FOLFOX is made of
Leucovorin - 5FU - Oxyplatin
The thing that is wrong with this therapy as any therapy is the side effects. Your going to get "sick and tired" The reason for this is that the chemo kills good and bad cells indiscriminantly. The good news is that there is a targetted therapy colon cancer trial. Its basically the same stuff with a twist. They add a drug, if you can call it that - DAVANAT to 5FU, Lecovorin and AVASTIN. The DAVANAT latches on to the 5FU and transports it only to cancer cells. Because it only goes to cancer cells you won't get side effects.
I have a friend that was way worse off get compassionate use of DAVANAT and her turnaround is amazing. She went from being doped up and bedridden from the bone metastis to shopping and driving in 6 weeks. The jury is still out on what happened. PET scan is due for first week of June
I don't know if you realize but this DAVANAT targetted therapy has been in clinical trials for colon cancer for 3 years. See if you can get into the trial. Go to clinicaltrials.gov and type in key word DAVANAT. I can tell you first hand that DAVANAT added to the mix targets the chemo and eliminates any side effects. This isn't just my observation - look at the clinical trial results.
Hang in there and we hope to hear some good news in the coming weeks.
Mike