Glioblastoma VI - middle of brain

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Glioblastoma VI - middle of brain

by Noneesfame on Thu Oct 01, 2009 12:00 AM

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My mother-in-law (59 years old) was diagnosed with a 4cm by 4cm Glioblastoma..pretty much in the mid-brain.  They performed surgery in late August, removed about 70% and was given a prognosis of about 2 years.  It was pretty invasive.  Since then, she has been unable to move her left side and her speech is limited.  You can understand what she says...but, she doesn't say much and does not initiate the conversation.  She has never lost her appetite through this whole thing (she was on a feeding tube after the surgery for about 2.5 weeks).  She eats okay....but, is fed.  She's in a daze most of the time, and was just moved to the rehab wing of the hospital...where they don't think she's getting any better.  They did a CT Scan the other day and found no swelling or fluid (she had another surgery about a week after her first to insert a shunt as she had fluid).  The tumor is still there...though I don't believe it has grown any.  She is 3/4 of the way done with her 20 treatments of radiation.  She is about 1/2 way done with her Temodar (42 days worth).  The neurologist told us yesterday that she doesn't seem to be getting any better and to prepare ourselves...and that it's just a really bad tumor.  (I don't think there are any good tumors)!  Other than trying to get her on clinical trial...I'm not sure what else to do?

RE: Glioblastoma VI - middle of brain

by Dstew on Thu Oct 01, 2009 12:00 AM

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Prepare of the worst and hope for the best.

 

My dad is about 11 years older and did not go through the surgery as his tumor was deeper and about half the size.   Responded well to the radition and chemo but had a recurrence in August.  What they do not tell you in the hand books on this is that the treatment and side effects, swelling in the feet or blood clots or ... can successfully treat the tumor and yet the patient can get worse.  Sometimes steroids or something else or even time will work and other times, the body starts to shut down because the even though the tumor is no longer growing, the insult to the body is too much.   My dad had the speech problem and the odd problem with numbness and literally in days was in a wheel chair from being able to walk.  The oncologist came into the room after another MRI and told us they took it to the cancer board and had every expert they could look at it because after the initial recurrence, the tumor had not grown so it was anyone's guess why he got worse and had done so quickly.   With the lack of mobility and the sudden weakness plus fatigue, the clinical trial he had signed up for was no longer available and they believe further treatment will do more harm than good.  So also be prepared that they may not qualify for a trial as I also learned that for most, essentially the patient has to be able to walk into that appointment.  Having said that, my dad ran into the same thing in April and an adjustment of his steroids gave him 5 good months of function and ability to live at home without the need for home care.  So prepare for the worst and hope and look for the best.

RE: Glioblastoma VI - middle of brain

by Heritage_Softail on Fri Oct 02, 2009 12:00 AM

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Noneesfame

This i sa tough road for all to travel. She is still in treatment and has to make it through the radiation and temodar. Then they will wait about a month for swelling mostly likely to subside and then perform an MRI. Then any treamtnet is decided from there. It is a wait and see game, sucks. Below is a sight on clinical trials for GBM:

http://clinicaltrials.gov/ct2/results?term=GBM

I wish your family the best and bless your MIL.

Damon

DX Nov 07

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