My mom was diagnosed with Stage 4 NSCLC in Sept. of 07. She also had tumors in the brain. She was given Radiation for the brain tumor and those shrunk and still seem to be to shrinking. To the point where the tumors are barely visible on the MRI. After Radiation on her brain she was given IV Chomo - Taxitol. I believe. After 2 rounds the tumor had shrunk about 30% and after 4 rounds it only shrunk a small amount. They decided not to go any further with the chemo because of neuropathy in her hands and feet. Yesterday we went back to check on the lung tumor. We were told not only had it grown but that she now had tumors in her liver. It has been recommended that she start a new oral chemo that is in phase 2 of clinical trials. The drug is called Pazopanib. My mom is pretty symptom free considering she has cancer. The only symptom she has right now is the Neuropathy. Here's are the questions. How bad are the side effects of this treatment? How will quality of life be effected by continuing treatment? Would it be better just to let the disease progress? I have always heard once it's in the liver it's just a matter of time....