positive for angiolymphatic invasion

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positive for angiolymphatic invasion

by andreasa69 on Mon Aug 03, 2009 12:00 AM

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Hello,

<first post>.

I was diagnosed with papillary thyca in late May and had a full thyroidectomy done on July 22nd. Seeing that we had a positive result for thyca ahead of the surgery, surgeons went a little more aggressive and removed the entire thyroid, along with something called an area 6 scan (maybe I have the wording wrong). Some lymph glands in right side of the neck were also removed, as well as 2 parathyroids and a lymph node were removed to be biopsied. I know that surgeon mentioned having to cutout some "muscle" in the neck as the tumour had attached to it (I forget the name).

I met with him today to review the path reports. In brief, lymph node was negative, parathyroids were negative, however the report shows positive for angiolymphatic invasion. Not sure what that means, and was wondering if anyone who has gone through the same thing had a similar diagnosis on their report. Surgeon said, that he is confident that the surgery was a success and that the cancer was removed as during surgery he was able to cut "around it" and pat reports show the surrounding area to be clean (again sorry if this sounds jiberish as I still don't have the actual report in front of me to use the actual medical term). Tumour was 2cm x 1.2cm x 1.4cm.

That said, I will have to go through I-131 treatment when the surgery has healed. He mentioned that because of the invasion, the cancer was more aggressive and will most probably require a higher dose of 150 mCi to "mop up everything" which will mean isolation in the hospital (I meet with the endocrinologist next week to get more details).

Question - What does this mean: positive for angiolymphatic invasion?

Staying positive, pun intended :)

Thanks in advance!

Andre.

 

RE: positive for angiolymphatic invasion

by dinparadise on Mon Aug 03, 2009 12:00 AM

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angioinvasion

Synonyms: angiolymphatic invasion

Definition: (an-gee-o-in-VAY-shun) When there are signs that the cancer has invaded blood vessels or lymph vessels.

That's all I could find.  Google it and you'll get more information

RE: positive for angiolymphatic invasion

by andreasa69 on Thu Aug 06, 2009 12:00 AM

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Hmmmmmmm, that doesn't sound all that good, surgeon however told me that the surgery was a complete success, and that I would be doing RAI just to "mop" everything up, but because of this I'd have to do teh higher dose.

Anyone else have this show on their pathology reports following the TT?

RE: positive for angiolymphatic invasion

by Babymou on Tue Aug 11, 2009 12:00 AM

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Hi,

 

I found this on another site (women's BC):

 


I had this written on my pathology report: "angio/lymphatic invasion has been identified". I did not know what it meant but I knew it was not good news. The very word "invasion" in any context implies aggressiveness.
 
I have since found out that what the description on the pathology report means is that the tumor had the means to "travel" to either the lymph nodes or the blood stream. It had the means to travel. It does not mean it did travel. My nodes were clear so my main concern was the blood stream. That is why I chose chemo. 
  
 
Good luck and keep in touch.

 Hope it makes sense!

 

RE: positive for angiolymphatic invasion

by Just_Diagnosed on Wed Aug 12, 2009 12:00 AM

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On 8/3/2009 andreasa69 wrote:

Hello,

<first post>.

I was diagnosed with papillary thyca in late May and had a full thyroidectomy done on July 22nd. Seeing that we had a positive result for thyca ahead of the surgery, surgeons went a little more aggressive and removed the entire thyroid, along with something called an area 6 scan (maybe I have the wording wrong). Some lymph glands in right side of the neck were also removed, as well as 2 parathyroids and a lymph node were removed to be biopsied. I know that surgeon mentioned having to cutout some "muscle" in the neck as the tumour had attached to it (I forget the name).

I met with him today to review the path reports. In brief, lymph node was negative, parathyroids were negative, however the report shows positive for angiolymphatic invasion. Not sure what that means, and was wondering if anyone who has gone through the same thing had a similar diagnosis on their report. Surgeon said, that he is confident that the surgery was a success and that the cancer was removed as during surgery he was able to cut "around it" and pat reports show the surrounding area to be clean (again sorry if this sounds jiberish as I still don't have the actual report in front of me to use the actual medical term). Tumour was 2cm x 1.2cm x 1.4cm.

That said, I will have to go through I-131 treatment when the surgery has healed. He mentioned that because of the invasion, the cancer was more aggressive and will most probably require a higher dose of 150 mCi to "mop up everything" which will mean isolation in the hospital (I meet with the endocrinologist next week to get more details).

Question - What does this mean: positive for angiolymphatic invasion?

Staying positive, pun intended :)

Thanks in advance!

Andre.

 


I, too, have anioinvasion. I was initially diagnosed with Hurthle Cell Ca, which has worse stats than papillary or follicular. I ended up at a major cancer hosp. that specializes due to this and my local doc's inability to answer my questions. I read a ton of research when I was first diagnosed in April, and much of it focused on the extent of angoinvasion as the biggest predictor of future aggressiveness. I worried myself sick over this, especially since my local doctors did not feel as though it was an issue. I have been told, and have read that papillary/follicular variant with the vascular invasion sometimes tends to act more like pure follicular, which can be statistically a little more aggressive.

I had my completion surgery at out of state at the other hospital, and ended up with 2 other cancerous nodules on the other side. The redo of my path report (by them) came back with 7 foci of invasion (7 locations). My surgeon and endo up there say that mine qualifies (and then some) for the "extensive vascular invasion" label (anything 4 or more places). It was also changed from Hurthle Cell to Pap. follic. variant. I never would have known that without the 2nd opinion. I am told by them that they believe at this point that I still have a good prognosis, but that the RAI/wbs will tell them more about potential aggressiveness (and probability of recurrence). Different docs have called my level of vascular invasion "scary", and said that it was a "nasty feature to have". Mine also has oncocytic (hurthle) features, and i hope that does not affect its ability to uptake the RAI.

I do realize that most people with vascular invasion don't have it to the extent that I did, but I am saying this because it really helped me (even if just my piece of mind) to get a 2nd, more expert opinion. It had even been suggested that I should consider leaving the other half of my thyroid in b/c I was only 33 and it was "encapsulated" and my margins were clear. They said I shouldn't have anything else to worry about...and there were already 2 other cancerous nodules on the other side.

Having the invasion (especially to a higher degree) does not really change the treatment plan, as long as you have the entire thyroid out AND RAI. It just means that you really need to be diligent about following up and making sure you get your recommended labs and scans, etc. I am hoping that mine hasn't already started to float off anywhere else, and if I am clear after the WBS, I plan to ask if my doc will mind seeing me a little more frequently than twice per year (maybe every 4 months instead of 6). I don't say this to scare you, I just became so frustrated because everything my original doctors told me seemed to conflict with everything I was reading. You just have to educate yourself, be pro-active, and be your own advocate.

Thanks,
Stephanie 

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