I was told by three different doctors not to have the needle biopsy done because most of the time it was inconclusive. After having the thyroid scan with iodine uptake, it was determined that the nodule was a cold nodule. I was then sent to an ENT surgeon that told me that 85% of nodules are cold ones (cold means possible cancer, hot means it is just a goiter growth and cannot be cancer) but not to worry because it had less than a 10% chance of being cancer. I had a partial thyroidectomy and a week later found out that I had follicular carcenoma so I had to have a second surgery.
The reason that all three of the doctors suggested not to have the needle biopsy is because they have seen many of times that a random selection of tissue does not provide enough or accurate information. If someone tells me that they have a cold nodule, I tell them just take the thing out!