I am a former smoker from college. I smoked 5 or 6 yrs ago, grew up around 2nd hand smoke as a child, if you want to know that. I'm on tarceva and it seems to be working. I am 30 yrs old and have been on Tarceva since April. My stage 3 cancer is stabilized. I had one lymph removed and it was WAY dead so that's a good sign. I do have naseau, the runs and the wrost imaginable acne a person could have. More acne than when I was in puberty. But I think acne and the runs, sure does beat the alternative. Good luck and God bless you and see you through this journey.