My brother had IV interfon-alpha July 2005, IV 3 hours a day for 5 weeks, 3 shots of 20 parts per million 3 times a week, unfortunately cancer has spread and are going to try other treatments. Side effects are unpleasant for everyone to endured. He will sleep literally for hours, loss of appetitie, may lose 10-20 lbs. Fever, chills, nausea,Watch for Dehydration!!! He managed miraculously to work and helped him mentally, would get home from work go to sleep at 5pm and not wake up until next maorning. Be patient and stay strong, good luck