I am affiliated with a company that has just introduced a laboratory
test
to identify the tissue of origin for metastatic cancers. In November
2007, a team of pathologists from three cancer centers presented a
poster at the Association of Molecular Pathologist meeting that showed
the test successfully identified the tissue of origin for 8 out of 10
previously diagnosed as CUP. (It also reports the results of a large
clinical validation study performed on more than 470 specimens). A copy of the poster is at:
http://www.pathworkdx.com/news/AMPAbstract5.pdf
Although
I am not an MD, my life-work is in advancing the science of cancer
diagnosis - bringing new genomic technologies into the clinical
laboratory. I
thought this might be useful new information for this discussion.
Warm regards, GGA