I am sorry for your father that the cancer has returned. My advice is to seek out alternate opinions to ensure that his treatment is agreed upon by other oncologists.
My spouse (43 years old) was diagnosed with Stage IV in March of 07. She was on ECF which is Epirubicin, Cisplatin, and 5FU (delivered via a pump 24/7) for 8 rounds (3 weeks each). The original two tumors (one in her stomach at the junction to the esophagus and one in her liver both about 1-2 cm) disappeared and in August of 07 she was classified as in remission. The opinions we received at that time differed: our oncologist wanted to operate but two others wanted her to remain on chemo for a year post her remission classification. We decided on continuing chemo treatments with the hopes that it would kill any micro cancer cells floating around. In September we changed from ECF to Xeloda and Oxaliplatin as her chemo drugs. She remains on those two drugs as of today and will hopefully end active treatment in March of this year.
My concern is that the only drug you mention is 5FU. There are many more choices out there and your oncologist should be recommending alternates and/or additional drugs for his treatment (in my limited and non-clinical opinion). Please seek out alternate opinions from cancer centers that specialize in treatment. Please also include your fathers age as this, at times, will play a factor in the treatment process.
Has anyone suggested that he have any of the tumor sites surgical removed. The concern I have with my wife is what to do now. No cancer that we can see and a year of chemo treatments. Whats next?
Hope he feels better. For mouth sores there are special mouthwashes and toothpaste available that will help some. Ask your oncologist and research, research, research. I have found that WE are the ones that have to do a majority of the directing when it comes to care and WE have to be prepared with alternates that WE can inquire about.
God Bless and Keep the Faith.
Steve Barrett
Hartford, CT