...no more stomach upset.  Just watch where you obtain the anti-nausea.  The first batch I got from Walgreens and it cost me $5 per tablet!  I now get them straight from UPenn and it's only $1 per tablet.  Baileysmom97 Tue, 31 Jan 2012 00:00:00 GMT Barbara, I am so sorry.  I know that feeling of panic when your dog will not eat.  I have found Rio may lose his appetite for a few days, but then it comes back, just like I might lose my appetite when I don't feel well.  I resorted to cooking fresh salmon and steak, which he did eat eventually.  (Of course, one of my friends remarked that "You are talking about a DOG, right???)  But nevertheless we do what we have to do.  Chicken and brown rice are also good and soothing on the stomach, if Molly will eat them.  Hopefully, this too will pass.  But I know how difficult it is to get through at the time. Iloverio Tue, 31 Jan 2012 00:00:00 GMT On Jan 30, 2012 6:19 PM PiccoloMom wrote: Thank You so much for your support everyone!  It means so much to us.  It does get overwhelming at times- some days are better than others and vice versa.  Washing bedding and changing diapers IS the new normal--I've found we're all pretty adaptable in our home.  Piccolo is Like Peaches- completely normal except for the peeing issue.  I like Chloe's mom's statement about our parents changing our diapers- this is no different in my book.  Heidi- I loved reading about Chloe standing still for her diaper.  Piccolo already knows to lower her head a bit when she sees me approach with the PeeKeeper (it slips on over her head).  And she knows that Daddy is much slower at adjusting/re-adjusting the velcro tabs (she hates the sound of velcro), so she'll walk over to me if he is holding the diaper.  These creatures are such huge personalities! Yesterday Piccolo was running around and rolling over on the rug with her sister.  Then she'd do the run and dodge routine with us- then back to barking and wagging her tail.  When I see this, I KNOW I'm right to trust my gut.  There is so much life in her!  Moments like this make it all worth it.  The getting up at night, constant washing of bedding, rotating diapers, and the frantic run to get the diaper on before an accident happens......yes, it is tiring but it is sooooo worth it.  Like Chica's mom said, I will have plenty of time to rest later. Right now I know I'm doing everything I can to make my baby comfortable.  Now, if I could get her to learn to love having me in her face giving kisses all the time (independedn Doxie). :-)Hello to everyone out there going through this horrible nightmare.  I've been on here only a few times and have gotten lots of information.  At this time, I'm looking for any feedback I can get.  My Molly who has TCC has been very stable up until yesterday.  She is on peroxicam and an antacid but developed a UTI.  I noticed she was groaning while urinating and rushed to the vet..they have put her on Baytril and all of sudden (basically overnight) has stopped eating and thus I cannot give her the drug.  My pharmacist quickly make a liquid out of the pills and we have to administer the solution through a syringe.  She's only had 1 1/2 doses since it just happened yesterday.  Does anyone have any advice on how to get her to eat.  I have made a variety of things to no avail. I keep trying but I am so fearful now that she's not eating.  Has anyone had an experience with a UTI and not eating.  She is still drinking her water, but turns her nose away at everything I offer.  Any help, advice, etc. would be so appreciated.  I'm scared, crying and desperate for advice.   Molly's Mom, Barbara barbef Tue, 31 Jan 2012 00:00:00 GMT Thank You so much for your support everyone!  It means so much to us.  It does get overwhelming at times- some days are better than others and vice versa.  Washing bedding and changing diapers IS the new normal--I've found we're all pretty adaptable in our home.  Piccolo is Like Peaches- completely normal except for the peeing issue.  I like Chloe's mom's statement about our parents changing our diapers- this is no different in my book.  Heidi- I loved reading about Chloe standing still for her diaper.  Piccolo already knows to lower her head a bit when she sees me approach with the PeeKeeper (it slips on over her head).  And she knows that Daddy is much slower at adjusting/re-adjusting the velcro tabs (she hates the sound of velcro), so she'll walk over to me if he is holding the diaper.  These creatures are such huge personalities! Yesterday Piccolo was running around and rolling over on the rug with her sister.  Then she'd do the run and dodge routine with us- then back to barking and wagging her tail.  When I see this, I KNOW I'm right to trust my gut.  There is so much life in her!  Moments like this make it all worth it.  The getting up at night, constant washing of bedding, rotating diapers, and the frantic run to get the diaper on before an accident happens......yes, it is tiring but it is sooooo worth it.  Like Chica's mom said, I will have plenty of time to rest later. Right now I know I'm doing everything I can to make my baby comfortable.  Now, if I could get her to learn to love having me in her face giving kisses all the time (independedn Doxie). :-) PiccoloMom Mon, 30 Jan 2012 00:00:00 GMT Hi Christine, I am so with you.  I have been told by 2 people "why don't you just put her down?".  My response is, after much crying, "how dare you say that?".  These 2 people have no idea.  Peaches is completely "normal" except for the peeing issue.  She still LOVES everything she loved for years.  She just has to pee alot.  Her pee has been mostly bloody for the past couple of months which has me on a rollercoaster too.  Her culture says she does not have an infection, and this is just the new "normal".  And just over the past couple of days, she has had me up 3 times in the night to go out to pee.  It used to be just once a night.  I am so tired right now, my eyes just ache, and I can't think straight.... and I am at work trying to function.  But I'll keep doing this as long as I have to.  I refuse to end her life becasue this is not convenient to me.  I just ordered the Tinkle Trousers (a larger version of the Pee Keeper), but haven't had the courage to put them on her yet.  But I guess I will have to if I ever want to sleep.  I, too, just wish I knew what was next.  This is just so painful to watch. Debbie MyPeaches Mon, 30 Jan 2012 00:00:00 GMT On Jan 29, 2012 2:26 AM PiccoloMom wrote: Hi everyone, This is Piccolo's mom.  I had to drop out for a week or so to get my "bearings" back.  Most of the time this forum helps but sometimes it is too much for me when I read about the loss of another fight.  I'll bet I'm not alone in this.  Piccolo has been peeing more blood than usual (as in streams), which I know is part of the disease but still makes me revert into "cry" mode.  I was reading one member's post regarding wanting to know "text book" progression and could connect with the sentiment.  Unfortunately, there is no textbook with this cancer- otherwise we'd be closer to a cure.  I've just been relying on my emails and posts with other members to understand what to expect.  To be blunt, it seems we can expect just about anything.  Some members report normal activity and no blood in urine, only to have to say goodbye to their babies shortly after.  Others report streams of blood, lethargy, distressing bloodwork, and coming close to euthanasia, only to have their companions bounce back.  It is SUCH an emotional rollercoaster.  I can go from optimistic to down in the dumps just from changing Piccolo's diaper (lots of red in the pad= panic/ more yellowish urine= cautious contentment).  Lately Piccolo has lots of brown-tinged urine with some red clots.  We have had tests to check kidney function and anemia, and she is fine.  So, once again I feel lulled back into "managing cancer". I take a lot of strength in watching Piccolo.  I have raised her from a puppy and have faith in our ability to communicate with each other.  I believe she will let me know when enough is enough.  So far, her only distress is when I insist on cleaning her ear (she has developed some wart-like growth in one ear that we keep clean and watch) or changing her diaper (The PeeKeeper.com "" target="_blank" rel="nofollow">http://PeeKeeper.com " target="_blank" rel="nofollow">PeeKeeper.com ).  This little dog is so clever, that she knows a diaper change includes a wipe down with lavendar scented baby wipes- which she LOVES.  I love watching her roll over on her back to get her belly wiped down (all the while wagging her tail).  We are all adjusting to the "new normal". My parents, who only have my best interest at heart, have pointed out that the constant need to change diapers, wash her bed linens, and carry Piccolo down to the yard is just "too much work".  They try to insist that Piccolo would be better off if we "put her down".  The thing is, Piccolo still runs around (albeit in a diaper), still gets excited about food, and still plays with her sister.  Piccolo has not shown any signs of pain- she may squat a lot, but she does not seem to be bothered by the incontinence.  So, my answer: Convenience is not a good enough excuse to end her life. Period.  As long as she is fighting, WE are fighting. With love, ChristineDear Christine, Oh dear one, don't let your parents deter you from caring for Piccolo.  It is clear that Piccolo is not ready to leave you yet.  My goodness, if that is the worst you have to do for her, let her be happy as long as she can.  My Chloe wears a Pee Keeper too.  It's no trouble at all.  She doesn't seem to mind it either.  She actually stands and waits for me to put it back on her after coming inside.  As your parents if they considered putting you down when they had to constantly change your diapers and carry you around when you were a baby.  You were worth it and so is Piccolo.  So yes Girlfriend, you keep on fighting as long as she is willing. About the bleeding, by any chance have you had Piccolo's urine cultured to see if there is an infection?  They can do it in the lab without performing a Cysto.  I have had it done with Chloe.  The clots you mention could be that. Hang in there! Heidi and Chloe   MomtoChloe Mon, 30 Jan 2012 00:00:00 GMT On Jan 27, 2012 10:22 PM Nita wrote: To All Members of this Community This thread is for all of us who need info and support to see our dear dogs thru this dreaded disease. Everyone has to make a decision about treatment and no matter which treaent we choose we just have to trust it and go withh it I have chosen chemo , but last time I was waiting in the vets office I spoke with a bet who was conferring with my dogs oncologist about her dog who has a very rare type of cancer. The vet who was on the waiting room with me usually treats tcc with little or no chemo and seems to have very good results in prolonging life with good quality. This disease is torture enough without a feeling that maybe we have made the wrong choice or that others will think less of this for the choices that we made. The thing that we have in common is that we all love our dogs and through no fault of our own we are going thru a very difficult time.Nita, AMEN to that.  What a wonderful post. We HAVE made choices....and guess what!....they were ALL right. I have never seen a wrong choice that was made out of love for your pet. ChicasMom, Lynn   ChicasMom Sun, 29 Jan 2012 00:00:00 GMT To Christine and Chicas Mom, I get a lot out of reading your posts.  You are right about living with "the elephant in the room".  It's so hard, but knowing that others are dealing with it is so helpful.  On a day like today, when the elephant seems particularly massive, I'm going with the  "I sleep, I eat, I poop, I pee, I am loved.. LIFE IS SWEET" in dealing with the disease my dear Rocky is battling.  Thanks,  Nita (Rocky-the dachund's Mom)     Nita Sun, 29 Jan 2012 00:00:00 GMT On Jan 29, 2012 2:12 PM ChicasMom wrote: Hi Christine, I was wondering how you and Piccolo were doing and lo and behold...here you are. You are right.  There is no "textbook" progression in this disease.  I think once I realized this...I got on with living every day trying to keep the "elephant in the room" at bay.  I know what is going to happen but we choose to live each day as normally as possible. Do I wind up in the shower crying sometimes?  Yup, but not as often as I did at first. As long as Piccolo' tests are in the normal range and she is enjoying her life (and not in pain) that's all we can do...manage. That's the norm and we have to get that into our mind set, one day at a time. I have no doubt that your parents are thinking of you (and Piccolo at this point) but in the end you will be happy with yourself for going the limit on taking the best care of Piccolo that you possibly can.  When the end does come (and don't try to kid yourself, it will, everything has a season...yes... even us)...you can look back and say "We did everything in our power to make this little creatures life as comfortable as we could and I am at peace with myself".  If you have done everything that you chose to do, there will be no second guessing, no "could have, would have, should have's".. You will be able to look back, not immediately, but down the road and remember all the GOOD times.  The bad times, the time spent crying, the time spent planning the next step and executing it will only be a memory that you can store somewhere in the back of your mind and heart. I choose to "thumb my nose" at this devil called TCC.  I choose to fight every day for Chica. I choose to keep fighting until there is no more fight left...in her. MY choice!  I'm not going to let TCC alter MY choice while Chica is not in pain and still enjoying her life. Keep loving Piccolo and doing what you have been doing, your best.  There will come a time when you can rest...I'm hoping it's NOT too soon. Give Piccolo (and her sister) a belly rub for us (a treat would probably be greatly appreciated too) and keep up the wonderful care you are giving to her. We have a little saying at our house.... "I sleep, I eat, I poop, I pee, I am loved....LIFE IS SWEET!" ChicasMom, Lynnyou message to chicasmon from christine is remarkable. it gives me hope and drive to live each day to the fullest. having breast ca, stage 4 has become  one day at a time. everyone comments give me hope and inspiration and love. thanks debra hollis40 Sun, 29 Jan 2012 00:00:00 GMT Hi Christine, I was wondering how you and Piccolo were doing and lo and behold...here you are. You are right.  There is no "textbook" progression in this disease.  I think once I realized this...I got on with living every day trying to keep the "elephant in the room" at bay.  I know what is going to happen but we choose to live each day as normally as possible. Do I wind up in the shower crying sometimes?  Yup, but not as often as I did at first. As long as Piccolo' tests are in the normal range and she is enjoying her life (and not in pain) that's all we can do...manage. That's the norm and we have to get that into our mind set, one day at a time. I have no doubt that your parents are thinking of you (and Piccolo at this point) but in the end you will be happy with yourself for going the limit on taking the best care of Piccolo that you possibly can.  