Improving the efficacy of radiation therapy

I thought this was interesting for those who might be considering radiation therapy:

Radiation Oncology Physicians:

http://www.mdanderson.org/departments/radiation/display.cfm?

• ....My own laboratory work has been looking at the effect of RU486 as a radiation sensitizer in estrogen and progesterone receptor positive MCF-7 breast cancer cells.  We have found that breast cancer cells pretreated with RU486, an anti-progesterone, have increased sensitivity to killing with irradiation.  The cellular mechanism and potential cross-talk with p53 and apoptotic pathways is currently being investigated....