Carcinoid synndrome

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Carcinoid synndrome

by hopehope1 on Tue Sep 29, 2009 12:00 AM

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Hi everyone. I am a female who has just turned 33. I am panicking at the moment. Have been fatigued since the birth of my son a year ago, but put that down to sleepless nights etc. Started flushing about three months ago, first just my right ear and then kind of spreading across the face. The flushing itself last for a short while only, but the redness persists. Sometimes my ear and flace flush at the same time, sometimes separately. Dermatologist has ruled out Rosascea. Flushing is brought on by eating and stress. I can feel my heart beat "harder" during flushing. If I eat chocolate or drink Coke I get like a rush of adrenaline or endorphins, sometimes followed by flushing but not always. My face is permanently reddish, but better in the morning. Gets worse as the day goes on. I have never had any skin problems before, have not even had a pimple!! Normal bowel habits, apart from feeling a bit nauseaus at times. Get palpitations when I lie down to go to sleep, and it takes a while for me to actually fall asleep due to this. Have been tested for just about everything. No mastocytosis, no early menopause, 24-hour urine normal, Chromogranin A on higher end of normal, Slightly elevated Pancreatic Polypeptide. CT scans showed nothing. Had an Octreoscan which showed prominent uptake in chest area but within physiological limits. Some uptake in the Pancreatic and adrenal area. Doctor doesn't seem to worried, and he is on holiday in Europe for 4 weeks. Have slightly underactive thyroid, and was given Thyroxine for it, but had a really bad reactin to it; major flushing, heart racing, nearly fainted and husband took me to the hospital (by the time I got there I was feeling better). Stopped taking the medication after two tablets.
I am so scared and stressed about this , as I am only 33 and have a three year old girl and a one year old boy at home that I want to see grow up. Does anyone have any advice as to who to contact about this? Am seeing an endo who seems on the ball but if he gives up, who can I contact?? If I have a carcinoid tumor on my pancreas, I understand that the tests usually come back negative?? Such a mess....
Thanks for your time. Oh, and I am based in Sydney, Australia

RE: Carcinoid synndrome

by Katsen57 on Thu Oct 01, 2009 12:00 AM

Quote | Reply

 

On 9/29/2009 hopehope1 wrote:

Hi everyone. I am a female who has just turned 33. I am panicking at the moment. Have been fatigued since the birth of my son a year ago, but put that down to sleepless nights etc. Started flushing about three months ago, first just my right ear and then kind of spreading across the face. The flushing itself last for a short while only, but the redness persists. Sometimes my ear and flace flush at the same time, sometimes separately. Dermatologist has ruled out Rosascea. Flushing is brought on by eating and stress. I can feel my heart beat "harder" during flushing. If I eat chocolate or drink Coke I get like a rush of adrenaline or endorphins, sometimes followed by flushing but not always. My face is permanently reddish, but better in the morning. Gets worse as the day goes on. I have never had any skin problems before, have not even had a pimple!! Normal bowel habits, apart from feeling a bit nauseaus at times. Get palpitations when I lie down to go to sleep, and it takes a while for me to actually fall asleep due to this. Have been tested for just about everything. No mastocytosis, no early menopause, 24-hour urine normal, Chromogranin A on higher end of normal, Slightly elevated Pancreatic Polypeptide. CT scans showed nothing. Had an Octreoscan which showed prominent uptake in chest area but within physiological limits. Some uptake in the Pancreatic and adrenal area. Doctor doesn't seem to worried, and he is on holiday in Europe for 4 weeks. Have slightly underactive thyroid, and was given Thyroxine for it, but had a really bad reactin to it; major flushing, heart racing, nearly fainted and husband took me to the hospital (by the time I got there I was feeling better). Stopped taking the medication after two tablets.
I am so scared and stressed about this , as I am only 33 and have a three year old girl and a one year old boy at home that I want to see grow up. Does anyone have any advice as to who to contact about this? Am seeing an endo who seems on the ball but if he gives up, who can I contact?? If I have a carcinoid tumor on my pancreas, I understand that the tests usually come back negative?? Such a mess....
Thanks for your time. Oh, and I am based in Sydney, Australia