When the end does come (and don't try to kid yourself, it will, everything has a season...yes... even us)...you can look back and say "We did everything in our power to make this little creatures life as comfortable as we could and I am at peace with myself".  If you have done everything that you chose to do, there will be no second guessing, no "could have, would have, should have's".. You will be able to look back, not immediately, but down the road and remember all the GOOD times.  The bad times, the time spent crying, the time spent planning the next step and executing it will only be a memory that you can store somewhere in the back of your mind and heart. I choose to "thumb my nose" at this devil called TCC.  I choose to fight every day for Chica. I choose to keep fighting until there is no more fight left...in her. MY choice!  I'm not going to let TCC alter MY choice while Chica is not in pain and still enjoying her life. Keep loving Piccolo and doing what you have been doing, your best.  There will come a time when you can rest...I'm hoping it's NOT too soon. Give Piccolo (and her sister) a belly rub for us (a treat would probably be greatly appreciated too) and keep up the wonderful care you are giving to her. We have a little saying at our house.... "I sleep, I eat, I poop, I pee, I am loved....LIFE IS SWEET!" ChicasMom, Lynn ChicasMom Sun, 29 Jan 2012 00:00:00 GMT All the best to you and to Piccolo!!! Regards Gabriella gabriella68 Sun, 29 Jan 2012 00:00:00 GMT Hi everyone, This is Piccolo's mom.  I had to drop out for a week or so to get my "bearings" back.  Most of the time this forum helps but sometimes it is too much for me when I read about the loss of another fight.  I'll bet I'm not alone in this.  Piccolo has been peeing more blood than usual (as in streams), which I know is part of the disease but still makes me revert into "cry" mode.  I was reading one member's post regarding wanting to know "text book" progression and could connect with the sentiment.  Unfortunately, there is no textbook with this cancer- otherwise we'd be closer to a cure.  I've just been relying on my emails and posts with other members to understand what to expect.  To be blunt, it seems we can expect just about anything.  Some members report normal activity and no blood in urine, only to have to say goodbye to their babies shortly after.  Others report streams of blood, lethargy, distressing bloodwork, and coming close to euthanasia, only to have their companions bounce back.  It is SUCH an emotional rollercoaster.  I can go from optimistic to down in the dumps just from changing Piccolo's diaper (lots of red in the pad= panic/ more yellowish urine= cautious contentment).  Lately Piccolo has lots of brown-tinged urine with some red clots.  We have had tests to check kidney function and anemia, and she is fine.  So, once again I feel lulled back into "managing cancer". I take a lot of strength in watching Piccolo.  I have raised her from a puppy and have faith in our ability to communicate with each other.  I believe she will let me know when enough is enough.  So far, her only distress is when I insist on cleaning her ear (she has developed some wart-like growth in one ear that we keep clean and watch) or changing her diaper (The PeeKeeper.com ).  This little dog is so clever, that she knows a diaper change includes a wipe down with lavendar scented baby wipes- which she LOVES.  I love watching her roll over on her back to get her belly wiped down (all the while wagging her tail).  We are all adjusting to the "new normal". My parents, who only have my best interest at heart, have pointed out that the constant need to change diapers, wash her bed linens, and carry Piccolo down to the yard is just "too much work".  They try to insist that Piccolo would be better off if we "put her down".  The thing is, Piccolo still runs around (albeit in a diaper), still gets excited about food, and still plays with her sister.  Piccolo has not shown any signs of pain- she may squat a lot, but she does not seem to be bothered by the incontinence.  So, my answer: Convenience is not a good enough excuse to end her life. Period.  As long as she is fighting, WE are fighting. With love, Christine PiccoloMom Sun, 29 Jan 2012 00:00:00 GMT To All Members of this Community This thread is for all of us who need info and support to see our dear dogs thru this dreaded disease. Everyone has to make a decision about treatment and no matter which treaent we choose we just have to trust it and go withh it I have chosen chemo , but last time I was waiting in the vets office I spoke with a bet who was conferring with my dogs oncologist about her dog who has a very rare type of cancer. The vet who was on the waiting room with me usually treats tcc with little or no chemo and seems to have very good results in prolonging life with good quality. This disease is torture enough without a feeling that maybe we have made the wrong choice or that others will think less of this for the choices that we made. The thing that we have in common is that we all love our dogs and through no fault of our own we are going thru a very difficult time. Nita Fri, 27 Jan 2012 00:00:00 GMT I considered chemo, but decided against it for several reasons (money was not one of them).  Peaches is terrified to go to the vets office, so I have a mobile vet come to my house to take her blood and urine every month, then he send the results to her oncologist.  I was not going to torture her further by taking her to the vets office for chemo repeatedly for 6 months when the oncologist told me that chemo will probably only add 6-12 months to her life.  I can give her Piroxicam in her own home and not stress her out by going to the vet.  She was diagnosed 20 months ago, and I was told the median expectancy for the disease was 6-12 months, so I consider myself blessed for having her almost 2 years after diagnosis.  Piroxicam is working, but nothing can "cure" this disease.  MyPeaches Fri, 27 Jan 2012 00:00:00 GMT Yes, I think there are things that typically happen in the progression of this disease.  When I rushed my dog to  emergency vet because I was fully convinced that she was hemorraging to death, I was told that it was simply the tumor bleeding and that I should have been told to expect something like this. So YES apparently there ARE some things that should be expected.  I am not "just sitting around waiting for the progression" as you so callously insinuated.  My dog is being treated,  just not with chemo drugs.  I'm glad it's working out for you and hope for the best, but it's not for every situation.  And get your grammar right - it should be "those are the choices we are facing" or "that is the choice we are facint." .  And please tell me,  how would you even know that if there wasn't something "textbook" out there?  totaldweeb Fri, 27 Jan 2012 00:00:00 GMT Do you actually think there is a "textbook example" of the progression? If you read all of the info on these message boards, you will find dogs that have died after 8 weeks to living 3 to 4 years. Everyone has done different things so there is no way of knowing what might work for one may not work for another. Just the same as in humans. There is no way of knowing. We just have to take all the info and try to help them the best we can. My dog is currently taking chemo, meloxicam and hyperthermia heat treatments to the bladder area. She does not appear to be suffering and after her next ultrasound we will see if there is any changes in the tumor. I' just not going to set around waiting for the progression whatever it may be. When the Drs. say there is nothing else they can do then i will start with all the information I have gathered from these message boards and start different things on my own. I know if it gets to the point of her not being able to pee, that will be an emergency. I will either have to go with stents and other invasive treatment or have her put down. That is the choices we are facing. Chloebeaglemom Fri, 27 Jan 2012 00:00:00 GMT The symptoms you describe could be either UTI or the disease...that's the hard part about all of this. Since your dog's last ultrasound was August, you may want to consider another one.  My dog has an ultrasound every 3 or 4 months to keep tabs.  The other thing to try first maybe is to get a urine culture and make sure the bacteria she has can be treated with Cipro.  Bailey has had 4 infections the last year and has been on different antibiotics depending on the culture. There was a link to an article about TCC on the message board and this gives some idea about the disease.  Also, Dr. Cerf has a blog about TCC on his website if you google Ridgewood Veterinary Hospital and then look for TCC on his site.  Hope this helps. Baileysmom97 Thu, 26 Jan 2012 00:00:00 GMT In Bailey's case, you would never know she has a UTI.  There was only one time where there was some blood.  The bleeding can be from the disease and I guess the frequency as well.  I think you just have to monitor the habits and see when things begin to change.  We've only discovered the UTI's on our regular check-ups.  In September, the doctor was ready to tell us come back in 5 months until her bloodwork came back a bit off.  I would probably ask your vet about whether the green tea would interfere with the chemo, but it doesn't seem likely that it would. Baileysmom97 Thu, 26 Jan 2012 00:00:00 GMT On Jan 23, 2012 10:44 PM livininca06 wrote: On Jan 22, 2012 5:04 PM totaldweeb wrote: On Dec 19, 2011 4:45 PM MyPeaches wrote: Im hoping someone can give me advice on what is currently going on with Peaches.  She has had bladder cancer for 1 1/2 years now.  She has been on Piroxicam and recently I have added Tramadol when I believe she is uncomfortable (I wish they could speak!). About 4 weeks ago, she started peeing blood.  I took her to the vet and they said she could possibly have a UTI which is common with this disease.  She took Cipro for 10 days and it did not clear up the blood.  I called the vet again and told her besides her peeing blood, she seems to be straining to pee and peeing frequently.  She will go outside to pee, then come back in the house and pee again in 10 minutes.  Her urine is not just tainted with blood, it is completely red.  The vet put her on Cipro again, and she is just finishing the 2 week dose, and her symptoms are still the same.  The vet says this is just her disease progressing, and this may never clear up.  Has anyone else seen this in their dog, and if so, what else can be done? My vet is telling me there is nothing else I can do to relieve her besides the Piroxicam and Tramadol.  There has to be something else I can do for her.  Her last ultrasound in Aug showed that her original tumor has grown to over 2 cm, and now there are more tumors in her bladder.  Is she just going to continue to be uncomfortable and have to pee frequently the rest of her life?  I have had UTI's before, and I know how horrible they are.  I don't know what to do.  Any advice would be greatly appreciated!Wish I could help but I'm just as lost and confused and distressed as you sound.  My dog is going through something similar.   She was diagnosed in September and just yesterday started passing solid streams of blood.  It was terrifying.  I thought she was hemorraging so I rushed her to the emergency vet only to be told that it was a normal progession of the cancer but that it would stop.  She doesn't seem to be in any pain - she is wagging her tail happpily and scarfing down food like they're never going to make any more, but dang - what's next?  Wish they would tell us what to expect. I'm trying to take it a day at a time and enjoying every minute with her but it would be nice not to have these unpleasant (and expensive) surprises.  Does anyone know of a clinical description that describes the "textbook" example of the progression of this cancer?  Have either of you considered chemo?Considered and rejected chemo.  She's been through enough already.  Thanks for the non-answer though.  totaldweeb Thu, 26 Jan 2012 00:00:00 GMT Hi, Karin, I was wondering how do you know if there is a UTI or if the bleeding and frequent urination are just a result of the disease itself.  My dog had stopped bleeding altogether, but I noticed a little blood and straining over the weekend.  He seems to have gotten over that on his own, but other than taking him in for a urinalysis, I didn't know how to determine what was going on. Also, does anyone know if green tea can be used during chemo? Iloverio Thu, 26 Jan 2012 00:00:00 GMT Hi Barbara--Bailey just turned 14 in December.  It is an awful disease but I count my blessings because all in all, she is doing pretty well.  It is very strange with her peeing habits.  During the day she goes every 3 or 4 hours, but at night it seems to be every hour after she eats.  I had trained her as a puppy on wee wee pads so at night she can just go on the pad.  Sometimes she leaks at night and other times not...there does not seem to be any rhyme or reason why.  Bailey does not drip while on the way out and seems to have a very steady stream with no problems of stopping and going.  The only thing I will say is that she seems to have more frequency of having to go when she has a UTI going on.  This is now her 4th infection in less than a year.  She's been on antibiotics for almost a month now because the first go-around didn't clear up the infection.  We'll be going for a re-check next week but they may still want to keep her on antibiotics for another 3 weeks!  We got really lucky with where the tumor is and it was discovered quite early.  Bailey's tumor is in an area which does not interfere either with the kidneys or the urethra so she's got that going for her.  Also, her 2nd ultrasound in March of last year, showed a 2nd smaller tumor at the urethra.  After a month of the piroxicam and green tea, her doctor at UPenn could find no evidence of the 2nd tumor!   I think the green tea definitely helps...Bailey was actually off the piroxicam for about two months because they thought it was affecting her kidneys.  Her doctor was super excited upon her last ultrasound because she thought the tumor was fairly stable in size.  Right now, she only takes the piroxicam every other day but the green tea she still takes 2 each day.  I also met a woman at UPenn whose dog had TCC and lived 5 years with it only being treated with an anti-inflammatory!  I guess it all depends.  UPenn did recommend chemo but I did not want to put Bailey through that, although I understand that most dogs handle the chemo extremely well.  As crazy as this sounds, I don't think the cancer seems to affect her as much as the UTI's.  She sleeps a bit more but she still acts like a puppy at other times.  Her appetite is great and we try to go still for long walks on the weekend...she even did a two-hour hike on New Year's Day!  Please don't hesitate to ask me any other questions.  I am happy to help as much as I can and hope we can all help each other beat this disease.  Good luck to you and Molly. Karin   Baileysmom97 Thu, 26 Jan 2012 00:00:00 GMT On Jan 20, 2012 11:25 PM Baileysmom97 wrote: Hi Barbara-- My dog Bailey was diagnosed with TCC about a year ago.  She is on Piroxicam, Pepcid and green tea extract (brand name of Teavigo which seems to be most pure EGCG).  I would definitely recommend the green tea...I've read some good studies where they have shown green tea to have results similar to some chemo drugs and Bailey is doing pretty well all things considered.  