Avastin And Gbm

I have heard some promising reports on the affects of Avastin/BCNU (and other chemos)used against GBM . Anyone out there using and combinations of Avastin. My father was diagnosed with GBM Grade IV in August and has completed his resection and first round of radiation / Temodar. He had a good AGT test and Duke put him on Temodar for 2 more months. Avastin will be an option after the 2 months are up and I wanted to get a sense of how that is working for others.

My wife ws diagnosed with GBM IV in August of 2004. Radiation and Temodar were not effective. She tried several therapies which did not work or worked for a short time. Duke started her on Avastin and CPT 11 in June 2005. It also worked for about 3 months.

She passed away in October of 2005, 15 months after the diagnosis. Everyone's experience is different.

I wish you and your father well.

I am also interested in info. on Advastin and BCNU for treatment of GBM stage 4.  My father has undergone 2 resections in 3 years.  After the first surgery he used Temador and Radiation for 1 year, no reoccurance for 8 months after treamtent ended.  He had his 2nd resection in may 2006.  Was put on BCNU and Phlimide, after 2 months 2 tumors were seen on MRI.  He was then put on the combimation of Avastin and CPT11 for the past  4 months, shrinkage of tumors occured on the first MRI (2 months of treatment) then last MRI showed tumor growth of app. 1 cm. Now they are going to try Avastin and BCNU with a new MRI to be done next month.  Does anyone have any info on the combination of BCNU and Avastin??  Would love to hear from you.