I have had essential thrombocytosis for eight years , i could not take hydrea, lowered by white counts too low, take agrylin now and only once weekly, i weaned myself down slowly and counts are always under 400,000 now, did have pe same time and take coumadin daily, i truely have a second lease on life and can live a normal lifespan my specialist tells me. Its all working fine for me now eight years, i really dont even pay much attention the labwork unless its off which it hasnt been. Have a twin, she doesnt have it. My fiance is fighting throat cancer right now, thats becoming a real emotional strain on me., i feel like i do everything for him, no help from his family. Hhe will soon be done radiation hopefully our lives will return to normal, im not sure, emotionally i feel very different and dont know why. It has been a burden along with working. He also just lost his job, family leave time used up. Hope i have ruined this relationship.