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Ovary Larger Than Normal

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Subject: ovary larger than normal
Date: 01/15/2008

I am concerned about my latest abdominal ultrasound results. My mother and grandmother had breast cancer before age 50 but no history of ovarian cancer in my family. I am 36 years old with 3 kids. My mother was screened from the BRCA genes but no mutations were found.

I had a trans-vaginal ultrasound done about a year ago and my largest ovary was 9.8ml with a functional cyst present. The cyst later resolved on a follow-up ultrasound. I had some abdominal pain recently so my doctor sent me for a trans-abdominal ultrasound. The pain went away but my u/s results came back that one of my ovaries was 16ml ! The radiologist did not make any comments about a cysts or anything suspicious. No follow-up was indicated in the report. My family doctor is not concerned at all. He said there is nothing to worry about because nothing suspicious was seen and he is not concerned about the size of the ovary. The only reason I even know the size is that I asked him to see the report.

I may sound crazy but shouldn't this be something to be concerned about? How can your ovary change in size without something being wrong? My doctor told me to stop worrying and move on. Should I listen to him or should I try to pursue this further? 

 

Doctor / Nurse
Doctor / Nurse
dr Steve
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Subject: RE: ovary larger than normal
Date: 01/19/2008

At your age, it is within normal range.  It is not common to measure ovarian volume across the United States, but is done by some doctors and centers.  See the abstract of a scientific article below.  

Ovaries certainly are very active and can fluctuate in the premenopausal years.  That is why there is a "mean" or "average".  There are a certain number of ovaries that will be much larger or much smaller at any given measurement. 

 However, once something starts getting measured you generally want to be sure that it does not keep going up.  Most likely , if you re-measure it,  it will probably go down again.....but if you're worried about the mean volume continuously going up, one might ask for one more measurement to make sure it is bouncing around within normal rather than going up continuously.  

If it keeps going up after another measurement, especially into the "abnormal" range, it might be prudent to get a second opinion.  

 


Ovarian Volume Related to Age





E. J. Pavlik Ph.D., P. D. DePriest M.D., H. H.
Gallion M.D., F. R. Ueland M.D., M. B. Reedy M.D., R. J. Kryscio Ph.D.
and J. R. van Nagell, Jr. M.D.1, 2





Division of Gynecologic Oncology, Department of Obstetrics and
Gynecology, and the, Department of Statistics, University of Kentucky
Medical Center, Lexington, Kentucky, 40536


Received 13 October 1999.  Available online 25 March 2002.





Abstract

Objective. The goal of this study
was to determine the relationship of ovarian volume to age, height, and
weight in women undergoing transvaginal sonography.

Methods.
Thirteen thousand nine hundred sixty-three women 25–91 years of age
undergoing annual transvaginal sonography as part of the University of
Kentucky Ovarian Cancer Screening Program were the subjects for this
investigation. Each ovary was measured in three dimensions, and ovarian
volume was calculated using the prolate ellipsoid formula (L × H × W × 0.523). Mean ovarian volume according to age was calculated for each decade of life.

Results. Data were obtained from 58,673 observations of ovarian volume. Mean ovarian volume was 6.6 ± 0.19 cm3 in women less than 30 years of age; 6.1 ± 0.06 cm3 in women 30–39; 4.8 ± 0.03 cm3 in women 40–49; 2.6 ± 0.01 cm3 in women 50–59; 2.1 ± 0.01 cm3 in women 60–69; and 1.8 ± 0.08 cm3 in women ≥70. Mean ovarian volume was 4.9 ± 0.03 cm3 in premenopausal women and 2.2 ± 0.01 cm3 in postmenopausal women (P
< 0.001). The use of exogenous estrogens was associated with a
significant reduction in ovarian volume in women 40–59 years of age,
but not in women ≥ 60. Ovarian volume was unrelated to patient weight
but was greater in tall women (>68 in.) than in short women (<58
in.).

Conclusion. There is a statistically significant
decrease in ovarian volume with each decade of life from age 30 to age
70. Mean ovarian volume in premenopausal women is significantly greater
than that in postmenopausal women. The upper limit of normal for
ovarian volume is 20 cm3 in premenopausal women and 10 cm3 in postmenopausal women.


 

Regards,

Dr V

www.gyncancerdoctor.com  

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