Hi I am trying to help my niece. Was wondering if anyone can share what treatment they have had for signet cell ring cancer-(appendix, or even other), how long ago and how they are doing. Already had been treated with 5fu/oxyplatin/avastin, cancer came back most likely originating in ovaries. Now systemic chemo must be given again. It maybe same protocol or different-still evaluating. Any information would be so appreciated. Also has anyone also had the IP chemo pump with the systemic? Thank you so much.