I, too, am in a study getting Avastin or a placebo, even tho I am pretty sure I am getting the real deal. However, My CA125 continues to climb. It is now 285.3. I had surgery 2/2/07 in which I had stage 3C OC, and they removed 4 large masses (1 the size of a cantoulope) and my colon. I feel great except for getting tired easily, but my numbers just keep climbing. The lowest they have been is 106. I have a CT scheduled for the 14th, and will find out more then. I had just turned 50 a few days before my OC was discovered.