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Craig, Can You Explain?

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Subject: CRAIG, CAN YOU EXPLAIN?
Date: 01/11/2008

Good Evening Craig;

I found this article doing some research and would like your opinion on its application to cancer and more specifically MM.

About RNA Interference (RNAi)

RNAi (RNA interference) is a revolution in biology, representing a breakthrough in understanding how genes are turned on and off in cells, and a completely new approach to drug discovery and development. Its discovery has been heralded as "a major scientific breakthrough that happens once every decade or so," and represents one of the most promising and rapidly advancing frontiers in biology and drug discovery today which was awarded the 2006 Nobel Prize for Physiology or Medicine. RNAi is a natural process of gene silencing that occurs in organisms ranging from plants to mammals. By harnessing the natural biological process of RNAi occurring in our cells, the creation of a major new class of medicines, known as RNAi therapeutics, is on the horizon. RNAi therapeutics target the cause of diseases by potently silencing specific messenger RNAs (mRNAs), thereby preventing disease-causing proteins from being made. RNAi therapeutics have the potential to treat disease and help patients in a fundamentally new way.

I'm at a loss to even pose any questions for you as I do not completely understand all that is written. Please bear with me as I will have some as I gain an understanding.

Take care;

Kevin

Subject: RE: CRAIG, CAN YOU EXPLAIN?
Date: 01/12/2008

I am out this weekend, but will look into this more closely when I return.

Very interesting.

Craig 

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