Hi! I'm so sorry that your Zoe is having so many problems. I hope that this round of Baytril helps her. If not, I would begin the testing process to check for bladder cancer (TCC). That process might include a urine test, an xray, an ultrasound and possibly a scope to look in her bladder. My Willie went through something similar in 6-08. A small tumor was located and removed from his bladder shortly after that. The tumor was malignant. He has been taking piroxicam with stomach protectors since then. The cost of the piroxicam (Willie is a Westie and weighs about 21 lbs) is about $25 a month. It has to be compounded into the right dosage and put in a capsule. I'm not sure if there is a less expensive way to get the correct dose for our little sweeties. I haven't given him anything else except Carafate, Pepcid and Pepto Bismol.....all to help protect his stomach and intestines from the piroxicam. He usually takes five days of piroxicam and then takes a day off, then start again. So far, so good. He is having another utlrasound tomorrow to see how he's doing. I tell you all this to let you know that there is hope that a treatment (not cure) can be found IF your Zoe indeed does have TCC. There are others on this board who have successfully used graviola. You can find out more about it by reading through the back posts.
If you live near a vet school or in a big city, you may be able to find a cancer treatment center that can diagnose and treat your Zoe. There are people who post here who have had wonderful results taking their precious dogs to specialists for treatment. I have continued to use my Willie's own vet for his treatment because my vet stays up-to-date on the latest treatments available and is in touch with the oncologists at the nearest vet school on a regular basis.
It may help you to know that frequent urination, often without much urine being passed, is a symptom and side effect of bladder problems. Accidents also fall into that category. I would tell my vet about all this type of activity that you notice.
You and Zoe will be in my thoughts and prayers. Please let us know how you both are doing!
Sue