Hi Abigail, I appreciate your circumstance. I had fallopian tube CA and they don't know much about it so treat me as an OV CA patient. I also have CA125 tests drawn every three months and know how frustrating and nerve racking it can be. I am very sensitive to the test so if mine gets even in the 70's they treat me. I have had Tamoxifen, Arimidex, Faslodex shots and Femara. It went down then up. I have had four surgeries through one incision line. Had breast cancer with a TRAM flap reconstruction, a hysterectomy, a laparoatomy then bowel surgery... so I have many adhesions. Anything in the intraperitoneal cavity, stomach and lower chest area, a yeast infection, possible inflamed lymph nodes, a bowel infection, can cause your CA125 to rise that is why they have so many false positives. I had to have 6 rounds of Carboplatin and my levels dropped like a brick, then went up on the last two treatments, and three months after my chemo it went up tl 48 from 31 normal being 0-35.... So WAIT another 3 months and if up a little WAIT again, if up significantly then another round of carboplatin. If it goes doen, great, if it tends to rise then they will add gemzar (another patient who went to Dana Farber CA institute in Boston) had this added to her treatment and her levels dropped to single digits. Hers was 15,000. Anyhow they would add that to my treatment, no hair loss, no nausea, no neuropathy..... so I am preparing myself....... Another thing you might want to investigate and by no means am I saying this is something that works for everyone, but it is all natural. It is called Asci or Asaci.... on the internet. It is 7 berries from the Amazone jungle, no water even added, a very strong antioxidant. My oncologist group uses it and even one of the docs use it... A lady with a count of 7500 had hers drop 200 points in three months... so I am trying it. BUT you want to check with your physician. As I said, it is all natural and onc nurse said it does not interfere with any medications or chemos but still check, this is very important. So, to answer your question, yes, if you have endometriosis I truly believe that it could cause your CA125 to rise, but you need to ask your doc, an gyn/onc and if you don't get an answer that satisfies you, get a second opinion. Good luck and prayers to you, Amy