Dear hopehope1:  Do not panick,  I was only 40 whin I was Diagnosed You need to stay stress free as much as possible.  Carcinoid is very complex.  I would suggest speaking with Dr. Warner in New York City. Call his # @ 212-241-4299  He may be able to tell you who to see since you live "Down Under".  You want to see somone who specializes in Carcinoid.  There is an issue with carcinoid that may effect your heart.  The tumors release what is called Seratonin.  This is naturally produced in the body but since the tumors release more of it you could have excessive amounts.  I had 5 times the amount than a "normal" human should have before I had my primary removed. I was put on a med called SANDOSTATIN made by Novartis Pharmaceuticals.  This will help supress the large doses of Seratonin.  The other thing about having large amounts of Seratonin is that it could damage your heart valves on the right side.  Your blood travels from the right side of your heart, up, over and into the bottom of your lungs than through the left side of the heart valves.  I have an issue where I have a tiny hole in my heart so I had a simple test done to see if the hole was large enough to let the blood (and seratonin) leak from the right to the left without getting absorbed by the lung first.  It wasn't the case so I was OK for that.  But it is important to see a cardiologist who knows how to treat Carcinoid.  The other thing is that you should never have Epinephrine, Ever!,  This may cause Severe Increase or Decrease in your blood pressure and may kill you (Called Carcinoid Crisis).  Dentists use it in novacane so be very carefull about that.  Get a medical bracelett that says no epinephrine on it if infact you do have carcinoid.  and be sure to let any one doing any procedure on you that you may or do have Carcinoid and should be noted on your charts that you should not have Epinephrine.  Most people I have spoken with have had flushing after they ate.  Also if drinking red wine may be a trigger to flushing.  Some people have no symptoms at all which is A-Typical but should be checked anyway.  It is importatnto get the primary.  You should read all the messages in this forum and also check out the ACOR web site it has a forum and may be of help to you also.  There is also a test called a pancreostatin test the is a molecular version or more precise test that can detect your "markers" better than a (CGA) Gromogranin A test.  Avoid  eating foods naturaly high in seratonin like Bananas, pineapple, nuts, avacado, tomato, chocolate, cafine.  When you took a 5HIAA Urine test they should have given you a list of foods to avoid while taking this test. I wish you all the best.  Katsen

RE: Carcinoid synndrome

by diannaboom on Thu Oct 01, 2009 12:00 AM

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 Dear "Panicked"...I know exactly how you feel!  That panic is understandable!  We fellow survivors have all been there!  Here is an email address for a lady in Australia who is actively involved in starting support groups "down under" for carcinoid and neuroendocrine tumors!  Jenny is great and should be able to refer you to some good folks who can help!  

Jenny M. <

  • Delete email address and replace with the below:
--Message edited by CancerCompass staff. For personal protection, email address removed. Consider private reply. Please review CancerCompass Member Guidelines at http://www.cancercompass.com/common/guidelines.html--

>

Much luck...try to keep calm.  This disease does give us time to research and find the best docs and treatments for us as individuals!  Hugs to you and yours!  Dianna

On 10/1/2009 Katsen57 wrote:

 

On 9/29/2009 hopehope1 wrote:

Hi everyone. I am a female who has just turned 33. I am panicking at the moment. Have been fatigued since the birth of my son a year ago, but put that down to sleepless nights etc. Started flushing about three months ago, first just my right ear and then kind of spreading across the face. The flushing itself last for a short while only, but the redness persists. Sometimes my ear and flace flush at the same time, sometimes separately. Dermatologist has ruled out Rosascea. Flushing is brought on by eating and stress. I can feel my heart beat "harder" during flushing. If I eat chocolate or drink Coke I get like a rush of adrenaline or endorphins, sometimes followed by flushing but not always. My face is permanently reddish, but better in the morning. Gets worse as the day goes on. I have never had any skin problems before, have not even had a pimple!! Normal bowel habits, apart from feeling a bit nauseaus at times. Get palpitations when I lie down to go to sleep, and it takes a while for me to actually fall asleep due to this. Have been tested for just about everything. No mastocytosis, no early menopause, 24-hour urine normal, Chromogranin A on higher end of normal, Slightly elevated Pancreatic Polypeptide. CT scans showed nothing. Had an Octreoscan which showed prominent uptake in chest area but within physiological limits. Some uptake in the Pancreatic and adrenal area. Doctor doesn't seem to worried, and he is on holiday in Europe for 4 weeks. Have slightly underactive thyroid, and was given Thyroxine for it, but had a really bad reactin to it; major flushing, heart racing, nearly fainted and husband took me to the hospital (by the time I got there I was feeling better). Stopped taking the medication after two tablets.
I am so scared and stressed about this , as I am only 33 and have a three year old girl and a one year old boy at home that I want to see grow up. Does anyone have any advice as to who to contact about this? Am seeing an endo who seems on the ball but if he gives up, who can I contact?? If I have a carcinoid tumor on my pancreas, I understand that the tests usually come back negative?? Such a mess....
Thanks for your time. Oh, and I am based in Sydney, Australia

