Low grade glioma in the left frontal lobe can that be cured.....?????

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Low grade glioma in the left frontal lobe can that be cured.....?????

by sugandha on Thu Nov 06, 2008 12:00 AM

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My uncle aged 42 has been diagonsed with Low grade glioma in the left frontal lobe today(date: nov 6th 2008). my infomation is vague on this topic and so is every1 around me..i hav scaned the net and i kw wats low grade glioma and wats the diff ways the level of glioma can be detected by grade..location and type of cell..

now my basic query is can the LGG in the left frontal lobe be cured since the MIA report only says left and I have read that it can be transfered or elongated to the right also (to quote "my infomation is still not complete as i need ugrent help and do not have the time to scan all the web pages my family and i have to up and down to the hospital)

I want to kw if this can be cured(further this is all the report says unlike the net that states the various types of gliomas..) and if yes how...?

can my uncle be saved..??if yes how??

wat will be his average life expectancy after this surgury of wat ever the treatment is???

he is a brave man with high potential and will power..bt of recent he was doing irregular activities like.....if he was laughing he continued non stop...if he said a word he repeated it infinitely..if he was eating his eating had no limit..he was consistently shown to the doctor in the last 5days and the report this evening reveals this as i have told u..

plz help....ur my last hope...the doctors keep us in dark..im the elder child after my uncle's son who is with his father in the hospital..this is a common occurance of misleading the pateints family in india...plz be precise and quick....

thank you

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by mbg53 on Thu Nov 06, 2008 12:00 AM

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On 11/6/2008 sugandha wrote:

My uncle aged 42 has been diagonsed with Low grade glioma in the left frontal lobe today(date: nov 6th 2008). my infomation is vague on this topic and so is every1 around me..i hav scaned the net and i kw wats low grade glioma and wats the diff ways the level of glioma can be detected by grade..location and type of cell..

now my basic query is can the LGG in the left frontal lobe be cured since the MIA report only says left and I have read that it can be transfered or elongated to the right also (to quote "my infomation is still not complete as i need ugrent help and do not have the time to scan all the web pages my family and i have to up and down to the hospital)

I want to kw if this can be cured(further this is all the report says unlike the net that states the various types of gliomas..) and if yes how...?

can my uncle be saved..??if yes how??

wat will be his average life expectancy after this surgury of wat ever the treatment is???

he is a brave man with high potential and will power..bt of recent he was doing irregular activities like.....if he was laughing he continued non stop...if he said a word he repeated it infinitely..if he was eating his eating had no limit..he was consistently shown to the doctor in the last 5days and the report this evening reveals this as i have told u..

plz help....ur my last hope...the doctors keep us in dark..im the elder child after my uncle's son who is with his father in the hospital..this is a common occurance of misleading the pateints family in india...plz be precise and quick....

thank you

Sorry to hear of your troubles. I'm no doctor, but I've read that low grade gliomas are treated (here in the USA) pretty much the same way high grade ones are, at least initially. Surgery(if viable), radiation with concurrent oral chemo in the form of Temodar, and then maintenance doses of temodar if they choose to be aggressive.
As far as a 'cure', I guess it depends on your definition of cure. Many gliomas can be put into remission for many, many years. The issue is that they tend to return at some point, and when they do they have a more aggressive makeup. Here we are monitored regularly to look for recurrence.
Again, not a doc, bu I hope the info was helpful.

