Average Rating:Rating
Rate this Discussion: rate!

Autologous Stem Cell Transplant

Switch to Single View
Records 1-4 of 4
Caregiver
Caregiver
TouchedbyaTurtle
Recommend this Message
Subject: Autologous Stem Cell Transplant
Date: 02/26/2008
My brother (33) was diagnosed with AML over xmas. He finished round 1 of chemo and is now in remission. There is disagreement between his doctor and another doctor at UCSF over how he should continue with his treatment.

His doctor wants to do the normal 4-round consolidation therapy. Another doctor at UCSF suggests getting an Autologous Stem Cell Transplant. Is anyone familiar with this, personally?

Any information is helpful. Thank you!
Doctor / Nurse
Doctor / Nurse
Oncrx
Recommend this Message
Subject: RE: Autologous Stem Cell Transplant
Date: 02/26/2008
good question.  I think it depends on a couple things.  One is if he has a good match for a donor.  With a poor match its not worth the side effects of the transplant.  Another depends upon his cytogenetics.  In patients with the 8:21 translocation their outcome is pretty good with chemo so generally SCT are held until relapse or second remission.  In cases of poor cytogenetics (deletions) a SCT may be in order at first remission as these patients are more likely to relapse.
Caregiver
Caregiver
TouchedbyaTurtle
Recommend this Message
Subject: RE: Autologous Stem Cell Transplant
Date: 02/26/2008

Thank you for your response. 

 Autologous Stem Cell Transplant is a new procedure where they use the patient's own stem cells, rather than those of a donor.  So there wouldn't be any matching problems. 

 However, the treatment is controversial for patients who respond to chemo.  Why take the higher risk of a stem cell transplant when patient responds to chemo?  The advantage of the Autologous Transplant is that, if succesful, it has higher chances of long-term survival and lower chances of remission. 

 As far as I know only UCSF does this operation, which is a reason for worry.  All other major treatment centers recommend continuing with chemo, but the doctors at UCSF insist that my brother receive a transplant. 

Doctor / Nurse
Doctor / Nurse
Oncrx
Recommend this Message
Subject: RE: Autologous Stem Cell Transplant
Date: 02/26/2008
does he not have a good donor match?  The allogeneic transplants have  better survival numbers than the autologous.  More problems with graft vs host ,but better survival.  Still it mostly depends on his cytogenetics.  Do you have any of that info?
Records 1-4 of 4
Switch to Single View
close




Sending...
Required Fields All fields are required.
close
User is No longer Ignored
Show messages from this user
close
Report Abuse
Anonymous Note to Administrator:

Reporting
Latest Messages Show More
RE: Hair regrowth Posted by Cindy D. on 07/23 04:50:55 PM
TG101348 Posted by Terrilynn on 07/23 04:31:58 PM
RE: I dont know what to d Posted by liz111 on 07/23 04:30:08 PM
RE: Temodar & Zofran - do Posted by TaylorsMoms on 07/23 04:21:36 PM
RE: So Scared. Posted by WhatToDo? on 07/23 04:16:27 PM
For those of you having d Posted by skylog on 07/23 04:15:37 PM
RE: `Medicare not coverin Posted by Geri28 on 07/23 04:15:15 PM
RE: psa levels Posted by Skittlebug on 07/23 04:04:07 PM
RE: Tumors Shrinking Posted by CurlyQ on 07/23 03:45:03 PM
Insurance coverage for HI Posted by rsfly on 07/23 03:33:57 PM
RE: TCC Posted by Sue in SD on 07/23 03:29:04 PM
Prostate Cancer - 3D Medical Animation