The Teavigo is very pure EGCG (green tea) and comes in a relatively small capsule which I stick in a piece of meatball.  You can also get fish oil capsules and do the same.  I know with Bailey, if I try to put it directly on her food she won't eat it.  Give the green tea a shot...it seems to be working with Bailey and even the Doctor at UPenn is recommending it to her patients!Hi.  I'm sorry to hear about Bailey.  It's such an awful disease that our poor babies have to endure.  How old is Bailey and have they done anything else besides Piroxicam, Pepcid and green tea? That is amazing that Bailey has been able to endure this for a year.  I was wondering if she has to urinate a lot and does she drip urine on the way out to go and stop several times to complete the peeing?  My Molly urinates about every hour or two and if I don't run to the door fast enough to let her out, she starts going on the floor.  I know I'm asking a lot of questions, but I was also wondering where the mass is on Bailey.  Molly's is at the neck of the bladder.  I hope you have a moment to get back to me because your information about the green tea is very promising and I'd love to hear more about your success. With gratitude for your concern and feedback, Barbara, Molly's mom barbef Wed, 25 Jan 2012 00:00:00 GMT On Jan 23, 2012 11:41 PM Baileysmom97 wrote: The brand is Teavigo and a few companies provide it.  The one I get is from Healthy Origins and I order it from IHerb.com "" target="_blank" rel="nofollow">http://IHerb.com " target="_blank" rel="nofollow">IHerb.com .  Dr. Cerf originally prescribed it for Bailey and her dosage was 200mg per day and she was 13 pounds at that time.  The capsules I get now are about 135mg per capsule and she still takes 2 per day without any problems.  I would guess maybe 100mg per 6.5 to 7 pounds of body weight.  I originally got it from Dr. Cerf's office but she is no longer treated at his office...I go to UPenn.  Dr. Cerf also has a website and I think he also has some cancer discussions and helpful advice.  You could probably find it through the Ridgewood Veterinary Hospital website. Also, for anyone having upset stomach problems with antibiotics, I am giving Bailey some pro-biotic supplements with her food and it definitely seems to be helping.Bless you!  Thanks so much! Hugs, Heidi and Chloe   MomtoChloe Tue, 24 Jan 2012 00:00:00 GMT On Jan 23, 2012 11:41 PM Baileysmom97 wrote: The brand is Teavigo and a few companies provide it.  The one I get is from Healthy Origins and I order it from IHerb.com "" target="_blank" rel="nofollow">http://IHerb.com " target="_blank" rel="nofollow">IHerb.com .  Dr. Cerf originally prescribed it for Bailey and her dosage was 200mg per day and she was 13 pounds at that time.  The capsules I get now are about 135mg per capsule and she still takes 2 per day without any problems.  I would guess maybe 100mg per 6.5 to 7 pounds of body weight.  I originally got it from Dr. Cerf's office but she is no longer treated at his office...I go to UPenn.  Dr. Cerf also has a website and I think he also has some cancer discussions and helpful advice.  You could probably find it through the Ridgewood Veterinary Hospital website. Also, for anyone having upset stomach problems with antibiotics, I am giving Bailey some pro-biotic supplements with her food and it definitely seems to be helping.Sorry, I should have changed to the subject line. Baileysmom97 Mon, 23 Jan 2012 00:00:00 GMT The brand is Teavigo and a few companies provide it.  The one I get is from Healthy Origins and I order it from IHerb.com .  Dr. Cerf originally prescribed it for Bailey and her dosage was 200mg per day and she was 13 pounds at that time.  The capsules I get now are about 135mg per capsule and she still takes 2 per day without any problems.  I would guess maybe 100mg per 6.5 to 7 pounds of body weight.  I originally got it from Dr. Cerf's office but she is no longer treated at his office...I go to UPenn.  Dr. Cerf also has a website and I think he also has some cancer discussions and helpful advice.  You could probably find it through the Ridgewood Veterinary Hospital website. Also, for anyone having upset stomach problems with antibiotics, I am giving Bailey some pro-biotic supplements with her food and it definitely seems to be helping. Baileysmom97 Mon, 23 Jan 2012 00:00:00 GMT On Jan 22, 2012 5:04 PM totaldweeb wrote: On Dec 19, 2011 4:45 PM MyPeaches wrote: Im hoping someone can give me advice on what is currently going on with Peaches.  She has had bladder cancer for 1 1/2 years now.  She has been on Piroxicam and recently I have added Tramadol when I believe she is uncomfortable (I wish they could speak!). About 4 weeks ago, she started peeing blood.  I took her to the vet and they said she could possibly have a UTI which is common with this disease.  She took Cipro for 10 days and it did not clear up the blood.  I called the vet again and told her besides her peeing blood, she seems to be straining to pee and peeing frequently.  She will go outside to pee, then come back in the house and pee again in 10 minutes.  Her urine is not just tainted with blood, it is completely red.  The vet put her on Cipro again, and she is just finishing the 2 week dose, and her symptoms are still the same.  The vet says this is just her disease progressing, and this may never clear up.  Has anyone else seen this in their dog, and if so, what else can be done? My vet is telling me there is nothing else I can do to relieve her besides the Piroxicam and Tramadol.  There has to be something else I can do for her.  Her last ultrasound in Aug showed that her original tumor has grown to over 2 cm, and now there are more tumors in her bladder.  Is she just going to continue to be uncomfortable and have to pee frequently the rest of her life?  I have had UTI's before, and I know how horrible they are.  I don't know what to do.  Any advice would be greatly appreciated!Wish I could help but I'm just as lost and confused and distressed as you sound.  My dog is going through something similar.   She was diagnosed in September and just yesterday started passing solid streams of blood.  It was terrifying.  I thought she was hemorraging so I rushed her to the emergency vet only to be told that it was a normal progession of the cancer but that it would stop.  She doesn't seem to be in any pain - she is wagging her tail happpily and scarfing down food like they're never going to make any more, but dang - what's next?  Wish they would tell us what to expect. I'm trying to take it a day at a time and enjoying every minute with her but it would be nice not to have these unpleasant (and expensive) surprises.  Does anyone know of a clinical description that describes the "textbook" example of the progression of this cancer?  Have either of you considered chemo? livininca06 Mon, 23 Jan 2012 00:00:00 GMT Hi baileys mom...a few of us on here are wondering if you could please tell us where you get the tevigo products and exactly what the product name is and the dosage your dog is taking is. there are a few out there and we are unable to figure out which one your dog is taking. also if you could let us know the type/weight of your dog, maybe we could figure out dosage for ours. Thank you, at this point I am sure we are all so desperate for any help we can get! bailey661 Mon, 23 Jan 2012 00:00:00 GMT Hi Susan,   I found this article and found it interesting, but it doesn't list a specific brand name or dosages: EGCG and dog cancer: beyond chemo, radiation and surgery byDr. Demian Dressler·7 comments So you feel that there is more than chemotherapy, radiation and surgery for dogs with cancer? So do I, and we are correct! Here’s just one example: EGCG (epigallocatechin-3-gallate). This is a naturally occurring substance found in green tea.   EGCG has several anticancer effects that are very real.  This substance is in trials at the Mayo Clinicdue to its beneficial effects in human cancers. Here is the skinny: In mice, it has been shown to inhibit mammary cancer growth and spread. In the samestudyit was also been shown to shrink these tumors. EGCG has also been shown to cause apoptosis of sarcoma cells (programmed cell death), and cell cycle arrest (stopping the cancer cells from growing). Here is thelink.Simila r findingsin mice were found using prostate cancer tumors, which shrank when the mice were given this compound. In addition, when EGCG was combined with other drugs for cancer (COX-2 inhibitors, like piroxicam commonly used for transitional cell bladder cancer in dogs), less of these other drugs could be used, with greater effect.  Check it out. The benefit: since these drugs had side effects, one could lower the chances of side effects with less drug by adding EGCG to the regimen. There are also gobs of test tube studies supporting EGCG’s effect against cancer cells of various kinds. Pundits will say…well, those are only mice!  Not dogs!  Okay, okay.  But dogs and mice are a lot closer than humans and mice, and the Environmental Protection Agency uses mice to assess whether or not something causes cancer in people.  Next,  they pass laws based on that assumption..so the rodent model has validity!! And the diligence crew will go out and find a study that was done on dogs available on line that ended up with a bunch of dead beagles at the end of the study.  First of all, the authors of this study should be ashamed of themselves.  They used amounts in the ballpark of one hundred times the standard EGCG supplement amounts for weeks on end and killed these dogs.  What is the point? I was aghast after reading this. Yes, drink a hundred glasses of wine a day, drink a hundred cups of coffee a day, you will die too.  Unbelieveable. Sorry for the rant but this was an agenda-oriented study that served no good use and is really upsetting. Anyway, if you feel you have too few options, EGCG is one (of many) that may help prolong your dogs life and keep it at good quality.  A new source of purified EGCG is becoming available called Teavigo.  Talk to your vet after presenting the info I cited here. CAUTION: do NOT give your dog tea extracts that contain the stimulants that are naturally found therein! Caffeine and methylxanthines in tea can be toxic to dogs! Consult with your vet before embarking on any treatment plan.   Hopefully, we will hear back from the person who is using it on her dog. Hugs to all, Heidi and Chloe   MomtoChloe Mon, 23 Jan 2012 00:00:00 GMT I have been waiting for someone to answer this question for me also. Im like you, there are several different kinds of teavigo green tea out there. Where do they get it and what would the doses be per pound. Would someone let us know? Thanks, ChloebeagleMom Susan Chloebeaglemom Mon, 23 Jan 2012 00:00:00 GMT On Jan 20, 2012 11:25 PM Baileysmom97 wrote: Hi Barbara-- My dog Bailey was diagnosed with TCC about a year ago.  She is on Piroxicam, Pepcid and green tea extract (brand name of Teavigo which seems to be most pure EGCG).  I would definitely recommend the green tea...I've read some good studies where they have shown green tea to have results similar to some chemo drugs and Bailey is doing pretty well all things considered.  The Teavigo is very pure EGCG (green tea) and comes in a relatively small capsule which I stick in a piece of meatball.  You can also get fish oil capsules and do the same.  I know with Bailey, if I try to put it directly on her food she won't eat it.  Give the green tea a shot...it seems to be working with Bailey and even the Doctor at UPenn is recommending it to her patients!Hi Baileysmom,   I am also interested in the Green Tea.  I searched google for it and the Teavigo is available in alot of brands.  I would like to use the one you are using.  Can you please tell me where you got it and what it is called?  My Chloe is a Westie who weighs about 17 pounds.  She was diagnosed 2/2/11 and we were told she would have only 5 months to live.  She has proved them wrong.  We have not done chemo.  She is on Piroxicam and Pepcid AC. Thank you! Heidi and Chloe   MomtoChloe Mon, 23 Jan 2012 00:00:00 GMT On Dec 19, 2011 4:45 PM MyPeaches wrote: Im hoping someone can give me advice on what is currently going on with Peaches.  She has had bladder cancer for 1 1/2 years now.  She has been on Piroxicam and recently I have added Tramadol when I believe she is uncomfortable (I wish they could speak!). About 4 weeks ago, she started peeing blood.  I took her to the vet and they said she could possibly have a UTI which is common with this disease.  She took Cipro for 10 days and it did not clear up the blood.  I called the vet again and told her besides her peeing blood, she seems to be straining to pee and peeing frequently.  She will go outside to pee, then come back in the house and pee again in 10 minutes.  Her urine is not just tainted with blood, it is completely red.  The vet put her on Cipro again, and she is just finishing the 2 week dose, and her symptoms are still the same.  The vet says this is just her disease progressing, and this may never clear up.  Has anyone else seen this in their dog, and if so, what else can be done? My vet is telling me there is nothing else I can do to relieve her besides the Piroxicam and Tramadol.  There has to be something else I can do for her.  Her last ultrasound in Aug showed that her original tumor has grown to over 2 cm, and now there are more tumors in her bladder.  Is she just going to continue to be uncomfortable and have to pee frequently the rest of her life?  I have had UTI's before, and I know how horrible they are.  I don't know what to do.  Any advice would be greatly appreciated!Wish I could help but I'm just as lost and confused and distressed as you sound.  My dog is going through something similar.   She was diagnosed in September and just yesterday started passing solid streams of blood.  It was terrifying.  I thought she was hemorraging so I rushed her to the emergency vet only to be told that it was a normal progession of the cancer but that it would stop.  She doesn't seem to be in any pain - she is wagging her tail happpily and scarfing down food like they're never going to make any more, but dang - what's next?  Wish they would tell us what to expect. I'm trying to take it a day at a time and enjoying every minute with her but it would be nice not to have these unpleasant (and expensive) surprises.  Does anyone know of a clinical description that describes the "textbook" example of the progression of this cancer?   totaldweeb Sun, 22 Jan 2012 00:00:00 GMT On Jan 21, 2012 1:52 AM Chloebeaglemom wrote: Where did you get your green tea and what mg do you give Bailey. How much does she weigh? Chloe is 32 lbs. just trying to get a comparison so I would know how much and how often to give it. Thanks Chloe's momMy dog bailey is 32 lbs as well and i am looking for the correct green tea dosage. Any help would be greatly appreciated! Thanks!! bailey661 Sun, 22 Jan 2012 00:00:00 GMT Where did you get your green tea and what mg do you give Bailey. How much does she weigh? Chloe is 32 lbs. just trying to get a comparison so I would know how much and how often to give it. Thanks Chloe's mom Chloebeaglemom Sat, 21 Jan 2012 00:00:00 GMT Hi Barbara-- My dog Bailey was diagnosed with TCC about a year ago.  She is on Piroxicam, Pepcid and green tea extract (brand name of Teavigo which seems to be most pure EGCG).  