 

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by amberrn3 on Wed Nov 12, 2008 12:00 AM

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On 11/6/2008 sugandha wrote:

My uncle aged 42 has been diagonsed with Low grade glioma in the left frontal lobe today(date: nov 6th 2008). my infomation is vague on this topic and so is every1 around me..i hav scaned the net and i kw wats low grade glioma and wats the diff ways the level of glioma can be detected by grade..location and type of cell..

now my basic query is can the LGG in the left frontal lobe be cured since the MIA report only says left and I have read that it can be transfered or elongated to the right also (to quote "my infomation is still not complete as i need ugrent help and do not have the time to scan all the web pages my family and i have to up and down to the hospital)

I want to kw if this can be cured(further this is all the report says unlike the net that states the various types of gliomas..) and if yes how...?

can my uncle be saved..??if yes how??

wat will be his average life expectancy after this surgury of wat ever the treatment is???

he is a brave man with high potential and will power..bt of recent he was doing irregular activities like.....if he was laughing he continued non stop...if he said a word he repeated it infinitely..if he was eating his eating had no limit..he was consistently shown to the doctor in the last 5days and the report this evening reveals this as i have told u..

plz help....ur my last hope...the doctors keep us in dark..im the elder child after my uncle's son who is with his father in the hospital..this is a common occurance of misleading the pateints family in india...plz be precise and quick....

thank you


Sorry to hear about your Uncle. I too have LGG stage 2 in the left lobe. dx. 4/2008 at 30 years of age.I have had surgery and the doctors estimate my life expectancy to be 9-10 years. However, there is no cure for oligodendrogliomas however, there is hope to have a long life expectancy up to 20 years or more, so I have read in research. It just depends on location, how fast it grows, other health problems. Generally they do not start chemo or radiation until the glioma becomes grade 3-4, with grade 2 they usually do the surgery try te resect out as much as they can, then watch and wait with MRI's every 3-6 months. If you would like to talk or have more questions I would like to help the best I can

Amber 

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by george2242 on Tue Mar 09, 2010 08:10 PM

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my wife has just been diagnosed with glioma on her right

side of her head.  its a stage 2 tumor and it is cancer. i am trying to get some info on her prognosis. its all new to us.

i was wondering if someone else diagnosed with the same problem could share some info with me.

george c.

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by george2242 on Tue Mar 09, 2010 08:12 PM

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my wife has just been diagnosed with glioma on her right

side of her heads.  its a stage 2 tumor and it is cancer. i am trying to get some info on her prognosis. its all new to us.

i was wondering if someone else diagnosed with the same problem could share some info with me.

george c.

ps

she had surgery and couldnt get all the tumor

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by Sherylrjr on Wed Mar 10, 2010 01:02 AM

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You first must understand that any grade of brain cancer is not curable. Survivors is the term you will hear moving forward. With what your uncle has is slow growing. There are 20 year survivors. Brain cancer affects each person differently, but has similarities.  

Treatment is usually a standard protocol of surgery if possible, radiation and chemo.

Hope this helps!

Sheryl

Son 34 dx Mar 08 AA 

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by MsRoxy on Wed Mar 10, 2010 03:47 AM

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hey girl!  long time no talk.  yep she is right about the "cure" notion only i just, yep an hour ago, into an old friend who said her sister had one in the frontal lobe, they did the surgery and she is 13 years surviving.  HALELUJAH!

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by mommamin on Tue Apr 20, 2010 10:45 PM

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Hi:

My husband has been diagnosed with a low-grade tumor as well.  Unfortunately, his is quite large and in the left temporal/parietal lobe, so they cannot operate or even partially remove the tumor.  What I advise below is based on my discussions with the Oncologist, the Neurosurgeon and my own interpretation of the medical journals I have since reviewed. However, please note that I am not a trained professional. 

I do understand what you are going through, as it took a lot of questions from us, before we could get the information out of the doctors.  I had to do my own research and then ask the doctors point blank questions so we could understand treatment options and the actual prognosis. 

If your uncle has a low grade glioma, it is cancerous, however it is slow-growing with smooth edges.  It does not have the tentacles of the more malignant grade 3 or 4 cancers (which are also very fast growing).  Low-grade (LGG) is good, and has a better prognosis. 

Depending on the location and the size of the tumor, it may be possible for the surgeon to completely remove it.  This would provide the best outcome, sometimes this is followed by chemo and radiation to ensure there is no recurrence. 

