This, & the "Sutent is effective" thread, should be combined, & everyone on Sutent should track them & update their experience for the benefit of the practioners, patients & caregivers! After 2 cycles of 50mg/day, the CT showed the lesions on my wife's lungs & kidney had diminished by nearly 1/3d. B/c of side effects, her dosage has been reduced to 37.5mg/day, she is now on her holiday & will have her next CT in August after her 4th round. Prayers work, & the medicine helps, too! Pax.