I would definitely recommend the green tea...I've read some good studies where they have shown green tea to have results similar to some chemo drugs and Bailey is doing pretty well all things considered.  The Teavigo is very pure EGCG (green tea) and comes in a relatively small capsule which I stick in a piece of meatball.  You can also get fish oil capsules and do the same.  I know with Bailey, if I try to put it directly on her food she won't eat it.  Give the green tea a shot...it seems to be working with Bailey and even the Doctor at UPenn is recommending it to her patients! Baileysmom97 Fri, 20 Jan 2012 00:00:00 GMT On Jan 20, 2012 2:33 PM tmfaubus wrote: Dogs ?? Here I am with a terminal brain tumor...wow.  I hear ya! ohd1974 Fri, 20 Jan 2012 00:00:00 GMT On Jan 20, 2012 2:33 PM tmfaubus wrote: Dogs ?? Here I am with a terminal brain tumor...wow.  Hi tmfaubus, I don't think you've realized it, but you posted in the "Canine Bladder Cancer TCC" forum. We're a support group for each other as we help our companions fight cancer, while retaining quality of life. I am so sorry for your illness- cancer in all forms is such a terrible disease. My father has found a forum on this site for prostate cancer, and he's learning more about treatments/nutrition/staying positive each time he tunes in. I hope you can find a forum more specific to your type of cancer. I've found everyone to be compassionate, helpful, and ready to lend emotional support on those particularly terrible days. Very best, Christine PiccoloMom Fri, 20 Jan 2012 00:00:00 GMT Hi, I don't think you've realized it, but you posted in the "Canine Bladder Cancer TCC" forum. We're a support group for each other as we help our companions fight cancer, while retaining quality of life. I am so sorry for your illness- cancer in all forms is such a terrible disease. My father has found a forum on this site for prostate cancer, and he's learning more about treatments/nutrition/staying positive each time he tunes in. I hope you can find a forum more specific to your type of cancer. I've found everyone to be compassionate, helpful, and ready to lend emotional support on those particularly terrible days. Very best, Christine PiccoloMom Fri, 20 Jan 2012 00:00:00 GMT Hi Barbara! Yes, I am very blessed that I still have Ripley with me after a year of fighting TCC. We haven't had many ups and downs. The first chemo drug we tried didn't work and he developed a new tumor that blocked his kidney. We anticipated that his kidney would die but after switching to another drug that tumor basically went away and his kidney worked normally. We haven't had any issues with peeing...he doesn't pee blood or strain to pee or even have to pee a lot. We did have a setback last week because he has a couple new small tumors so now we have to switch chemo drugs. I haven't read many past posts but have you considered chemo? I think chemo has given me this time with him and with a good quality of life. Amy livininca06 Fri, 20 Jan 2012 00:00:00 GMT Wow!  Never even thought of Walmart!! Thank you. ChicasMom, Lynn ChicasMom Fri, 20 Jan 2012 00:00:00 GMT Yes I know about the silica and also lecithin. Neither one should be given to a dog. I found one at Walmart that is just cranberry powder, no fillers. Chloebeaglemom Fri, 20 Jan 2012 00:00:00 GMT Hi Susan, When I was about to go to cranberry powder (I thought I had researched the heck out of it and picked one that I thought was right for us) I took the ingredient list (from the mfg) to Chica's oncologist (who conferred with IM). Well was I ever suprised to find that the one I choose had SILICA in it. This usually shows up in "other ingredients". I was informed that silica causes stones (ARGGGH) and at this point we did not need any more problems. On closer inspection of the other products that were on my list...many had silica in them. I was so snowed by the other good ingredients that I didn't even think that there would be something in there that wasn't good. That's not to say that there are not any without silica...there are. Chica's oncologist suggested Cranadin (RX)...so we are trying that, but there are more out there than just this one. I'm still researching to find something not RX to switch to...hopefully less expensive. What are you using? Check your label and check with Chloe's vet/oncologist. You are taking really good care of Chloe with diet and other things that just one more check would be worth it. Hoping for the best for Chloe on the upcoming ultrasound. ChicasMom, Lynn ChicasMom Fri, 20 Jan 2012 00:00:00 GMT Dogs ?? Here I am with a terminal brain tumor...wow.   tmfaubus Fri, 20 Jan 2012 00:00:00 GMT Sorry to hear about another dog with dreaded disease. It seems our Beagles are kinda young to have this. Chloe did well on her first chemo last week. she will have it every 3 weeks. I hope her second one goes well too but I'll have to wait & see. Once a week we are doing a treatment called hyperthermia. They put a pad on her bladder area for 50 min. that delivers microwave heat to the tumor area. It is suppose to kill off the cancer cells. She also takes meloxicam instead of piroxicam. We are working with an oncologist that taught and did research at the University of Tennessee vet school. I have changed her food to Blue Buffalo wilderness, salmon with high protein, no grains. It still has some complex carbs. Chloe weighs 32 lbs. so she has no problem eating. I am also givivng her cooked chicken, yogurt , cottage cheese and green beans ( not everyday and not at the same time) I have added cranberry powder, salmon oil and Ester-c. Just research I have done on my own. I will talk to the Dr. this morning when we go for the heat treatment about the things I am giving her. So far you cannot tell anything is wrong with her unless you watch her go pee. She squats atleast 4 times. I can't take her for a walk because she has to stop constantly. She has never peed blood. It sounds like things can get a lot worse If this tumor continues to grow. Stay in touch and let me know Emily is doing. Has her tumor shrunk with the chemo and meds? We will be doing an ultra sound in about 5 more weeks to see how things look? I think we can all help each other. Susan, Chloe's mom Chloebeaglemom Fri, 20 Jan 2012 00:00:00 GMT On Jan 20, 2012 10:03 AM LittleKaren wrote: Susan, I had to respond as I have a sweet almost 7 year beagle, Emily, who was also recently diagnosed with TCC. She too does not do well with separation, but we worked with a trainer and crate her. She LOVES her crate. We are currently living in Zurich, Switzerland and it has been difficult because we found out 3 weeks after moving here that Em had TCC. We went through 4 rounds of chemo, what they recommend here, and we are sticking with the Piroxicam and the maintainence dosage of the chemo. She did great on the first round of chemo, but got really sick ont the second round. She refused food-as you know very upsetting for a beagle owner! She even lost hair on her snout. She did so well on the first round they stuck with the same level, but the second round was too much. We lowered the dose and she did fine the rest of time. She was tired and not as thrilled to eat, usually for the second and third day after. The first day after she slept, but still ate. I have been following Dr. D. Dressler's Dog Cancer Survival Diet and read his book. I haven't bought the Apocaps as I read they are not to be taken with NSAIDs and that is the Piroxicam. But Emily LOVES the food I cook for her and it makes me feel like I am doing what Chica's mom suggested, fighting! It does have some rice, but he explains all the ingredients and why he recommends what he does. I use Orijen pet food, made by the same folks who make Arcana. No corn or wheat and high proteins. The food I cook for her based on Dr. Dresslers diet combines lots of meat, cottage cheese, fish or krill oil, veggies and rice. Emily loves it and goes crazy to eat, so right now I'm sticking with it. He also recommends enzymes-I think Chica's mom use some also-to help the pup better digest and get all the nutrients out of the food. It seems to help her not have loose stools. I have noticed a difference. Then there are supplements are add ins like ginger. One thing I was not sure about, Emily doesn't take an antacid with the Piroxicam. I put the compounded formula into her food in the evening. She eats and doesn't vomit, so I guess she's tolerating it, but wondered about others and what you use? She weighs 26 pounds but I wasn't sure about dose? Thanks to all for all the information. I am upset, but it helps to know what to look for as the disease progresses and the ways you all have adapted! Karen, Emily and Murphy's momHi Karen, You are doing just great on the food front. Keep Emily eating, once they become finicky about food or (god forbid, water) it's an uphill battle. Murphy will not suffer with the diet you are providing Emily...he might even prosper. What you probably need to do (because she seems to be tolerating Piroxicam) is make sure she "doesn't" aquire a problem. Vomiting is not the problem....vomiting blood is a very large problem that will require you to stop the Piroxicam and treat for an ulcer (remembering that the Piroxicam is for treating the tumor(s)). We have been using misoprostol (1 hr before Piroxicam) since 2009 without incidence. Others on this board have used sucralfate (Carafate) with the same results. I'm not sure how much sucralfate is but I do know misoprostol is very expensive (especially if it has to be compounded). Take one day at a time. Do the same thing...that worked the day before...again...and every day thereafter. When it seems not to work for Emily...be creative and try new things to entice her. We can only do our best. Sometimes our best doesn't seem like enough but if you know in your heart that you gave it your all...you have achieved. Take care of Emily and Murphy, love them a lot, and for goodness sake take care of yourself, so you can sustain the fight. ChicasMom, Lynn ChicasMom Fri, 20 Jan 2012 00:00:00 GMT Susan, I had to respond as I have a sweet almost 7 year beagle, Emily, who was also recently diagnosed with TCC. She too does not do well with separation, but we worked with a trainer and crate her. She LOVES her crate. We are currently living in Zurich, Switzerland and it has been difficult because we found out 3 weeks after moving here that Em had TCC. We went through 4 rounds of chemo, what they recommend here, and we are sticking with the Piroxicam and the maintainence dosage of the chemo. She did great on the first round of chemo, but got really sick ont the second round. She refused food-as you know very upsetting for a beagle owner! She even lost hair on her snout. She did so well on the first round they stuck with the same level, but the second round was too much. We lowered the dose and she did fine the rest of time. She was tired and not as thrilled to eat, usually for the second and third day after. The first day after she slept, but still ate. I have been following Dr. D. Dressler's Dog Cancer Survival Diet and read his book. I haven't bought the Apocaps as I read they are not to be taken with NSAIDs and that is the Piroxicam. But Emily LOVES the food I cook for her and it makes me feel like I am doing what Chica's mom suggested, fighting! It does have some rice, but he explains all the ingredients and why he recommends what he does. I use Orijen pet food, made by the same folks who make Arcana. No corn or wheat and high proteins. The food I cook for her based on Dr. Dresslers diet combines lots of meat, cottage cheese, fish or krill oil, veggies and rice. Emily loves it and goes crazy to eat, so right now I'm sticking with it. He also recommends enzymes-I think Chica's mom use some also-to help the pup better digest and get all the nutrients out of the food. It seems to help her not have loose stools. I have noticed a difference. Then there are supplements are add ins like ginger. One thing I was not sure about, Emily doesn't take an antacid with the Piroxicam. I put the compounded formula into her food in the evening. She eats and doesn't vomit, so I guess she's tolerating it, but wondered about others and what you use? She weighs 26 pounds but I wasn't sure about dose? Thanks to all for all the information. I am upset, but it helps to know what to look for as the disease progresses and the ways you all have adapted! Karen, Emily and Murphy's mom LittleKaren Fri, 20 Jan 2012 00:00:00 GMT On Jan 19, 2012 4:48 PM Iloverio wrote: Don't hesitate to ask me anything.  I can relate about you and your husband disagreeing,  My husband and I don't agree on all aspects of Rio's treatment, and I have to sit back and take time to explain and then he will come to a decision.  Men are much more logical and reason things like, "Healthy humans usually outlive their pets."  "The pet had a good life, and maybe this is his or her transition."  I have heard all of that from my husband.  On some level, I know of course he is right.  But I so desperately want to nurture my dog and keep him happy for as long as I can.  The stent is expensive -- it will cost between $2K and $3K.  It is not guaranteed -- but they are usually honest about what they perceive to be the outcome.  But if your dog is 12, I am not sure if I would go ahead with any of the procedures.   I have spent all my discretionary income on Rio in the last 4 months.  We are empty nesters, so I can chose to do that.  You have other prioroities, and your dog understands that and loves you.  It sounds to me like you have been an exceptional pet owner.  One thing you could do is ask your vet about clinical trials for stents.  We couldn't get into one, but the opportunities change all the time.  Also, I would invstigae Graviola and green tea extract that a lot of the posters are using.  I don't things those are as costly as RX meds.  Take care and keep my posted.Once again thank you for your kind words. It's so nice to know there are people out there that understand. I think you're right about the stent at Molly's age. Any surgery for a dog of 12 is pretty risky. At this point I have a laundry list of herbs/vitamins, etc I will check on with the vet next Wednesday. They never once mentioned anything to me besides the piroxicam and antacid. I wish they would have suggested other things and since I've been so numb I just recently began looking things up on the net.  I wish I would have started the search earlier. I guess I was afraid of what I would find. I was also wondering how some of these supplements get added to the dog's food.  If they smell or taste weird, I cant imagine Molly taking it.  All the sights mention fish oil but when I tried to give her salmon she turned away in disgust.  I guess I can just try everything in hopes she'll take it. Anyway, thanks to you again for your continued support and feedback. Barbara barbef Fri, 20 Jan 2012 00:00:00 GMT Hi, this is Nita.  I have a ten year old standard dachshund named Rocky who was diagnosed with TCC last summer. First, I'm so sorry that you are going through this with Rio.  It is so good to be able to share therapies and moral support for our beloved dogs, but also so sad to hear from so many loving people who are fantastic companion people to their dogs and the emotional suffering that accompanies this disease.  