Dear hopehope1:  Do not panick,  I was only 40 whin I was Diagnosed You need to stay stress free as much as possible.  Carcinoid is very complex.  I would suggest speaking with Dr. Warner in New York City. Call his # @ 212-241-4299  He may be able to tell you who to see since you live "Down Under".  You want to see somone who specializes in Carcinoid.  There is an issue with carcinoid that may effect your heart.  The tumors release what is called Seratonin.  This is naturally produced in the body but since the tumors release more of it you could have excessive amounts.  I had 5 times the amount than a "normal" human should have before I had my primary removed. I was put on a med called SANDOSTATIN made by Novartis Pharmaceuticals.  This will help supress the large doses of Seratonin.  The other thing about having large amounts of Seratonin is that it could damage your heart valves on the right side.  Your blood travels from the right side of your heart, up, over and into the bottom of your lungs than through the left side of the heart valves.  I have an issue where I have a tiny hole in my heart so I had a simple test done to see if the hole was large enough to let the blood (and seratonin) leak from the right to the left without getting absorbed by the lung first.  It wasn't the case so I was OK for that.  But it is important to see a cardiologist who knows how to treat Carcinoid.  The other thing is that you should never have Epinephrine, Ever!,  This may cause Severe Increase or Decrease in your blood pressure and may kill you (Called Carcinoid Crisis).  Dentists use it in novacane so be very carefull about that.  Get a medical bracelett that says no epinephrine on it if infact you do have carcinoid.  and be sure to let any one doing any procedure on you that you may or do have Carcinoid and should be noted on your charts that you should not have Epinephrine.  Most people I have spoken with have had flushing after they ate.  Also if drinking red wine may be a trigger to flushing.  Some people have no symptoms at all which is A-Typical but should be checked anyway.  It is importatnto get the primary.  You should read all the messages in this forum and also check out the ACOR web site it has a forum and may be of help to you also.  There is also a test called a pancreostatin test the is a molecular version or more precise test that can detect your "markers" better than a (CGA) Gromogranin A test.  Avoid  eating foods naturaly high in seratonin like Bananas, pineapple, nuts, avacado, tomato, chocolate, cafine.  When you took a 5HIAA Urine test they should have given you a list of foods to avoid while taking this test. I wish you all the best.  Katsen


 

RE: Carcinoid synndrome

by rn460 on Fri Oct 16, 2009 12:00 AM

Quote | Reply

 

On 10/1/2009 Katsen57 wrote:

 

On 9/29/2009 hopehope1 wrote:

