Avastin and Gbm

4 Posts | Page(s): 1 

Avastin and Gbm

by Cfish on Tue Dec 06, 2005 12:00 AM

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I have heard some promising reports on the affects of Avastin/BCNU (and other chemos)used against GBM . Anyone out there using and combinations of Avastin. My father was diagnosed with GBM Grade IV in August and has completed his resection and first round of radiation / Temodar. He had a good AGT test and Duke put him on Temodar for 2 more months. Avastin will be an option after the 2 months are up and I wanted to get a sense of how that is working for others.

Gbm

by Caregiverinnc on Wed Dec 21, 2005 12:00 AM

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My wife ws diagnosed with GBM IV in August of 2004. Radiation and Temodar were not effective. She tried several therapies which did not work or worked for a short time. Duke started her on Avastin and CPT 11 in June 2005. It also worked for about 3 months. She passed away in October of 2005, 15 months after the diagnosis. Everyone's experience is different. I wish you and your father well.

RE: Avastin and Gbm

by Firstborn on Wed Feb 14, 2007 12:00 AM

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I am also interested in info. on Advastin and BCNU for treatment of GBM stage 4.  My father has undergone 2 resections in 3 years.  After the first surgery he used Temador and Radiation for 1 year, no reoccurance for 8 months after treamtent ended.  He had his 2nd resection in may 2006.  Was put on BCNU and Phlimide, after 2 months 2 tumors were seen on MRI.  He was then put on the combimation of Avastin and CPT11 for the past  4 months, shrinkage of tumors occured on the first MRI (2 months of treatment) then last MRI showed tumor growth of app. 1 cm. Now they are going to try Avastin and BCNU with a new MRI to be done next month.  Does anyone have any info on the combination of BCNU and Avastin??  Would love to hear from you.

RE: Avastin and Gbm

by kayakjack on Tue Jan 20, 2009 12:00 AM

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Dear Hope I can only relay my experience with temodar. Failed the clinical trial with a new onset seizure like symptoms which brought me into ER . which revealed a new lima bean sized tumor within my surgical cavity. Awaiting Avastin approval through insurance, awaiting setup for cyberknife. I have had a positive impact using my tumor to take opportunity to speak at events and to become a voice of hope with ACS relay for life I believe that it is my calling and thank God today I am still alive and can still make a difference in the lives of others See my participant page for more info www.relayforlife.org/elkton
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