We live on a golf course, too.  I have been trying to find the last research regarding environmental toxins and TCC.  I know the early studies pointed to a relationship, but I was under the impression that later work wasn't as clear.  Don't get me wrong,  I hate pesticides and insecticides and last spring spend hours of backbreaking work trying to get dandelions by hand (and paid professionals to do the same) so that we sould have a pesticide free lawn, although our neighbors use poisons and I know that the golf course we're on does too.   It certainly does seem strange about the golf course connection.  Please let me know when you find our if they use chemicals on yours and what kind.   Rocky is on the standard treatment for TCC.  I'll be meeting with my vet-- who is into a combination of traditional and complementary medicine-- and I'll pass along any suggestions to this site.  The mushroom drops seem interesting to me because I know that some people doctors are into mushroom, both for the "meaty" texture and the anti cancer benefits. Nita Thu, 19 Jan 2012 00:00:00 GMT Don't hesitate to ask me anything.  I can relate about you and your husband disagreeing,  My husband and I don't agree on all aspects of Rio's treatment, and I have to sit back and take time to explain and then he will come to a decision.  Men are much more logical and reason things like, "Healthy humans usually outlive their pets."  "The pet had a good life, and maybe this is his or her transition."  I have heard all of that from my husband.  On some level, I know of course he is right.  But I so desperately want to nurture my dog and keep him happy for as long as I can.  The stent is expensive -- it will cost between $2K and $3K.  It is not guaranteed -- but they are usually honest about what they perceive to be the outcome.  But if your dog is 12, I am not sure if I would go ahead with any of the procedures.   I have spent all my discretionary income on Rio in the last 4 months.  We are empty nesters, so I can chose to do that.  You have other prioroities, and your dog understands that and loves you.  It sounds to me like you have been an exceptional pet owner.  One thing you could do is ask your vet about clinical trials for stents.  We couldn't get into one, but the opportunities change all the time.  Also, I would invstigae Graviola and green tea extract that a lot of the posters are using.  I don't things those are as costly as RX meds.  Take care and keep my posted. Iloverio Thu, 19 Jan 2012 00:00:00 GMT Barbara, It's "SPEAKING FOR SPOT". I don't know why the computer put it the way it did.  Mind of it's own...I guess. ChicasMom, Lynn ChicasMom Thu, 19 Jan 2012 00:00:00 GMT On Jan 19, 2012 2:10 PM barbef wrote: On Jan 19, 2012 6:24 AM Iloverio wrote: Try the The Animal Medical Center510 East 62nd StreetNew York, NY 10065(212) 838-8100info at amcny dot com (They retract email addresses if you type them in.)  I am pretty sure the vet there either pioneered or does a lot of the stents.Thank you so much for the info.  I fear that this medical center in NYC will be quite expensive and since my husband is out of work...we probably won't be able to swing it.  I also worry that any surgery would/could be dangerous for her because she's 12.  When Molly was first diagnosed they vets office did mention something about surgery and my husband piped up right away saying we "didn't want to put her through it".  They also said they probably couldn't guarantee anything after which left a bad taste in his mouth. I guess we don't agree on this subject...but I'm so worn out I leave a lot up to him because I'm not thinking clearly.  Do you mind me asking how much Rio's surgery cost?  Did you say it was an out patient procedure.  I guess I'll try and do some research on it.  Thanks so much for your time with me.  Hi Barbara, Yes the stent in any private practice is very expensive. It helps sometimes if you try to find a Veterinary School at a University that has a small animal clinic (that does laser ablation or stenting). This brings down cost because a lot of their money comes from donations and grants. I am so sorry that you are going through this. It is very wearing on your body and phsyche. I know that you want to take care of Molly the best you can. This is why I am sending you a thought.  It is not my own...but it "might" be able to help. It is a list of organizations that provide funding for pet parents that are hopeful to treat their pets but find themselves in a position that they can not. I don't know the requirements to get funding or the amount of help they can give, but it never hurts to ask. 1.Speaki ng For Spot - go and google as written - and click "financial assistance for..." I don't know where in NY you live, but all avenues probably would be worth looking into. I hope this helps....even a little.  I CARE...for Molly, you and hubby. ChicasMom, Lynn   ChicasMom Thu, 19 Jan 2012 00:00:00 GMT On Jan 19, 2012 6:24 AM Iloverio wrote: Try the The Animal Medical Center510 East 62nd StreetNew York, NY 10065(212) 838-8100info at amcny dot com (They retract email addresses if you type them in.)  I am pretty sure the vet there either pioneered or does a lot of the stents.Thank you so much for the info.  I fear that this medical center in NYC will be quite expensive and since my husband is out of work...we probably won't be able to swing it.  I also worry that any surgery would/could be dangerous for her because she's 12.  When Molly was first diagnosed they vets office did mention something about surgery and my husband piped up right away saying we "didn't want to put her through it".  They also said they probably couldn't guarantee anything after which left a bad taste in his mouth. I guess we don't agree on this subject...but I'm so worn out I leave a lot up to him because I'm not thinking clearly.  Do you mind me asking how much Rio's surgery cost?  Did you say it was an out patient procedure.  I guess I'll try and do some research on it.  Thanks so much for your time with me.   barbef Thu, 19 Jan 2012 00:00:00 GMT Try the The Animal Medical Center510 East 62nd StreetNew York, NY 10065(212) 838-8100info at amcny dot com (They retract email addresses if you type them in.)  I am pretty sure the vet there either pioneered or does a lot of the stents. Iloverio Thu, 19 Jan 2012 00:00:00 GMT Rio is 10 years old.  I consulted with 3 vets -- our regular vet, the one at the emergency clinic where I brought Rio when the blood was getting bad, and the oncologist.  All recommend the 2 antacids with Piroxicam.  Most people on this post are using antacids with Piroxicam, to protect the stomach lining.  There is a holistic vet where I live -- I tried to get in, but she is booked months in advance.  But my regular vet conferred with her, and she prescribed the herbs and mushroom drops.  I have been thinking about you all day.  I remember reading online that the stent procedure was developed by a vet in New York.  I will try to search and find it for you.  I know the surgeon who performed the procedure on Rio had training from the New York vet.  It would be good to just get an opion.  My vet said Wheatens usually live to age 14 or 15, so I think 10 is pretty young for this devestating a disease.  We live on a golf course, but it is a wetlands and wildlife preservation area, so I don't think they use harsh pesticides, but I am not sure.  I intend to find out.  Someone else who posted lives on a golf course as well.  This disease is directly traced to pesticides and environmental things like that. Just makes me sick that we are killing our planet, ourselves and our pets with all these things.  Iloverio Thu, 19 Jan 2012 00:00:00 GMT On Jan 18, 2012 5:12 PM Iloverio wrote: Sorry, I realized I had confused your dog's name with Ripley's after I hit "send."  The stent does have something to do with the size and location of the mass.  I don't have the figures offhand, but I do know that they did an ultrasound and x-rays.  In Rio's case, the stent would help keep the tumor from blocking one kidney from functioning.  The other kidney was already blocked, but dogs can function well with only one kidney.  After the stent and 3 rounds of chemo, the tumor shrunk considerably and the bleeding and frequent urination stopped as well.  The stent alone, though, also had dramatic results.  I would try to see Dr. Cerf in New Jersey -- I think it is Ridgewood Veterinary Hospital, but you can find his name in posts on this site.  His laser surgery is not curative, but combined with chemo will buy you some time.  Rio still takes Piroxicam, misoprostal and omneprostal every day, plus mushroom drops and Chinese herbs.Hi again,  Thank you for responding so quickly.  If find myself constantly checking this sight for info...yours is very helpful. Did you put Rio on those other meds on your own? The only one my vet is using is Piroxicam.  It makes you wonder who's right or wrong with this.  By the way, how old is Rio?  If you did decide to use the supplements on your own how did you figure out how much and when to give them.  As always, I would really appreciate your feedback. Thanks so much. barbef Wed, 18 Jan 2012 00:00:00 GMT Sorry, I realized I had confused your dog's name with Ripley's after I hit "send."  The stent does have something to do with the size and location of the mass.  I don't have the figures offhand, but I do know that they did an ultrasound and x-rays.  In Rio's case, the stent would help keep the tumor from blocking one kidney from functioning.  The other kidney was already blocked, but dogs can function well with only one kidney.  After the stent and 3 rounds of chemo, the tumor shrunk considerably and the bleeding and frequent urination stopped as well.  The stent alone, though, also had dramatic results.  I would try to see Dr. Cerf in New Jersey -- I think it is Ridgewood Veterinary Hospital, but you can find his name in posts on this site.  His laser surgery is not curative, but combined with chemo will buy you some time.  Rio still takes Piroxicam, misoprostal and omneprostal every day, plus mushroom drops and Chinese herbs. Iloverio Wed, 18 Jan 2012 00:00:00 GMT On Jan 18, 2012 6:50 AM Iloverio wrote: Barbara -- I have a Wheaten, too, also diagnosed in October.  Ask about a stent being inserted.  Your oncologist can recommend a veterinary clinic.  This is non-invasive and usually out-patient surgery.  It really helped my dog, Rio.  Where do you live?  I live in Colorado.  Wheatens are very special -- if you read my posts you willl know I understand just how you feel.  Wheatens are simply joyful about life, eating, playing and going for walks.  If they are not feeling good, we know it immediately.  God bless and take cae of you and Ripley. Marianne  Hi Marianne, My dog's name is Molly...I know  it gets confusing on these sights. Anyway, I live in NY and no one mentioned this stent to me.  I will ask when we go back for our blood work.  Where is your dog's mass. Maybe that has someting to do with getting a stent or not.  How are they treating your dog?  Does she still need to go out all the time to pee and is she being given any drugs.  So many questions, but its so confusing and overwhelming. Would love to hear more about how you're dealing with this horrible diagnosis. Thanks again. Molly's Mommy barbef Wed, 18 Jan 2012 00:00:00 GMT Barbara -- I have a Wheaten, too, also diagnosed in October.  Ask about a stent being inserted.  Your oncologist can recommend a veterinary clinic.  This is non-invasive and usually out-patient surgery.  It really helped my dog, Rio.  Where do you live?  I live in Colorado.  Wheatens are very special -- if you read my posts you willl know I understand just how you feel.  Wheatens are simply joyful about life, eating, playing and going for walks.  If they are not feeling good, we know it immediately.  God bless and take cae of you and Ripley. Marianne   Iloverio Wed, 18 Jan 2012 00:00:00 GMT On Jan 17, 2012 8:04 PM livininca06 wrote: Hi everyone!  My 10 year old Yorkie Ripley was diagnosed with TCC almost one year ago.  He's been on piroxicam since the beginning but we just lowered his dose because his BUN and creatine levels keep going up.  We've used/tried many of the chemo drugs.  Vinblastine was working for the last 4 months or so but our last ultrasound showed some new small tumors.  We're running out of options but just started Gemzar.  Has anyone had any experience with this drug?I am so sorry to hear about Ripley but if you've gotten through a whole year, you have a lot to be thankful for.  My sweet Molly, a 12 year old soft coated wheaten was diagnosed in October and I can't imagine she could make it to a year.  She is also on piroxicam daily with an antacid. She has to pee every 2 hours sometimes even shorter periods and dribbles even after I think she's voided everything she could.  She seems more tired lately and over the last couple of days hasn't been as excited about eating as she was.  I continue to cry and pray and wish I could wish it away, but no such luck. I haven't heard of the drugs your referring to but if you surf around this website you're bound to find someone who has.  There are so many wonderful dogs with these horrible disease. How has your Riley been during the year?  Any ups or downs...just wondering.  Anyway, good luck to you and your baby. Barbara, Molly's mom barbef Wed, 18 Jan 2012 00:00:00 GMT Hi everyone!  My 10 year old Yorkie Ripley was diagnosed with TCC almost one year ago.  He's been on piroxicam since the beginning but we just lowered his dose because his BUN and creatine levels keep going up.  We've used/tried many of the chemo drugs.  Vinblastine was working for the last 4 months or so but our last ultrasound showed some new small tumors.  We're running out of options but just started Gemzar.  Has anyone had any experience with this drug? livininca06 Tue, 17 Jan 2012 00:00:00 GMT These might be by prescription, not sure -- I got them from my vet who conferred with a holistic vet.  But here goes: Maitake Pet Formula are the mushroom drops.  The herbs are WeiQi Boosters -- Chinese herbs.  They are a mixture of Oldenlandia, Sculielaria, Angelica and a few other herbs to build the immune system.  Also there is a Plum Flower Brand mixture called EightRighteous designed for urinary tract health.  If you find a holistic vet, they will know. I only give 4 of each per day instead of wht they recommend or otherwise I feel I am popping pills in him all day.  Iloverio Mon, 16 Jan 2012 00:00:00 GMT I almost bought a St. Francis statue when I was in Jerusalem.  I have been gravitating towards St. Francis lately, and I think that is a great idea!  I'm going to do the same.   Iloverio Mon, 16 Jan 2012 00:00:00 GMT On Jan 16, 2012 1:23 AM MyPeaches wrote: Christine, Lynn and Barbara, Thanks for the info about carbs and sugar.  I didn't realize how bad that was for the cancer.  I have been hiding Peaches' pills in bites of Pumpkin Roll (UGH!) to keep her from spitting the pills out.  I actually stocked up on Pumpkin Rolls around Thanksgiving (I have 5 in my freezer) becasue it was the only thing I could hide her pills in w/o her spitting out.  She LOVES her pumpkin rolls.  Now, I find out this is feeding her cancer.  Again, UGH!  Ok, now to the store to buy meat to cook and use as treats and get rid of all the treats I have been using.  As for the Peekeeper, the owner did get back to me.  