Vomitting Husband/Avastin/Stg IV multiple liver mets - feeling helpless

Daisychain ~ I forgot to ask what "zeolite" is?

Mike, thanks for the info...i asked the oncologist today about the Davant and he said he wouldn't use anything that isn't out of clinical trails.  Help!!!! 

 

 

 

Studies Point To Benefits Of Personalized Chemotherapy Dose Management In Colorectal Cancer

yes, I did see this immediately and did convey it to our Oncologist.  I will printe or email to him and ask him to perform this.  thank you....up all night tonight, kinda don't want to sleep tonight.  Thanks again.

So sorry you and your husband have to go through this.  I know it is shocking when it happens so fast.  My dad did good for 18 months and then all of a sudden went down overnight.  We where in denial and then we had to except it.  We where with him all the time and supported him and the number one thing is to make sure they are comfortable.  Once the Dr told us about hospice we didnt try to force him to eat because we realized at this point he couldnt eat it was the disease taken over.  The reason im telling you this is because if I had to do it all over again with my dad I would of done it diferently.  My mom didnt give him his pain meds every 4 hours because it knocked him out and she wanted to be with him but that was not good for him because I beleive he suffered more pain then he should of.  Its important you give pain meds every 4 hours so they dont have break through pain.  I would definately tell your kids because they are going to want to spend as much time as possible with him at this point.  If you ever want to talk please feel free to email me on this site.  Mindy

 

On 5/16/2008 mardilove wrote:

Mike, thanks for the info...i asked the oncologist today about the Davant and he said he wouldn't use anything that isn't out of clinical trails.  Help!!!! 
The doctor said he thought my husband won't be here much past another month. Scared silly!!!!

 

 

 

 

I have to tell you that logic is crazy not to use a drug that hasn't finished trials.  The doctor just scared the daylights out of you and said your husband has a month to live and won't try anything.  Not my kind of oncologist.  Are you seriously telling me he won't even research it?  I think he is just lazy and doesn't want to do the paperwork for a compassionate use. 

If he were to call the company up they would definately be willing to give it a shot.  The problem is clearly your oncologist.  I'm sorry.  I know what I would do if I were you and its not listening to the oncologist.

Let me just explain to you a little more about DAVANAT.  It's a SUGAR designed to wrap around the chemo.  The cancer cells have a Galectin-1 receptor that is overexpressed on the cell surface that DAVANAT likes to bind with.  Since the chemo piggy backs on the DAVANAT and the DAVANAT binds with the Galectin-1 the chemo gets into the cancer cell and destroys it.  DAVANAT is mixed with 5FU - a chemo drug that has been around 30 years.

DAVANAT by itself doesn't do anything.  If you or I took DAVANAT right now -what would happen - absolutely nothing not even a sugar high.  When you mix it with Chemo it binds with it and becomes a targetting agent.  It shouldn't even be classified as a drug but because it goes into your arm that what it is.  It is called an excipient. 

 I'm rambling - perhaps you should just call me and I will explain.  I will do what I can to help but that's not going to be easy with a grumpy oncologist.  Just so you know - I got a compassionate use for a friend in 28 days.  So there is hope.  There are ways to get it faster but you need a freindly doctor. 

Mike

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Are you a doctor Mike?  What is your background?  Many of us might need davanat in the future and it would be helpfull if you share you specific experiences.  I would also recommend that you  back off on the Oncs.  You don't have the info and case history that they have.

Wondering how to convince our oncologist to run the toxic test by blood plasma?  I asked him but he said they did the BSA.  Of course he does want to convince me as he is probably assured that this is the best measure.  At this point, I am not willing to miss checking one thing.

Any suggestions?  Any help would be appreciated!

 

 

Tell him you want the toxic test and if he does not agree, ask him why.

 

Greetings to all who responded to my messages and provided hope.  My Husband left my arms on June 6th at 7:36am.  I am still in shock and really can't believe he isn't here any longer.  Because of issues with his family...lack of/and deliberate absence of support, my complete astonishment at no condolences, sympathy or support during his leaving ceremony (I can't say the "f" word) left me so bewildered I concentrated on that for almost three weeks after his passing.  I resolved that issue by just praying for them everytime I think about their lack of compassion.  A week ago it hit me full in the face that my loving husband of 28 years is not here.  I honestly don't know how I am going to make it through this, or even if I want to. 

My message to all who are fighting this nasty beast, concentrate on you and your loved one.  Don't give anyone a minute of time, spend it with your loved one.  I supported his family to even creating a web site for them to be aware of what was happening with my husband, and because I wasn't what they wanted me to be, I have been compltely ignored and talked about in the worst way.  Several letters of what a selfish person I was (because my husband didn't want to see his family) and very bad things said about me..

No I have to pray for them, since I have thought of them again instead of my Husband.  My sweet Husband who I will miss more than I can ever say.  I start grief counseling tomorrow and pray it will help me find peace and how to place my Husband in an honored place in my heart that will allow me to get on with life. 

Honestly, I still can't believe he isn't here and I miss him more than life itself.

Be good, thank you and I hope all of you are able to make it through this.

Thanks for support for my sweet Husband.

Marcy