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What Are Your Iggs?

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MotherWMyeloma
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Subject: What are your IGGs?
Date: 12/07/2007

Hi,

 My mom has Myeloma and her IGGs were 12,000.  She's been on revlimid/dexamethasone for 1 month and her IGGs have dropped to 6,000.  I know her IGGs are related to the Myeloma so the fact that they've decreased so dramatically is great.

 I'm wondering what a normal IGG count is and what other numbers on her Myeloma blood tests I should pay attention to.

 Any input is appreciated.

 Thanks!

Subject: RE: What are your IGGs?
Date: 12/08/2007
My mother had Igg count of 3646, which is about three times over the higher end of the normal range.  I will contact her doctor and look up all the numbers and post it here.  You should also pay attention to protein level-the normal range is 6.2-8.3-my mom had 8.8.  Her globulin was 5.2, and the normal should not exceed 3.2.  So, look for those things:  albumin, globulin, albumin-globulin ratio, protein, calcium.  Many blood tests should indicate if they detected monoclonal proteins which are red flags for myeloma.  
Subject: RE: What are your IGGs?
Date: 12/09/2007

Good Evening;

Normal IGG levels should range from 700-1600. But keep in mind, the test can NOT differentiate "normal" cells from cancer cells. Therefore, even though the numbers are high there are still some good cells included in this total number.

Also of importance is the M Spike. Which should be 0.

If both numbers are falling then the treatment is working, but the spike must come down.

Additionally, Kappa Free Light Chain (3.30-19.40) and Lambda Free Light Chain (5.71-26.30) also indicate the protein levels going on inside your body.

I have been told by my Dr. that he likes to see a gradual decline in the numbers. In his experience, a sharp decline usually results in a sharp rise once the meds are stopped.

Take care,

Kevin

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