She gave me the name of another product - Tinkle Trousers, that have larger sizes.  I am going to order her one tomorrow.  As for the crying - I have done a ton of it!!!!!  Sometimes I wonder how I still have any tears left.  I have noticed how upset Peaches gets when I cry, so I try not to do it around her anymore.  They REALLY pick up on our emotions, so it is always best to be upbeat and happy around them (right, like that is easy when your heart is broken in half).  I do believe in miracles and I have been praying for over a year and a half.  Peaches has been on the prayer list at my church several dozen times.  I really thought God would heal her, but I'm not sure that is in His plans.  He is helping me get through this, though.  Praying does help me and gives me strength to get through it.  God gave her to me for a reason, and I am SO thankful for the love we have for each other.  Right now, she is laying on the floor next to me and my daughter is on the floor next to her reading her a story.  It actually looks like Peaches is enjoying the story!  Anyway, you are all in my prayers.  I am so sorry any of us has to go thru this.  We all need to remember to be thankful that we were given these special dogs.  I keep thinking of what would happen to Peaches if she had another family who didn't give her the love, support, medical attention that she needed.  Thank you God for every day I have with her!!!!Please don't feel bad about the pumpkin rolls.  In the end, I used anything and everything to get Bella to take her pills.  If that works and nothing else does, go with it.  One month before she died, she refused to take the pills (no matter what I put them in)  and I decided that she could stop.  I could tell she was getting weaker and weaker anyway.  I fed her anything and everything she felt like and that wasn't much, but I couldn't let her die of starvation. I did go with cancer friendly diet in the beginning, but sometimes you have to do what you have to.  We have enough bad feelings to deal with, not to add guilt to the mix. MomToBella Mon, 16 Jan 2012 00:00:00 GMT Yay Rio! Please tell us what mushroom drops and herbs you are using. I love that our babies probably get better food than us! lol. ! PiccoloMom Mon, 16 Jan 2012 00:00:00 GMT I put Rio's prayer in the West Wall (Wailing Wall) when I visited Israel in December.  Prayers work.  Just when we decided to stop the chemo, we had an ultrasound and found the tumor had shrunk 60 - 70%.  Now we don't know what to do.  I also give Rio 20 mushroom drops (from the holistic vet) and several herbs every day.  I use pill pockets, which he will eat.  I have even made meatballs to hide the herbs in, because he is very good about spitting them out.  Whole Foods and pet stores have high quality all-protein canned foods, and there is all-protein kibble from Ancana and others you can buy.  I use Salmon oil and fish oil tablets, too.  Not sure what is working or not.   Our grocery bills are rising (but who cares) with buying Rio skinless chicken breasts, salmon and lean ground beef.  He likes the protein and the variety, but I give him canned food sometimes, too.  I agree we are privileged to have these special creatures for as long as we do have them.  Having Rio back to his old self since the tumor has shrunk has made me realize how sick he felt before.  Now he brings out his toys, does tricks and dances on his hind legs for treats.  He had not done these things for 3 months.  Iloverio Mon, 16 Jan 2012 00:00:00 GMT Christine, Lynn and Barbara, Thanks for the info about carbs and sugar.  I didn't realize how bad that was for the cancer.  I have been hiding Peaches' pills in bites of Pumpkin Roll (UGH!) to keep her from spitting the pills out.  I actually stocked up on Pumpkin Rolls around Thanksgiving (I have 5 in my freezer) becasue it was the only thing I could hide her pills in w/o her spitting out.  She LOVES her pumpkin rolls.  Now, I find out this is feeding her cancer.  Again, UGH!  Ok, now to the store to buy meat to cook and use as treats and get rid of all the treats I have been using.  As for the Peekeeper, the owner did get back to me.  She gave me the name of another product - Tinkle Trousers, that have larger sizes.  I am going to order her one tomorrow.  As for the crying - I have done a ton of it!!!!!  Sometimes I wonder how I still have any tears left.  I have noticed how upset Peaches gets when I cry, so I try not to do it around her anymore.  They REALLY pick up on our emotions, so it is always best to be upbeat and happy around them (right, like that is easy when your heart is broken in half).  I do believe in miracles and I have been praying for over a year and a half.  Peaches has been on the prayer list at my church several dozen times.  I really thought God would heal her, but I'm not sure that is in His plans.  He is helping me get through this, though.  Praying does help me and gives me strength to get through it.  God gave her to me for a reason, and I am SO thankful for the love we have for each other.  Right now, she is laying on the floor next to me and my daughter is on the floor next to her reading her a story.  It actually looks like Peaches is enjoying the story!  Anyway, you are all in my prayers.  I am so sorry any of us has to go thru this.  We all need to remember to be thankful that we were given these special dogs.  I keep thinking of what would happen to Peaches if she had another family who didn't give her the love, support, medical attention that she needed.  Thank you God for every day I have with her!!!! MyPeaches Mon, 16 Jan 2012 00:00:00 GMT Hi Molly and Barbara, I hope I don't sound like I'm some "sage" that has it totally together and has a complete handle on things, because I certainly don't.  My husband and I are so tied to Piccolo that we don't travel at all anymore.  We stayed home for Christmas this year because I can't imagine putting Piccolo in a kennel now.  We don't go out because I feel like I want to spend every free nanosecond we have left with Piccolo.  And, like you, I come home for lunch so I can spoil her rotten.  She gets tired on walks, so we take turns carrying her in a sling-sack and it make my heart soar when she sniffs the air and "smiles" at us on her "walks".  Tomorrow is a holiday for my husband's work, but not for my company--and I find great comfort in knowing he'll be home with Piccolo.  Fortunately, our families understand and actually take the time to ask about her health.  We were not blessed with children, so they know Piccolo is my little girl.   I hear the same thing about how "you'll know when it is time" and "you'll grieve but get over it"...but I don't know HOW.  I have learned that Faith is ever evolving.  I keep telling myself to have faith in myself and faith in my connection to Piccolo to guide me.  I'm not much farther than that, but it is a step forward for me. Does this help at all? I've heard of graviola--I would like to try it, but I don't know of a reputable vendor (as sad as it is, there are unscrupulous people out there who will sell what I call "pond water).  If you find someone, please let me know. I'm in Athens, Georgia.  Geographically, pretty far from New York (my husband is vigorously nodding since he's from the village in manhattan).  Are you in NYC?  There must be a support group somewhere there.  So many dog-lovers there. In the meantime....you have us and we have you. :-) Christine PiccoloMom Mon, 16 Jan 2012 00:00:00 GMT That's a very good idea. I will be putting a holy object by Molly's bed tonight. Thanks. What state are you in?  I was wondering if you know of support groups where people can actually meet in person to talk about their situations? I'm in New York. barbef Sun, 15 Jan 2012 00:00:00 GMT I just had to tell you......I have St. Francis over Piccolo & Mallowmar's crate ( And strands of rose quartz for healing energy). :-) PiccoloMom Sun, 15 Jan 2012 00:00:00 GMT On Jan 15, 2012 10:55 PM PiccoloMom wrote: Hi Barbara, I am so sorry we are meeting this way- through a cancer forum.  This disease just plain sucks.  I hate it.  I hate how it sometimes makes me see everything negatively (I'm usually a pretty positive person).  Last year I was so distraught that I was angy at Spring.  Angry because I felt so dark and sad inside that I thought "How can there be sunshine when my world is falling apart!"  Crazy, huh?  Anger and fear were the dualing emotions that drove me to fight for Piccolo (just like Chica's Mom).  My husband says that its MY will and love that is keeping Piccolo with us.  Do you have a photo of Molly you could post as your profile picture?  She sounds adorable.  Chica's mom pretty much covered what we're doing with her nutrition.  I think you have definitely been on the right track--just cut out the simple carbs.  Tumors love sugar.  No matter how much Piccolo begs, she doesn't get chips or anything sugary (poor girl--like Chica, she has radar for the sound of cellophane bags).  Initially we tried some lower carb canned foods (Nature's Variety Instinct and the Blue Buffalo brands--give them a try---you can even buy online), however Piccolo started turning her nose up at all the flavors.  My husband had been making her eggs, chicken, steamed veggies, steak, and salmon, so I think she just preferred the special, warmed, homemade food.  We've been lucky with regards to appetite, so far.  After reading all the posts regarding piroxicam and the need for antacids, we seem to be fortunate in that respect, as well.  We give Piccolo her piroxicam (the chicken flavored liquid one) immediately prior to her eating breakfast.  She hasn't had any stomach issues (so far).  Maybe this helps?   As for breath....well....its disgusting, but Piccolo has always eaten her poop (and her sister's poop), so her breath has not always been great.  One of the reasons we have her on Baytril long term is that she at the age where Veterinarians worry about putting her under for a dental.  So far her teeth are okay, but I worry about her gums and bacteria becoming septic.  If Molly's breath is unusual, you may want to take her in for blood work--if anything, it's good to have a baseline to compare to later. My husband drove us home from the oncologist when Piccolo was diagnosed.  Piccolo was on my lap and I was sobbing and hugging her and sobbing (I hate that day-- still makes me cry).  Piccolo looked up at me and turned to put her paws on my chest and look at me with stress and concern (she whimpered at me).  I realized then that I had to reign it in when I'm with her.  It is hard to do sometimes, but we have to remember, our babies don't know they're sick but they respond to our emotions.  Its so important that we keep them comfortable and "un-stressed" as much as we can.  When humans experience stress, our immune systems don't function as well.  Same for our canine babies.   I know its hard--I go days when I'm okay and then for no reason I'll have a few days of crying.  My husband says it breaks his heart when he finds tissues under my pillow or hears me crying in the shower, but he knows I have to get it out.  And the longer we go past the projected lifespan date, the more I lull myself into thinking MY Piccolo is going to be the one who beats it.  Then we'll get a lot of blood in the urine and I'll be reminded that the tumor is active.  Such a range of emotions, when I think about it.  Anger, sadness, fear, denial....its all there.  The important thing is to keep researching and doing all you can to fight this cancer.  My heart is with you.  Courage. -Christine Hi Christine, Thank you for getting back so quickly. I guess we all spend way too much time on this sight looking for answers and support. I too have felt such anger but the sadness is the thing that is the worst.  I sometimes wonder if I'll ever stop crying. I too want to fight for my Molly but I always feel like I don't know the right thing.  I analyze every movement she makes and continue to wonder if she's okay.  The vet says dogs can be very stoic so I really don't know what's going on and that kills me.  I sometimes think I'm so selfish because I can't imagine letting her go but everyone says "you'll know" but they don't exactly tell me HOW!  In the meantime, I find we don't go out as much and i'm fortunate (lol) that my husband is out of work now and can stay home every day with Molly. I work locally so I come home at lunch too. I was wondering what the course has been for you or anyoneelse facing this?My vet has been seeing Molly every 4-6 weeks for blood work. They are watching the kidney function, but even though the numbers have gone up the vet continues to say only we can determine her quality of life.  Has anyone's dog lost weight?  At first I thought it was because she stopped eating the milkbones, but now I think it's the disease.  Has anyone heard of Graviola? I've read some interesting things about the product as well as something called es clear..an herbal liquid?  I don't know anymore, I just want to get whatever I can to make her days more pleasant.  I will try the Blue Buffalo brands and I once again appreciate all of your help.  I have a million picture of Molly but I'm not sure how to get one on the sight...all my pictures are around the house in frame. With thanks, Barbara barbef Sun, 15 Jan 2012 00:00:00 GMT Thank you Christine. We're pushing on and hoping to make it three in July. Chica will be nine in April. !!NINE!!....I thought we would never see it but she is getting some grey around her snout and some in her face. This actually brings tears to my eyes but unlike all the other times...they are tears of joy and thankfulness.  St. Francis sure loves my little creature....I pray and he helps me deliver all that I need for her. I thank him every night before I go to sleep with my little 100+ degree bedwarmer snuggled against me. Everyone and every pup....have a good week.... "Hope is the companion of power and the mother of success.  For those of us who hope strongest have, within us, the gift of MIRACLES," (Sydney Bremer).... WE have to stay strong to realize these miracles. ChicasMom, Lynn ChicasMom Sun, 15 Jan 2012 00:00:00 GMT Yay Chica! Two and a half years post-diagnosis today? That gives us such HOPE! Great energy, Lynn! PiccoloMom Sun, 15 Jan 2012 00:00:00 GMT Hi Barbara, I am so sorry we are meeting this way- through a cancer forum.  This disease just plain sucks.  I hate it.  I hate how it sometimes makes me see everything negatively (I'm usually a pretty positive person).  Last year I was so distraught that I was angy at Spring.  Angry because I felt so dark and sad inside that I thought "How can there be sunshine when my world is falling apart!"  Crazy, huh?  Anger and fear were the dualing emotions that drove me to fight for Piccolo (just like Chica's Mom).  My husband says that its MY will and love that is keeping Piccolo with us.  Do you have a photo of Molly you could post as your profile picture?  She sounds adorable.  Chica's mom pretty much covered what we're doing with her nutrition.  I think you have definitely been on the right track--just cut out the simple carbs.  Tumors love sugar.  No matter how much Piccolo begs, she doesn't get chips or anything sugary (poor girl--like Chica, she has radar for the sound of cellophane bags).  Initially we tried some lower carb canned foods (Nature's Variety Instinct and the Blue Buffalo brands--give them a try---you can even buy online), however Piccolo started turning her nose up at all the flavors.  