Hi,
I just saw your post,and since no one has answered I will try to give you as much info as I can. I'm currently on Topo for my second recurrence of OVCA. I have it given 1 time a week for 3 weeks then I'm off the fourth week. This is a new way to have this chemo..it is usually 5 straight days,every three weeks. My Onc said with the way I have it I'm actually getting more of the chemo,plus there has been recent testing that it is just as good as the 5 day route. That being said. I have had very little side effects so far. I just started my 1st treatment in my 3rd round. My ca-125 has now dropped into the normal range. I have had some nausea,headaches and dizziness..all of it treatable with tylenol or compazine. I have a friend who is also on the 5 straight day of Topo,and her side effects are severe..to the point where they have stopped all treatment. Good luck!! I hope this chemo will put you back into remission...~~~Joanne