Afinitor

Wanted to know if anyone has been taking afinitor for RCC and how they are doing. My dad is going to start next week and looking for any comments or information that might be helpful.

 

On 7/18/2009 timpatcat wrote:

Wanted to know if anyone has been taking afinitor for RCC and how they are doing. My dad is going to start next week and looking for any comments or information that might be helpful.

My husband has been on Afinitor for five weeks. The side effects have been tolerable and somewhat different than what he experienced on Sutent. He continues to have nosebeelds and footsores. although not as severe He coughs alot,  especially after dinner and before he goes to sleep. Also he has gotten some pimples on his neck and cracks in the folds of skin behind his ears. Keep us posted on your dad's progress.

Sharencec

Thanks for the information, hopefully this will begin to work as good as the Sutent did for 3 years.  He has recently learned he has lesions in brain though (very scary). He is going in to have a consult for laser pinpoint radiation this week, hopefully it will work because I am under the impression that all these different RCC meds do not work for mets to brain.

hi can anyone tell us what symptoms you had before they found mets to the brain? our onc have never scanned his bones or brain and he has been on sutent for 3 years now--in lymph node behind his good kidney and in the lungs but sutent has kept it at same place for 3 years now but he  is tired and frustrated that nothing is getting smaller and he feels bad every day--we are grasteful he is alive but he iswanting to try some of the newer drugs like the avastin which we have heard personally has worked great one woman it reduced or disappeared 40-50 tumors in her lungs and on her rib wow ---would appreciate any info thanks sue

On 7/18/2009 timpatcat wrote:

Thanks for the information, hopefully this will begin to work as good as the Sutent did for 3 years.  He has recently learned he has lesions in brain though (very scary). He is going in to have a consult for laser pinpoint radiation this week, hopefully it will work because I am under the impression that all these different RCC meds do not work for mets to brain.

 

 

On 7/18/2009 Sharencec wrote:

 

On 7/18/2009 timpatcat wrote:

Wanted to know if anyone has been taking afinitor for RCC and how they are doing. My dad is going to start next week and looking for any comments or information that might be helpful.

My husband has been on Afinitor for five weeks. The side effects have been tolerable and somewhat different than what he experienced on Sutent. He continues to have nosebeelds and footsores. although not as severe He coughs alot,  especially after dinner and before he goes to sleep. Also he has gotten some pimples on his neck and cracks in the folds of skin behind his ears. Keep us posted on your dad's progress.

Sharencec

 

If you experience coughing, you're supposed to check with your doctor as it could be one of the common side-effects of developing pneumonitis, which could progress to a more serious pneumonia if left untreated!

I have papillary Type 1 RCC, and after a FAILED attempt with AGS-003 clinical trial along with Sutent, I switched over to Afinitor since July 24 (one week).  I haven't noticed any side effects except for altered taste, slight nausea sometimes, and major fatigue.  I've heard good things about this drug, people.  Most people either experience Stable Disease or Partial Response.

Please post your results with your histology here!

 

On 8/1/2009 krlhc8 wrote:

I have papillary Type 1 RCC, and after a FAILED attempt with AGS-003 clinical trial along with Sutent, I switched over to Afinitor since July 24 (one week).  I haven't noticed any side effects except for altered taste, slight nausea sometimes, and major fatigue.  I've heard good things about this drug, people.  Most people either experience Stable Disease or Partial Response.

Please post your results with your histology here!

 

As of right know my Dad has not started Afinitor will begin in 1 week, I will let you know about his side effects once he begins. My dad has stage iv rcc with mets to brain, he is having cyber knife radiation this week so he can't start Afinitor until that treatment is over. I have also heard good thing with Afinitor I wish you success

My dad had a seizure which prompted them to do a CatScan which showed mets to brain, not sure why they don't scan brain and lungs when they know if can go there. Dr said if not symptoms they don't scan but I wish they had to try and catch earlier.

 

On 8/1/2009 krlhc8 wrote:

 

On 7/18/2009 Sharencec wrote:

 

On 7/18/2009 timpatcat wrote:

Wanted to know if anyone has been taking afinitor for RCC and how they are doing. My dad is going to start next week and looking for any comments or information that might be helpful.

My husband has been on Afinitor for five weeks. The side effects have been tolerable and somewhat different than what he experienced on Sutent. He continues to have nosebeelds and footsores. although not as severe He coughs alot,  especially after dinner and before he goes to sleep. Also he has gotten some pimples on his neck and cracks in the folds of skin behind his ears. Keep us posted on your dad's progress.

Sharencec

 

If you experience coughing, you're supposed to check with your doctor as it could be one of the common side-effects of developing pneumonitis, which could progress to a more serious pneumonia if left untreated!

Thanks for the warning. My husband did see his doctors. X-ray showed clear lungs. He is taking OTC cough suppressants under doctors' care.