pls suggest me

my sister is 44 years old ..ans she is weak in nature from her childhood now the problem is she was suffering from high feaver from 7 th of May 2009 so we went to doc and he said to go through an usg of whole abdomen and ct scan.

From which he reveal that there is a mass in gallbladder fossa  and few suspicious nodes which obstracting total view of gall bladder.

He is also confirming that it has the malignancy.

I am at Kolkata India and discussed with 2 More Doc and they also said there is nothing to do more and asked us for Ct guided FNAC.

Now can any body help me by suggesting what should I do now I am really scared to go for further investigation or any thing related to surgery.I feel that her physical status will not be able to bear the pressure of operation..

please suggest me..

Regards,,

sonjoy roy

Hi dear,

 I know that it is very hard for you to believe that your 44 years old sister is suffering from Gall bladder cancer. I know the pain. My beloved mom has just been diagnosed with stage IV GB cancer. She is totally asymtomatic and we found this on routine USG abdomen. 

The most important for you at this time is to determine the stage of GB cancer. Ask your doctors to determine the stage of GB cancer. If you sister has few suspicious nodes, then she might have crossed stage II and might be in stage III. Up to stage II surgery can be done which will be a major surgery removing part of liver with Gallbladder and nodes around GB. The role of surgery is not there in stage III and stage IV. 

If your oncosurgeon is advicing you to for the surgery, if the rumor is fairly localized then you should go ahead with it. For Gb cancer, surgery is the only way to treat the cancer and remove the GB. GB cancer is very aggressive and without surgery/chemo, it will spread in couple of months. 

On the other hand your sister might not be suitable candidate for chemo because as you said, she is very weak. Gemcitabin with cisplatin is standard regimen for advanced GB cancer. Gemcitabin is relatively safer drug compared to some other chemo drugs. no hair loss with Gemcitabin, very few nause and vomitting which can be controlled with prior medication, very few drop in WBC count which comes back to normal once the drug is stopped. 

So ask your doctor about the benefit vs adverse effect of surgery as well as chemo. Because without doing anything GB cancer will spread lightening fast. 

Good luck adn will pray for your sister.