Clinical Trials For Gbm

Hi All,

My son, 13, was diagnosed with GBM in May. He had radiation therapy, was on temodar and last on Avastin/CPT11. There was significant regression of tumor during the last 7 mos. Our last MRI showed new progression. As a last resort, we are offered the 5-drug regimen from Dana Farber in Boston(Phase 2 trial), or  Enzastaurin or LY Compound  (Phase2) at Washington,DC. Does anyone have any knowledge regarding these trials? Can anyone throw us a lifeline? What about the scorpion venom from Mexico someone mentioned?

Thank you so much,

Shevy

Shevy

I wish I had some information I could share with you.  This disease is so difficult, but when it is visited upon children & their families it is beyond comprehension.  I have been riding this rollercoaster with my husband since last January & that is bad enough.  I pray the drugs you mentioned are the miracle we are all waiting for.  My best to you.

Jackiekay

You could try looking into a drug called Celingitide manufactured by Merck.  It's entering final stages of trials and apparently is showing promising results for recurrent GBM.

I know of a Dr Helen Wheeler at North Sydney hospital who is currently using  it with patients.  It seems many of the clinical trials have been conducted in Europe. 

hi there

my mum is about to start cilengitde next week with Dr Helen Wheeler.

I will keep you posted on how she goes with this.

Also if any one has any good results please let me know. Oh what side effects can we expect - if any (mum had none from avastin)

Cheers

Gilda