In March of 2004, I was diagnosed with ovarian cancer. After surgery, 6 months of aggressive chemotherapy, and a second look surgery, I was told that I was in remission. I had check-ups every 3 months, which included an internal exam and a CA125 blood test. For over a year, I was fine. Then on October 15,2005, I had a seizure and I learned that my ovarian cancer had formed a small tumor in my brain. I had to have brain surgery to remove the tumor. My surgeon left a very small spot in my brain because he felt it was too risky to try to remove it and because, he felt that it could be destroyed by steriotactic radiation. I had the radiation and I will learn the results in a few weeks. Presently, I am undergoing chemotherapy. My oncologist/gynecologist at Mass General Hospital has put me on carboplatin and topotecean. He chose topotecean because it is the only chemo that crosses into the brain. There are no clinical trials for me. Does anyone know of anyone who has gone through what I am experiencing or do you have any suggestion? Thank you in advance. God Bless. Fran