However, sometimes it is not possible to remove the entire tumor, so they may remove a portion of it, to alleviate pressure and reduce swelling. 

Regardless of whether surgery is possible or not, they will normally start the patient on Dexamethasone (Decradon) to reduce swelling in the brain, as well as Dilantin to stop seizures.  Once your uncle begins taking the medications, you should see a big change in him for the better.

Only the Doctor can determine if he is operable or not.  However, if he is, it is best to do so quickly.  Surgeries are more successful when the tumor is still low grade.

If surgery is not an option, the standard approach is for the patient to receive the medications I mentioned above, but then they are monitored periodically (given MRI's) to check for tumor growth.  If/when the tumor becomes malignant, the dr will normally use chemotherapy and/or radiation to shrink the tumor.   

Your uncle will most likely at some point get a biopsy (most doctors will want this before they even entertain giving chemo treatments), which will take a small section from the tumor that they can test to determine what type of glioma he has (ie. astrocytoma, ogliodendroglioma, mixed glioma, etc.).  When they know what type of glioma he has, they can make a better guess as to his life expectancy. There is such a wide range in survival statistics, that most doctors will not comment on them.

On average, median stats are 5 - 12 years, depending on the size, treatment, and type of tumor.  Docs would not give us a number, but this is what I found in case studies.  Those that had surgery, chemo and radiation had the best chance for longer survival.  People who received the "watch and wait" treatment, tended to be on the lower end of the scale.

I sincerely hope that your uncle is okay, and that he is a great candidate for surgery.  Good luck!

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by george2242 on Tue Apr 20, 2010 11:13 PM

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hi,

i am not sure if it makes any difference but the person in question is my wife and the tumor is on the right side not the left side. i also know now that the tumor could not be removed , only had a biopsy. she is doing 30 treatments of radiation. i still would like to know the prognosis giving this info. i greatly appreciate the info you have for me. your reply to this would be appreciated.

Regards

George Crant (husband)

 

RE: Low grade glioma in the left frontal lobe can that be cured.....?????

by Lorre_G on Wed Apr 21, 2010 01:51 PM

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The treatment for low-grade gliomas (grades 1 and 2) is perhaps even more controversial than the treatment for high-grade gliomas. This is partly because these tumors may grow very slowly or not at all. Thus, the benefit of any therapeutic intervention may require years rather than months to determine. Treatment for low-grade gliomas can similar to treatment for high-grade gliomas.  The best chance to provide treatment with intent to cure is before the tumor grows and before it has a chance to evolve into a high-grade tumor.

The initial treatment for low-grade tumors is nearly always surgery. The extent of surgery depends on the size and location of the tumor. Whenever it is possible to remove all the tumor that can be visualized on MRI scan, that would be the recommendation. Complete surgical removal of a low-grade tumor can be curative without further treatment. Most low-grade tumors, however, cannot be removed completely. In this situation, the surgery will not be curative, and would be more conservative. Sometimes only biopsy is possible to make a diagnosis. Other patients will undergo partial removal if it can be achieved safely, and enough can be removed to improve the ultimate outcome.

Once a diagnosis has been established by surgery, the recommendation is made for further treatment or careful follow-up without treatment. In our facility we usually recommend treatment for patients with low-grade tumors who do not have complete surgical removal in order to prevent recurrence and reduce the likelihood of transformation to a high-grade tumor. Since results of radiation therapy alone are unclear, we prefer an approach of initial chemotherapy. Once the response and tolerance of chemotherapy has been assessed (approximately 6 months), we decide whether to add radiation therapy. Sometimes it is possible to delay or avoid radiation therapy, while in most cases, radiation is recommended either during or at the conclusion of chemotherapy.

I want to be very clear that this is the way we treat low grade tumors at our clinic in Colorado.  This may not be the course your particular doctor will follow. 

Lorre G.

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