Hi everyone. I am a female who has just turned 33. I am panicking at the moment. Have been fatigued since the birth of my son a year ago, but put that down to sleepless nights etc. Started flushing about three months ago, first just my right ear and then kind of spreading across the face. The flushing itself last for a short while only, but the redness persists. Sometimes my ear and flace flush at the same time, sometimes separately. Dermatologist has ruled out Rosascea. Flushing is brought on by eating and stress. I can feel my heart beat "harder" during flushing. If I eat chocolate or drink Coke I get like a rush of adrenaline or endorphins, sometimes followed by flushing but not always. My face is permanently reddish, but better in the morning. Gets worse as the day goes on. I have never had any skin problems before, have not even had a pimple!! Normal bowel habits, apart from feeling a bit nauseaus at times. Get palpitations when I lie down to go to sleep, and it takes a while for me to actually fall asleep due to this. Have been tested for just about everything. No mastocytosis, no early menopause, 24-hour urine normal, Chromogranin A on higher end of normal, Slightly elevated Pancreatic Polypeptide. CT scans showed nothing. Had an Octreoscan which showed prominent uptake in chest area but within physiological limits. Some uptake in the Pancreatic and adrenal area. Doctor doesn't seem to worried, and he is on holiday in Europe for 4 weeks. Have slightly underactive thyroid, and was given Thyroxine for it, but had a really bad reactin to it; major flushing, heart racing, nearly fainted and husband took me to the hospital (by the time I got there I was feeling better). Stopped taking the medication after two tablets.
I am so scared and stressed about this , as I am only 33 and have a three year old girl and a one year old boy at home that I want to see grow up. Does anyone have any advice as to who to contact about this? Am seeing an endo who seems on the ball but if he gives up, who can I contact?? If I have a carcinoid tumor on my pancreas, I understand that the tests usually come back negative?? Such a mess....
Thanks for your time. Oh, and I am based in Sydney, Australia

Dear hopehope1:  Do not panick,  I was only 40 whin I was Diagnosed You need to stay stress free as much as possible.  Carcinoid is very complex.  I would suggest speaking with Dr. Warner in New York City. Call his # @ 212-241-4299  He may be able to tell you who to see since you live "Down Under".  You want to see somone who specializes in Carcinoid.  There is an issue with carcinoid that may effect your heart.  The tumors release what is called Seratonin.  This is naturally produced in the body but since the tumors release more of it you could have excessive amounts.  I had 5 times the amount than a "normal" human should have before I had my primary removed. I was put on a med called SANDOSTATIN made by Novartis Pharmaceuticals.  This will help supress the large doses of Seratonin.  The other thing about having large amounts of Seratonin is that it could damage your heart valves on the right side.  Your blood travels from the right side of your heart, up, over and into the bottom of your lungs than through the left side of the heart valves.  I have an issue where I have a tiny hole in my heart so I had a simple test done to see if the hole was large enough to let the blood (and seratonin) leak from the right to the left without getting absorbed by the lung first.  It wasn't the case so I was OK for that.  But it is important to see a cardiologist who knows how to treat Carcinoid.  The other thing is that you should never have Epinephrine, Ever!,  This may cause Severe Increase or Decrease in your blood pressure and may kill you (Called Carcinoid Crisis).  Dentists use it in novacane so be very carefull about that.  Get a medical bracelett that says no epinephrine on it if infact you do have carcinoid.  and be sure to let any one doing any procedure on you that you may or do have Carcinoid and should be noted on your charts that you should not have Epinephrine.  Most people I have spoken with have had flushing after they ate.  Also if drinking red wine may be a trigger to flushing.  Some people have no symptoms at all which is A-Typical but should be checked anyway.  It is importatnto get the primary.  You should read all the messages in this forum and also check out the ACOR web site it has a forum and may be of help to you also.  There is also a test called a pancreostatin test the is a molecular version or more precise test that can detect your "markers" better than a (CGA) Gromogranin A test.  Avoid  eating foods naturaly high in seratonin like Bananas, pineapple, nuts, avacado, tomato, chocolate, cafine.  When you took a 5HIAA Urine test they should have given you a list of foods to avoid while taking this test. I wish you all the best.  Katsen

Hi Katsen,

It is always nice in some way to meet new people with this rare cancer we have.  I was curious why you think Sloan doesnt offer the care that St.lukes does? Please dont take it as a argument I am curious on your research cause it seems there really is no deffinate answer to this cancer and they all think they know best. We are dealing more with there big ego's the our cancer at times...