My husband had been making her eggs, chicken, steamed veggies, steak, and salmon, so I think she just preferred the special, warmed, homemade food.  We've been lucky with regards to appetite, so far.  After reading all the posts regarding piroxicam and the need for antacids, we seem to be fortunate in that respect, as well.  We give Piccolo her piroxicam (the chicken flavored liquid one) immediately prior to her eating breakfast.  She hasn't had any stomach issues (so far).  Maybe this helps?   As for breath....well....its disgusting, but Piccolo has always eaten her poop (and her sister's poop), so her breath has not always been great.  One of the reasons we have her on Baytril long term is that she at the age where Veterinarians worry about putting her under for a dental.  So far her teeth are okay, but I worry about her gums and bacteria becoming septic.  If Molly's breath is unusual, you may want to take her in for blood work--if anything, it's good to have a baseline to compare to later. My husband drove us home from the oncologist when Piccolo was diagnosed.  Piccolo was on my lap and I was sobbing and hugging her and sobbing (I hate that day-- still makes me cry).  Piccolo looked up at me and turned to put her paws on my chest and look at me with stress and concern (she whimpered at me).  I realized then that I had to reign it in when I'm with her.  It is hard to do sometimes, but we have to remember, our babies don't know they're sick but they respond to our emotions.  Its so important that we keep them comfortable and "un-stressed" as much as we can.  When humans experience stress, our immune systems don't function as well.  Same for our canine babies.   I know its hard--I go days when I'm okay and then for no reason I'll have a few days of crying.  My husband says it breaks his heart when he finds tissues under my pillow or hears me crying in the shower, but he knows I have to get it out.  And the longer we go past the projected lifespan date, the more I lull myself into thinking MY Piccolo is going to be the one who beats it.  Then we'll get a lot of blood in the urine and I'll be reminded that the tumor is active.  Such a range of emotions, when I think about it.  Anger, sadness, fear, denial....its all there.  The important thing is to keep researching and doing all you can to fight this cancer.  My heart is with you.  Courage. -Christine  PiccoloMom Sun, 15 Jan 2012 00:00:00 GMT On Jan 15, 2012 7:08 PM ChicasMom wrote: Hi Barbara, Welcome to the wacky world of TCC (of course…I AM being facetious ). There is no welcome to this mixed up world, only a lot of heartache. I CAN say we are all trying to help each other and most of the time we succeed. There are almost as many ways of feeding our fur babies as there are cases of TCC. What works for one, does not work for another. Chica is VERY interested in eating. You can’t even open a cellophane bag or pop a food saver without her arriving at your feet in a skid, sitting there like a little soldier. We actually have to count out her next day kibbles (Blue Buffalo Mature) so we can keep her weight steady. We usually take the smallest amount to feed a dog of her size and split it up into little plastic thingies, breakfast, lunch, dinner, misoprostol, piroxicam, pepcid and any other meds that have to be given at any time. I home cook chicken breast and thighs (a little garlic powder and some shredded celery, no strings, a dash of parsley) and put them through the food chopper to give with her medications. When it is meds time….it’s party time for Chica….she loves chicken. I do the same cooking and chopping method with the salmon. Dinner is also a big time for her. This is a list of what I feed Chica. Take what you can use….hopefully others will chime in and give you other suggestions…..and incorporate others to make your own diet that Molly will love. Use the ingredients that make her happy and keep her eating and drinking. Breakfast – ground chicken w/misoprostol, and her kibbles Mid Morning – ½ tablet of Cranadin (Cranberry supplement for her bladder, RX from oncologist) I was going to start her on a cranberry supplement because she seemed to be going more often, no UTI per urinalysis and culture, I was going to use something different but oncologist reviewed the product I was going to use and it contained SILICA (no good, it CAUSES stones). Cranadin has exactly what is needed, no silica. Lunch – straight kibbles Dinner – Now this gets tricky –1 brussel sprout chopped and sprinkled with 1/8 tsp. organic turmeric (I have found that 1 is all she can take without getting gas. I guess you figured out I learned the HARD way, turmeric at Whole Foods), ¼ c green beans (I use French style, no salt), salmon, Berte’s Naturals Immune Blend, Prozyme Plus (lactose free), a good squeeze of Barleans cold pressed flax oil (brown label, Whole Foods) and 1 Solray Salmon Oil Capsule (pricked with pin and squeezed on top of her dinner, also Whole Foods), last but not least….topped with her dinner kibbles. 6 P.M. – ground chicken w/misoprosol and kibbles 7 P.M. – ground chicken w/piroxicam and kibbles  9 P.M. – ground chicken w/pepcid ac and kibbles Remember……all the kibbles for the whole day were portioned out to their little plastic thingies so I didn’t overfeed for the day. Six, seven and nine P.M. usually get 8 to 10 kibbles…seems very little but meds need some food. Well, there you have it, our day in a nutshell…day after day. Others do it differently…this works for us. Her treats consist of one or two regular kibbles or a 1/2 a biscuit of Blue Buffalo Salmon Treat. Oh…on breath…the only time I smelled something sort of….pungent, was when I was giving too much turmeric. I cut back on the turmeric and the pungent smell is gone. If Molly is still having “breath” you might want to get a kidney function test done to see what you are dealing with. Sometimes it’s just a matter of a cleaning of the teeth to get the gums healthy to clear up “breath”. Keep her drinking, if she refuses to drink, I usually save all my broth from the homemade chicken (I freeze it). I put some broth mixed with water to get Chica to drink if she slows down (at first more broth, less water and as she starts drinking, more water than broth, then stop broth. By then she is drinking straight water again. Try to stop crying….crying takes up too much of your valuable energy….use that energy to find new ways to fight this disease and make Molly more comfortable. I KNOW how hard this suggestion is…I was a bathroom/shower crier…till I got angry. I also did not want Chica to pick up on my sorrow, they are very tuned in, you know. Now I have hope in my heart and every day I get up and do the same thing that I did yesterday….fight. We have been doing this for the last 2 ½ years (on January 15, oh that’s today). They only gave Chica 6 months in July 2009, we HAD to fight (she was only 6 years 3 months). I know we’re on borrowed time…but we will make the most of the time we have and will fight every day. When she does go, I will know with every fiber of my being that I FOUGHT THE BEST FIGHT I KNEW HOW! So there, TCC, put that in your pipe and smoke it! ChicasMom, Lynn  Thanks to everyone who responded to my post.  Your advice has been very helpful.  I will use all of the advice and try to find the right combination for my precious girl.  I especially want to thank you for the advice about the milkbones and snausages...I just thought because she enjoyed them so much I could keep giving them to her. But I will find an alternate treat. I will keep all of our loves in my prayers and will continue to search this sight for support and advice. Love to all who care! barbef Sun, 15 Jan 2012 00:00:00 GMT Hi Barbara, Welcome to the wacky world of TCC (of course…I AM being facetious ). There is no welcome to this mixed up world, only a lot of heartache. I CAN say we are all trying to help each other and most of the time we succeed. There are almost as many ways of feeding our fur babies as there are cases of TCC. What works for one, does not work for another. Chica is VERY interested in eating. You can’t even open a cellophane bag or pop a food saver without her arriving at your feet in a skid, sitting there like a little soldier. We actually have to count out her next day kibbles (Blue Buffalo Mature) so we can keep her weight steady. We usually take the smallest amount to feed a dog of her size and split it up into little plastic thingies, breakfast, lunch, dinner, misoprostol, piroxicam, pepcid and any other meds that have to be given at any time. I home cook chicken breast and thighs (a little garlic powder and some shredded celery, no strings, a dash of parsley) and put them through the food chopper to give with her medications. When it is meds time….it’s party time for Chica….she loves chicken. I do the same cooking and chopping method with the salmon. Dinner is also a big time for her. This is a list of what I feed Chica. Take what you can use….hopefully others will chime in and give you other suggestions…..and incorporate others to make your own diet that Molly will love. Use the ingredients that make her happy and keep her eating and drinking. Breakfast – ground chicken w/misoprostol, and her kibbles Mid Morning – ½ tablet of Cranadin (Cranberry supplement for her bladder, RX from oncologist) I was going to start her on a cranberry supplement because she seemed to be going more often, no UTI per urinalysis and culture, I was going to use something different but oncologist reviewed the product I was going to use and it contained SILICA (no good, it CAUSES stones). Cranadin has exactly what is needed, no silica. Lunch – straight kibbles Dinner – Now this gets tricky –1 brussel sprout chopped and sprinkled with 1/8 tsp. organic turmeric (I have found that 1 is all she can take without getting gas. I guess you figured out I learned the HARD way, turmeric at Whole Foods), ¼ c green beans (I use French style, no salt), salmon, Berte’s Naturals Immune Blend, Prozyme Plus (lactose free), a good squeeze of Barleans cold pressed flax oil (brown label, Whole Foods) and 1 Solray Salmon Oil Capsule (pricked with pin and squeezed on top of her dinner, also Whole Foods), last but not least….topped with her dinner kibbles. 6 P.M. – ground chicken w/misoprosol and kibbles 7 P.M. – ground chicken w/piroxicam and kibbles  9 P.M. – ground chicken w/pepcid ac and kibbles Remember……all the kibbles for the whole day were portioned out to their little plastic thingies so I didn’t overfeed for the day. Six, seven and nine P.M. usually get 8 to 10 kibbles…seems very little but meds need some food. Well, there you have it, our day in a nutshell…day after day. Others do it differently…this works for us. Her treats consist of one or two regular kibbles or a 1/2 a biscuit of Blue Buffalo Salmon Treat. Oh…on breath…the only time I smelled something sort of….pungent, was when I was giving too much turmeric. I cut back on the turmeric and the pungent smell is gone. If Molly is still having “breath” you might want to get a kidney function test done to see what you are dealing with. Sometimes it’s just a matter of a cleaning of the teeth to get the gums healthy to clear up “breath”. Keep her drinking, if she refuses to drink, I usually save all my broth from the homemade chicken (I freeze it). I put some broth mixed with water to get Chica to drink if she slows down (at first more broth, less water and as she starts drinking, more water than broth, then stop broth. By then she is drinking straight water again. Try to stop crying….crying takes up too much of your valuable energy….use that energy to find new ways to fight this disease and make Molly more comfortable. I KNOW how hard this suggestion is…I was a bathroom/shower crier…till I got angry. I also did not want Chica to pick up on my sorrow, they are very tuned in, you know. Now I have hope in my heart and every day I get up and do the same thing that I did yesterday….fight. We have been doing this for the last 2 ½ years (on January 15, oh that’s today). They only gave Chica 6 months in July 2009, we HAD to fight (she was only 6 years 3 months). I know we’re on borrowed time…but we will make the most of the time we have and will fight every day. When she does go, I will know with every fiber of my being that I FOUGHT THE BEST FIGHT I KNEW HOW! So there, TCC, put that in your pipe and smoke it! ChicasMom, Lynn   ChicasMom Sun, 15 Jan 2012 00:00:00 GMT Hi Barbara I'm so sorry Molly has this dreaded disease. I too fed my dog whatever he wanted to eat. Carbs are bad for them because they turn to sugar and sugar feeds the cancer.  So I would stop the snausages and milk bones. They both have sugar. Eggs, beef, chicken are all fine.  I use to make my dog beef or chicken with some green beans.  Any vegetable but potatoes and carrots. They have tons of sugar. Also blue buffalo wilderness is grain free and high protein if she likes kibble. They have a wieght control recipe that I use. My dogs love it.  TJ was on Proxicam and prilosec as well.  tjsmom Sun, 15 Jan 2012 00:00:00 GMT On Jan 12, 2012 4:58 PM Chloebeaglemom wrote: Thanks Christine for responding. Yes I am working with Dr. Phillips. I still feel like I should have taken her to the university hospital to get their opinion but Chloe is a very nervous dog who is afraid of a lot of certain noises and situations. My vet recommend Dr. Phillips and I think it will be more user friendly for Chloe. She has separation anxiety and takes meds for that. Im not working now so I try not to leave her at all. She acts fine, you would not know anything was wrong except when she goes to pee. I'm worried about the effects of the chemo. What side effects did you see and what food and other nutritional things are you using? I've constantly been on the computer researching everything. I just look at her thinking how normal she seems laying here snuggling with me on the sofa. I just hate the thought of what is starting tomorrow. Have you heard of anyone using the meloxicam instead of piroxicam? She is only 8 and it just kills me to think of what we will be facing in the coming months. Any sugestions you have are greatly appreciated. Will be thanking of you and Piccolo during this time also. Thanks again, Chloe's mom, SusanThis is my response to Christine, Debbie, Lynn and Susan.  I guess I've paid the most attention to your posts because they are the most current and have hit home for me the most. This sight really does help but in another way it confuses me.  I have read so much that I don't even know where to go with this horrible disease.  The one thing I haven't been able to ascertain is what everyone is feeding their dogs.  Since Molly is still interested in eating my goal is to give her anything she wants, however, I've read that carbs feed the cancer so I have taken away anything with carbs.  She does love chicken and beef so I cook them daily and add carrots.  I haven't added any other vegetable yet.  Does anyone have any food ideas they could share.  And what about breakfast.  I've been making her eggs with some of her regular kibble (Iams healthy plus).  I sometimes add shredded cheese because she adores cheese.  I just wish there was a menu I could find to know just what's right for her.  I have noticed she turns her nose up at Milkbones (which used to be her favorite treat).  