We did Carbo/Taxol first and it stopped all spots (adrenal/lung/kidney) and was successful on only half of the liver (the other half grew). My husband has Metastatic Melanoma, IV.
He went on Temador afterwards, which was great for side effects yet one small lesion turned into five lesions within a period of about four months.
I will say the side effects are better on the Temador and perhaps just keep this as an option unless the T isn't working?
Demetria