 

 

RE: Carcinoid synndrome

by Katsen57 on Fri Oct 16, 2009 12:00 AM

Quote | Reply

 

On 10/16/2009 rn460 wrote:

 

On 10/1/2009 Katsen57 wrote:

 

On 9/29/2009 hopehope1 wrote:

Hi everyone. I am a female who has just turned 33. I am panicking at the moment. Have been fatigued since the birth of my son a year ago, but put that down to sleepless nights etc. Started flushing about three months ago, first just my right ear and then kind of spreading across the face. The flushing itself last for a short while only, but the redness persists. Sometimes my ear and flace flush at the same time, sometimes separately. Dermatologist has ruled out Rosascea. Flushing is brought on by eating and stress. I can feel my heart beat "harder" during flushing. If I eat chocolate or drink Coke I get like a rush of adrenaline or endorphins, sometimes followed by flushing but not always. My face is permanently reddish, but better in the morning. Gets worse as the day goes on. I have never had any skin problems before, have not even had a pimple!! Normal bowel habits, apart from feeling a bit nauseaus at times. Get palpitations when I lie down to go to sleep, and it takes a while for me to actually fall asleep due to this. Have been tested for just about everything. No mastocytosis, no early menopause, 24-hour urine normal, Chromogranin A on higher end of normal, Slightly elevated Pancreatic Polypeptide. CT scans showed nothing. Had an Octreoscan which showed prominent uptake in chest area but within physiological limits. Some uptake in the Pancreatic and adrenal area. Doctor doesn't seem to worried, and he is on holiday in Europe for 4 weeks. Have slightly underactive thyroid, and was given Thyroxine for it, but had a really bad reactin to it; major flushing, heart racing, nearly fainted and husband took me to the hospital (by the time I got there I was feeling better). Stopped taking the medication after two tablets.
I am so scared and stressed about this , as I am only 33 and have a three year old girl and a one year old boy at home that I want to see grow up. Does anyone have any advice as to who to contact about this? Am seeing an endo who seems on the ball but if he gives up, who can I contact?? If I have a carcinoid tumor on my pancreas, I understand that the tests usually come back negative?? Such a mess....
Thanks for your time. Oh, and I am based in Sydney, Australia

Dear hopehope1:  Do not panick,  I was only 40 whin I was Diagnosed You need to stay stress free as much as possible.  Carcinoid is very complex.  I would suggest speaking with Dr. Warner in New York City. Call his # @ 212-241-4299  He may be able to tell you who to see since you live "Down Under".  You want to see somone who specializes in Carcinoid.  There is an issue with carcinoid that may effect your heart.  The tumors release what is called Seratonin.  This is naturally produced in the body but since the tumors release more of it you could have excessive amounts.  I had 5 times the amount than a "normal" human should have before I had my primary removed. I was put on a med called SANDOSTATIN made by Novartis Pharmaceuticals.  This will help supress the large doses of Seratonin.  The other thing about having large amounts of Seratonin is that it could damage your heart valves on the right side.  Your blood travels from the right side of your heart, up, over and into the bottom of your lungs than through the left side of the heart valves.  I have an issue where I have a tiny hole in my heart so I had a simple test done to see if the hole was large enough to let the blood (and seratonin) leak from the right to the left without getting absorbed by the lung first.  It wasn't the case so I was OK for that.  But it is important to see a cardiologist who knows how to treat Carcinoid.  The other thing is that you should never have Epinephrine, Ever!,  This may cause Severe Increase or Decrease in your blood pressure and may kill you (Called Carcinoid Crisis).  Dentists use it in novacane so be very carefull about that.  Get a medical bracelett that says no epinephrine on it if infact you do have carcinoid.  and be sure to let any one doing any procedure on you that you may or do have Carcinoid and should be noted on your charts that you should not have Epinephrine.  Most people I have spoken with have had flushing after they ate.  Also if drinking red wine may be a trigger to flushing.  Some people have no symptoms at all which is A-Typical but should be checked anyway.  It is importatnto get the primary.  You should read all the messages in this forum and also check out the ACOR web site it has a forum and may be of help to you also.  There is also a test called a pancreostatin test the is a molecular version or more precise test that can detect your "markers" better than a (CGA) Gromogranin A test.  Avoid  eating foods naturaly high in seratonin like Bananas, pineapple, nuts, avacado, tomato, chocolate, cafine.  When you took a 5HIAA Urine test they should have given you a list of foods to avoid while taking this test. I wish you all the best.  Katsen

Hi Katsen,

It is always nice in some way to meet new people with this rare cancer we have.  I was curious why you think Sloan doesnt offer the care that St.lukes does? Please dont take it as a argument I am curious on your research cause it seems there really is no deffinate answer to this cancer and they all think they know best. We are dealing more with there big ego's the our cancer at times...