I've since replaced them with Snausages and other fun smaller dog treats.  I do know she has lost weight...and have read that the cancer does this as well.  Have any of your dogs lost any weight even while eating.  She continues to be on an antacid and piroxicam once a day.  She is just about finished with Baytril for a UTI and thanks to your posts, I am going to ask the vet about a long term course of treatment to ward off if possible further UTIs.  Do any of you find that your baby's breath smells.  Molly has an unusual smelling breath and I think I've read it has to do with the kidney function.  I am so scared and paralyzed by this nightmare.  Crying has become part of my daily and nightly routine.  It does help to know there are so many of us out there but I wish we were bonding about something pleasant and not this nightmare.  I look forward to hearing from anyone with anything they can share to help. Thanks from the bottom of my broken heart, Barbara barbef Sun, 15 Jan 2012 00:00:00 GMT Hi Peaches Mom, Have you heard back from the peekeeper maker, yet? PiccoloMom Fri, 13 Jan 2012 00:00:00 GMT Hi Diva...Sorry to here about it...   nancy2martin Fri, 13 Jan 2012 00:00:00 GMT Unfortunately, the Peekeeper only fits dogs up to 35 lbs.  Peaches is 57 lbs.  I got on their website and sent an email asking them if they would do something custom for me.  I told them I would pay anything!  MyPeaches Thu, 12 Jan 2012 00:00:00 GMT Thanks Christine for responding. Yes I am working with Dr. Phillips. I still feel like I should have taken her to the university hospital to get their opinion but Chloe is a very nervous dog who is afraid of a lot of certain noises and situations. My vet recommend Dr. Phillips and I think it will be more user friendly for Chloe. She has separation anxiety and takes meds for that. Im not working now so I try not to leave her at all. She acts fine, you would not know anything was wrong except when she goes to pee. I'm worried about the effects of the chemo. What side effects did you see and what food and other nutritional things are you using? I've constantly been on the computer researching everything. I just look at her thinking how normal she seems laying here snuggling with me on the sofa. I just hate the thought of what is starting tomorrow. Have you heard of anyone using the meloxicam instead of piroxicam? She is only 8 and it just kills me to think of what we will be facing in the coming months. Any sugestions you have are greatly appreciated. Will be thanking of you and Piccolo during this time also. Thanks again, Chloe's mom, Susan Chloebeaglemom Thu, 12 Jan 2012 00:00:00 GMT Hi Chloebeaglemom, I'm so sad to hear you had to start the new year off with this diagnosis- not that any time of the year is any better.  If you're at U of T, I'm guessing you're speaking with Jeff Phillips' group?  If so, he is a great researcher and compassionate DVM.  We've done some collaborative projects with him, and I am heartened to hear you've found him and that group. Dr. Phillips actually heard about my Piccolo through another colleague and got in touch with us about the hyperthermia (it is a l-o-n-g story, but at the time I had personal access to the device that delivered the heat through microwave technology).  Hyperthermia has been tested in human trials (it is FDA approved and there are several studies published ), so it is not unfounded technology.  Dr. Phillips guided me through the protocol of Chemotherapy and hyperthermia and we performed most of it at home (my veterinarian helped administer the Carboplatin on chemo days).  At that time we were doing heat/microwave 3x weeks and we made it through two chemo sessions.  Piccolo was also on Piroxicam as prescribed by my Vet.  After the second chemo, we decided to finish the heat/microwave portion of the protocol, but did not go for a third round of chemo.  It was just too much for Piccolo and her CBC showed she was crashing- she was 14 at the time.  We upped the baytril to ward off infection, and stopped the piroxicam for a week.  Once she recovered from the chemo (little fighter that she is), we took her back in for ultrasounds.  The tumor (in the trigone area) had not grown any, but we did not see any decrease in size either.  HOWEVER, I will say that results will vary from patient to patient.  Remember we didn't do the last chemo session, and there was an issue with the pad used to deliver the microwaves and Piccolo's small size.  Its critical that the pad is placed in the correct spot--Piccolo is very small with narrow hips, so it was difficult to get the wide pad exactly where it needed to go and hold it there for about 50min (xanax for Piccolo....and later, Mommy to get her to stay still).  This was back in April 2011, when I was told she probably only had a month or two to live.  I'll take these 9 months and whatever we have left.  Her tumor is active again, but she still shows interest in her favorite activities. So far she still barks for her food, runs into the kitchen when she hears the cutting board come out (broccoli time), and chases down the occassional bird.  We focus mainly on nutrition and continue to administer Piroxicam and baytril as prescribed by my veterinarian. It is overwhelming---sometimes I can't breathe when I think of what is coming.  This forum has helped us more than I can express.  Trust your gut- you'll know if Chloe can continue with the chemo or not.   Contact me if you want to more about what to expect if you do go with this treatment.  Good luck!  -Christine PiccoloMom Thu, 12 Jan 2012 00:00:00 GMT I have not heard of this treatment but would definately start the proxicam to see if it shrinks the tumor. My vet and several others do not believe in chemo or radiation for TCC.  The only treatment I am aware of that works is laser to actually burn away the tumor. It is very expensive, approx 8 thousand dollars and there are only a few vets in the country that do it. I used proxicam on my dog and it did reduce the tumor a bit; enough so that he wasn't peeing constantly.  My dog was bleeding and becoming anemic. It is just an awful disease. Prayers are with you. tjsmom Thu, 12 Jan 2012 00:00:00 GMT My 8 yr old beagle was diagnosed with TCC on Jan. 2 after ultra sound. She had been on antibiotics off and on for 3 months for uti. Started back in Sept. when I would try to take her on a walk, she would stop 20 times to pee. I live near the U. Of TN vet. School. I am using a dr. That was a teacher at the school. He specialized in TCC. He works at the pet emergency where we had the ultra sound done. He wants to start Friday with chemo(once every 3 weeks, with meloxicam, and a new treatment called hypothermia once a week. It sends some kind of microwave heat to the tumor to kill off the tumor cells. Has anyone heard of this or used meloxicam instead of piroxicam. He said it works as well and is cheaper. I still may insist we use piroxicam. We're going to do this for 6 weeks then another ultrsound to see if it is shrinking the tumor(in the trigone area). There has been no bleeding yet just squatting to pee a lot when she goes out which is not that often really. Overwhelmed with so many decisions to make and hoping we're doing the right thing.                Chloebeaglemom Thu, 12 Jan 2012 00:00:00 GMT Hi Debbie, It sounds like Piccolo and Peaches are on a similar routine.  You are so right....it is exhausting.  Exhausting!  Like Peaches, Piccolo has to pee constantly.  The Peekeeper really saved what was left of my sanity. Look for the website online (peekeeper.com).  It really is escape proof and the way it fits on Piccolo, she is able to poop when it is on (wonderful!--if you see in a couple of post back I write about my rookie mistake with regards to a regular doggie diaper).  Although Piccolo will never really like any diaper, I noticed she didn't just lie down when I put it on.  With the regular diaper we had to coax her to move (and most of the time she'd wriggle on her back and take it off). With the Peekeeper she was walking around like normal.  I tried that potty patch, too, and Piccolo would put her front paws on it and pee (her back legs on the ground). Yes! I know what you mean about the blood.  My Vet (who had been through this with her dog Stella), told me that this is just part of the disease.  Sometimes a lot of blood and sometimes not.  Sometimes Piccolo's pad is just completely RED, sometimes Red/brown.  Normal or not (the new "normal", anyway), it makes my heart ache. This is the only time I have been glad my hubby never let her sleep with us in our bed (he was always afraid we'd roll on her and crush her).  Her crate has always been in our bedroom so at least her bed is where it always has been (on my side of the bed, of course). Now, sometimes I lie there just listening to her breathe.  I completely understand about not wanting to put her in another room- you're right, Peaches would probably see it as punishment. And I'm like you- I just want my baby near me. I'm so happy to hear Peaches is enjoying her favorites.  That's the guideline I'm going by.  I do pretty well as long as I don't read into every little thing she does. :-) Take care and give Peaches a snuggle from us. PiccoloMom Wed, 11 Jan 2012 00:00:00 GMT Hi Lynn, It is so funny you mention the "peekeeper".  I tried the regular doggie diapers, but they didn't fit well on Piccolo's mini-dachshund body.  I love the "peekeeper"- it is one she can't get out of and the way it fits her, the opening allows her poop while its on.  I loved this especially, after making a big mistake when trying out the regular doggie diaper-I forgot about Piccolo's pooping routine (so focused on bladder issues), resulting in her pooping in the diaper (No!!!! Rookie Mistake). I love hearing that you have tried sneaking on vet med sites.  There is so much information out there that its hard to weed through it all to find the nuggets of good reporting.  I wish I had great sites to go to, but most seem to just cut and paste the same material from other sites.  I needed something less textbook and more real. Reading this entire forum has been the best source of information. All of us here are fighting for our loved ones lives and doing the best "legwork". I figure when you combine all of us, we must have the advice of veterinarians, oncologist, and nutritionists from all over the country. Not to mention the real observations we share from caring for our little ones.  I love the image of you bribing Chica with her supper dish.  It is so familiar to us, too.  That picture of Piccolo was taken on the way home from the Vet for a nail trim.  The ride there was a different story- she gave me the snub all the way there. Take care! Tell Chica she has some new friends wishing her well! PiccolosMom, Christine PiccoloMom Wed, 11 Jan 2012 00:00:00 GMT Christine, I am so sorry and I know how you feel becasue I am going thru the exact same thing right now.  My Peaches was diagnosed on 6/1/10 - a year and half ago.  Long story with all of that but finally after getting the correct diagnosis, she has been seeing the oncologist and is on Piroxicam (plus Pepcid AC) and occassionally Tramadol.  Just about 2 months ago she started peeing blood.  The oncologist did a urine culture (as opposed to a urinalisys) and determined that she does NOT have a bladder infection.  She told me the blood is just a progression of her disease.  With this blood (sometime her urine is just tinged with it and sometimes it is completely RED), I noticed that she seemed more uncomfortable than before, so I am giving her Tramadol in addition to the Piroxicam when I believe she is uncomfortable.  Also, she cannot hold her pee for more than a few hours.  I am going crazy trying to figure out how to let her out every 2-3 hours (my husband and I work full time) and am up alot in the night letting her out.  I am exhausted!  She didn't take to the potty patch and wont pee in just one area.  I bought a 6'-8' piece of patio carpet and tried to get her to pee on that - not working.  We have been leaving our downstairs door open when the temperature is above 35 degrees.  It is harder to get pee and blood out of the carpet!  I did buy doggie diapers but haven't had the courage to put them on her yet.  I don't know if this means her end is near or not.  She sleeps on our bed and I will not banish her to a room by herself.  She needs to be with me now and would think she is being punished if I tried to barricade her in just one room.  It is just very hard to accomodate all this frequent peeing, and it is exhausting.  She still loves all her favorites so I know it is not time yet.  Debbie MyPeaches Wed, 11 Jan 2012 00:00:00 GMT Hi Christine, When were you in North Carolina? I assume you were at the NC State Veterinary School Small Animal Hospital.  Judging by the states you were in....you hit many of the really good Vet teaching hospitals.  CO, NC, FL and TN are really good.  One other that you missed was TAMU.  We were just there in November and December doing a laser ablation/chemo.  It went very well. We are now home in NC finishing Chica's chemo at the vet school in NC State where she has received all the rest of her treatment for her TCC. Wow!!! Piccolo is 14!!! Chica was DXed at 6 years/3 months of age, this April she will be 9. We take it one year at a time. We are actually hoping that we can get her to 10 but I am getting ahead of myself....April is not here yet. What kind of diaper do you use?  We have been using a "Peekeeper".  Wonderful invention.  Some resourceful women in PA started making these when they needed something for a rescue they had. If you are not already using it just Google it as Peekeeper and it will come up.  You still use it with Poise or Serenity pads. There were several other diapers that other pet parents used, but I forgot what they are called.  All of them used the incontinent pads. The regular diaper was VERY hard to keep on Chica.  She's an escape artist just like Piccolo.  They think they're oh so cute when they do stuff like that...they are...but we can't let them know it. We joke that we misnamed Chica...we should have named her "damn dog" with all the cute? stuff she does. Ah......a research scientist......for an animal health company no less. Any good, informative sites that a mere pet mom can get to?  I have tried to sneak onto some vet medical sites (a lot give you a visitor pass) without success. Talk about bleary-eyed and exhausted, but I get my information none the less. When we were looking for the laser ablation at the vet schools, the oncologists were wonderful.  I would leave a message for a call and believe it or not....they ALL called back, answered any and all of my questions. Not only answered my questions but gave me their outlook on other procedures that might be used. Talk about a wealth of information. I am Chica's advocate but when I spoke with all the vet school oncologists...I felt like they were MY advocate...to help Chica. I felt like a million bucks! Well, got to go now. We are going to pick up Chica from her chemo. She snubs us in the car (just to show us she is angry with us for taking her there) but when I start rattling her supper dish...she's her old lovable self. Take care of yourself and hubby....I KNOW Piccolo gets the greatest of care form you both. ChicasMom, Lynn ChicasMom Wed, 11 Jan 2012 00:00:00 GMT