My husband's EC was in his lungs when first diagnosed. We did radiation on the esophageal tumor with systemic chemo (cisplatin-radiosensitive so it aided esophageal radiation in tumor shrinkage, docetaxol and irenotecan) to go after the lung or any other mets. Ivor Lewis with lung resection next-lung was clean from chemo. Six months later nodule in lung again but wanted another scan to be sure, since it was at surgical site and you don't want to keep cutting someone open if not needed. 9 months after original lung resection, did another with small piece of esophageal removed and thought that was it. 2 months later nodules in both lungs. Planned three rounds of chemo, same drugs/bigger dosage. After round 1, lungs clean. After round 2, lungs clean. 3 months and 6 months later, lungs clean. Chemo was brutal but he is still here and recuperated well (other than emergency small bowel resection last week). Dr said the protocol we used had some of the best statistical results so we started there, but also said there were many other treatment options if he was drug resistant or something. Believe this particular protocol was developed and studied at Dana Farber. I researched it many months ago.