 

 

Dear HopeHope1, Don't get me wrong, Sloan-Kettering is a great hospital for treating cancer.  I only say that Sloan-Kettering doesn't really treat Carcinoid because many of the patients that have been to our support group meetings have said they haven't been treated with the same techniques as others who have gone to other Dr.s around the region.  We have several new patients that come in and they have been told to not worry too much about this cancer because it is "Slow Growing" and they don't know what to do or have any other direction and when they come to the Support group they are really confused about why this is.  For some reason the Head Dr. at Sloan has a different view from Dr. Warner and does not accept his line of thinking on Carcinoid.  Our theory is that Sloan-Kettering is only interested in giving a cancer patient a certain goal of life expectancy of say 5 years.  Well for a Breast Cancer patient that is a great outcome because it is such an aggressive cancer that needs immediate action.  With carcinoid, even if you don't get Surgery after diagnosis you will probably have an automatic life expectancy of 5 years so on paper this looks great for the Dr.s because it meets their goal.  But Carcinoid is the complete opposite of any other cancer.  Many people can live with liver mets and be treated with many different therapies that can prolong life for many more years.  We (the support group) don't understand why they think like that,  but we want people into understand not all cancers are alike and should maybe look in other directions.  After all, don't you want to make the best choice for your health that is available.  You are you own best advocate.  You have to make the best choice for you.  If you like the dr. you are with, great. I myself changed to another oncologist that has more interest and knowledge in Carcinoid and he has a great relationship with Dr. Warner. We  want Carcinoid Patients to know there are other alternatives out there.  Some people have lived with this disease for 15 to 20 years.  I myself have only been diagnosed 2 1/2 yrs ago.  But I probably have had this for 10 years considering the primary was the size of a lemon.  It ultimately is the patients decision, we just want people to know there are other alternatives out there.  Some people have gone to Europe for treatment.  I would too if I could afford it. I don't want you to think I am against Sloan-Kettering, I am Not.  I am only speaking from the things I have learned from other patients experiences.  I wish you the best of health and God Bless.  Katsen57 

 

RE: Carcinoid synndrome

by rn460 on Sat Oct 17, 2009 12:00 AM

Quote | Reply

Hi Katsen,

I am very interested in what you or the other pts. you have met have done as far as treaments for carcniod?  Have you done chemo any sucess? What exactly besides the monthly injections are being done diffrently? I am asking you cause I dont live close to a support group and have heard the opossite from what you are writing by several doctors. Please by no means am i saying your wrong. Im asking if you know what they are doing please tell me so I can get on that wagon if you and other are getting sucess from it!

My cancer started in my rectum which was taken removed by surgery. 4 months later a catscan showed 3 spots in my liver and a soft tissue mass in my pelvis. St. Lukes said I must have chemo or I will die in 5yrs.  They aslo told me with chemo I would never get rid of it but can buy a few yrs. Folfox is what they wanted to use. Now my doctors at Columbia, Sloan and Boston both said that was crazy. Not only was it the most inappropiate chemo to use but the rate of sucess is near zero.

Thanks

RE: Carcinoid synndrome

by hopehope1 on Sun Oct 18, 2009 12:00 AM

Quote | Reply

Thank you all for your replies. I need to go to the dentist for a filling, can they not give me any anaestethic at all or are there alternatives?? The endocronologist I am seeing at the moment is on a four week holiday in Europe so I will just have to wait and see what the next step would be. I have in fact already emailed a lovely lady down under, Jen, who was able to ease my panic a little. She has had the syndrome for 20 years, and is still doing ok by the sounds of things. It is probably not the norm, but then it is also not impossible that you can live for a long time with the disease. I just want to be around for my baby and toddler, otherwise I wouldn't have been in such a mess. It would still suck, but the thought of my children growing up without their mum really distresses me.

Something I can't believe is how many doctors have said that there is nothing wrong with me, that I have lupus/slapped cheek disease/IBS/depression/imagination etc. And that you in the end have to google the symptoms and come up with a list of possible diagnoses to give to the doctor. Sucks.

 

Anyway, thanks so much for your replies

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