Hi Chris,
You are a very dedicated son (with an understanding wife :) to put your life on hold to care for your parents. How are your children adjusting to the move? (You were living 2 hours away, right?)
Just sent you a private message before I read this one. My dad is on irinotecan and cisplatin. After 4 treatments his tumor shrank from 5 to 4 cm. I do know that the amount was cut in half after his first treatment because he was so sick.
I have read many stories over the last few months and it seems that reactions, side effects, etc. to treatment are very individualized. What works for some may not work for others and vice versa. DO NOT GIVE UP-there are many drugs and combinations that the drs. can try.
Praying for you all